The cheapest and fastest buses from Rome Termini to Pisa Centrale
Cheapest price
€16
Average price
€25
Fastest journey
3 h 50 m
Average duration
4 h 31 m
Buses per day
10
Distance
264 km
The best way to find a cheap bus ticket from Rome Termini to Pisa Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome Termini to Pisa Centrale will cost around €25 if you buy it on the day, but the cheapest tickets can be found for only €16.
Of the 10 buses that leave Rome Termini for Pisa Centrale on Wed, Apr 01, 7 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Apr 01 the direct buses cover the 264 km distance in an average of 4 h 31 m but if you time it right, some buses will get you there in just 3 h 50 m .
On Wed, Apr 01 the slowest buses will take 5 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
2061:50 PM5h45Roma, Autostazione Tiburtina7:35 PMPisa, Via delle Fiamme Gialle (Park Pietrasantina)€161One-way0 transfers
2061:50 PM5h10Roma, Autostazione Tiburtina7:00 PMLucca, Stazione FS€161One-way0 transfers
FlixBus6:50 PM4h35Roma, Autostazione Tiburtina11:25 PMPisa, Aeroporto Parcheggio Aurelia€181One-way0 transfers
2:30 PM5h00Rome Termini7:30 PMPisa Centrale€211One-way0 transfers
12:00 PM3h50Rome Termini3:50 PMPisa Centrale€221One-way0 transfers
12:00 PM3h50Rome Termini3:50 PMPisa Centrale€221One-way0 transfers
8:20 AM4h00Rome Termini12:20 PMPisa Centrale€301One-way0 transfers
FlixBus6:50 PM4h35Roma, Autostazione Tiburtina11:25 PMPisa, Aeroporto Parcheggio Aurelia€181One-way0 transfers
2:30 PM5h00Rome Termini7:30 PMPisa Centrale€211One-way0 transfers
2061:50 PM5h10Roma, Autostazione Tiburtina7:00 PMLucca, Stazione FS€161One-way0 transfers
Travel Information
Compare train and bus for Rome Termini to Pisa Centrale
Omio recommends booking the train as it is the most popular option from Rome Termini to Pisa Centrale among Omio's users. If you are prioritising price take the bus with prices starting from €12. For those with little time consider booking a train which can get you there in 3h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a bus costs an average of €12, and a train costs an average of €21.
Distance: 264 km
Compare bus with
| Bus | Most popular Train |
|---|---|
€17 Average price Cheapest | €30 Average price |
5h 26m Average total duration 4h 56m Onboard + 30m Additional time* | 3h 49m Average total duration Fastest 3h 19m Onboard + 30m Additional time* |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.2kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Rome Termini to Pisa Centrale bus times
The table below shows live departures for Rome Termini to Pisa Centrale buses for today, Tuesday, March 31. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 10:10 PM Roma, Autostazione Tiburtina | 5h30 | 3:40 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 0 transfersDirect | |
![]() | 10:50 PM Rome Termini | 13h40 | 12:30 PM Pisa Centrale | 0 transfersDirect | |
| Wednesday, April 1 | |||||
FlixBus · FlixBus | 5:55 AM Roma, Autostazione Tiburtina | 5h35 | 11:30 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 1 transfer | |
FlixBus · FlixBus | 9:50 AM Roma, Autostazione (Metro Anagnina) | 6h15 | 4:05 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 1 transfer | |
FlixBus · FlixBus | 10:20 AM Roma, Autostazione Tiburtina | 5h45 | 4:05 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 1 transfer | |
206 | 11:50 AM Roma, Autostazione Tiburtina | 5h45 | 5:35 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 0 transfersDirect | |
206 | 11:50 AM Roma, Autostazione Tiburtina | 5h10 | 5:00 PM Lucca, Stazione FS | 0 transfersDirect | |
FlixBus | 4:50 PM Roma, Autostazione Tiburtina | 4h35 | 9:25 PM Pisa, Aeroporto Parcheggio Aurelia | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome Termini to Pisa Centrale by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 01
Apr 02
Apr 03
Apr 04
Apr 05
Apr 06
Apr 07
Apr 08
Apr 09
Apr 10
Apr 11
Apr 12
Apr 13
Apr 14
Apr 15
Apr 16
Apr 17
Apr 18
Apr 19
Apr 20
Apr 21
Why should you book Rome Termini to Pisa Centrale buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Marino Autolinee or Itabus to find the best option for your trip from Rome Termini to Pisa Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Rome Termini to Pisa Centrale.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Marino Autolinee or Itabus to find the best option for your trip from Rome Termini to Pisa Centrale.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Rome Termini to Pisa Centrale.
Journey information
Overview: Bus from Rome Termini to Pisa Centrale
Buses from Rome Termini to Pisa Centrale run on average 9 times per day, taking around 4h 56m. Cheap bus tickets for this journey start at €12 if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:30, the last at 22:50. The fastest bus covers the 264 km distance in 4h 35m.
Distance 264 km |
Average bus duration 4h 56m |
Cheapest ticket price €12 |
Buses per day 9 |
Direct buses 6 |
Fastest bus 4h 35m |
First bus 12:30 AM |
Last bus 10:50 PM |
Bus providers: FlixBus, Marino Autolinee, BlaBlaCar, Itabus from Rome Termini to Pisa CentraleYou can travel by bus between Rome Termini to Pisa Centrale with FlixBus, Marino Autolinee, BlaBlaCar, Itabus for as low as €12. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Marino Autolinee
Itabus
BlaBlaCar
FAQs: Bus from Rome Termini to Pisa Centrale
Find answers to the most common questions about traveling from Rome Termini to Pisa Centrale by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Pisa Centrale, this guide helps you travel smarter and with confidence.

- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
Most popular bus connections from Rome Termini
More options for your journey from Rome Termini to Pisa Centrale
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