Travel Information
Compare train, bus, and flight for Avignon to Lyon
Omio recommends booking the train as it is the most popular option from Avignon to Lyon among Omio's users. If you are prioritising price, take the train, with an average ticket price of €37 For those with little time, consider booking a train, which has an average total journey time of 2h 12m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.2kg. Average ticket prices depend on the travel mode: a train costs an average of €37, while a bus costs an average of €45.
Distance: 200 km
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
€37 Average price Cheapest | €45 Average price | €61 Average price (fuel + tolls) |
2h 12m Average total duration Fastest 1h 42m Onboard + 30m Additional time* | 3h 14m Average total duration 2h 44m Onboard + 30m Additional time* | 2h 29m Average total duration (door-to-door) |
0.1 - 0.2kg CO2 emissions Lowest | 0.2 - 0.5kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Avignon to Lyon:
A bus is €26 less than a train for this route with tickets for a train from Avignon to Lyon costing on average €50.
A bus is €315 less than a flight for this route with tickets for a flight from Avignon to Lyon costing on average €339.
Other travel options to Lyon take longer:
Bus takes on average 3h 35m.
Flight takes on average 4h 38m.
Travel optionsfrom Avignon to Lyon
How to get from Avignon to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Avignon to Lyon is by taking a bus because it’s the best combination of price and speed.
580810:20 PM2h30Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)12:50 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€141One-way0 transfers
Cheapest
580810:20 PM2h30Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)12:50 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€141One-way0 transfers
Fastest
FRECCIAROSSA 1000 61083:58 PM0h50Avignon TGV4:48 PMLyon Saint-Exupéry TGV€491One-way0 transfers
Other options
FRECCIAROSSA 1000 61407:32 AM1h08Avignon TGV8:40 AMLyon Part Dieu€331One-way0 transfers
FRECCIAROSSA 1000 610410:47 AM0h52Avignon TGV11:39 AMLyon Saint-Exupéry TGV€411One-way0 transfers
FRECCIAROSSA 1000 61487:41 PM0h52Avignon TGV8:33 PMLyon Saint-Exupéry TGV€411One-way0 transfers
FlixBus7:00 PM2h45Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)9:45 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€201One-way0 transfers
FlixBus3:35 PM3h05Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)6:40 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€211One-way0 transfers
FlixBus12:15 AM2h40Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle)2:55 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€231One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Avignon to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Avignon to Lyon.

This is compared to other travel options from Avignon to Lyon:
A train is €9 less than a bus for this route with tickets for a bus from Avignon to Lyon costing on average €45.
A train is €86 less than a flight for this route with tickets for a flight from Avignon to Lyon costing on average €122.
Other travel options to Lyon take longer:
Bus takes on average 3h 14m.
Flight takes on average 3h 34m.
- Around 28 trains per day.
- Around 13 flights per day.
- Around 9 buses per day.
However, we recommend checking specific travel dates for your route between Avignon and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Marseille Provence Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Avignon TGV and arrive in Lyon Part Dieu.
- Buses mostly depart from Le Pontet, Avignon Gare de Bus (Ave. Charles de Gaulle) and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
- Travel with SNCF | TGV Lyria, SNCF TER | Operated by SNCF Voyageurs 1187, TER, Trenitalia, ZOU!, SNCF | TGV INOUI to go to Lyon by train.
- Travel with Alsa, Infobus, BlaBlaCar Bus, Internorte, FlixBus to go to Lyon by bus.
- Travel with Air France to go to Lyon by flight.
- 19 direct trains per day with SNCF | TGV Lyria, SNCF TER | Operated by SNCF Voyageurs 1187, TER, Trenitalia, SNCF | TGV INOUI.
- 9 direct buses per day with Alsa, BlaBlaCar Bus, Internorte, FlixBus.
Travelling from Avignon to Lyon: related information
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