The cheapest and fastest trains from St. Louis, MO to Chicago, IL
Cheapest price
€85
Average price
€169
Fastest journey
4 h 55 m
Average duration
5 h 8 m
Trains per day
7
Distance
419 km
The best way to find a cheap train ticket from St. Louis, MO to Chicago, IL is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from St. Louis, MO to Chicago, IL will cost around €169 if you buy it on the day, but the cheapest tickets can be found for only €85.
Of the 7 trains that leave St. Louis, MO for Chicago, IL on Mon, Dec 22, 6 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Dec 22 the direct trains cover the 419 km distance in an average of 5 h 8 m but if you time it right, some trains will get you there in just 4 h 55 m .
On Mon, Dec 22 the slowest trains will take 5 h 34 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
318 Lincoln Service Missouri River Runner
300 Lincoln Service
306 Lincoln Service
302 Lincoln Service
22 Texas Eagle
300 Lincoln Service
306 Lincoln Service
318 Lincoln Service Missouri River Runner
302 Lincoln Service
22 Texas EagleTravel Information
Compare train, bus, and flight for St. Louis, MO to Chicago, IL
Omio recommends booking the train as it is the most popular option from St. Louis, MO to Chicago, IL among Omio's users. If you are prioritising price take the bus with prices starting from €28. For those with little time consider booking a flight which can get you there in 1h 21m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €28, and a flight costs an average of €253.
Distance: 419 km
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€45 Average price | €45 Average price Cheapest | €316 Average price |
5h 40m Average total duration 5h 10m Onboard + 30m Additional time* | 6h 50m Average total duration 6h 20m Onboard + 30m Additional time* | 4h 21m Average total duration Fastest 1h 21m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.0kg CO2 emissions | 1.3 - 2.5kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
St. Louis, MO to Chicago, IL train times
The table below shows live departures for St. Louis, MO to Chicago, IL trains for today, Sunday, December 21. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
300 Lincoln Service | 10:30 AM St. Louis Station, St. Louis, MO | 4h55 | 3:25 PM Chicago Union Station, Chicago, IL | 0 transfersDirect | |
22 Texas Eagle | 2:10 PM St. Louis Station, St. Louis, MO | 5h34 | 7:44 PM Chicago Union Station, Chicago, IL | 0 transfersDirect | |
318 Lincoln Service Missouri River Runner | 8:55 PM St. Louis Station, St. Louis, MO | 5h05 | 2:00 AM Chicago Union Station, Chicago, IL | 0 transfersDirect | |
306 Lincoln Service | 11:40 PM St. Louis Station, St. Louis, MO | 5h03 | 4:43 AM Chicago Union Station, Chicago, IL | 0 transfersDirect | |
| Monday, December 22 | |||||
8359 AMTRAK · 58 City Of New Orleans | 5:00 AM St. Louis Station, St. Louis, MO | 10h15 | 3:15 PM Chicago Union Station, Chicago, IL | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets St. Louis, MO to Chicago, IL by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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How far in advance should I book train tickets from St. Louis, MO to Chicago, IL?
Journey information
Overview: Train from St. Louis, MO to Chicago, IL
Trains from St. Louis, MO to Chicago, IL run on average 5 times per day, taking around 5h 10m. Cheap train tickets for this journey start at €29 but you can travel from only €28 by bus.
There are 5 trains per day. The earliest train runs at 04:30, the last at 23:45. The fastest train covers the 419 km distance in 4h 11m.
Distance 419 km |
Average train duration 5h 10m |
Cheapest ticket price €29 |
Trains per day 5 |
Direct trains 5 |
Fastest train 4h 11m |
First train 04:30 |
Last train 23:45 |
Train companies: Amtrak from St. Louis, MO to Chicago, IL trainsAmtrak trains will get you between St. Louis, MO and Chicago, IL from €28. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Amtrak
FAQs: Trains from St. Louis, MO to Chicago, IL
Find answers to the most common questions about traveling from St. Louis, MO to Chicago, IL by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Chicago, IL, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from St. Louis, MO to Chicago, IL
- 5:30 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available on-site with both short-term and long-term options.
- Landry's Seafood House
- The Station Grille
- Outside the main entrance.
- Ramps, restrooms.
- $1
- St. Louis Union Station Hotel, Curio Collection by Hilton
- Courtyard St. Louis Downtown West
- Drury Inn St. Louis at Union Station
- Located in the main hall
- Avis
- Enterprise
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for Amtrak and regional trains
- Hall 2: MetroLink connections
- MetroLink: Red Line, Blue Line
- Bus: Several lines available including 40, 94, 97
- 5:00 AM - 12:00 AM Monday - Sunday
- Free
- The car park is open 7 days a week from 5:00 a.m. to 12:00 a.m. Departures can be made outside of opening hours. Access via Canal Street.
- The Chicago Firehouse Restaurant
- Lou Mitchell's
- Outside the main entrance.
- Elevators, ramps, restrooms.
- $1
- The Kimpton Gray Hotel
- JW Marriott Chicago
- W Chicago - City Center
- Located in the main hall
- Located in the main hall
- Avis
- Budget
- Enterprise
- Located in the main hall
- Free
- Hall 1: main entrance, Amtrak services
- Hall 2: Metra services
- Hall 3: food court and retail shops
- Bus: Several lines available
- CTA: Blue Line, Pink Line
More options for your journey from St. Louis, MO to Chicago, IL
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