Travel Information
Compare train and bus for Pisa to Milan
Omio recommends booking the train as it is the most popular option from Pisa to Milan among Omio's users. If you are prioritising price take the train with prices starting from €17. For those with little time consider booking a train which can get you there in 3h 48m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a train costs an average of €17, and a bus costs an average of €15.
Distance: 217 km
Compare train with
Most popular Train | Bus |
|---|---|
€28 Average price Cheapest | €28 Average price |
4h 18m Average total duration Fastest 3h 48m Onboard + 30m Additional time* | 4h 44m Average total duration 4h 14m Onboard + 30m Additional time* |
0.1 - 0.2kg CO2 emissions Lowest | 0.2 - 0.5kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Pisa to Milan
How to get from Pisa to Milan by train, bus or flight.
Our recommendation
The best way to travel from Pisa to Milan is by taking a train because it’s the best combination of price and speed.
Regionale 22946:00 AM4h16Pisa Centrale10:16 AMMilan Rogoredo€241One-way0 transfers
Cheapest
Regionale 22946:00 AM4h16Pisa Centrale10:16 AMMilan Rogoredo€241One-way0 transfers
Fastest
Regionale 4028+
817611:09 AM3h11Pisa Centrale2:20 PMMilan Centrale€691One-way1 transfer
Other options
Regionale 22966:57 PM4h25Pisa Centrale11:22 PMMilan Centrale€241One-way0 transfers
Regionale 22946:00 AM4h50Pisa Centrale10:50 AMMilan Porta Garibaldi€241One-way0 transfers
Regionale 18381 · Regionale 19258 · Regionale Veloce TTPER 24865:09 PM5h36Pisa Centrale10:45 PMMilan Centrale€261One-way2 transfers
FlixBus9:40 AM6h45Pisa, Via delle Fiamme Gialle (Park Pietrasantina)4:25 PMMilano, Autostazione Lampugnano€291One-way0 transfers
FlixBus · FlixBus5:45 AM9h45Pisa, Via delle Fiamme Gialle (Park Pietrasantina)3:30 PMMilano, Milan Linate Airport€361One-way1 transfer
FlixBus · FlixBus4:45 AM7h00Pisa, Via delle Fiamme Gialle (Park Pietrasantina)11:45 AMMilano, San Donato - Settore B (Viale Giuseppe Impastato)€401One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Pisa to Milan
Travel to Milan easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Pisa to Milan.

This is compared to other travel options from Pisa to Milan:
A train is €0.36 less than a bus for this route with tickets for a bus from Pisa to Milan costing on average €28.
Other travel options to Milan take longer:
Bus takes on average 4h 14m.
- Around 41 trains per day.
- Around 10 buses per day.
However, we recommend checking specific travel dates for your route between Pisa and Milan as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Pisa Centrale and arrive in Milan Centrale.
- Buses mostly depart from Pisa, Via delle Fiamme Gialle (Park Pietrasantina) and arrive in Milano, Autostazione Lampugnano.
- Travel with Italo, Intercity, Regionale, Frecciabianca, Frecciarossa, Intercity Notte, Frecciargento to go to Milan by train.
- Travel with FlixBus, BlaBlaCar, Itabus, Autostradale to go to Milan by bus.
- 8 direct trains per day with Intercity, Frecciabianca, Frecciarossa.
- 5 direct buses per day with FlixBus, BlaBlaCar, Itabus, Autostradale.
Travelling from Pisa to Milan: related information
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