The cheapest and fastest trains from Luxembourg to Prague
Cheapest price
€70
Average price
€186
Fastest journey
11 h 53 m
Average duration
12 h 1 m
Trains per day
14
Distance
596 km
The best way to find a cheap train ticket from Luxembourg to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Luxembourg to Prague will cost around €186 if you buy it on the day, but the cheapest tickets can be found for only €70.
It's difficult to get from Luxembourg to Prague without transferring at least 3 times.
Bus 82142 · ICE 9555 · ICE 590 · 165015:00 PM16h10Luxembourg station9:10 AMPrague hlavní nádraží€701One-way6 transfers
Bus 82154 · ICE 9557 · 4542 · EC 4597:10 PM14h15Luxembourg station9:25 AMPrague hlavní nádraží€701One-way3 transfers
RE 5123 · 4265 · ICE 1657 · S12:33 PM17h37Luxembourg station8:10 AMPrague hlavní nádraží€861One-way5 transfers
RE 5117 · ICE 1229 · ICE 596 · IC 204711:33 AM11h58Luxembourg station11:31 PMPrague hlavní nádraží€1311One-way4 transfers
RE 5113 · 4106 · ICE 517+
3639:33 AM12h49Luxembourg station10:22 PMPrague hlavní nádraží€1511One-way3 transfers
RE 5119 · R 4263 · ICE 1655 · NJ 45712:33 PM11h53Luxembourg station12:26 AMPrague hlavní nádraží€2111One-way3 transfers
Bus 82122 · ICE 1561 · S1 · 280129:15 AM11h55Luxembourg station9:10 PMPrague hlavní nádraží€2181One-way5 transfers
RE 5117 · ICE 1229 · ICE 596 · IC 204711:33 AM11h58Luxembourg station11:31 PMPrague hlavní nádraží€1311One-way4 transfers
Bus 82122 · ICE 1561 · RJ 385+
TGV 95519:15 AM12h10Luxembourg station9:25 PMPrague hlavní nádraží€1981One-way3 transfers
Bus 82122 · ICE 1561 · RJ 393+
TGV 95519:15 AM12h10Luxembourg station9:25 PMPrague hlavní nádraží€2341One-way3 transfers
Travel Information
Compare bus, train, and flight for Luxembourg to Prague
Omio recommends booking the bus as it is the most popular option from Luxembourg to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €41. For those with little time consider booking a flight which can get you there in 2h 12m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of €41, and a flight costs an average of €133.
Distance: 596 km
Compare train with
| Train | Most popular Bus | Flight |
|---|---|---|
€114 Average price | €58 Average price Cheapest | €234 Average price |
12h 4m Average total duration 11h 34m Onboard + 30m Additional time* | 11h 11m Average total duration 10h 41m Onboard + 30m Additional time* | 5h 12m Average total duration Fastest 2h 12m Onboard + 3h 0m Additional time* |
0.2 - 0.5kg CO2 emissions Lowest | 0.6 - 1.5kg CO2 emissions | 1.8 - 3.6kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Luxembourg to Prague train times
The table below shows live departures for Luxembourg to Prague trains for today, Sunday, May 31. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
RE 5137 · 4137 · IC 60403 · ICE 827 | On time 9:33 PM Luxembourg station | 14h48 | 12:21 PM Prague hlavní nádraží | 5 transfers | |
RE 5139 · 4134 · 29501 · ICE 523 | On time 10:33 PM Luxembourg station | 15h48 | 2:21 PM Prague hlavní nádraží | 5 transfers | |
RE 5139 · 4134 · 29501 · ICE 1555 | On time 10:33 PM Luxembourg station | 16h42 | 3:15 PM Prague-Holešovice | 5 transfers | |
| Monday, June 1 | |||||
R 5107 · ICE 25 · R 3567 · EC 359 | 6:10 AM Luxembourg station | 12h11 | 6:21 PM Prague hlavní nádraží | 3 transfers | |
RE 5109 · ICE 1225 · R 3571 · EC 361 | On time 7:33 AM Luxembourg station | 12h48 | 8:21 PM Prague hlavní nádraží | 3 transfers | |
RE 5111 · R 4259 · ICE 1651 · rj 385 | On time 8:33 AM Luxembourg station | 12h52 | 9:25 PM Prague hlavní nádraží | 3 transfers | |
Bus 82122 · ICE 1561 · RJ 393+ TGV 9551 | On time 9:15 AM Luxembourg station | 12h10 | 9:25 PM Prague hlavní nádraží | 3 transfers | |
Bus 82122 · ICE 1561 · RJ 385+ TGV 9551 | On time 9:15 AM Luxembourg station | 12h10 | 9:25 PM Prague hlavní nádraží | 3 transfers | |
Bus 82122 · ICE 1561 · S1 · 28012 | On time 9:15 AM Luxembourg station | 11h55 | 9:10 PM Prague hlavní nádraží | 5 transfers | |
RE 5113 · 4106 · ICE 517+ 363 | On time 9:33 AM Luxembourg station | 12h49 | 10:22 PM Prague hlavní nádraží | 3 transfers | |
RE 5117 · ICE 1229 · ICE 596 · IC 2047 | On time 11:33 AM Luxembourg station | 11h58 | 11:31 PM Prague hlavní nádraží | 4 transfers | |
RE 5119 · R 4263 · ICE 1655 · NJ 457 | On time 12:33 PM Luxembourg station | 11h53 | 12:26 AM Prague hlavní nádraží | 3 transfers | |
RE 5123 · 4265 · ICE 1657 · S1 | On time 2:33 PM Luxembourg station | 17h37 | 8:10 AM Prague hlavní nádraží | 5 transfers | |
RE 5127 · ICE 1640 · EC 459 | On time 4:33 PM Luxembourg station | 16h52 | 9:25 AM Prague hlavní nádraží | 2 transfers | |
Bus 82142 · ICE 9555 · ICE 590 · 16501 | On time 5:00 PM Luxembourg station | 16h10 | 9:10 AM Prague hlavní nádraží | 6 transfers | |
Bus 82154 · ICE 9557 · 4542 · EC 459 | On time 7:10 PM Luxembourg station | 14h15 | 9:25 AM Prague hlavní nádraží | 3 transfers | |
RE 5135 · IC 60403 · ICE 698 · IC 2449 | On time 8:33 PM Luxembourg station | 14h52 | 11:25 AM Prague hlavní nádraží | 4 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Luxembourg to Prague by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 31
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Why should you book Luxembourg to Prague trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of České dráhy or alex-Länderbahn und Vogtlandbahn-GmbH to find the best option for your trip from Luxembourg to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Luxembourg to Prague.
Why book with Omio over Trainline, Wanderu or Raileurope?
- Compare with other providers: On Omio, you can also compare tickets for the likes of České dráhy or alex-Länderbahn und Vogtlandbahn-GmbH to find the best option for your trip from Luxembourg to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Luxembourg to Prague.
How far in advance should I book train tickets from Luxembourg to Prague?
Journey information
Overview: Train from Luxembourg to Prague
Trains from Luxembourg to Prague run on average 6 times per day, taking around 11h 34m. Cheap train tickets for this journey start at €59 but you can travel from only €41 by bus.
The earliest train runs at 00:30, the last at 23:54. The fastest train covers the 596 km distance in 11h 42m.
Distance 596 km |
Average train duration 11h 34m |
Cheapest ticket price €59 |
Trains per day 6 |
Fastest train 11h 42m |
First train 12:30 AM |
Last train 11:54 PM |
Cheapest Month Jul |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 63 days |
Train companies: Deutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH from Luxembourg to Prague trainsDeutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH trains will get you between Luxembourg and Prague from €41. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
alex-Länderbahn und Vogtlandbahn-GmbH
České dráhy
FAQs: Trains from Luxembourg to Prague
Find answers to the most common questions about traveling from Luxembourg to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Luxembourg to Prague
- 5:00 AM - 11:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week from 5:00 a.m. to 1:00 a.m. Departures can be made outside of opening hours. You can access the car park at 4 rue de Compiègne as well as at 112 rue Maubeuge.
- Brasserie Schuman
- Vapiano Luxembourg Gare
- Outside the main entrance.
- Elevators, ramps, restrooms.
- €1
- Hotel Empire
- Hotel Carlton
- Park Inn by Radisson Luxembourg City
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-9 for trains to France, Belgium, Germany, and regional destinations
- Hall 2: Tram connections
- Bus: Several lines available
- Tram: Line T1
- Train: National and international connections
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
- Restaurant Fantova Kavárna
- Sushi Time
- Outside the main entrance.
- Elevators, ramps.
- CZK 10
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
- Cost CZK 100
- Located in the main hall
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with several public parking options.
- Restaurant Kotleta
- Café Imperial
- Outside the main entrance.
- Ramps.
- CZK 10
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Partyzánská street.
- Restaurant Na Kovárně
- Cross Club
- Outside the main entrance.
- Ramps, restrooms.
- CZK 10
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
- Located in the main hall
- Avis
- Budget
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
Most popular train connections from Luxembourg
More options for your journey from Luxembourg to Prague
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