The cheapest and fastest buses from Rome Termini to Milan Centrale
Cheapest price
€10
Average price
€26
Fastest journey
7 h 30 m
Average duration
7 h 44 m
Buses per day
37
Distance
479 km
The best way to find a cheap bus ticket from Rome Termini to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome Termini to Milan Centrale will cost around €26 if you buy it on the day, but the cheapest tickets can be found for only €10.
Of the 37 buses that leave Rome Termini for Milan Centrale on Tue, May 26, 30 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, May 26 the direct buses cover the 479 km distance in an average of 7 h 44 m but if you time it right, some buses will get you there in just 7 h 30 m .
On Tue, May 26 the slowest buses will take 8 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
21268:00 AM8h40Roma, Autostazione Tiburtina4:40 PMMilano, Autostazione Lampugnano€101One-way0 transfers
FlixBus4:35 PM8h30Roma, Autostazione Tiburtina1:05 AMMilano, Autostazione Lampugnano€101One-way0 transfers
FlixBus10:10 AM8h25Roma, Autostazione Tiburtina6:35 PMMilano, Autostazione Lampugnano€101One-way0 transfers
FlixBus6:50 PM9h40Roma, Autostazione Tiburtina4:30 AMAssago, Viale Milanofiori (Assago M2)€111One-way0 transfers
FlixBus6:50 PM11h40Roma, Autostazione Tiburtina6:30 AMSesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria)€111One-way0 transfers
FlixBus9:45 PM7h30Roma, Autostazione Tiburtina5:15 AMMilano, San Donato - Settore B (Viale Giuseppe Impastato)€341One-way0 transfers
FlixBus2:45 PM7h35Roma, Autostazione Tiburtina10:20 PMMilano, San Donato - Settore B (Viale Giuseppe Impastato)€211One-way0 transfers
34927:00 AM7h45Roma, Autostazione Tiburtina2:45 PMMilano, Autostazione Lampugnano€131One-way0 transfers
FlixBus10:40 AM7h50Roma, Autostazione Tiburtina6:30 PMMilano, San Donato - Settore B (Viale Giuseppe Impastato)€211One-way0 transfers
05411:00 PM8h00Roma, Autostazione Tiburtina7:00 AMMilano, Autostazione Lampugnano€591One-way0 transfers
Travel Information
Compare train, bus, and flight for Rome Termini to Milan Centrale
Omio recommends booking the train as it is the most popular option from Rome Termini to Milan Centrale among Omio's users. If you are prioritising price take the bus with prices starting from €6. For those with little time consider booking a flight which can get you there in 2h 41m. The ticket price range depends on the travel mode: a bus costs an average of €6, and a flight costs an average of €59.
Distance: 479 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€19 Average price Cheapest | €60 Average price | €172 Average price |
7h 49m Average total duration 7h 19m Onboard + 30m Additional time* | 6h 14m Average total duration 5h 44m Onboard + 30m Additional time* | 5h 41m Average total duration Fastest 2h 41m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Rome Termini to Milan Centrale bus times
The table below shows live departures for Rome Termini to Milan Centrale buses for today, Monday, May 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 10:50 PM Rome Termini | 9h25 | 8:15 AM Milan Centrale | 0 transfersDirect | |
| Tuesday, May 26 | |||||
FlixBus · FlixBus | 1:20 AM Roma, Autostazione Tiburtina | 10h50 | 12:10 PM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 1 transfer | |
FlixBus · FlixBus | 1:20 AM Roma, Autostazione Tiburtina | 10h20 | 11:40 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
109 | 5:40 AM Roma, Autostazione Tiburtina | 8h05 | 1:45 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 6:30 AM Roma, Autostazione Tiburtina | 8h05 | 2:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 6:30 AM Roma, Autostazione Tiburtina | 8h50 | 3:20 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
3492 | 7:00 AM Roma, Autostazione Tiburtina | 7h45 | 2:45 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
2126 | 8:00 AM Roma, Autostazione Tiburtina | 8h40 | 4:40 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 8:20 AM Roma, Autostazione Tiburtina | 10h49 | 7:09 PM Cormano, A4 (Cusano Milanino West) | 1 transfer | |
FlixBus | 8:30 AM Roma, Autostazione Tiburtina | 8h00 | 4:30 PM Assago, Viale Milanofiori (Assago M2) | 0 transfersDirect | |
FlixBus | 8:30 AM Roma, Autostazione Tiburtina | 8h40 | 5:10 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 9:25 AM Roma, Autostazione Tiburtina | 8h30 | 5:55 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 10:10 AM Roma, Autostazione Tiburtina | 8h25 | 6:35 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 10:40 AM Roma, Autostazione Tiburtina | 7h50 | 6:30 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 10:40 AM Roma, Autostazione Tiburtina | 8h35 | 7:15 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 11:10 AM Roma, Autostazione (Metro Anagnina) | 10h15 | 9:25 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus | 12:10 PM Roma, Autostazione Tiburtina | 9h30 | 9:40 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 12:10 PM Roma, Autostazione Tiburtina | 9h00 | 9:10 PM Assago, Viale Milanofiori (Assago M2) | 0 transfersDirect | |
FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 9h50 | 10:55 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 9h15 | 10:20 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus | 2:45 PM Roma, Autostazione Tiburtina | 7h35 | 10:20 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 2:45 PM Roma, Autostazione Tiburtina | 8h10 | 10:55 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 4:35 PM Roma, Autostazione Tiburtina | 8h30 | 1:05 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 6:50 PM Roma, Autostazione Tiburtina | 9h40 | 4:30 AM Assago, Viale Milanofiori (Assago M2) | 0 transfersDirect | |
FlixBus | 6:50 PM Roma, Autostazione Tiburtina | 11h40 | 6:30 AM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 0 transfersDirect | |
FlixBus | 8:00 PM Roma, Autostazione Tiburtina | 8h00 | 4:00 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
1101 · 3506 | 9:30 PM Fiumicino, Aeroporto Leonardo de Vinci (T3 Arrivi - Stazione degli autobus) | 11h20 | 8:50 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus | 9:45 PM Roma, Autostazione Tiburtina | 8h10 | 5:55 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 9:45 PM Roma, Autostazione Tiburtina | 7h30 | 5:15 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
3898 | 9:45 PM Roma, Autostazione Tiburtina | 8h25 | 6:10 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 10:45 PM Roma, Autostazione Tiburtina | 8h10 | 6:55 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
3826 | 10:45 PM Roma, Autostazione Tiburtina | 9h05 | 7:50 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
054 | 11:00 PM Roma, Autostazione Tiburtina | 8h00 | 7:00 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
3506 | 11:15 PM Roma, Autostazione Tiburtina | 9h35 | 8:50 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 11:35 PM Roma, Autostazione (Metro Anagnina) | 9h25 | 9:00 AM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 0 transfersDirect | |
FlixBus | 11:35 PM Roma, Autostazione (Metro Anagnina) | 9h55 | 9:30 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 11:50 PM Roma, Autostazione Tiburtina | 9h25 | 9:15 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 11:50 PM Roma, Autostazione Tiburtina | 8h40 | 8:30 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome Termini to Milan Centrale by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Rome Termini to Milan Centrale buses with Omio?
Why book with Omio vs Itabus?
- Compare with other providers: On Omio, you can not only buy tickets for Itabus, but also compare tickets for the likes of FlixBus, Autoservizi Salemi, Marino Autolinee or BlaBlaCar Bus to find the best option for your trip from Rome Termini to Milan Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Itabus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome Termini to Milan Centrale.
Why book with Omio over Checkmybus, Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus, Autoservizi Salemi, Marino Autolinee or BlaBlaCar Bus to find the best option for your trip from Rome Termini to Milan Centrale.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome Termini to Milan Centrale.
Journey information
Overview: Bus from Rome Termini to Milan Centrale
Buses from Rome Termini to Milan Centrale run on average 34 times per day, taking around 7h 19m. Cheap bus tickets for this journey start at €6 if you book in advance.
There are 25 buses per day. The earliest bus runs at 03:40, the last at 22:50. The fastest bus covers the 479 km distance in 8h 5m.
Distance 479 km |
Average bus duration 7h 19m |
Cheapest ticket price €6 |
Buses per day 34 |
Direct buses 25 |
Fastest bus 8h 5m |
First bus 3:40 AM |
Last bus 10:50 PM |
Cheapest Month Dec |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sun |
Bus providers: Itabus, FlixBus, Autoservizi Salemi, Marino Autolinee, BlaBlaCar, BlaBlaCar Bus from Rome Termini to Milan CentraleYou can travel by bus between Rome Termini to Milan Centrale with Itabus, FlixBus, Autoservizi Salemi, Marino Autolinee, BlaBlaCar, BlaBlaCar Bus for as low as €6. When you search for schedules and tickets, Omio will show you the best journey
Itabus
FlixBus
Marino Autolinee
BlaBlaCar Bus
Autoservizi Salemi
BlaBlaCar
FAQs: Bus from Rome Termini to Milan Centrale
Find answers to the most common questions about traveling from Rome Termini to Milan Centrale by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Autoservizi Salemi
- The cancellation policy can vary by ticket class, individual trips, or promotions, so it's best to check the terms during booking.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- Autoservizi Salemi
- Two pieces of luggage: one large suitcase for the hold and one smaller backpack for on-board.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
Most popular bus connections from Rome Termini
More options for your journey from Rome Termini to Milan Centrale
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