The cheapest and fastest buses from Rome to Lucerne
Cheapest price
€58
Average price
€109
Fastest journey
14 h
Average duration
14 h 57 m
Buses per day
5
Distance
662 km
The best way to find a cheap bus ticket from Rome to Lucerne is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Lucerne will cost around €109 if you buy it on the day, but the cheapest tickets can be found for only €58.
It's difficult to get from Rome to Lucerne without transferring at least once.
FlixBus · FlixBus12:10 PM14h00Roma, Autostazione Tiburtina2:10 AMLuzern, Landenburgstrasse (Busparkplatz)€581One-way1 transfer
FlixBus · FlixBus · FlixBus11:10 AM15h00Roma, Autostazione (Metro Anagnina)2:10 AMLuzern, Landenburgstrasse (Busparkplatz)€941One-way2 transfers
FlixBus · FlixBus · FlixBus12:55 PM15h25Roma, Autostazione Tiburtina4:20 AMLuzern, Landenburgstrasse (Busparkplatz)€1231One-way2 transfers
FlixBus · FlixBus · FlixBus1:05 PM15h15Roma, Autostazione (Metro Anagnina)4:20 AMLuzern, Landenburgstrasse (Busparkplatz)€1281One-way2 transfers
FlixBus · FlixBus · FlixBus1:20 AM15h05Roma, Autostazione Tiburtina4:25 PMLuzern, Landenburgstrasse (Busparkplatz)€1381One-way2 transfers
FlixBus · FlixBus12:10 PM14h00Roma, Autostazione Tiburtina2:10 AMLuzern, Landenburgstrasse (Busparkplatz)€581One-way1 transfer
FlixBus · FlixBus · FlixBus11:10 AM15h00Roma, Autostazione (Metro Anagnina)2:10 AMLuzern, Landenburgstrasse (Busparkplatz)€941One-way2 transfers
FlixBus · FlixBus · FlixBus1:20 AM15h05Roma, Autostazione Tiburtina4:25 PMLuzern, Landenburgstrasse (Busparkplatz)€1381One-way2 transfers
FlixBus · FlixBus · FlixBus1:05 PM15h15Roma, Autostazione (Metro Anagnina)4:20 AMLuzern, Landenburgstrasse (Busparkplatz)€1281One-way2 transfers
FlixBus · FlixBus · FlixBus12:55 PM15h25Roma, Autostazione Tiburtina4:20 AMLuzern, Landenburgstrasse (Busparkplatz)€1231One-way2 transfers
Travel Information
Compare bus, train, and flight for Rome to Lucerne
Omio recommends booking the train as it is the most popular option from Rome to Lucerne among Omio's users. If you are prioritising price take the bus with prices starting from €38. For those with little time consider booking a flight which can get you there in 1h 31m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €38, and a flight costs an average of €38.
Distance: 662 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€57 Average price Cheapest | €136 Average price | €152 Average price |
12h 37m Average total duration 12h 7m Onboard + 30m Additional time* | 8h 41m Average total duration 8h 11m Onboard + 30m Additional time* | 4h 31m Average total duration Fastest 1h 31m Onboard + 3h 0m Additional time* |
0.7 - 1.7kg CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest | 2.0 - 4.0kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Rome to Lucerne bus times
The table below shows live departures for Rome to Lucerne buses for today, Sunday, May 24. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 4:00 PM Roma, Autostazione Tiburtina | 12h20 | 4:20 AM Luzern, Landenburgstrasse (Busparkplatz) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:55 PM Roma, Autostazione Tiburtina | 17h30 | 4:25 PM Luzern, Landenburgstrasse (Busparkplatz) | 2 transfers | |
| Monday, May 25 | |||||
FlixBus · FlixBus · FlixBus | 1:20 AM Roma, Autostazione Tiburtina | 15h05 | 4:25 PM Luzern, Landenburgstrasse (Busparkplatz) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:10 AM Roma, Autostazione (Metro Anagnina) | 15h00 | 2:10 AM Luzern, Landenburgstrasse (Busparkplatz) | 2 transfers | |
FlixBus · FlixBus | 12:10 PM Roma, Autostazione Tiburtina | 14h00 | 2:10 AM Luzern, Landenburgstrasse (Busparkplatz) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 12:55 PM Roma, Autostazione Tiburtina | 15h25 | 4:20 AM Luzern, Landenburgstrasse (Busparkplatz) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 15h15 | 4:20 AM Luzern, Landenburgstrasse (Busparkplatz) | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Lucerne by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 24
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Why should you book Rome to Lucerne buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Marino Autolinee to find the best option for your trip from Rome to Lucerne.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Rome to Lucerne.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Marino Autolinee to find the best option for your trip from Rome to Lucerne.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Rome to Lucerne.
Journey information
Overview: Bus from Rome to Lucerne
Buses from Rome to Lucerne run on average 7 times per day, taking around 12h 7m. Cheap bus tickets for this journey start at €38 if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 662 km distance in 13h 5m.
Distance 662 km |
Average bus duration 12h 7m |
Cheapest ticket price €38 |
Buses per day 7 |
Direct buses 1 |
Fastest bus 13h 5m |
First bus 12:10 AM |
Last bus 11:50 PM |
Cheapest Month Dec |
Cheapest Day Wed |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Sat |
Least Busy Day Sun |
Best time to book 5 days |
Bus providers: FlixBus, Marino Autolinee from Rome to LucerneYou can travel by bus between Rome to Lucerne with FlixBus, Marino Autolinee for as low as €38. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Marino Autolinee
FAQs: Bus from Rome to Lucerne
Find answers to the most common questions about traveling from Rome to Lucerne by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lucerne, this guide helps you travel smarter and with confidence.

- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Rome to Lucerne
Most popular bus connections from Rome
More options for your journey from Rome to Lucerne
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