Travel Information
Compare train, bus, and flight for Toulouse to Lyon
Omio recommends booking the bus as it is the most popular option from Toulouse to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €18. For those with little time consider booking a flight which can get you there in 2h 52m. The ticket price range depends on the travel mode: a bus costs an average of €18, and a flight costs an average of €51.
Distance: 359 km
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
€32 Average price Cheapest | €78 Average price | €117 Average price |
7h 12m Average total duration 6h 42m Onboard + 30m Additional time* | 5h 48m Average total duration 5h 18m Onboard + 30m Additional time* | 5h 52m Average total duration Fastest 2h 52m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Travel optionsfrom Toulouse to Lyon
How to get from Toulouse to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Toulouse to Lyon is by taking a bus because it’s the best combination of price and speed.
FlixBus6:40 AM6h50Toulouse, Gare routière Pierre Semard (Matabiau)1:30 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€351One-way0 transfers
Cheapest
FlixBus6:40 AM6h50Toulouse, Gare routière Pierre Semard (Matabiau)1:30 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€351One-way0 transfers
Fastest
EC43265:05 PM1h00Toulouse Blagnac Airport6:05 PMLyon Saint Exupery Airport€1231One-way0 transfers
Other options
68755:41 PM3h57Gare de Toulouse-Matabiau9:38 PMLyon Part Dieu€531One-way0 transfers
68717:39 AM4h09Gare de Toulouse-Matabiau11:48 AMLyon Part Dieu€621One-way0 transfers
68733:44 PM4h06Gare de Toulouse-Matabiau7:50 PMLyon Part Dieu€711One-way0 transfers
FlixBus10:15 PM9h30Toulouse, Gare routière Pierre Semard (Matabiau)7:45 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€351One-way0 transfers
3141 · 31546:20 PM9h45Toulouse, Gare routière Pierre Semard (Matabiau)4:05 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€441One-way1 transfer
50591 · 58082:55 PM9h55Toulouse, Gare routière Pierre Semard (Matabiau)12:50 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€451One-way1 transfer
AF7407+
AF736811:45 AM6h25Toulouse Blagnac Airport6:10 PMLyon Saint Exupery Airport€1921One-way1 transfer
AF7405+
AF736810:30 AM7h40Toulouse Blagnac Airport6:10 PMLyon Saint Exupery Airport€1921One-way1 transfer
AF7407 · AF737011:45 AM9h40Toulouse Blagnac Airport9:25 PMLyon Saint Exupery Airport€1921One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Toulouse to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Toulouse to Lyon.

This is compared to other travel options from Toulouse to Lyon:
A bus is €46 less than a train for this route with tickets for a train from Toulouse to Lyon costing on average €78.
A bus is €85 less than a flight for this route with tickets for a flight from Toulouse to Lyon costing on average €117.
Other travel options to Lyon take longer:
Train takes on average 5h 18m.
Bus takes on average 6h 42m.
- Around 14 flights per day.
- Around 13 buses per day.
- Around 6 trains per day.
However, we recommend checking specific travel dates for your route between Toulouse and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Toulouse Blagnac Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Gare de Toulouse-Matabiau and arrive in Lyon Part Dieu.
- Buses mostly depart from Toulouse, Gare routière Pierre Semard (Matabiau) and arrive in Lyon, Perrache Bus Station.
- Travel with easyJet, Air France to go to Lyon by flight.
- Travel with BlaBlaCar Bus, FlixBus, Alsa, Internorte, BlaBlaCar to go to Lyon by bus.
- Travel with SNCF | TGV INOUI, SNCF | Intercités, SNCF TER | Operated by SNCF Voyageurs 1187, TGV, SNCF | Intercités de nuit, TER liO | Operated by SNCF Voyageurs 1187 to go to Lyon by train.
- 1 direct flights per day with easyJet, Air France.
- 9 direct buses per day with BlaBlaCar Bus, FlixBus, Alsa, Internorte, BlaBlaCar.
- 2 direct trains per day with SNCF | TGV INOUI.
Travelling from Toulouse to Lyon: related information
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