Travel Information
Compare bus, train, and flight for Heidelberg to Prague
Omio recommends booking the bus as it is the most popular option from Heidelberg to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €39 For those with little time, consider booking a flight, which has an average total journey time of 4h 44m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.1 - 0.4kg. Average ticket prices depend on the travel mode: a bus costs an average of €39, while a flight costs an average of €338.
Distance: 418 km
Compare bus with
Most popular Bus | Train | Flight | Driving |
|---|---|---|---|
€39 Average price Cheapest | €110 Average price | €338 Average price | €91 Average price (fuel + tolls) |
7h 59m Average total duration 7h 29m Onboard + 30m Additional time* | 8h 27m Average total duration 7h 57m Onboard + 30m Additional time* | 4h 44m Average total duration Fastest 2h 44m Onboard + 2h 0m Additional time* | 5h 36m Average total duration (door-to-door) |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | 1.3 - 2.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare ways to travel from Heidelberg to Prague
Compare the available ways to get from Heidelberg to Prague, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Heidelberg to Prague:
A bus is €71 less than a train for this route with tickets for a train from Heidelberg to Prague costing on average €110.
A bus is €299 less than a flight for this route with tickets for a flight from Heidelberg to Prague costing on average €338.
Other travel options to Prague take longer:
Bus takes on average 7h 59m.
Train takes on average 8h 27m.
Travel optionsfrom Heidelberg to Prague
How to get from Heidelberg to Prague by train, bus or flight.
Our recommendation
The best way to travel from Heidelberg to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBus5:50 AM6h55Heidelberg, Hauptbahnhof12:45 PMPraha, Na Knížecí€341One-way0 transfers
Cheapest
FlixBus5:50 AM6h55Heidelberg, Hauptbahnhof12:45 PMPraha, Na Knížecí€341One-way0 transfers
Fastest
DE44073:00 PM1h00Frankfurt am Main Airport4:00 PMPrague Vaclav Havel Airport€1571One-way0 transfers
Other options
IC 1648 · 88617 · 3569 · Bus RE259:36 AM8h45Heidelberg Hbf6:21 PMPrague hlavní nádraží€431One-way4 transfers
ICE 217 · 88619 · 3573 · Bus RE2512:06 PM8h15Heidelberg Hbf8:21 PMPrague hlavní nádraží€661One-way4 transfers
ICE 211 · Bus RE25 · EX 363+
3631:13 PM9h09Heidelberg Hbf10:22 PMPrague hlavní nádraží€701One-way3 transfers
FlixBus5:50 AM7h15Heidelberg, Hauptbahnhof1:05 PMPraha, ÚAN Florenc€341One-way0 transfers
FlixBus+
FlixTrain5:06 PM9h44Heidelberg Hbf2:50 AMPrague, Central Train Station€431One-way1 transfer
FlixBus4:05 PM6h50Heidelberg, Hauptbahnhof10:55 PMPraha, Na Knížecí€461One-way0 transfers
DE440910:00 AM1h00Frankfurt am Main Airport11:00 AMPrague Vaclav Havel Airport€1571One-way0 transfers
ICE 994 · 4654 · ICE 316+
DE44077:18 AM8h42Heidelberg Hbf4:00 PMPrague Vaclav Havel Airport€1841One-way3 transfers
S3 · ICE 614+
DE44078:13 AM7h47Heidelberg Hbf4:00 PMPrague Vaclav Havel Airport€1901One-way2 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Heidelberg to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Heidelberg to Prague.

This is compared to other travel options from Heidelberg to Prague:
A bus is €71 less than a train for this route with tickets for a train from Heidelberg to Prague costing on average €110.
A bus is €299 less than a flight for this route with tickets for a flight from Heidelberg to Prague costing on average €338.
Other travel options to Prague take longer:
Bus takes on average 7h 59m.
Train takes on average 8h 27m.
- Around 65 flights per day.
- Around 13 trains per day.
- Around 8 buses per day.
However, we recommend checking specific travel dates for your route between Heidelberg and Prague as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Frankfurt am Main Airport and arrive in Prague Vaclav Havel Airport.
- Trains mostly depart from Heidelberg Hbf and arrive in Prague hlavní nádraží.
- Buses mostly depart from Heidelberg, Hauptbahnhof and arrive in Praha, ÚAN Florenc.
- Travel with FlixBus, BlaBlaCar Bus, KLR to go to Prague by bus.
- Travel with alex-Länderbahn und Vogtlandbahn-GmbH, Deutsche Bahn, České dráhy to go to Prague by train.
- Travel with Lufthansa, Condor Flugdienst, Swiss, Lufthansa Cityline, KLM Cityhopper, Brussels Airlines, Qatar Airways, braathens regional aviation, Air Baltic, Helvetic Airways, Lot Polish Airlines, British Airways, Edelweiss Air, CitizenPlane, Eurowings, KLM, Air Dolomiti, Austrian Airlines, Turkish Airlines, TAP Portugal to go to Prague by flight.
- 4 direct buses per day with FlixBus, BlaBlaCar Bus, KLR.
- 8 direct flights per day with Lufthansa, Condor Flugdienst, Air Dolomiti.
Travelling from Heidelberg to Prague: related information
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