The cheapest and fastest trains from Düsseldorf to Prague
Cheapest price
€89
Average price
€177
Fastest journey
8 h 59 m
Average duration
9 h
Trains per day
12
Distance
553 km
The best way to find a cheap train ticket from Düsseldorf to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Düsseldorf to Prague will cost around €177 if you buy it on the day, but the cheapest tickets can be found for only €89.
It's difficult to get from Düsseldorf to Prague without transferring at least 2 times.
FlixTrain+
FlixBus4:38 PM12h22Düsseldorf Hbf5:00 AMPrague, Central Train Station€891One-way1 transfer
FlixTrain+
FlixBus4:38 PM12h02Düsseldorf Hbf4:40 AMPraha, ÚAN Florenc€891One-way1 transfer
FlixTrain+
FlixBus12:38 PM14h12Düsseldorf Hbf2:50 AMPrague, Central Train Station€931One-way1 transfer
ICE 849 · rj 38511:50 AM9h35Düsseldorf Hbf9:25 PMPrague hlavní nádraží€1291One-way1 transfer
ICE 847 · rj 1779:50 AM9h25Düsseldorf Hbf7:15 PMPrague-Holešovice€1291One-way1 transfer
ICE 621 · 3569+
3599:22 AM8h59Düsseldorf Hbf6:21 PMPrague hlavní nádraží€1921One-way2 transfers
ICE 621 · R 3569 · EC 3599:22 AM8h59Düsseldorf Hbf6:21 PMPrague hlavní nádraží€2821One-way2 transfers
ICE 629 · 3577+
3631:22 PM9h00Düsseldorf Hbf10:22 PMPrague hlavní nádraží€2171One-way2 transfers
ICE 625 · 3499+
36111:19 AM9h02Düsseldorf Hbf8:21 PMPrague hlavní nádraží€2171One-way2 transfers
ICE 625 · R 3499 · EC 36111:19 AM9h02Düsseldorf Hbf8:21 PMPrague hlavní nádraží€2821One-way2 transfers
Travel Information
Compare train, bus, and flight for Düsseldorf to Prague
Omio recommends booking the train as it is the most popular option from Düsseldorf to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €30. For those with little time consider booking a flight which can get you there in 2h 0m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of €30, and a flight costs an average of €44.
Distance: 553 km
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
€74 Average price | €152 Average price | €48 Average price Cheapest |
9h 50m Average total duration 9h 20m Onboard + 30m Additional time* | 5h 0m Average total duration Fastest 2h 0m Onboard + 3h 0m Additional time* | 10h 24m Average total duration 9h 54m Onboard + 30m Additional time* |
0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.3kg CO2 emissions | 0.6 - 1.4kg CO2 emissions |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Düsseldorf to Prague train times
The table below shows live departures for Düsseldorf to Prague trains for today, Thursday, April 9. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
ICE 629 · 3577+ 363 | On time 11:22 AM Düsseldorf Hbf | 9h00 | 8:22 PM Prague hlavní nádraží | 2 transfers | |
FlixTrain+ FlixBus | 2:38 PM Düsseldorf Hbf | 12h22 | 3:00 AM Prague, Central Train Station | 1 transfer | |
FlixTrain+ FlixBus | 2:38 PM Düsseldorf Hbf | 12h02 | 2:40 AM Praha, ÚAN Florenc | 1 transfer | |
| Friday, April 10 | |||||
ICE 621 · R 3569 · EC 359 | On time 7:22 AM Düsseldorf Hbf | 8h59 | 4:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 621 · 3569+ 359 | On time 7:22 AM Düsseldorf Hbf | 8h59 | 4:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 847 · RJ 177 | On time 7:50 AM Düsseldorf Hbf | 9h25 | 5:15 PM Prague-Holešovice | 1 transfer | |
ICE 847 · rj 177 | On time 7:50 AM Düsseldorf Hbf | 9h25 | 5:15 PM Prague-Holešovice | 1 transfer | |
ICE 625 · R 3499 · EC 361 | 9:19 AM Düsseldorf Hbf | 9h02 | 6:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 625 · 3499+ 361 | 9:19 AM Düsseldorf Hbf | 9h02 | 6:21 PM Prague hlavní nádraží | 2 transfers | |
ICE 849 · rj 385 | 9:50 AM Düsseldorf Hbf | 9h35 | 7:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 849 · RJ 385 | On time 9:50 AM Düsseldorf Hbf | 9h35 | 7:25 PM Prague hlavní nádraží | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Düsseldorf to Prague by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 09
Apr 10
Apr 11
Apr 12
Apr 13
Apr 14
Apr 15
Apr 16
Apr 17
Apr 18
Apr 19
Apr 20
Apr 21
Apr 22
Apr 23
Apr 24
Apr 25
Apr 26
Apr 27
Apr 28
Apr 29
Why should you book Düsseldorf to Prague trains with Omio?
Why book with Omio vs Deutsche Bahn?
- Compare with other providers: On Omio, you can not only buy tickets for Deutsche Bahn, but also compare tickets for the likes of České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH or FlixTrain to find the best option for your trip from Düsseldorf to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Deutsche Bahn with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Düsseldorf to Prague.
Why book with Omio over Trainline, Wanderu or Raileurope?
- Compare with other providers: On Omio, you can also compare tickets for the likes of České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH or FlixTrain to find the best option for your trip from Düsseldorf to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Düsseldorf to Prague.
How far in advance should I book train tickets from Düsseldorf to Prague?
Journey information
Overview: Train from Düsseldorf to Prague
Trains from Düsseldorf to Prague run on average 14 times per day, taking around 9h 20m. Cheap train tickets for this journey start at €36 but you can travel from only €30 by bus.
The earliest train runs at 00:10, the last at 23:54. The fastest train covers the 553 km distance in 8h 27m.
Distance 553 km |
Average train duration 9h 20m |
Cheapest ticket price €36 |
Trains per day 14 |
Fastest train 8h 27m |
First train 12:10 AM |
Last train 11:54 PM |
Train companies: Deutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH, FlixTrain from Düsseldorf to Prague trainsDeutsche Bahn, České dráhy, alex-Länderbahn und Vogtlandbahn-GmbH, FlixTrain trains will get you between Düsseldorf and Prague from €30. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
alex-Länderbahn und Vogtlandbahn-GmbH
FlixTrain
České dráhy
FAQs: Trains from Düsseldorf to Prague
Find answers to the most common questions about traveling from Düsseldorf to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Düsseldorf to Prague
- Monday: 07:00 - 21:00
- Tuesday: 07:00 - 21:00
- Wednesday: 07:00 - 21:00
- Thursday: 07:00 - 21:00
- Friday: 07:00 - 21:00
- Saturday: 09:00 - 21:00
- Sunday: 09:00 - 21:00
- Zaxopondeiva Cafe
- Lauren's Cafe
- China Imbiss
- Fu chu yuan
- Hotel Lindenhof
- Hotel Batavia
- Sir Astor
- Lady Astor
- Fu chu yuan
- Taj Mahal
- Hai Xian
- To1980
- Hotel Batavia
- Hotel Ko
- Hotel Burns
- Hotel Düsseldorf Mitte
- Zur Pfeffermühle
- Pizzeria Da Gino
- Rohbau
- Grindhouse Homemade Burgers
- Novum Hotel Maxim Düsseldorf City
- Günnewig Hotel Esplanade
- Novum Hotel Flora
- Hotel Niku
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
- Restaurant Fantova Kavárna
- Sushi Time
- Outside the main entrance.
- Elevators, ramps.
- CZK 10
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
- Cost CZK 100
- Located in the main hall
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with several public parking options.
- Restaurant Kotleta
- Café Imperial
- Outside the main entrance.
- Ramps.
- CZK 10
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Partyzánská street.
- Restaurant Na Kovárně
- Cross Club
- Outside the main entrance.
- Ramps, restrooms.
- CZK 10
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
- Located in the main hall
- Avis
- Budget
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
Most popular train connections from Düsseldorf
More options for your journey from Düsseldorf to Prague
Here are some other resources that might have the information you need

