The cheapest and fastest trains from Berlin Ostbahnhof to Prague
- Cheapest price on Nov 15
- €32
- Average ticket price on Nov 15
- €60
- Fastest journey on Nov 15
- 4 h 8 m
- Average journey duration on Nov 15
- 4 h 14 m
- Trains on Nov 15
- 18
- Distance
- 278 km
The best way to find a cheap train ticket from Berlin Ostbahnhof to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Berlin Ostbahnhof to Prague will cost around €60 if you buy it on the day, but the cheapest tickets can be found for only €32.
It's difficult to get from Berlin Ostbahnhof to Prague without transferring at least 2 times.
RE 33755 · S 41044 · rj 1716:48 AM 4h37 Berlin Ostbahnhof 11:25 AM Prague hlavní nádraží €32 1 One-way 2 transfers
S3 · 3140 · 18401 · EC 45912:47 AM 8h38 Berlin Ostbahnhof 9:25 AM Prague hlavní nádraží €37 1 One-way 3 transfers
R 75825 · S 41166 · rj 3854:56 PM 4h29 Berlin Ostbahnhof 9:25 PM Prague hlavní nádraží €43 1 One-way 2 transfers
R 75809 · S 4346 · rj 1738:56 AM 4h29 Berlin Ostbahnhof 1:25 PM Prague hlavní nádraží €43 1 One-way 2 transfers
S5 · S2 · RJ 1717:03 AM 4h22 Berlin Ostbahnhof 11:25 AM Prague hlavní nádraží €44 1 One-way 2 transfers
S3 · S41 · RJ 1773:07 PM 4h08 Berlin Ostbahnhof 7:15 PM Prague-Holešovice €88 1 One-way 2 transfers
S5 · S2 · RJ 17511:03 AM 4h12 Berlin Ostbahnhof 3:15 PM Prague-Holešovice €54 1 One-way 2 transfers
S7 · S41 · RJ 3831:10 PM 4h15 Berlin Ostbahnhof 5:25 PM Prague hlavní nádraží €77 1 One-way 2 transfers
S3 · S41 · RJ 3855:07 PM 4h18 Berlin Ostbahnhof 9:25 PM Prague hlavní nádraží €77 1 One-way 2 transfers
R 75813 · S 4358 · rj 17510:56 AM 4h19 Berlin Ostbahnhof 3:15 PM Prague-Holešovice €59 1 One-way 2 transfers
Journey information
Overview: Train from Berlin Ostbahnhof to Prague
Trains from Berlin Ostbahnhof to Prague run on average 10 times per day, taking around 4h 25m. Cheap train tickets for this journey start at €10 if you book in advance.
There are 2 trains per day. The earliest train runs at 06:11, the last at 16:56. The fastest train covers the 278 km distance in 3h 55m.
Distance 278 km |
Average train duration 4h 25m |
Cheapest ticket price €10 |
Trains per day 10 |
Direct trains 2 |
Fastest train 3h 55m |
First train 6:11 AM |
Last train 4:56 PM |
Cheapest Month Feb |
Cheapest Day Tue |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Sun |
Live departures
Berlin Ostbahnhof to Prague train times
The table below shows live departures for Berlin Ostbahnhof to Prague trains for today, Saturday, November 14. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 1:08 PM Berlin Ostbahnhof | 4h06 | 5:14 PM Prague | 0 transfersDirect | |
![]() | 3:08 PM Berlin Ostbahnhof | 4h17 | 7:25 PM Prague | 0 transfersDirect | |
![]() | 3:48 PM Berlin Ostbahnhof | 4h37 | 8:25 PM Prague | 0 transfersDirect | |
![]() | 4:08 PM Berlin Ostbahnhof | 4h17 | 8:25 PM Prague | 0 transfersDirect | |
| Sunday, November 15 | |||||
S3 · 3140 · 18401 · EC 459 | Delayed 12:47 AM Berlin Ostbahnhof | 8h38 | 8:25 AM 8:25 AMPrague hlavní nádraží | 3 transfers | |
Find all the dates and times for this journey
Why should you book Berlin Ostbahnhof to Prague trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of České dráhy or Alibus to find the best option for your trip from Berlin Ostbahnhof to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Berlin Ostbahnhof to Prague.
Why book with Omio over Trainline, Wanderu or Raileurope?
- Compare with other providers: On Omio, you can also compare tickets for the likes of České dráhy or Alibus to find the best option for your trip from Berlin Ostbahnhof to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Berlin Ostbahnhof to Prague.
Train companies: České dráhy, Deutsche Bahn, Alibus from Berlin Ostbahnhof to Prague trainsČeské dráhy, Deutsche Bahn, Alibus trains will get you between Berlin Ostbahnhof and Prague from €10. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Alibus
České dráhy
Companies, tickets, and onboard amenities between Berlin Ostbahnhof and Prague
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
FAQs: Trains from Berlin Ostbahnhof to Prague
Find answers to the most common questions about traveling from Berlin Ostbahnhof to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Berlin Ostbahnhof to Prague
Most Berlin Ostbahnhof to Prague trains use the Berlin Hbf to Praha hlavní nádraží station pair, with some services arriving at Praha-Holesovice. Use this guide to compare Berlin Ostbahnhof and Prague train stations on this route, check city-centre transport, alongside checking practicalities like train station facilities and services.
Getting to Berlin Ostbahnhof from Berlin city centre
Berlin Ostbahnhof is 2 km from Berlin city centre. Public transport options include:
Berlin Ostbahnhof train station facilities and services
Berlin Ostbahnhof has practical services for this route, including Wifi, Lockers, Shopping, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, and Information Desk.
Food and drink
Food options include: Jäger & Lustig, BLOCK HOUSE, Pizza und Pasta, Lang Van II
Wi-Fi and ATMs
Wi-Fi is available at Berlin Ostbahnhof. ATMs are available at Berlin Ostbahnhof.
Tickets and information
Ticket office support is available at Berlin Ostbahnhof. Information desks are available at Berlin Ostbahnhof.
Luggage and lost property
Luggage storage is available at Berlin Ostbahnhof. Lost and found is available at the station.
Parking, taxis and toilets
Available at Berlin Ostbahnhof: Parking, Taxis, WC.
Bike and car services
Available at Berlin Ostbahnhof: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Berlin Ostbahnhof.
Shops, hotels and contact
Nearby hotels include Upstalsboom Hotel Friedrichshain, Armony Hotel, Nu hotel berlin, Holiday Inn Berlin - City East Side.
Getting to Praha hlavní nádraží from Prague city centre
Praha hlavní nádraží is 1 km from Prague city centre. Public transport options include:
Praha hlavní nádraží train station facilities and services
Praha hlavní nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Shower, Lounge, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: Restaurant Fantova Kavárna, Sushi Time
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Praha hlavní nádraží. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Praha hlavní nádraží. Lost and found is available at the station.
Parking, taxis and toilets
Available at Praha hlavní nádraží: Parking, Taxis, WC.
Bike and car services
Available at Praha hlavní nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Praha hlavní nádraží: Elevators, ramps.
Shops, hotels and contact
Nearby hotels include Hotel Esplanade Prague, Falkensteiner Hotel Maria Prag, Hotel City Central.
Getting to Praha-Holesovice from Prague city centre
Praha-Holesovice is 2 km from Prague city centre. Public transport options include:
Praha-Holesovice train station facilities and services
Praha-Holesovice has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: Restaurant Na Kovárně, Cross Club
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Praha-Holesovice. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Praha-Holesovice. Lost and found is available at the station.
Parking, taxis and toilets
Available at Praha-Holesovice: Parking, Taxis, WC.
Bike and car services
Available at Praha-Holesovice: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Praha-Holesovice: Ramps, restrooms.
Shops, hotels and contact
Nearby hotels include Mama Shelter Prague, Plaza Alta Hotel, Hotel Belvedere.
Getting to Praha Masarykovo Nádraží from Prague city centre
Praha Masarykovo Nádraží train station facilities and services
Praha Masarykovo Nádraží has practical services for this route, including Wifi, Lockers, Parking, Dining, ATM, Taxis, Accessibility, WC, Hotel, Lost and Found Office, Ticket Office, Bike Parking, Bike Rental, Car Rental, Information Desk, and Luggage Carts.
Food and drink
Food options include: Restaurant Kotleta, Café Imperial
Wi-Fi and ATMs
Free. ATMs are available in the train station.
Tickets and information
Ticket office support is available at Praha Masarykovo Nádraží. Information desks are located in the main hall.
Luggage and lost property
Luggage storage is available at Praha Masarykovo Nádraží. Lost and found is available at the station.
Parking, taxis and toilets
Available at Praha Masarykovo Nádraží: Parking, Taxis, WC.
Bike and car services
Available at Praha Masarykovo Nádraží: Bike Parking, Bike Rental, Car Rental.
Accessibility
Accessibility facilities are available at Praha Masarykovo Nádraží: Ramps.
Shops, hotels and contact
Nearby hotels include Hotel Kings Court, Grand Hotel Bohemia, Hotel Paris Prague.
More options for your journey from Berlin Ostbahnhof to Prague
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