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Separated by just 279 miles of scenic Tuscan countryside and connecting two of the greatest cultural centres of Europe, the route between these two cities can easily be travelled by bus, train or air. Train travel is usually preferred as the most efficient and frequent way to travel. Buses provide a more economical method without sacrificing too much time. Air travel is generally the slowest way to travel, owing to Rome's airport being located on the Mediterranean coast, some distance from the city.
There are eight buses connecting the cities each day, departing Florence from a stop on the Piazzale Monelungo, which is right next to Florence's Santa Maria Novella train station and accessed by a pedestrian underpass. Buses are operated by Megabus and provide two different routes. The shorter route takes 3 hours and 30 minutes and the alternative route is 45 minutes longer. All buses arrive in Rome at the Tiburtina bus station on the Piazzale Mazzoni in eastern Rome and connect with the rest of the city by Metro.
Train service between the two cities is excellent, with trains running nearly every half hour from early morning to late at night. Passengers can choose between the Trenitalia and the Italo rail lines and reach Rome by express in just 1 hour 20 minutes, or by 4 hours 30 minutes on a regular train. Travellers can choose to end their journey at either Rome's Tiburtina or Termini stations however all routes depart from Florence at Firenze Santa Maria Novella.
AliItalia offers seven direct flights each day from Pisa and Firenze airports and arriving at Roma Fiumicino. Travel time between the two cities is just 3 hours 16 minutes.