The cheapest and fastest buses from Rome to Prague
Cheapest price
€114
Average price
€136
Fastest journey
20 h 20 m
Average duration
20 h 32 m
Buses per day
28
Distance
923 km
The best way to find a cheap bus ticket from Rome to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Prague will cost around €136 if you buy it on the day, but the cheapest tickets can be found for only €114.
Of the 28 buses that leave Rome for Prague on Mon, Nov 24, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Nov 24 the direct buses cover the 923 km distance in an average of 20 h 32 m but if you time it right, some buses will get you there in just 20 h 20 m .
On Mon, Nov 24 the slowest buses will take 20 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
FlixBus · FlixBusTravel Information
Compare train, bus, and flight for Rome to Prague
Omio recommends booking the flight as it is the most popular option from Rome to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €64. For those with little time consider booking a flight which can get you there in 2h 48m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a bus costs an average of €64, and a train costs an average of €131.
Distance: 923 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€114 Average price Cheapest | €138 Average price | €174 Average price |
20h 8m Average total duration 19h 38m Onboard + 30m Additional time* | 5h 48m Average total duration Fastest 2h 48m Onboard + 3h 0m Additional time* | 18h 2m Average total duration 17h 32m Onboard + 30m Additional time* |
0.9 - 2.3kg CO2 emissions Lowest | 2.8 - 5.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Rome to Prague bus times
The table below shows live departures for Rome to Prague buses for tomorrow, Monday, November 24. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 12:40 AM Roma, Autostazione Tiburtina | 28h05 | 4:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 8:30 AM Roma, Autostazione Tiburtina | 20h30 | 5:00 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 8:30 AM Roma, Autostazione Tiburtina | 20h45 | 5:15 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:40 AM Roma, Autostazione Tiburtina | 24h50 | 10:30 AM Praha, Zličín | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:50 AM Roma, Autostazione (Metro Anagnina) | 22h45 | 9:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:50 AM Roma, Autostazione (Metro Anagnina) | 24h35 | 11:25 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:50 AM Roma, Autostazione Tiburtina | 22h45 | 9:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 11:20 AM Roma, Autostazione Tiburtina | 21h05 | 8:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:20 AM Roma, Autostazione Tiburtina | 24h05 | 11:25 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:45 AM Roma, Autostazione (Metro Anagnina) | 27h45 | 3:30 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:05 PM Roma, Autostazione (Metro Anagnina) | 27h05 | 3:10 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus | 12:05 PM Roma, Autostazione (Metro Anagnina) | 24h35 | 12:40 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 12:05 PM Roma, Autostazione (Metro Anagnina) | 28h30 | 4:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus | 12:05 PM Roma, Autostazione (Metro Anagnina) | 20h20 | 8:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 4:00 PM Roma, Autostazione Tiburtina | 27h00 | 7:00 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 4:00 PM Roma, Autostazione Tiburtina | 24h35 | 4:35 PM Praha, M. Horákové (Hradčanská) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:05 PM Roma, Autostazione Tiburtina | 26h05 | 6:10 PM Praha, Na Knížecí | 2 transfers | |
FlixBus | 4:05 PM Roma, Autostazione Tiburtina | 20h45 | 12:50 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 4:05 PM Roma, Autostazione Tiburtina | 23h05 | 3:10 PM Praha, Černý Most | 2 transfers | |
FlixBus | 4:05 PM Roma, Autostazione Tiburtina | 20h35 | 12:40 PM Prague, Central Train Station | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 4:05 PM Roma, Autostazione Tiburtina | 23h25 | 3:30 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus | 8:00 PM Roma, Autostazione Tiburtina | 20h30 | 4:30 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 8:00 PM Roma, Autostazione Tiburtina | 20h45 | 4:45 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 8:20 PM Roma, Autostazione Tiburtina | 24h30 | 8:50 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 9:45 PM Roma, Autostazione Tiburtina | 23h30 | 9:15 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus | 10:05 PM Roma, Autostazione Tiburtina | 22h50 | 8:55 PM Praha, Černý Most | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:05 PM Roma, Autostazione Tiburtina | 23h30 | 9:35 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus | 10:05 PM Roma, Autostazione Tiburtina | 22h15 | 8:20 PM Praha, ÚAN Florenc | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 24
Nov 25
Nov 26
Nov 27
Nov 28
Nov 29
Nov 30
Dec 01
Dec 02
Dec 03
Dec 04
Dec 05
Dec 06
Dec 07
Dec 08
Dec 09
Dec 10
Dec 11
Dec 12
Dec 13
Dec 14
Journey information
Overview: Bus from Rome to Prague
Buses from Rome to Prague run on average 37 times per day, taking around 19h 38m. Cheap bus tickets for this journey start at €64 but you can travel from only €31 by flight.
There are 1 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 923 km distance in 20h 10m.
Distance 923 km |
Average bus duration 19h 38m |
Cheapest ticket price €64 |
Buses per day 37 |
Direct buses 1 |
Fastest bus 20h 10m |
First bus 00:10 |
Last bus 23:55 |
Bus providers: FlixBus from Rome to PragueYou can travel by bus between Rome to Prague with FlixBus for as low as €31. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Rome to Prague
Find answers to the most common questions about traveling from Rome to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

When departing from Rome, you have various coach station options to start your route from including Rome, Termini (G), Rome, Roma Ostiense and Rome, Termini. When arriving in Prague, you can end your route in coach stations like Prague Tupolevova, Prague, Central Train Station and Prague.
Passengers board the coach most frequently from Rome, Termini (G), which is located around 1.4 miles (2.2 km) away from the city centre, and they get off the coach at Prague Tupolevova, located 5.8 miles (9.3 km) away from the city centre.
popular bus stations
Popular bus stations from Rome to Prague
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- 00:00-23:59
- Free Wi-Fi
- Cafeteria Černý Most (in the station)
- Czech Bistro (in the station)
- Fast Food Express (in the station).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 177, 195, 201 Metro: B
- Bus: 131, 174, 180 Metro: A Train: S4, S5
Most popular bus connections from Rome
More options for your journey from Rome to Prague
Here are some other resources that might have the information you need


