Travel Information
Compare train, bus, and flight for Avignon to Lyon
Omio recommends booking the train as it is the most popular option from Avignon to Lyon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €25 For those with little time, consider booking a train, which has an average total journey time of 1h 59m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.2kg. Average ticket prices depend on the travel mode: a bus costs an average of €25, while a flight costs an average of €283.
Distance: 200 km
Compare train with
Most popular Train | Bus | Flight | Driving |
|---|---|---|---|
€52 Average price | €25 Average price Cheapest | €283 Average price | €61 Average price (fuel + tolls) |
1h 59m Average total duration Fastest 1h 29m Onboard + 30m Additional time* | 3h 34m Average total duration 3h 4m Onboard + 30m Additional time* | 4h 42m Average total duration 2h 42m Onboard + 2h 0m Additional time* | 2h 29m Average total duration (door-to-door) |
0.1 - 0.2kg CO2 emissions Lowest | 0.2 - 0.5kg CO2 emissions | 0.6 - 1.2kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Avignon to Lyon
Compare the available ways to get from Avignon to Lyon, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Avignon to Lyon:
A bus is €27 less than a train for this route with tickets for a train from Avignon to Lyon costing on average €52.
A bus is €259 less than a flight for this route with tickets for a flight from Avignon to Lyon costing on average €283.
Other travel options to Lyon take longer:
Bus takes on average 3h 34m.
Flight takes on average 4h 42m.
Travel optionsfrom Avignon to Lyon
How to get from Avignon to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Avignon to Lyon is by taking a bus because it’s the best combination of price and speed.
FlixBus3:35 PM 3h05 Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) 6:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) €13 1 One-way 0 transfers
Cheapest
FlixBus3:35 PM 3h05 Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) 6:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) €13 1 One-way 0 transfers
Fastest
FRECCIAROSSA 1000 61083:58 PM 0h50 Avignon TGV 4:48 PM Lyon Saint-Exupéry TGV €68 1 One-way 0 transfers
Other options
68528:50 PM 1h10 Avignon TGV 10:00 PM Lyon Part Dieu €40 1 One-way 0 transfers
8861806:44 AM 2h29 Avignon Centre 9:13 AM Lyon-Jean-Macé €44 1 One-way 0 transfers
8861745:41 AM 2h31 Avignon Centre 8:12 AM Lyon-Jean-Macé €44 1 One-way 0 transfers
FlixBus1:00 PM 3h05 Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) 4:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) €13 1 One-way 0 transfers
FlixBus11:50 AM 3h15 Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) 3:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) €13 1 One-way 0 transfers
580810:20 PM 2h30 Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) 12:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) €14 1 One-way 0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
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FAQs: Travel from Avignon to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Avignon to Lyon.

This is compared to other travel options from Avignon to Lyon:
A bus is €27 less than a train for this route with tickets for a train from Avignon to Lyon costing on average €52.
A bus is €259 less than a flight for this route with tickets for a flight from Avignon to Lyon costing on average €283.
Other travel options to Lyon take longer:
Bus takes on average 3h 34m.
Flight takes on average 4h 42m.
- Around 31 trains per day.
- Around 16 flights per day.
- Around 4 buses per day.
However, we recommend checking specific travel dates for your route between Avignon and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Marseille Provence Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Avignon Centre and arrive in Lyon Part Dieu.
- Buses mostly depart from Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
- Travel with FlixBus, BlaBlaCar Bus, Alsa, Infobus, Internorte to go to Lyon by bus.
- Travel with SNCF | TGV INOUI, TER, Trenitalia, SNCF TER | Operated by SNCF Voyageurs 1187, SNCF | TGV Lyria, ZOU! to go to Lyon by train.
- Travel with Air France to go to Lyon by flight.
- 4 direct buses per day with FlixBus, BlaBlaCar Bus, Alsa, Internorte.
- 21 direct trains per day with SNCF | TGV INOUI, TER, Trenitalia, SNCF TER | Operated by SNCF Voyageurs 1187, SNCF | TGV Lyria.
Travelling from Avignon to Lyon: related information
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