The cheapest and fastest buses from Milan Centrale to Florence Santa Maria Novella
Cheapest price
€7
Average price
€11
Fastest journey
4 h 15 m
Average duration
4 h 24 m
Buses per day
5
Distance
250 km
The best way to find a cheap bus ticket from Milan Centrale to Florence Santa Maria Novella is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Florence Santa Maria Novella will cost around €11 if you buy it on the day, but the cheapest tickets can be found for only €7.
Of the 5 buses that leave Milan Centrale for Florence Santa Maria Novella on Sat, Apr 11, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Apr 11 the direct buses cover the 250 km distance in an average of 4 h 24 m but if you time it right, some buses will get you there in just 4 h 15 m .
On Sat, Apr 11 the slowest buses will take 4 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
9:40 AM4h40Milan Centrale2:20 PMFlorence Santa Maria Novella€71One-way0 transfers
3:40 PM4h20Milan Centrale8:00 PMFlorence Santa Maria Novella€101One-way0 transfers
3:00 PM4h25Milan Centrale7:25 PMFlorence Santa Maria Novella€111One-way0 transfers
9:00 PM4h15Milan Centrale1:15 AMFlorence Santa Maria Novella€121One-way0 transfers
5:30 AM4h20Milan Centrale9:50 AMFlorence Santa Maria Novella€131One-way0 transfers
9:00 PM4h15Milan Centrale1:15 AMFlorence Santa Maria Novella€121One-way0 transfers
5:30 AM4h20Milan Centrale9:50 AMFlorence Santa Maria Novella€131One-way0 transfers
3:40 PM4h20Milan Centrale8:00 PMFlorence Santa Maria Novella€101One-way0 transfers
3:00 PM4h25Milan Centrale7:25 PMFlorence Santa Maria Novella€111One-way0 transfers
9:40 AM4h40Milan Centrale2:20 PMFlorence Santa Maria Novella€71One-way0 transfers
Travel Information
Compare train, bus, and flight for Milan Centrale to Florence Santa Maria Novella
Omio recommends booking the train as it is the most popular option from Milan Centrale to Florence Santa Maria Novella among Omio's users. If you are prioritising price take the bus with prices starting from €7. For those with little time consider booking a train which can get you there in 3h 55m. The ticket price range depends on the travel mode: a bus costs an average of €7, and a flight costs an average of €142.
Distance: 250 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€18 Average price Cheapest | €40 Average price | €147 Average price |
4h 29m Average total duration 3h 59m Onboard + 30m Additional time* | 4h 25m Average total duration Fastest 3h 55m Onboard + 30m Additional time* | 11h 34m Average total duration 8h 34m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Milan Centrale to Florence Santa Maria Novella bus times
The table below shows live departures for Milan Centrale to Florence Santa Maria Novella buses for tomorrow, Friday, April 10. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 5:30 AM Milan Centrale | 4h20 | 9:50 AM Florence Santa Maria Novella | 0 transfersDirect | |
![]() | 3:35 PM Milan Centrale | 5h02 | 8:37 PM Florence Santa Maria Novella | 0 transfersDirect | |
![]() | 6:25 PM Milan Centrale | 5h45 | 12:10 AM Florence Santa Maria Novella | 0 transfersDirect | |
![]() | 8:05 PM Milan Centrale | 6h05 | 2:10 AM Florence Santa Maria Novella | 0 transfersDirect | |
![]() | 9:00 PM Milan Centrale | 4h15 | 1:15 AM Florence Santa Maria Novella | 0 transfersDirect |
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Florence Santa Maria Novella by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Milan Centrale to Florence Santa Maria Novella buses with Omio?
Why book with Omio vs Itabus?
- Compare with other providers: On Omio, you can not only buy tickets for Itabus, but also compare tickets for the likes of FlixBus, BlaBlaCar Bus, Marino Autolinee or Infobus to find the best option for your trip from Milan Centrale to Florence Santa Maria Novella.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Itabus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Milan Centrale to Florence Santa Maria Novella.
Why book with Omio over Checkmybus, Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus, BlaBlaCar Bus, Marino Autolinee or Infobus to find the best option for your trip from Milan Centrale to Florence Santa Maria Novella.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Milan Centrale to Florence Santa Maria Novella.
Journey information
Overview: Bus from Milan Centrale to Florence Santa Maria Novella
Buses from Milan Centrale to Florence Santa Maria Novella run on average 25 times per day, taking around 3h 59m. Cheap bus tickets for this journey start at €7 if you book in advance.
There are 19 buses per day. The earliest bus runs at 05:00, the last at 22:55. The fastest bus covers the 250 km distance in 3h 15m.
Distance 250 km |
Average bus duration 3h 59m |
Cheapest ticket price €7 |
Buses per day 25 |
Direct buses 19 |
Fastest bus 3h 15m |
First bus 5:00 AM |
Last bus 10:55 PM |
Bus providers: Itabus, FlixBus, BlaBlaCar, BlaBlaCar Bus, Marino Autolinee, Infobus, Calanda Viaggi from Milan Centrale to Florence Santa Maria NovellaYou can travel by bus between Milan Centrale to Florence Santa Maria Novella with Itabus, FlixBus, BlaBlaCar, BlaBlaCar Bus, Marino Autolinee, Infobus, Calanda Viaggi for as low as €7. When you search for schedules and tickets, Omio will show you the best journey
Itabus
FlixBus
Marino Autolinee
Infobus
BlaBlaCar Bus
Calanda Viaggi
BlaBlaCar
FAQs: Bus from Milan Centrale to Florence Santa Maria Novella
Find answers to the most common questions about traveling from Milan Centrale to Florence Santa Maria Novella by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Florence Santa Maria Novella, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
Most popular bus connections from Milan Centrale
More options for your journey from Milan Centrale to Florence Santa Maria Novella
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