The cheapest and fastest buses from Venice Santa Lucia to Milan Centrale
Cheapest price
€18
Average price
€75
Fastest journey
2 h 40 m
Average duration
2 h 59 m
Buses per day
12
Distance
243 km
The best way to find a cheap bus ticket from Venice Santa Lucia to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Venice Santa Lucia to Milan Centrale will cost around €75 if you buy it on the day, but the cheapest tickets can be found for only €18.
Of the 12 buses that leave Venice Santa Lucia for Milan Centrale on Sat, Mar 21, 11 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Mar 21 the direct buses cover the 243 km distance in an average of 2 h 59 m but if you time it right, some buses will get you there in just 2 h 40 m .
On Sat, Mar 21 the slowest buses will take 3 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare train, bus, and flight for Venice Santa Lucia to Milan Centrale
Omio recommends booking the train as it is the most popular option from Venice Santa Lucia to Milan Centrale among Omio's users. If you are prioritising price take the train with prices starting from €22. For those with little time consider booking a train which can get you there in 3h 37m. The ticket price range depends on the travel mode: a train costs an average of €22, and a flight costs an average of €104.
Distance: 243 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€83 Average price | €23 Average price Cheapest | €184 Average price |
4h 17m Average total duration 3h 47m Onboard + 30m Additional time* | 4h 7m Average total duration Fastest 3h 37m Onboard + 30m Additional time* | 10h 48m Average total duration 7h 48m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Venice Santa Lucia to Milan Centrale bus times
The table below shows live departures for Venice Santa Lucia to Milan Centrale buses for today, Friday, March 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 1:50 PM Venezia, Tronchetto Vaporetti | 3h55 | 5:45 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 2:10 PM Venezia, Viale Stazione / Via Dante (Mestre Stazione) | 3h35 | 5:45 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 4:00 PM Venezia, Viale Stazione / Via Dante (Mestre Stazione) | 4h10 | 8:10 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 4:05 PM Venezia, Aeroporto Marco Polo di Venezia | 4h10 | 8:15 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 4:30 PM Venezia, Viale Stazione / Via Dante (Mestre Stazione) | 3h45 | 8:15 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 5:10 PM Venezia, Tronchetto Vaporetti | 4h25 | 9:35 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 6:20 PM Venezia, Aeroporto Marco Polo di Venezia | 4h25 | 10:45 PM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 0 transfersDirect | |
FlixBus | 6:20 PM Venezia, Aeroporto Marco Polo di Venezia | 4h55 | 11:15 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 6:50 PM Venezia, Tronchetto Vaporetti | 4h35 | 11:25 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 7:10 PM Venezia, Viale Stazione / Via Dante (Mestre Stazione) | 4h15 | 11:25 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 7:20 PM Venezia, Viale Stazione / Via Dante (Mestre Stazione) | 3h55 | 11:15 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 7:20 PM Venezia, Viale Stazione / Via Dante (Mestre Stazione) | 3h25 | 10:45 PM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 0 transfersDirect | |
FlixBus | 7:45 PM Venezia, Tronchetto Vaporetti | 3h30 | 11:15 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 7:45 PM Venezia, Viale Stazione / Via Dante (Mestre Stazione) | 4h05 | 11:50 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 7:45 PM Venezia, Tronchetto Vaporetti | 3h00 | 10:45 PM Sesto San Giovanni, Piazza Primo Maggio (Stazione ferroviaria) | 0 transfersDirect | |
Regionale 33667 · Treno 16028 effettuato con bus VE096 · Regionale TRENORD 2616 | 11:35 PM Venice Santa Lucia | 7h00 | 6:35 AM Milan Centrale | 2 transfers | |
| Saturday, March 21 | |||||
![]() | 3:05 AM Venice, Piazzale Roma (city center, vaporetto) | 3h20 | 6:25 AM Milano, Piazza Luigi di Savoia | 0 transfersDirect | |
![]() | 3:15 AM Venice, Piazzale Roma (city center, vaporetto) | 3h20 | 6:35 AM Milano, Piazza Luigi di Savoia | 0 transfersDirect | |
![]() | 4:00 AM Venice, Piazzale Roma (city center, vaporetto) | 3h20 | 7:20 AM Milano, Piazza Luigi di Savoia | 0 transfersDirect | |
![]() | 5:00 AM Venice, Piazzale Roma (city center, vaporetto) | 3h20 | 8:20 AM Milano, Piazza Luigi di Savoia | 0 transfersDirect | |
![]() | 6:00 AM Venice, Piazzale Roma (city center, vaporetto) | 3h20 | 9:20 AM Milano, Piazza Luigi di Savoia | 0 transfersDirect | |
![]() | 7:00 AM Venice, Piazzale Roma (city center, vaporetto) | 3h15 | 10:15 AM Milano, Piazza Luigi di Savoia | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Venice Santa Lucia to Milan Centrale by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 20
Mar 21
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Mar 29
Mar 30
Mar 31
Apr 01
Apr 02
Apr 03
Apr 04
Apr 05
Apr 06
Apr 07
Apr 08
Apr 09
Why should you book Venice Santa Lucia to Milan Centrale buses with Omio?
Why book with Omio vs Itabus?
- Compare with other providers: On Omio, you can not only buy tickets for Itabus, but also compare tickets for the likes of GoOpti, FlixBus or BlaBlaCar Bus to find the best option for your trip from Venice Santa Lucia to Milan Centrale.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Itabus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Venice Santa Lucia to Milan Centrale.
Why book with Omio over Checkmybus, Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of GoOpti, FlixBus or BlaBlaCar Bus to find the best option for your trip from Venice Santa Lucia to Milan Centrale.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Venice Santa Lucia to Milan Centrale.
Journey information
Overview: Bus from Venice Santa Lucia to Milan Centrale
Buses from Venice Santa Lucia to Milan Centrale run on average 24 times per day, taking around 3h 47m. Cheap bus tickets for this journey start at €7 if you book in advance.
There are 23 buses per day. The earliest bus runs at 00:00, the last at 23:35. The fastest bus covers the 243 km distance in 3h 0m.
Distance 243 km |
Average bus duration 3h 47m |
Cheapest ticket price €7 |
Buses per day 24 |
Direct buses 23 |
Fastest bus 3h 0m |
First bus 00:00 |
Last bus 23:35 |
Bus providers: Itabus, GoOpti, FlixBus, BlaBlaCar, BlaBlaCar Bus from Venice Santa Lucia to Milan CentraleYou can travel by bus between Venice Santa Lucia to Milan Centrale with Itabus, GoOpti, FlixBus, BlaBlaCar, BlaBlaCar Bus for as low as €7. When you search for schedules and tickets, Omio will show you the best journey
Itabus
FlixBus
BlaBlaCar Bus
GoOpti
BlaBlaCar
FAQs: Bus from Venice Santa Lucia to Milan Centrale
Find answers to the most common questions about traveling from Venice Santa Lucia to Milan Centrale by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- GoOpti
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- GoOpti
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations less than 24 hours before departure are non-refundable.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- GoOpti
- One carry-on bag up to 8kg and one checked bag up to 20kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- GoOpti
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- GoOpti
- Small pets allowed in carriers
- additional fee may apply.
Most popular bus connections from Venice Santa Lucia
More options for your journey from Venice Santa Lucia to Milan Centrale
Here are some other resources that might have the information you need


