The cheapest and fastest buses from Venice Mestre to Florence Santa Maria Novella
Cheapest price
€15
Average price
€21
Fastest journey
3 h 45 m
Average duration
4 h 3 m
Buses per day
2
Distance
205 km
The best way to find a cheap bus ticket from Venice Mestre to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Venice Mestre to Florence Santa Maria Novella will cost around €21 if you buy it on the day, but the cheapest tickets can be found for only €15.
Of the 2 buses that leave Venice Mestre for Florence Santa Maria Novella on Fri, Jun 19, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jun 19 the direct buses cover the 205 km distance in an average of 4 h 3 m but if you time it right, some buses will get you there in just 3 h 45 m .
On Fri, Jun 19 the slowest buses will take 4 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus7:15 PM3h45Venezia, Viale Stazione / Via Dante (Mestre Stazione)11:00 PMFirenze, Piazzale Montelungo€151One-way0 transfers
FlixBus9:10 PM4h20Venezia, Viale Stazione / Via Dante (Mestre Stazione)1:30 AMFirenze, Piazzale Montelungo€271One-way0 transfers
FlixBus7:15 PM3h45Venezia, Viale Stazione / Via Dante (Mestre Stazione)11:00 PMFirenze, Piazzale Montelungo€151One-way0 transfers
FlixBus9:10 PM4h20Venezia, Viale Stazione / Via Dante (Mestre Stazione)1:30 AMFirenze, Piazzale Montelungo€271One-way0 transfers
Travel Information
Compare train and bus for Venice Mestre to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Venice Mestre to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the bus with prices starting from €10. For those with little time consider booking a train which can get you there in 3h 24m. The ticket price range depends on the travel mode: a bus costs an average of €10, and a train costs an average of €21.
Distance: 205 km
Compare bus with
| Bus | Most popular Train |
|---|---|
€21 Average price Cheapest | €29 Average price |
4h 17m Average total duration 3h 47m Onboard + 30m Additional time* | 3h 54m Average total duration Fastest 3h 24m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Live departures
Venice Mestre to Florence Santa Maria Novella bus times
The table below shows live departures for Venice Mestre to Florence Santa Maria Novella buses for tomorrow, Friday, June 19. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 7:15 PM Venezia, Viale Stazione / Via Dante (Mestre Stazione) | 3h45 | 11:00 PM Firenze, Piazzale Montelungo | 0 transfersDirect | |
FlixBus | 9:10 PM Venezia, Viale Stazione / Via Dante (Mestre Stazione) | 4h20 | 1:30 AM Firenze, Piazzale Montelungo | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Venice Mestre to Florence Santa Maria Novella by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jun 19
Jun 20
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Why should you book Venice Mestre to Florence Santa Maria Novella buses with Omio?
Why book with Omio vs Itabus?
- Compare with other providers: On Omio, you can not only buy tickets for Itabus, but also compare tickets for the likes of FlixBus or Marino Autolinee to find the best option for your trip from Venice Mestre to Florence Santa Maria Novella.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Itabus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Venice Mestre to Florence Santa Maria Novella.
Why book with Omio over Checkmybus, Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus or Marino Autolinee to find the best option for your trip from Venice Mestre to Florence Santa Maria Novella.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Venice Mestre to Florence Santa Maria Novella.
Journey information
Overview: Bus from Venice Mestre to Florence Santa Maria Novella
Buses from Venice Mestre to Florence Santa Maria Novella run on average 7 times per day, taking around 3h 47m. Cheap bus tickets for this journey start at €10 if you book in advance.
There are 2 buses per day. The earliest bus runs at 11:45, the last at 22:59. The fastest bus covers the 205 km distance in 3h 35m.
Distance 205 km |
Average bus duration 3h 47m |
Cheapest ticket price €10 |
Buses per day 7 |
Direct buses 2 |
Fastest bus 3h 35m |
First bus 11:45 AM |
Last bus 10:59 PM |
Cheapest Month Oct |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Thu |
Bus providers: Itabus, FlixBus, BlaBlaCar, Marino Autolinee from Venice Mestre to Florence Santa Maria NovellaYou can travel by bus between Venice Mestre to Florence Santa Maria Novella with Itabus, FlixBus, BlaBlaCar, Marino Autolinee for as low as €10. When you search for schedules and tickets, Omio will show you the best journey
Itabus
FlixBus
Marino Autolinee
BlaBlaCar
FAQs: Bus from Venice Mestre to Florence Santa Maria Novella
Find answers to the most common questions about traveling from Venice Mestre to Florence Santa Maria Novella by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
Most popular bus connections from Venice Mestre
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