The cheapest and fastest buses from Rome to Prague
Cheapest price
€121
Average price
€169
Fastest journey
19 h 55 m
Average duration
20 h 15 m
Buses per day
45
Distance
923 km
The best way to find a cheap bus ticket from Rome to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Prague will cost around €169 if you buy it on the day, but the cheapest tickets can be found for only €121.
Of the 45 buses that leave Rome for Prague on Sat, Apr 11, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Apr 11 the direct buses cover the 923 km distance in an average of 20 h 15 m but if you time it right, some buses will get you there in just 19 h 55 m .
On Sat, Apr 11 the slowest buses will take 20 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus · FlixBus · FlixBus1:05 PM24h25Roma, Autostazione (Metro Anagnina)1:30 PMPraha, Roztyly€1211One-way2 transfers
FlixBus · FlixBus · FlixBus6:15 PM27h15Roma, Autostazione (Metro Anagnina)9:30 PMPraha, Černý Most€1231One-way2 transfers
FlixBus · FlixBus · FlixBus6:15 PM26h40Roma, Autostazione (Metro Anagnina)8:55 PMPraha, ÚAN Florenc€1231One-way2 transfers
FlixBus · FlixBus7:30 AM22h15Roma, Autostazione Tiburtina5:45 AMPraha, ÚAN Florenc€1271One-way1 transfer
FlixBus · FlixBus · FlixBus1:05 PM21h30Roma, Autostazione (Metro Anagnina)10:35 AMPrague, Central Train Station€1281One-way2 transfers
FlixBus · FlixBus · FlixBus5:25 PM19h55Roma, Autostazione (Metro Anagnina)1:20 PMPrague, Central Train Station€1771One-way2 transfers
FlixBus · FlixBus · FlixBus5:25 PM20h05Roma, Autostazione (Metro Anagnina)1:30 PMPraha, ÚAN Florenc€1771One-way2 transfers
FlixBus · FlixBus1:05 PM20h20Roma, Autostazione (Metro Anagnina)9:25 AMPraha, ÚAN Florenc€1281One-way1 transfer
FlixBus · FlixBus10:55 PM20h25Roma, Autostazione Tiburtina7:20 PMPrague, Central Train Station€2051One-way1 transfer
FlixBus · FlixBus9:00 PM20h30Roma, Autostazione Tiburtina5:30 PMPrague, Central Train Station€1581One-way1 transfer
Travel Information
Compare train, bus, and flight for Rome to Prague
Omio recommends booking the flight as it is the most popular option from Rome to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €55. For those with little time consider booking a flight which can get you there in 2h 49m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a bus costs an average of €55, and a train costs an average of €188.
Distance: 923 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€94 Average price Cheapest | €114 Average price | €211 Average price |
20h 15m Average total duration 19h 45m Onboard + 30m Additional time* | 5h 49m Average total duration Fastest 2h 49m Onboard + 3h 0m Additional time* | 18h 2m Average total duration 17h 32m Onboard + 30m Additional time* |
0.9 - 2.3kg CO2 emissions Lowest | 2.8 - 5.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Rome to Prague bus times
The table below shows live departures for Rome to Prague buses for today, Friday, April 10. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 8:40 AM Roma, Autostazione Tiburtina | 23h55 | 8:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 8:40 AM Roma, Autostazione Tiburtina | 24h50 | 9:30 AM Praha, Zličín | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:50 AM Roma, Autostazione (Metro Anagnina) | 23h55 | 9:45 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:10 AM Roma, Autostazione Tiburtina | 24h00 | 10:10 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:20 AM Roma, Autostazione Tiburtina | 25h25 | 11:45 AM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:20 AM Roma, Autostazione Tiburtina | 23h25 | 9:45 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 10:20 AM Roma, Autostazione Tiburtina | 21h05 | 7:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:20 AM Roma, Autostazione Tiburtina | 25h00 | 11:20 AM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus | 11:05 AM Roma, Autostazione (Metro Anagnina) | 20h20 | 7:25 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:05 AM Roma, Autostazione (Metro Anagnina) | 27h05 | 2:10 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:05 AM Roma, Autostazione (Metro Anagnina) | 24h25 | 11:30 AM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:05 AM Roma, Autostazione (Metro Anagnina) | 28h30 | 3:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:05 AM Roma, Autostazione (Metro Anagnina) | 21h30 | 8:35 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:05 PM Roma, Autostazione Tiburtina | 25h25 | 4:30 PM Praha, Zličín | 2 transfers | |
FlixBus | 3:05 PM Roma, Autostazione Tiburtina | 20h50 | 11:55 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 3:05 PM Roma, Autostazione Tiburtina | 20h40 | 11:45 AM Prague, Central Train Station | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 3:05 PM Roma, Autostazione Tiburtina | 26h05 | 5:10 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:05 PM Roma, Autostazione Tiburtina | 23h05 | 2:10 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:05 PM Roma, Autostazione Tiburtina | 23h25 | 2:30 PM Praha, Roztyly | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:05 PM Roma, Autostazione Tiburtina | 24h30 | 3:35 PM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:25 PM Roma, Autostazione (Metro Anagnina) | 24h05 | 3:30 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:25 PM Roma, Autostazione (Metro Anagnina) | 28h05 | 7:30 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:25 PM Roma, Autostazione (Metro Anagnina) | 26h55 | 6:20 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:25 PM Roma, Autostazione (Metro Anagnina) | 24h20 | 3:45 PM Praha, ÚAN Florenc | 2 transfers | |
FlixBus · FlixBus | 7:00 PM Roma, Autostazione Tiburtina | 20h30 | 3:30 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 7:00 PM Roma, Autostazione Tiburtina | 23h20 | 6:20 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus | 7:00 PM Roma, Autostazione Tiburtina | 20h45 | 3:45 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 7:00 PM Roma, Autostazione Tiburtina | 26h55 | 9:55 PM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:45 PM Roma, Autostazione Tiburtina | 22h45 | 7:30 PM Praha, Černý Most | 2 transfers | |
FlixBus · FlixBus | 8:55 PM Roma, Autostazione Tiburtina | 20h35 | 5:30 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 8:55 PM Roma, Autostazione Tiburtina | 20h25 | 5:20 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 8:55 PM Roma, Autostazione Tiburtina | 27h55 | 12:50 AM Prague, Central Train Station | 2 transfers | |
FlixBus · FlixBus · FlixBus | 8:55 PM Roma, Autostazione Tiburtina | 24h00 | 8:55 PM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:40 PM Roma, Autostazione Tiburtina | 25h35 | 1:15 AM Prague, Central Train Station | 2 transfers | |
| Saturday, April 11 | |||||
FlixBus · FlixBus | 5:30 AM Roma, Autostazione Tiburtina | 22h15 | 3:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 7:30 AM Roma, Autostazione Tiburtina | 21h30 | 5:00 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus · FlixBus | 7:30 AM Roma, Autostazione Tiburtina | 23h25 | 6:55 AM Praha, Na Knížecí | 2 transfers | |
FlixBus · FlixBus · FlixBus | 7:30 AM Roma, Autostazione Tiburtina | 22h00 | 5:30 AM Praha, M. Horákové (Hradčanská) | 2 transfers | |
FlixBus · FlixBus | 7:30 AM Roma, Autostazione Tiburtina | 21h40 | 5:10 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus · FlixBus | 7:30 AM Roma, Autostazione Tiburtina | 26h00 | 9:30 AM Prague, Central Train Station | 2 transfers | |
Find all the dates and times for this journey
Compare prices and tickets Rome to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 10
Apr 11
Apr 12
Apr 13
Apr 14
Apr 15
Apr 16
Apr 17
Apr 18
Apr 19
Apr 20
Apr 21
Apr 22
Apr 23
Apr 24
Apr 25
Apr 26
Apr 27
Apr 28
Apr 29
Apr 30
Why should you book Rome to Prague buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Rome to Prague.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Rome to Prague.
Journey information
Overview: Bus from Rome to Prague
Buses from Rome to Prague run on average 37 times per day, taking around 19h 45m. Cheap bus tickets for this journey start at €55 but you can travel from only €20 by flight.
There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 923 km distance in 20h 10m.
Distance 923 km |
Average bus duration 19h 45m |
Cheapest ticket price €55 |
Buses per day 37 |
Direct buses 2 |
Fastest bus 20h 10m |
First bus 12:10 AM |
Last bus 11:55 PM |
Bus providers: FlixBus from Rome to PragueYou can travel by bus between Rome to Prague with FlixBus for as low as €20. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Rome to Prague
Find answers to the most common questions about traveling from Rome to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Rome to Prague
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
Most popular bus connections from Rome
More options for your journey from Rome to Prague
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