Karlsruhe to Prague train with Deutsche Bahn (RE,IC,EC,ICE)

Wed, Nov 05
+ Add return
Deutsche Bahn
Alex
Regionale
SNCF TER
Regiojet
1,000+ travel companies
Deutsche Bahn
Alex
Regionale
SNCF TER
Regiojet
1,000+ travel companies
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The cheapest and fastest trains from Karlsruhe to Prague

Showing times and prices for Nov 05

Cheapest price

€96

Average price

€174

Fastest journey

8 h 54 m

Average duration

9 h 15 m

Trains per day

10

Distance

452 km

Cheap tickets

The best way to find a cheap train ticket from Karlsruhe to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Karlsruhe to Prague will cost around €174 if you buy it on the day, but the cheapest tickets can be found for only €96.

Fast trains

It's difficult to get from Karlsruhe to Prague without transferring at least 2 times.

Deutsche BahnICE 9571 · ICE 513+Alex359
09:28AM8h54
Karlsruhe Hbf
06:22PMPrague hlavní nádraží
961One-way
2 transfers
Deutsche BahnRE 19673 · ICE 591 · RE 4068+waldbahn - Länderbahn und Regental Bahnbetriebs-GmbH83927
08:06AM9h44
Karlsruhe Hbf
05:50PMPraha-Smíchov
961One-way
6 transfers
Deutsche BahnICE 267 · RE 26783 · Bus EV · RE 5287
08:05AM9h17
Karlsruhe Hbf
05:22PMPrague hlavní nádraží
1381One-way
4 transfers
Deutsche BahnIC 2067 · ICE 91+Alex359
09:05AM9h17
Karlsruhe Hbf
06:22PMPrague hlavní nádraží
1381One-way
2 transfers
Deutsche BahnICE 267+Alex359
08:05AM10h17
Karlsruhe Hbf
06:22PMPrague hlavní nádraží
1451One-way
1 transfer

Travel Information

Compare bus and train for Karlsruhe to Prague

Omio recommends booking the train as it is the most popular option from Karlsruhe to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €26. For those with little time consider booking a bus which can get you there in 7h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €26, and a train costs an average of €28.

Distance: 452 km

Compare train with

Most popular
Train
Bus

€79

Average price

€43

Average price

Cheapest

9h 25m

Average total duration

8h 55m

Onboard

+

30m

Additional time*

7h 49m

Average total duration

Fastest

7h 19m

Onboard

+

30m

Additional time*

0.1 - 0.4kg

CO2 emissions

Lowest

0.5 - 1.1kg

CO2 emissions

Deutsche Bahn

Most popular train company

FlixBus

Most popular bus company

Direct Options

Direct Options

Additional time: Average total travel duration to departure point, security checks and transfers.

Live departures

Karlsruhe to Prague train times

Showing trains for today, Tuesday, November 4
Last updated at 8:04 PM
Last updated at 8:04 PM

ProviderDepartsDurationArrivesTransfers
Tickets
deutsche_bahn9:07 PM Karlsruhe
10h16
7:23 AM Prague0 transfersDirect
Wednesday, November 5
deutsche_bahnICE 374 · ICE 1557 · BUS 10175 · EC 175
On time
7:00 AM Karlsruhe Hbf
9h23
4:23 PM Prague hlavní nádraží
3 transfers
czechrailwayICE 374 · ICE 1557 · EC 10175 · EC 175
On time
7:00 AM Karlsruhe Hbf
9h23
4:23 PM Prague hlavní nádraží
3 transfers
czechrailwayICE 267 · EC 359
On time
7:05 AM Karlsruhe Hbf
10h17
5:22 PM Prague hlavní nádraží
1 transfer
deutsche_bahnICE 267 · RE 26783 · Bus EV · RE 5287
On time
7:05 AM Karlsruhe Hbf
9h17
4:22 PM Prague hlavní nádraží
4 transfers
czechrailwayICE 267 · RE 4068 · R 83927 · Os 7551
On time
7:05 AM Karlsruhe Hbf
9h45
4:50 PM Praha-Smíchov
4 transfers
deutsche_bahnICE 267+alexlv359
On time
7:05 AM Karlsruhe Hbf
10h17
5:22 PM Prague hlavní nádraží
1 transfer
deutsche_bahnRE 19673 · ICE 591 · RE 4068+waldbahn83927
On time
7:06 AM Karlsruhe Hbf
9h44
4:50 PM Praha-Smíchov
6 transfers
deutsche_bahnIC 2067 · ICE 91+alexlv359
On time
8:05 AM Karlsruhe Hbf
9h17
5:22 PM Prague hlavní nádraží
2 transfers
deutsche_bahnICE 9571 · ICE 513+alexlv359
Delayed
8:45 AM 8:28 AMKarlsruhe Hbf
8h54
5:22 PM Prague hlavní nádraží
2 transfers
czechrailwayICE 372 · ICE 1559 · EC 10177 · EC 1779:00 AM Karlsruhe Hbf
9h23
6:23 PM Prague hlavní nádraží3 transfers

This is the last train of the day.

Find all the dates and times for this journey

Compare prices and tickets Karlsruhe to Prague by bus or train

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How far in advance should I book train tickets from Karlsruhe to Prague?

The best time to book your train from Karlsruhe to Prague is 63 days before departure. See how prices for trains change on the Karlsruhe to Prague route.
Prices are for one-way tickets for one passenger from Karlsruhe to Prague per month. Insights are sourced from fares found by Omio users in the last 12 months. Current prices may differ as prices vary depending on the time of day, class or how far in advance you book your train from Karlsruhe to Prague.

Journey information

Overview: Train from Karlsruhe to Prague

GermanyGermany
CzechiaCzechia
Icon of train
Trains from Karlsruhe to Prague run on average 8 times per day, taking around 8h 55m. Cheap train tickets for this journey start at €28 but you can travel from only €26 by bus.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €26
Distance
452 km
Average train duration
8h 55m
Cheapest ticket price
€28
Trains per day
8
Fastest train
8h 16m
First train
00:19
Last train
23:50
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €26

Train companies: Deutsche Bahn, Alex from Karlsruhe to Prague trainsDeutsche Bahn, Alex trains will get you between Karlsruhe and Prague from €26. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Deutsche Bahn

About
Deutsche Bahn (DB) is Germany’s main train operator, running around 40,000 domestic and international services each day. Its fleet includes a variety of train types: high-speed ICE (Intercity Express) trains, reaching up to 300 km/h; IC (Intercity) and EC (EuroCity) trains for long-distance travel; and IRE (Interregio-Express), RE (Regional Express), and RB (Regionalbahn) services for regional and local connections. While bathrooms are standard on all trains, amenities such as onboard restaurants and free Wi-Fi are available only on certain train types and routes. DB offers a wide range of fares, including Super Saver, Saver, and Flexible tickets, along with discount cards like the BahnCard 25, 50, and 100. Additional options include single tickets, day tickets, and group tickets. Popular routes include Berlin–Munich, Hamburg–Frankfurt, Cologne–Stuttgart, Berlin–Dresden, and Hamburg–Cologne, as well as numerous regional services across Germany.
Luggage & cancellation policy
Average Duration
8h 16m
Cheapest Price
€28
Deutsche Bahn frequency
4 a day
Luggage included
Passengers are allowed to bring hand luggage and one additional larger item free of charge, provided they can carry it themselves
Luggage storage
Luggage can be stored in overhead racks, under the seat, or in designated luggage areas near the doors or in the middle of the carriage.
Cancellation Policy
Tickets can be canceled based on their fare conditions as mentioned in what type of train tickets are refundable?
Refund
If DB cancels a train, passengers are entitled to a full refund of the ticket price.
Amenities on board the train
Wifi
Food sold onboard
Most ICE and many IC/EC trains have:
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Seat reservation
Second Class:
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Toilets
USB plugs
Accessibility
DB trains are equipped with facilities for passengers with reduced mobility, including wheelchair spaces, accessible restrooms, and assistance services.
Pets
Small pets (e.g. cats, small dogs, etc.):
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Quiet zone

Alex

About
agilis is a railway company operating regional trains based in Regensburg in Bavaria since 2010. It operates in the German state of Bavaria connecting cities like Ulm, Ingolstadt, Regensburg and Plattling. They offer single tickets and comfortable trains with some popular routes covering Ulm to Regensburg, Neumarkt to Passau and Ingolstadt to Plattling.
Luggage & cancellation policy
Alex frequency
4 a day
Luggage included
One piece of hand luggage and one larger piece included
Luggage storage
Overhead racks and designated luggage areas
Cancellation Policy
Cancellation possible according to fare conditions
Refund
Full refund for canceled services
Amenities on board the train
Wifi
Food sold onboard
Snack and beverage service available on some routes
Seat reservation
Seat reservations available for additional fee
Toilets
USB plugs
Accessibility
Wheelchair spaces available, assistance for boarding/alighting
Pets
Small pets in carriers travel free, larger dogs require ticket and muzzle
Quiet zone

FAQs: Trains from Karlsruhe to Prague

FAQs: Travel by train from Karlsruhe to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Karlsruhe to Prague.
FAQs
The first train from Karlsruhe to Prague leaves at 07: 00. Plan your trip with the Journey Planner   from Omio.
The last train from Karlsruhe to Prague leaves at 22: 07.
When taking a train from Karlsruhe to Prague, you can count on Alex or Deutsche Bahn for the best way to get you to Prague. You can also check all possible train providers who offer a service between Karlsruhe and Prague and compare the amenities they offer before buying a train ticket.
No, there are no night trains, the latest train for this route is 22: 07.

When departing from Karlsruhe, you have various train station options to start your trip from including Karlsruhe Hbf, Karlsruhe Bahnhofsvorplatz and Karlsruhe-Durlach station. When arriving in Prague, you can end your route in train stations like Prague hlavní nádraží, Prague-Holešovice and Praha-Kačerov.

Passengers board the train most frequently from Karlsruhe Hbf, which is located around 1.5 miles (2.4 km) away from the city centre, and they get off the train at Prague hlavní nádraží, located 1.8 miles (2.9 km) away from the city centre.

The cheapest month to travel from Karlsruhe to Prague by train is December.
Yes, you can take a coach to Prague from Karlsruhe.

popular train stations

Popular train stations from Karlsruhe to Prague

Karlsruhe
Prague
The major train station for departures in Karlsruhe is Karlsruhe Hbf. Find all the information you need to know about services, amenities and connections at Karlsruhe Hbf for your trip from Karlsruhe to Prague.
Amenities at train station
WifiWifi
LockersLockers
ShoppingShopping
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
LoungeLounge
Lost and Found OfficeLost and Found Office
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
information
ticketOfficeHours
Ticket Office Hours
  • Monday: 06:30 - 21:00
  • Tuesday: 06:30 - 21:00
  • Wednesday: 06:30 - 21:00
  • Thursday: 06:30 - 21:00
  • Friday: 06:30 - 21:00
  • Saturday: 08:00 - 19:00
  • Sunday: 09:00 - 20:00
ticketOfficeHours
Distance to city center
1 km
Dining
Dining
  • Vinarte
  • Am Tiergarten
  • Panorama
  • Alter Brauhof
Hotel
Hotel
  • Hotel Barbarossa
  • Hotel Avisa
  • Am Tiergarten
  • Aparthotel Aijana
Karlsruhe WestWifiLockersShoppingParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
Amenities at train station
WifiWifi
LockersLockers
ShoppingShopping
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
LoungeLounge
Lost and Found OfficeLost and Found Office
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
information
ticketOfficeHours
Distance to city center
1 km
Dining
Dining
  • Beim Schupi
  • Rosenstüble 2.0
  • Saloniki
  • Rote Taube
Hotel
Hotel
  • Beim Schupi
Karlsruhe-DurlachWifiLockersShoppingParkingDiningATMTaxisAccessibilityWCHotelLoungeLost and Found OfficeTicket OfficeBike ParkingBike RentalCar RentalInformation Desk
Amenities at train station
WifiWifi
LockersLockers
ShoppingShopping
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
LoungeLounge
Lost and Found OfficeLost and Found Office
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
information
ticketOfficeHours
Ticket Office Hours
  • Monday: 08:00 13:30 - 12:30 18:00
  • Tuesday: 08:00 13:30 - 12:30 18:00
  • Wednesday: 08:00 13:30 - 12:30 18:00
  • Thursday: 08:00 13:30 - 12:30 18:00
  • Friday: 08:00 13:30 - 12:30 18:00
  • Saturday: 09:00 - 13:00
ticketOfficeHours
Distance to city center
5 km
Dining
Dining
  • Hubraum
  • Vogel Hausbräu Durlach
  • Asia Gourmet
  • Borsalino
Hotel
Hotel
  • Hotel Große Linde
  • Zum Erwin
  • Der Blaue Reiter
Karlsruhe, Hbf SüdausgangAccessibility
Amenities at train station
AccessibilityAccessibility
information
phone
Phone Number
ticketOfficeHours
Distance to city center
1 km

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