The cheapest and fastest buses from Mulhouse to Lyon
Cheapest price
€22
Average price
€28
Fastest journey
3 h 40 m
Average duration
3 h 55 m
Buses per day
10
Distance
292 km
The best way to find a cheap bus ticket from Mulhouse to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mulhouse to Lyon will cost around €28 if you buy it on the day, but the cheapest tickets can be found for only €22.
Of the 10 buses that leave Mulhouse for Lyon on Mon, Mar 30, 10 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Mar 30 the direct buses cover the 292 km distance in an average of 3 h 55 m but if you time it right, some buses will get you there in just 3 h 40 m .
On Mon, Mar 30 the slowest buses will take 4 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
04:00AM3h40Mulhouse07:40AMLyon€221One-way0 transfers
FlixBus07:30AM5h20Mulhouse, Gare Centrale12:50PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€221One-way0 transfers
FlixBus03:05AM5h10Mulhouse, Gare Centrale08:15AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€231One-way0 transfers
FlixBus06:45AM5h45Mulhouse, Gare Centrale12:30PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€231One-way0 transfers
09:00AM5h10Mulhouse02:10PMLyon€251One-way0 transfers
04:00AM3h40Mulhouse07:40AMLyon€221One-way0 transfers
06:40AM3h40Mulhouse10:20AMLyon€271One-way0 transfers
07:30AM3h50Mulhouse11:20AMLyon€391One-way0 transfers
10:40AM4h00Mulhouse02:40PMLyon€371One-way0 transfers
FlixBus12:10AM4h25Mulhouse, Gare Centrale04:35AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€281One-way0 transfers
Travel Information
Compare train, bus, and flight for Mulhouse to Lyon
Omio recommends booking the train as it is the most popular option from Mulhouse to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €13. For those with little time consider booking a train which can get you there in 3h 15m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of €13, and a flight costs an average of €88.
Distance: 292 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€27 Average price Cheapest | €60 Average price | €255 Average price |
4h 53m Average total duration 4h 23m Onboard + 30m Additional time* | 3h 45m Average total duration Fastest 3h 15m Onboard + 30m Additional time* | 11h 37m Average total duration 8h 37m Onboard + 3h 0m Additional time* |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | - CO2 emissions |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Mulhouse to Lyon bus times
The table below shows live departures for Mulhouse to Lyon buses for today, Sunday, March 29. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 9:05 PM Mulhouse, Gare Centrale | 9h10 | 6:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 9:54 PM Mulhouse, Gare Centrale | 10h36 | 8:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 10:10 PM Mulhouse, Gare Centrale | 4h25 | 2:35 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
51510 | 10:10 PM Mulhouse, Gare Routière | 5h00 | 3:10 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| Monday, March 30 | |||||
FlixBus | 1:05 AM Mulhouse, Gare Centrale | 5h10 | 6:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 4:45 AM Mulhouse, Gare Centrale | 5h45 | 10:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus | 5:30 AM Mulhouse, Gare Centrale | 5h20 | 10:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mulhouse to Lyon by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 29
Mar 30
Mar 31
Apr 01
Apr 02
Apr 03
Apr 04
Apr 05
Apr 06
Apr 07
Apr 08
Apr 09
Apr 10
Apr 11
Apr 12
Apr 13
Apr 14
Apr 15
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Apr 17
Apr 18
Why should you book Mulhouse to Lyon buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Mulhouse to Lyon.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Mulhouse to Lyon.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus to find the best option for your trip from Mulhouse to Lyon.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Mulhouse to Lyon.
Journey information
Overview: Bus from Mulhouse to Lyon
Buses from Mulhouse to Lyon run on average 9 times per day, taking around 4h 23m. Cheap bus tickets for this journey start at €13 if you book in advance.
There are 8 buses per day. The earliest bus runs at 00:10, the last at 23:54. The fastest bus covers the 292 km distance in 4h 25m.
Distance 292 km |
Average bus duration 4h 23m |
Cheapest ticket price €13 |
Buses per day 9 |
Direct buses 8 |
Fastest bus 4h 25m |
First bus 00:10 |
Last bus 23:54 |
Bus providers: FlixBus, BlaBlaCar Bus, BlaBlaCar from Mulhouse to LyonYou can travel by bus between Mulhouse to Lyon with FlixBus, BlaBlaCar Bus, BlaBlaCar for as low as €13. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
BlaBlaCar
FAQs: Bus from Mulhouse to Lyon
Find answers to the most common questions about traveling from Mulhouse to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Mulhouse to Lyon
- The place has an entrance that is wheelchair-accessible
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
More options for your journey from Mulhouse to Lyon
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