Rome to Prague bus with FlixBus

Thu, Apr 09
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RegioJet a.s.
National Express
Itabus
2,000+ travel companies
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The cheapest and fastest buses from Rome to Prague

Showing times and prices for Apr 11

Cheapest price

€121

Average price

€169

Fastest journey

19 h 55 m

Average duration

20 h 15 m

Buses per day

45

Distance

923 km

Cheap tickets

The best way to find a cheap bus ticket from Rome to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Rome to Prague will cost around €169 if you buy it on the day, but the cheapest tickets can be found for only €121.

Fast buses

Of the 45 buses that leave Rome for Prague on Sat, Apr 11, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.

On Sat, Apr 11 the direct buses cover the 923 km distance in an average of 20 h 15 m but if you time it right, some buses will get you there in just 19 h 55 m .

On Sat, Apr 11 the slowest buses will take 20 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • FlixBusFlixBus · FlixBus · FlixBus
    1:05 PM24h25
    Roma, Autostazione (Metro Anagnina)
    1:30 PMPraha, Roztyly
    1211One-way
    2 transfers
  • FlixBusFlixBus · FlixBus · FlixBus
    6:15 PM27h15
    Roma, Autostazione (Metro Anagnina)
    9:30 PMPraha, Černý Most
    1231One-way
    2 transfers
  • FlixBusFlixBus · FlixBus · FlixBus
    6:15 PM26h40
    Roma, Autostazione (Metro Anagnina)
    8:55 PMPraha, ÚAN Florenc
    1231One-way
    2 transfers
  • FlixBusFlixBus · FlixBus
    7:30 AM22h15
    Roma, Autostazione Tiburtina
    5:45 AMPraha, ÚAN Florenc
    1271One-way
    1 transfer
  • FlixBusFlixBus · FlixBus · FlixBus
    1:05 PM21h30
    Roma, Autostazione (Metro Anagnina)
    10:35 AMPrague, Central Train Station
    1281One-way
    2 transfers

Travel Information

Compare train, bus, and flight for Rome to Prague

Omio recommends booking the flight as it is the most popular option from Rome to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €55. For those with little time consider booking a flight which can get you there in 2h 49m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a bus costs an average of €55, and a train costs an average of €188.

Distance: 923 km

Compare bus with

Bus
Most popular
Flight
Train

€94

Average price

Cheapest

€114

Average price

€211

Average price

20h 15m

Average total duration

19h 45m

Onboard

+

30m

Additional time*

5h 49m

Average total duration

Fastest

2h 49m

Onboard

+

3h 0m

Additional time*

18h 2m

Average total duration

17h 32m

Onboard

+

30m

Additional time*

0.9 - 2.3kg

CO2 emissions

Lowest

2.8 - 5.5kg

CO2 emissions

-

CO2 emissions

FlixBus

Most popular bus company

Malta Air

Most popular airline

ÖBB | Nightjet

Most popular train company

Direct Options

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Live departures

Rome to Prague bus times

The table below shows live departures for Rome to Prague buses for today, Friday, April 10. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
meinfernbus_flixbusFlixBus · FlixBus8:40 AM Roma, Autostazione Tiburtina
23h55
8:35 AM Prague, Central Train Station1 transfer
meinfernbus_flixbusFlixBus · FlixBus · FlixBus8:40 AM Roma, Autostazione Tiburtina
24h50
9:30 AM Praha, Zličín2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus9:50 AM Roma, Autostazione (Metro Anagnina)
23h55
9:45 AM Praha, Na Knížecí2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus10:10 AM Roma, Autostazione Tiburtina
24h00
10:10 AM Prague, Central Train Station2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus10:20 AM Roma, Autostazione Tiburtina
25h25
11:45 AM Praha, Černý Most2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus10:20 AM Roma, Autostazione Tiburtina
23h25
9:45 AM Praha, Na Knížecí2 transfers
meinfernbus_flixbusFlixBus · FlixBus10:20 AM Roma, Autostazione Tiburtina
21h05
7:25 AM Praha, ÚAN Florenc1 transfer
meinfernbus_flixbusFlixBus · FlixBus · FlixBus10:20 AM Roma, Autostazione Tiburtina
25h00
11:20 AM Praha, Roztyly2 transfers
meinfernbus_flixbusFlixBus · FlixBus11:05 AM Roma, Autostazione (Metro Anagnina)
20h20
7:25 AM Praha, ÚAN Florenc1 transfer
meinfernbus_flixbusFlixBus · FlixBus · FlixBus11:05 AM Roma, Autostazione (Metro Anagnina)
27h05
2:10 PM Praha, Černý Most2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus11:05 AM Roma, Autostazione (Metro Anagnina)
24h25
11:30 AM Praha, Roztyly2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus11:05 AM Roma, Autostazione (Metro Anagnina)
28h30
3:35 PM Praha, M. Horákové (Hradčanská)2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus11:05 AM Roma, Autostazione (Metro Anagnina)
21h30
8:35 AM Prague, Central Train Station2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus3:05 PM Roma, Autostazione Tiburtina
25h25
4:30 PM Praha, Zličín2 transfers
meinfernbus_flixbusFlixBus3:05 PM Roma, Autostazione Tiburtina
20h50
11:55 AM Praha, ÚAN Florenc0 transfersDirect
meinfernbus_flixbusFlixBus3:05 PM Roma, Autostazione Tiburtina
20h40
11:45 AM Prague, Central Train Station0 transfersDirect
meinfernbus_flixbusFlixBus · FlixBus · FlixBus3:05 PM Roma, Autostazione Tiburtina
26h05
5:10 PM Praha, Na Knížecí2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus3:05 PM Roma, Autostazione Tiburtina
23h05
2:10 PM Praha, Černý Most2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus3:05 PM Roma, Autostazione Tiburtina
23h25
2:30 PM Praha, Roztyly2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus3:05 PM Roma, Autostazione Tiburtina
24h30
3:35 PM Praha, M. Horákové (Hradčanská)2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus3:25 PM Roma, Autostazione (Metro Anagnina)
24h05
3:30 PM Prague, Central Train Station2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus3:25 PM Roma, Autostazione (Metro Anagnina)
28h05
7:30 PM Praha, Černý Most2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus3:25 PM Roma, Autostazione (Metro Anagnina)
26h55
6:20 PM Praha, Na Knížecí2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus3:25 PM Roma, Autostazione (Metro Anagnina)
24h20
3:45 PM Praha, ÚAN Florenc2 transfers
meinfernbus_flixbusFlixBus · FlixBus7:00 PM Roma, Autostazione Tiburtina
20h30
3:30 PM Prague, Central Train Station1 transfer
meinfernbus_flixbusFlixBus · FlixBus · FlixBus7:00 PM Roma, Autostazione Tiburtina
23h20
6:20 PM Praha, Na Knížecí2 transfers
meinfernbus_flixbusFlixBus · FlixBus7:00 PM Roma, Autostazione Tiburtina
20h45
3:45 PM Praha, ÚAN Florenc1 transfer
meinfernbus_flixbusFlixBus · FlixBus · FlixBus7:00 PM Roma, Autostazione Tiburtina
26h55
9:55 PM Prague, Central Train Station2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus8:45 PM Roma, Autostazione Tiburtina
22h45
7:30 PM Praha, Černý Most2 transfers
meinfernbus_flixbusFlixBus · FlixBus8:55 PM Roma, Autostazione Tiburtina
20h35
5:30 PM Praha, ÚAN Florenc1 transfer
meinfernbus_flixbusFlixBus · FlixBus8:55 PM Roma, Autostazione Tiburtina
20h25
5:20 PM Prague, Central Train Station1 transfer
meinfernbus_flixbusFlixBus · FlixBus · FlixBus8:55 PM Roma, Autostazione Tiburtina
27h55
12:50 AM Prague, Central Train Station2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus8:55 PM Roma, Autostazione Tiburtina
24h00
8:55 PM Praha, Na Knížecí2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus11:40 PM Roma, Autostazione Tiburtina
25h35
1:15 AM Prague, Central Train Station2 transfers
Saturday, April 11
meinfernbus_flixbusFlixBus · FlixBus5:30 AM Roma, Autostazione Tiburtina
22h15
3:45 AM Praha, ÚAN Florenc1 transfer
meinfernbus_flixbusFlixBus · FlixBus7:30 AM Roma, Autostazione Tiburtina
21h30
5:00 AM Prague, Central Train Station1 transfer
meinfernbus_flixbusFlixBus · FlixBus · FlixBus7:30 AM Roma, Autostazione Tiburtina
23h25
6:55 AM Praha, Na Knížecí2 transfers
meinfernbus_flixbusFlixBus · FlixBus · FlixBus7:30 AM Roma, Autostazione Tiburtina
22h00
5:30 AM Praha, M. Horákové (Hradčanská)2 transfers
meinfernbus_flixbusFlixBus · FlixBus7:30 AM Roma, Autostazione Tiburtina
21h40
5:10 AM Praha, ÚAN Florenc1 transfer
meinfernbus_flixbusFlixBus · FlixBus · FlixBus7:30 AM Roma, Autostazione Tiburtina
26h00
9:30 AM Prague, Central Train Station2 transfers

Find all the dates and times for this journey

Compare prices and tickets Rome to Prague by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Rome to Prague buses with Omio?

FlixBus operates all buses services from Rome to Prague.
Omio is an official ticket reseller for all your travel options from Rome to Prague.

Why book with Omio vs FlixBus?

  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome to Prague.

Why book with Omio over Wanderu or Trainline?

  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome to Prague.

Journey information

Overview: Bus from Rome to Prague

ItalyItaly
CzechiaCzechia
Icon of bus

Buses from Rome to Prague run on average 37 times per day, taking around 19h 45m. Cheap bus tickets for this journey start at €55 but you can travel from only €20 by flight.

There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 923 km distance in 20h 10m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from €20
Distance
923 km
Average bus duration
19h 45m
Cheapest ticket price
€55
Buses per day
37
Direct buses
2
Fastest bus
20h 10m
First bus
12:10 AM
Last bus
11:55 PM
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Flight from €20

Bus providers: FlixBus from Rome to PragueYou can travel by bus between Rome to Prague with FlixBus for as low as €20. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
20h 20m
Cheapest Price
€55
FlixBus frequency
1 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

FAQs: Bus from Rome to Prague

Find answers to the most common questions about traveling from Rome to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

FAQs
Cheap coach tickets from Rome to Prague can start from as little as €55 when you book in advance. The average coach ticket price for Rome to Prague is €94; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by coach from Rome to Prague is 20h 10m to travel the 923 km long trip. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest coach from Rome to Prague leaves at 12:10 AM. Plan your trip with the Journey Planner from Omio.
The latest coach from Rome to Prague leaves at 11:55 PM.
Yes, there are 2 direct coaches a day from Rome to Prague with FlixBus. Schedules can vary on holidays or weekends with fewer direct coaches.
When taking a coach from Rome to Prague, you can count on FlixBus for the best way to get you to Prague. You can also check all possible coach companies who offer a service between Rome and Prague and compare the amenities they offer before buying a coach ticket.
A trip to Prague from Rome is worth doing but not as a day trip with a journey time of 20h 10m each way. Check with Omio app the best way to travel.
The cheapest month for a coach from Rome to Prague is May.
It's helpful to compare your options as there are 3 ways to travel between Rome and Prague including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the coach from Rome to Prague:
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the coach from Rome to Prague for coach company FlixBus.
Whether you can cancel your coach ticket from Rome to Prague depends on the coach companies:
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the coach with coach company FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the coach from Rome to Prague.
Yes, the following luggage options are included when booking a coach ticket from Rome to Prague:
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a coach ticket from Rome to Prague:
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the coach from Rome to Prague. The following conditions apply:
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the coach from Rome to Prague with the following coach company: FlixBus
Yes, there are USB plugs on board the coach from Rome to Prague with the following coach company: FlixBus.
Yes, there is Wifi on board the coach from Rome to Prague with the following coach company: FlixBus.

popular bus stations

Popular bus stations from Rome to Prague

Rome
Prague
The major bus station for departures in Rome is Roma, Autostazione Tiburtina. Find all the information you need to know about services, amenities and connections at Roma, Autostazione Tiburtina for your trip from Rome to Prague.
Roma, Autostazione Tiburtina
information
Roma, Autostazione (Metro Anagnina)
Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine"
information

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