The cheapest and fastest buses from Rome to Prague
Cheapest price
€109
Average price
€120
Fastest journey
20 h 30 m
Average duration
20 h 57 m
Buses per day
32
Distance
923 km
The best way to find a cheap bus ticket from Rome to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Prague will cost around €120 if you buy it on the day, but the cheapest tickets can be found for only €109.
Of the 32 buses that leave Rome for Prague on Tue, May 26, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Tue, May 26 the direct buses cover the 923 km distance in an average of 20 h 57 m but if you time it right, some buses will get you there in just 20 h 30 m .
On Tue, May 26 the slowest buses will take 22 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus5:05 PM20h50Roma, Autostazione Tiburtina1:55 PMPraha, ÚAN Florenc€1091One-way0 transfers
FlixBus5:05 PM20h40Roma, Autostazione Tiburtina1:45 PMPrague, Central Train Station€1091One-way0 transfers
FlixBus · FlixBus · FlixBus1:05 PM28h30Roma, Autostazione (Metro Anagnina)5:35 PMPraha, M. Horákové (Hradčanská)€1121One-way2 transfers
FlixBus · FlixBus5:00 PM27h00Roma, Autostazione Tiburtina8:00 PMPrague, Central Train Station€1121One-way1 transfer
FlixBus · FlixBus · FlixBus9:30 AM23h25Roma, Autostazione Tiburtina8:55 AMPraha, Na Knížecí€1121One-way2 transfers
FlixBus · FlixBus9:00 PM20h30Roma, Autostazione Tiburtina5:30 PMPrague, Central Train Station€1121One-way1 transfer
FlixBus5:05 PM20h40Roma, Autostazione Tiburtina1:45 PMPrague, Central Train Station€1091One-way0 transfers
FlixBus · FlixBus9:00 PM20h45Roma, Autostazione Tiburtina5:45 PMPraha, ÚAN Florenc€1121One-way1 transfer
FlixBus5:05 PM20h50Roma, Autostazione Tiburtina1:55 PMPraha, ÚAN Florenc€1091One-way0 transfers
FlixBus · FlixBus · FlixBus9:30 AM22h00Roma, Autostazione Tiburtina7:30 AMPraha, M. Horákové (Hradčanská)€1181One-way2 transfers
Travel Information
Compare train, bus, and flight for Rome to Prague
Omio recommends booking the flight as it is the most popular option from Rome to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €56. For those with little time consider booking a flight which can get you there in 2h 50m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a bus costs an average of €56, and a train costs an average of €236.
Distance: 923 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€91 Average price Cheapest | €122 Average price | €239 Average price |
20h 23m Average total duration 19h 53m Onboard + 30m Additional time* | 5h 50m Average total duration Fastest 2h 50m Onboard + 3h 0m Additional time* | 18h 2m Average total duration 17h 32m Onboard + 30m Additional time* |
0.9 - 2.3kg CO2 emissions Lowest | 2.8 - 5.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Rome to Prague bus times
The table below shows live departures for Rome to Prague buses for today, Monday, May 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 24h25 | 1:30 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 27h05 | 4:10 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 28h30 | 5:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 21h30 | 10:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 20h20 | 9:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 5:00 PM Roma, Autostazione Tiburtina | 27h00 | 8:00 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 5:00 PM Roma, Autostazione Tiburtina | 24h35 | 5:35 PM Praha, M. Horákové (Hradčanská) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 23h25 | 4:30 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 23h05 | 4:10 PM Praha, Černý Most | 2 transfers | |
FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 20h40 | 1:45 PM Prague, Central Train Station | 0 transfersDirect | |
FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 20h50 | 1:55 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 22h10 | 7:10 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 26h55 | 11:55 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 20h45 | 5:45 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 9:00 PM Roma, Autostazione Tiburtina | 20h30 | 5:30 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 9:20 PM Roma, Autostazione Tiburtina | 24h30 | 9:50 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:45 PM Roma, Autostazione Tiburtina | 23h30 | 10:15 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:45 PM Roma, Autostazione Tiburtina | 22h45 | 9:30 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:35 PM Roma, Autostazione (Metro Anagnina) | 27h40 | 3:15 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:50 PM Roma, Autostazione Tiburtina | 27h25 | 3:15 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 23h25 | 8:55 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 22h00 | 7:30 AM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:30 AM Roma, Autostazione Tiburtina | 28h30 | 2:00 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 10:40 AM Roma, Autostazione Tiburtina | 23h55 | 10:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:40 AM Roma, Autostazione Tiburtina | 24h50 | 11:30 AM Praha, Zličín | 2 transfers | |
FlixBus · FlixBus | 10:40 AM Roma, Autostazione Tiburtina | 24h05 | 10:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:10 AM Roma, Autostazione (Metro Anagnina) | 25h15 | 12:25 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:50 AM Roma, Autostazione (Metro Anagnina) | 24h20 | 12:10 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:50 AM Roma, Autostazione (Metro Anagnina) | 24h55 | 12:45 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:10 PM Roma, Autostazione Tiburtina | 24h00 | 12:10 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 24h25 | 12:45 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 25h25 | 1:45 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 25h00 | 1:20 PM Praha, Roztyly | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 25
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Why should you book Rome to Prague buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome to Prague.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome to Prague.
Journey information
Overview: Bus from Rome to Prague
Buses from Rome to Prague run on average 38 times per day, taking around 19h 53m. Cheap bus tickets for this journey start at €56 but you can travel from only €15 by flight.
There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 923 km distance in 20h 10m.
Distance 923 km |
Average bus duration 19h 53m |
Cheapest ticket price €56 |
Buses per day 38 |
Direct buses 2 |
Fastest bus 20h 10m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month May |
Cheapest Day Wed |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 28 days |
Bus providers: FlixBus from Rome to PragueYou can travel by bus between Rome to Prague with FlixBus for as low as €15. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Rome to Prague
Find answers to the most common questions about traveling from Rome to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Rome to Prague
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
Most popular bus connections from Rome
More options for your journey from Rome to Prague
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