The cheapest and fastest buses from Rome to Lyon
Cheapest price
€44
Average price
€82
Fastest journey
14 h 30 m
Average duration
14 h 56 m
Buses per day
15
Distance
747 km
The best way to find a cheap bus ticket from Rome to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Rome to Lyon will cost around €82 if you buy it on the day, but the cheapest tickets can be found for only €44.
Of the 15 buses that leave Rome for Lyon on Wed, Jun 03, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Jun 03 the direct buses cover the 747 km distance in an average of 14 h 56 m but if you time it right, some buses will get you there in just 14 h 30 m .
On Wed, Jun 03 the slowest buses will take 15 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
2126 · 30928:00 AM16h25Roma, Autostazione Tiburtina12:25 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€441One-way1 transfer
38989:45 PM15h10Roma, Autostazione Tiburtina12:55 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€501One-way0 transfers
47883:20 PM14h45Roma, Autostazione Tiburtina6:05 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€511One-way0 transfers
FlixBus · FlixBus10:45 PM16h20Roma, Autostazione Tiburtina3:05 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€691One-way1 transfer
34927:00 AM14h30Roma, Autostazione Tiburtina9:30 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€701One-way0 transfers
34927:00 AM14h30Roma, Autostazione Tiburtina9:30 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€701One-way0 transfers
47883:20 PM14h45Roma, Autostazione Tiburtina6:05 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€511One-way0 transfers
FlixBus8:50 AM14h55Roma, Autostazione Tiburtina11:45 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€1011One-way0 transfers
38989:45 PM15h10Roma, Autostazione Tiburtina12:55 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€501One-way0 transfers
FlixBus5:25 PM15h20Roma, Autostazione (Metro Anagnina)8:45 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€771One-way0 transfers
Travel Information
Compare bus, flight, and train for Rome to Lyon
Omio recommends booking the bus as it is the most popular option from Rome to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €18. For those with little time consider booking a flight which can get you there in 4h 7m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.7 - 1.9kg. The ticket price range depends on the travel mode: a bus costs an average of €18, and a flight costs an average of €62.
Distance: 747 km
Compare bus with
Most popular Bus | Flight | Train |
|---|---|---|
€44 Average price Cheapest | €161 Average price | €133 Average price |
13h 0m Average total duration 12h 30m Onboard + 30m Additional time* | 7h 7m Average total duration Fastest 4h 7m Onboard + 3h 0m Additional time* | 9h 46m Average total duration 9h 16m Onboard + 30m Additional time* |
0.7 - 1.9kg CO2 emissions Lowest | 2.2 - 4.5kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Rome to Lyon bus times
The table below shows live departures for Rome to Lyon buses for today, Tuesday, June 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 5:05 PM Roma, Autostazione Tiburtina | 15h40 | 8:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 5:25 PM Roma, Autostazione (Metro Anagnina) | 15h20 | 8:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 8:00 PM Roma, Autostazione Tiburtina | 16h00 | 12:00 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
3898 | 9:45 PM Roma, Autostazione Tiburtina | 15h10 | 12:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 10:45 PM Roma, Autostazione Tiburtina | 16h20 | 3:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:35 PM Roma, Autostazione (Metro Anagnina) | 15h30 | 3:05 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 2 transfers | |
| Wednesday, June 3 | |||||
FlixBus · FlixBus | 1:20 AM Roma, Autostazione Tiburtina | 16h50 | 6:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
3492 | 7:00 AM Roma, Autostazione Tiburtina | 14h30 | 9:30 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
2126 · 3092 | 8:00 AM Roma, Autostazione Tiburtina | 16h25 | 12:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 8:50 AM Roma, Autostazione Tiburtina | 14h55 | 11:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 12:20 PM Roma, Autostazione Tiburtina | 19h25 | 7:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
(Rome -> Prague) · (Vienna -> Prague) · (Prague -> Lyon) | 1:00 PM Roma, Autostazione Tiburtina | 49h50 | 2:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 2 transfers | |
FlixBus · FlixBus | 1:05 PM Roma, Autostazione (Metro Anagnina) | 15h50 | 4:55 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Rome to Lyon by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jun 02
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Jun 17
Jun 18
Jun 19
Jun 20
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Jun 22
Why should you book Rome to Lyon buses with Omio?
Why book with Omio vs Itabus?
- Compare with other providers: On Omio, you can not only buy tickets for Itabus, but also compare tickets for the likes of FlixBus, BlaBlaCar Bus or Infobus to find the best option for your trip from Rome to Lyon.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Itabus with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from Rome to Lyon.
Why book with Omio over Checkmybus, Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus, BlaBlaCar Bus or Infobus to find the best option for your trip from Rome to Lyon.
- Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from Rome to Lyon.
Journey information
Overview: Bus from Rome to Lyon
Buses from Rome to Lyon run on average 14 times per day, taking around 12h 30m. Cheap bus tickets for this journey start at €18 if you book in advance.
There are 5 buses per day. The earliest bus runs at 00:04, the last at 23:50. The fastest bus covers the 747 km distance in 14h 30m.
Distance 747 km |
Average bus duration 12h 30m |
Cheapest ticket price €18 |
Buses per day 14 |
Direct buses 5 |
Fastest bus 14h 30m |
First bus 12:04 AM |
Last bus 11:50 PM |
Cheapest Month Feb |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 49 days |
Bus providers: Itabus, FlixBus, BlaBlaCar Bus, BlaBlaCar, Infobus from Rome to LyonYou can travel by bus between Rome to Lyon with Itabus, FlixBus, BlaBlaCar Bus, BlaBlaCar, Infobus for as low as €18. When you search for schedules and tickets, Omio will show you the best journey
Itabus
FlixBus
Infobus
BlaBlaCar Bus
BlaBlaCar
FAQs: Bus from Rome to Lyon
Find answers to the most common questions about traveling from Rome to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Rome to Lyon
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Bistro Lyonnais (0.2 km)
- Fast Food Express (0.3 km).
- Available outside the main entrance.
- Elevators, ramps
- Available on the concourse.
- Bus: C21, C22, S1 Metro: A Train: TER
Most popular bus connections from Rome
More options for your journey from Rome to Lyon
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