Rome to Prague bus with FlixBus

Thu, Oct 08
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FlixBus
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National Express
2,000+ travel companies
FlixBus
Alsa
Avanza
BlaBlaCar Bus
National Express
2,000+ travel companies
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The cheapest and fastest buses from Rome to Prague

Showing times, prices and bookable tickets for Oct 08

Cheapest price on Oct 08

€106

Average ticket price on Oct 08

€132

Fastest journey on Oct 08

19 h 55 m

Average journey duration on Oct 08

20 h 15 m

Buses on Oct 08

43

Distance

923 km

Cheap tickets

The best way to find a cheap bus ticket from Rome to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Rome to Prague will cost around €132 if you buy it on the day, but the cheapest tickets can be found for only €106.

Fast buses

On Thu, Oct 08, we found 43 buses from Rome to Prague, including 2 direct services.

On Thu, Oct 08 the direct buses cover the 923 km distance in an average of 20 h 15 m but if you time it right, some buses will get you there in just 19 h 55 m .

On Thu, Oct 08 the slowest buses will take 20 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • FlixBusFlixBus · FlixBus
    7:30 AM22h15
    Roma, Autostazione Tiburtina
    5:45 AMPraha, ÚAN Florenc
    €1061One-way
    1 transfer
  • FlixBusFlixBus · FlixBus
    10:55 PM20h35
    Roma, Autostazione Tiburtina
    7:30 PMPraha, ÚAN Florenc
    €1181One-way
    1 transfer
  • FlixBusFlixBus · FlixBus
    10:55 PM20h25
    Roma, Autostazione Tiburtina
    7:20 PMPrague, Central Train Station
    €1181One-way
    1 transfer
  • FlixBusFlixBus · FlixBus · FlixBus
    10:55 PM24h00
    Roma, Autostazione Tiburtina
    10:55 PMPraha, Na Knížecí
    €1191One-way
    2 transfers
  • FlixBusFlixBus · FlixBus · FlixBus
    6:15 PM26h40
    Roma, Autostazione (Metro Anagnina)
    8:55 PMPraha, ÚAN Florenc
    €1251One-way
    2 transfers

Journey information

Overview: Bus from Rome to Prague

ItalyItaly
CzechiaCzechia
Icon of bus

Buses from Rome to Prague run on average 38 times per day, taking around 19h 49m. Cheap bus tickets for this journey start at €44 but you can travel from only €17 by flight.

There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 923 km distance in 16h 50m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from €17
Distance
923 km
Average bus duration
19h 49m
Cheapest ticket price
€44
Buses per day
38
Direct buses
2
Fastest bus
16h 50m
First bus
12:10 AM
Last bus
11:55 PM
Cheapest Month
Feb
Cheapest Day
Wed
High Season
Jul - Sep
Low Season
Apr - Jun
Busiest Day
Wed
Least Busy Day
Thu
Best time to book
91 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from €17

Live departures

Rome to Prague bus times

The table below shows live departures for Rome to Prague buses for tomorrow, Thursday, October 8. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBusFlixBus · FlixBus · FlixBus1:20 AM Roma, Autostazione Tiburtina
25h55
3:15 AM Prague, Central Train Station2 transfers
FlixBusFlixBus · FlixBus7:30 AM Roma, Autostazione Tiburtina
22h15
5:45 AM Praha, ÚAN Florenc1 transfer
FlixBusFlixBus · FlixBus · FlixBus9:30 AM Roma, Autostazione Tiburtina
23h25
8:55 AM Praha, Na Knížecí2 transfers
FlixBusFlixBus · FlixBus9:30 AM Roma, Autostazione Tiburtina
21h30
7:00 AM Prague, Central Train Station1 transfer
FlixBusFlixBus · FlixBus9:30 AM Roma, Autostazione Tiburtina
21h40
7:10 AM Praha, ÚAN Florenc1 transfer
FlixBusFlixBus · FlixBus · FlixBus9:30 AM Roma, Autostazione Tiburtina
22h00
7:30 AM Praha, M. Horákové (Hradčanská)2 transfers
FlixBusFlixBus · FlixBus · FlixBus10:40 AM Roma, Autostazione Tiburtina
24h50
11:30 AM Praha, Zličín2 transfers
FlixBusFlixBus · FlixBus10:40 AM Roma, Autostazione Tiburtina
23h55
10:35 AM Prague, Central Train Station1 transfer
FlixBusFlixBus · FlixBus · FlixBus12:00 PM Roma, Autostazione (Metro Anagnina)
24h45
12:45 PM Praha, Na Knížecí2 transfers
FlixBusFlixBus · FlixBus12:20 PM Roma, Autostazione Tiburtina
21h05
9:25 AM Praha, ÚAN Florenc1 transfer
FlixBusFlixBus · FlixBus · FlixBus12:20 PM Roma, Autostazione Tiburtina
24h25
12:45 PM Praha, Na Knížecí2 transfers
FlixBusFlixBus · FlixBus · FlixBus12:20 PM Roma, Autostazione Tiburtina
25h00
1:20 PM Prague, Central Train Station2 transfers
FlixBusFlixBus · FlixBus · FlixBus12:20 PM Roma, Autostazione Tiburtina
25h00
1:20 PM Praha, Roztyly2 transfers
FlixBusFlixBus · FlixBus · FlixBus12:20 PM Roma, Autostazione Tiburtina
25h25
1:45 PM Praha, Černý Most2 transfers
FlixBusFlixBus · FlixBus · FlixBus12:45 PM Roma, Autostazione (Metro Anagnina)
25h00
1:45 PM Praha, Černý Most2 transfers
FlixBusFlixBus · FlixBus · FlixBus12:45 PM Roma, Autostazione (Metro Anagnina)
24h35
1:20 PM Praha, Roztyly2 transfers
FlixBusFlixBus · FlixBus · FlixBus1:05 PM Roma, Autostazione (Metro Anagnina)
21h30
10:35 AM Prague, Central Train Station2 transfers
FlixBusFlixBus · FlixBus1:05 PM Roma, Autostazione (Metro Anagnina)
20h20
9:25 AM Praha, ÚAN Florenc1 transfer
FlixBusFlixBus · FlixBus · FlixBus1:05 PM Roma, Autostazione (Metro Anagnina)
24h25
1:30 PM Praha, Roztyly2 transfers
FlixBusFlixBus · FlixBus5:00 PM Roma, Autostazione Tiburtina
28h20
9:20 PM Prague, Central Train Station1 transfer
FlixBusFlixBus · FlixBus · FlixBus5:00 PM Roma, Autostazione Tiburtina
26h50
7:50 PM Praha, Zličín2 transfers
FlixBusFlixBus5:05 PM Roma, Autostazione Tiburtina
20h40
1:45 PM Prague, Central Train Station0 transfersDirect
FlixBusFlixBus5:05 PM Roma, Autostazione Tiburtina
20h50
1:55 PM Praha, ÚAN Florenc0 transfersDirect
FlixBusFlixBus · FlixBus · FlixBus5:05 PM Roma, Autostazione Tiburtina
26h55
8:00 PM Praha, Roztyly2 transfers
FlixBusFlixBus · FlixBus · FlixBus5:05 PM Roma, Autostazione Tiburtina
23h05
4:10 PM Praha, Černý Most2 transfers
FlixBusFlixBus · FlixBus · FlixBus5:05 PM Roma, Autostazione Tiburtina
26h55
8:00 PM Praha, M. Horákové (Hradčanská)2 transfers
FlixBusFlixBus · FlixBus · FlixBus5:25 PM Roma, Autostazione (Metro Anagnina)
25h45
7:10 PM Praha, Na Knížecí2 transfers
FlixBusFlixBus · FlixBus · FlixBus5:25 PM Roma, Autostazione (Metro Anagnina)
20h05
1:30 PM Praha, ÚAN Florenc2 transfers
FlixBusFlixBus · FlixBus · FlixBus5:25 PM Roma, Autostazione (Metro Anagnina)
22h45
4:10 PM Praha, Černý Most2 transfers
FlixBusFlixBus · FlixBus · FlixBus5:25 PM Roma, Autostazione (Metro Anagnina)
19h55
1:20 PM Prague, Central Train Station2 transfers
FlixBusFlixBus · FlixBus · FlixBus5:25 PM Roma, Autostazione (Metro Anagnina)
26h35
8:00 PM Praha, M. Horákové (Hradčanská)2 transfers
FlixBusFlixBus · FlixBus · FlixBus6:15 PM Roma, Autostazione (Metro Anagnina)
26h40
8:55 PM Praha, ÚAN Florenc2 transfers
FlixBusFlixBus · FlixBus · FlixBus6:15 PM Roma, Autostazione (Metro Anagnina)
27h15
9:30 PM Praha, Černý Most2 transfers
FlixBusFlixBus · FlixBus · FlixBus9:00 PM Roma, Autostazione Tiburtina
22h10
7:10 PM Praha, Na Knížecí2 transfers
FlixBusFlixBus · FlixBus · FlixBus9:00 PM Roma, Autostazione Tiburtina
26h55
11:55 PM Prague, Central Train Station2 transfers
FlixBusFlixBus · FlixBus9:00 PM Roma, Autostazione Tiburtina
20h30
5:30 PM Prague, Central Train Station1 transfer
FlixBusFlixBus · FlixBus9:00 PM Roma, Autostazione Tiburtina
20h45
5:45 PM Praha, ÚAN Florenc1 transfer
FlixBusFlixBus · FlixBus · FlixBus10:45 PM Roma, Autostazione Tiburtina
22h45
9:30 PM Praha, Černý Most2 transfers
FlixBusFlixBus · FlixBus10:55 PM Roma, Autostazione Tiburtina
20h35
7:30 PM Praha, ÚAN Florenc1 transfer
FlixBusFlixBus · FlixBus · FlixBus10:55 PM Roma, Autostazione Tiburtina
24h00
10:55 PM Praha, Na Knížecí2 transfers
FlixBusFlixBus · FlixBus · FlixBus10:55 PM Roma, Autostazione Tiburtina
27h55
2:50 AM Prague, Central Train Station2 transfers
FlixBusFlixBus · FlixBus10:55 PM Roma, Autostazione Tiburtina
20h25
7:20 PM Prague, Central Train Station1 transfer
FlixBusFlixBus · FlixBus · FlixBus11:35 PM Roma, Autostazione (Metro Anagnina)
27h40
3:15 AM Prague, Central Train Station2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Why should you book Rome to Prague buses with Omio?

FlixBus operates all buses services from Rome to Prague.
Omio is an official ticket reseller for all your travel options from Rome to Prague.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome to Prague.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome to Prague.

Bus providers: FlixBus from Rome to PragueYou can travel by bus between Rome to Prague with FlixBus for as low as €17. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
16h 50m
Cheapest FlixBus Price
€44
FlixBus frequency
41 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

FAQs: Bus from Rome to Prague

Find answers to the most common questions about traveling from Rome to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

FAQs
Cheap coach tickets from Rome to Prague can start from as little as €44 when you book in advance. The average coach ticket price for Rome to Prague is €93; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by coach from Rome to Prague is 16h 50m to travel the 923 km long trip. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest coach from Rome to Prague leaves at 12:10 AM. Plan your trip with the Journey Planner from Omio.
The latest coach from Rome to Prague leaves at 11:55 PM.
Yes, there are 2 direct coaches a day from Rome to Prague with FlixBus. Schedules can vary on holidays or weekends with fewer direct coaches.
When taking a coach from Rome to Prague, you can count on FlixBus for the best way to get you to Prague. You can also check all possible coach companies who offer a service between Rome and Prague and compare the amenities they offer before buying a coach ticket.
When departing from Rome , you have various coach station options to start your trip from including Roma, Autostazione Tiburtina, Roma, Autostazione (Metro Anagnina), Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine" . When arriving in Prague , you can end your trip in coach stations like Prague, Central Train Station, Praha, ÚAN Florenc, Praha, Na Knížecí, Praha, Roztyly, Praha, Černý Most, Praha, M. Horákové (Hradčanská), Praha, Zličín, Praha, Letiště Václava Havla .Passengers board the coach most frequently from Roma, Autostazione Tiburtina, which is located around 4 km away from the city centre, and they get off the coach at Prague, Central Train Station, located 1 away from the city centre.
It's helpful to compare your options as there are 3 ways to travel between Rome and Prague including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the coach from Rome to Prague:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the coach from Rome to Prague for coach company FlixBus.
Whether you can cancel your coach ticket from Rome to Prague depends on the coach companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the coach with coach company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the coach from Rome to Prague.
Yes, the following luggage options are included when booking a coach ticket from Rome to Prague:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a coach ticket from Rome to Prague:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the coach from Rome to Prague. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the coach from Rome to Prague with the following coach company: FlixBus
Yes, there are USB plugs on board the coach from Rome to Prague with the following coach company: FlixBus.
Yes, there is Wifi on board the coach from Rome to Prague with the following coach company: FlixBus.

popular bus stations

Popular bus stations from Rome to Prague

Most Rome to Prague buses use the Roma, Autostazione Tiburtina to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Rome and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Rome
Arrival bus stations in Prague

Which Rome station do buses to Prague leave from?

Buses from Rome to Prague leave from Roma, Autostazione Tiburtina. The station is 4 km from Rome city centre at Largo Guido Mazzoni, snc, 00162 Roma RM, Italy.
Roma, Autostazione TiburtinaLargo Guido Mazzoni, snc, 00162 Roma RM, ItalyWifiParkingDiningATMTaxisAccessibilityWCShowerTicket Office
City-centre transport

Getting to Roma, Autostazione Tiburtina from Rome city centre

Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:

Bus490, 495 · 16m · €2 · every ~22 min
SubwayMeb · 7m · €2 · every ~15 min

Roma, Autostazione Tiburtina bus station facilities and services

Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.

Food and drink

Food options include: Cafes and vending machines available.

Wi-Fi and ATMs

Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.

Tickets and information

Ticket office support is available at Roma, Autostazione Tiburtina.

Parking, taxis and toilets

Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.

Accessibility

Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.

Roma, Autostazione (Metro Anagnina)Rome Anagnina, Via Tuscolana, 173
City-centre transport

Getting to Roma, Autostazione (Metro Anagnina) from Rome city centre

BusRome Fiumicino, Scario · 31m · €1
nMA · 38m · €2 · every ~4 min
SubwayMea · 24m · €2 · every ~29 min
Shuttle31m · €10
Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine"
City-centre transport

Getting to Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine" from Rome city centre

TrainRe, 12629 · 15m · €2 · every ~8 min
BusN574, 522, 554, 546, N522 · 25m · €1
30m · €2
40m · €7 · every ~3 min
SIT Bus Shuttle · 45m · €4

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