The cheapest and fastest buses from Manchester Piccadilly (MAN) to Southampton
Cheapest price
€16
Average price
€16
Fastest journey
8 h 15 m
Average duration
8 h 15 m
Buses per day
1
Distance
292 km
The best way to find a cheap bus ticket from Manchester Piccadilly (MAN) to Southampton is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Manchester Piccadilly (MAN) to Southampton will cost around €16 if you buy it on the day, but the cheapest tickets can be found for only €16.
Of the 1 buses that leave Manchester Piccadilly (MAN) for Southampton on Sat, Mar 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Mar 21 the direct buses cover the 292 km distance in an average of 8 h 15 m but if you time it right, some buses will get you there in just 8 h 15 m .
On Sat, Mar 21 the slowest buses will take 8 h 15 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.


Travel Information
Compare train, bus, and flight for Manchester Piccadilly (MAN) to Southampton
Omio recommends booking the train as it is the most popular option from Manchester Piccadilly (MAN) to Southampton among Omio's users. If you are prioritising price take the bus with prices starting from €16. For those with little time consider booking a flight which can get you there in 1h 5m. The ticket price range depends on the travel mode: a bus costs an average of €16, and a flight costs an average of €71.
Distance: 292 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€36 Average price Cheapest | €61 Average price | €121 Average price |
7h 37m Average total duration 7h 7m Onboard + 30m Additional time* | 4h 42m Average total duration 4h 12m Onboard + 30m Additional time* | 4h 5m Average total duration Fastest 1h 5m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Manchester Piccadilly (MAN) to Southampton bus times
The table below shows live departures for Manchester Piccadilly (MAN) to Southampton buses for today, Friday, March 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:45 PM Manchester Piccadilly (MAN) | 8h45 | 1:30 AM Southampton | 0 transfersDirect | |
![]() | 7:15 PM Manchester Piccadilly (MAN) | 7h45 | 3:00 AM Southampton | 0 transfersDirect | |
| Saturday, March 21 | |||||
![]() | 6:35 AM Manchester Piccadilly (MAN) | 8h15 | 2:50 PM Southampton | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Manchester Piccadilly (MAN) to Southampton by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 21
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Why should you book Manchester Piccadilly (MAN) to Southampton buses with Omio?
Why book with Omio vs National Express?
- Compare with other providers: On Omio, you can not only buy tickets for National Express, but also compare tickets for the likes of Megabus to find the best option for your trip from Manchester Piccadilly (MAN) to Southampton.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare National Express with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Manchester Piccadilly (MAN) to Southampton.
Why book with Omio over Wanderu?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Megabus to find the best option for your trip from Manchester Piccadilly (MAN) to Southampton.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Manchester Piccadilly (MAN) to Southampton.
Journey information
Overview: Bus from Manchester Piccadilly (MAN) to Southampton
Buses from Manchester Piccadilly (MAN) to Southampton run on average 11 times per day, taking around 7h 7m. Cheap bus tickets for this journey start at €16 if you book in advance.
The earliest bus runs at 05:15, the last at 23:55. The fastest bus covers the 292 km distance in 7h 30m.
Distance 292 km |
Average bus duration 7h 7m |
Cheapest ticket price €16 |
Buses per day 11 |
Fastest bus 7h 30m |
First bus 05:15 |
Last bus 23:55 |
Bus providers: National Express, Megabus from Manchester Piccadilly (MAN) to SouthamptonYou can travel by bus between Manchester Piccadilly (MAN) to Southampton with National Express, Megabus for as low as €16. When you search for schedules and tickets, Omio will show you the best journey
National Express
Megabus
FAQs: Bus from Manchester Piccadilly (MAN) to Southampton
Find answers to the most common questions about traveling from Manchester Piccadilly (MAN) to Southampton by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Southampton, this guide helps you travel smarter and with confidence.

- Megabus
- Megabus is ADA-compliant and provides assistance to customers with disabilities, including those using wheelchairs or mobility scooters, and those with service animals.
- National Express
- Assistance
- Priority seating
- Accessible toilets.
- Megabus
- Megabus reservations cannot be canceled or refunded, but they can be traded in for another journey up to 3 hours before your original scheduled departure for a fee.
- National Express
- You can cancel your ticket up to 24 hours before departure for a refund minus a cancellation fee. Changes can be up to 24 hours before departure for a fee.
- Megabus
- One piece of luggage is included per passenger reservation. For guidance, a piece of luggage must not exceed 62 inches (length + width + height) and should not weigh more than 50 pounds (23kg).
- National Express
- Two medium-sized suitcases up to 20kg each and one small piece of hand luggage.
- Megabus
- Additional luggage can be purchased by buying an additional travel ticket in advance or by adding up to two additional pieces when booking for a fee.
- National Express
- 10€ per additional bag.
popular bus stations
Popular bus stations from Manchester Piccadilly (MAN) to Southampton
- 06:00-22:00
- Free Wi-Fi
- Café Express (in the station)
- Sandwich Bar (in the station).
- Available outside the station.
- Elevators, ramps
- Available near the entrance.
- Bus: U1, U2, U6, X4 Train: South Western Railway
Most popular bus connections from Manchester Piccadilly (MAN)
More options for your journey from Manchester Piccadilly (MAN) to Southampton
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