The cheapest and fastest trains from Karlsruhe to Prague
Cheapest price
€91
Average price
€134
Fastest journey
8 h 16 m
Average duration
8 h 27 m
Trains per day
9
Distance
452 km
The best way to find a cheap train ticket from Karlsruhe to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Prague will cost around €134 if you buy it on the day, but the cheapest tickets can be found for only €91.
It's difficult to get from Karlsruhe to Prague without transferring at least 3 times.
ICE 202 · ICE 513+
359
ICE 202 · ICE 692 · IC 2443 · rj 383
ICE 374 · ICE 1559 · rj 177
ICE 202 · ICE 692 · IC 2443 · RJ 383
ICE 267 · 89685 · 3565+
357
ICE 267 · 89685 · 3565+
357
ICE 267 · R 89685 · R 3565 · EC 357
ICE 202 · ICE 692 · IC 2443 · rj 383
ICE 202 · ICE 692 · IC 2443 · RJ 383
R 19009 · R 88617 · R 3569 · EC 359Travel Information
Compare bus and train for Karlsruhe to Prague
Omio recommends booking the train as it is the most popular option from Karlsruhe to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €26. For those with little time consider booking a bus which can get you there in 7h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €26, and a train costs an average of €28.
Distance: 452 km
Compare train with
Most popular Train | Bus |
|---|---|
€79 Average price | €43 Average price Cheapest |
9h 25m Average total duration 8h 55m Onboard + 30m Additional time* | 7h 49m Average total duration Fastest 7h 19m Onboard + 30m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.1kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Karlsruhe to Prague train times
The table below shows live departures for Karlsruhe to Prague trains for today, Tuesday, February 3. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
ICE 202 · ICE 692 · IC 2443 · rj 383 | Delayed 8:00 AM 7:59 AMKarlsruhe Hbf | 8h26 | 4:25 PM Prague hlavní nádraží | 3 transfers | |
ICE 202 · ICE 692 · IC 2443 · RJ 383 | Delayed 8:00 AM 7:59 AMKarlsruhe Hbf | 8h26 | 4:25 PM Prague hlavní nádraží | 3 transfers | |
ICE 374 · ICE 1559 · rj 177 | Delayed 9:00 AM 8:59 AMKarlsruhe Hbf | 9h16 | 6:15 PM Prague-Holešovice | 2 transfers | |
ICE 374 · ICE 1559 · RJ 177 | Delayed 9:00 AM 8:59 AMKarlsruhe Hbf | 9h16 | 6:15 PM Prague-Holešovice | 2 transfers | |
ICE 798 · RJ 385 | On time 9:40 AM Karlsruhe Hbf | 10h45 | 8:25 PM Prague hlavní nádraží | 1 transfer | |
ICE 200 · ICE 690 · IC 2441 · RJ 177 | On time 9:59 AM Karlsruhe Hbf | 8h16 | 6:15 PM Prague-Holešovice | 3 transfers | |
IC 2069 · ICE 515 · EC 361 | On time 10:06 AM Karlsruhe Hbf | 9h15 | 7:21 PM Prague hlavní nádraží | 2 transfers | |
FlixTrain+ FlixBus | 1:23 PM Karlsruhe Hbf | 11h17 | 12:40 AM Prague, Central Train Station | 1 transfer | |
| Wednesday, February 4 | |||||
ICE 376 · ICE 1557 · RJ 383 | On time 6:59 AM Karlsruhe Hbf | 9h26 | 4:25 PM Prague hlavní nádraží | 2 transfers | |
ICE 267+ 359 | On time 7:05 AM Karlsruhe Hbf | 10h16 | 5:21 PM Prague hlavní nádraží | 1 transfer | |
ICE 267 · 89685 · 3565+ 357 | On time 7:05 AM Karlsruhe Hbf | 8h16 | 3:21 PM Prague hlavní nádraží | 3 transfers | |
ICE 267 · R 89685 · R 3565 · EC 357 | On time 7:05 AM Karlsruhe Hbf | 8h16 | 3:21 PM Prague hlavní nádraží | 3 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Karlsruhe to Prague by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 03
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Feb 16
How far in advance should I book train tickets from Karlsruhe to Prague?
Journey information
Overview: Train from Karlsruhe to Prague
Trains from Karlsruhe to Prague run on average 8 times per day, taking around 8h 55m. Cheap train tickets for this journey start at €28 but you can travel from only €26 by bus.
The earliest train runs at 00:19, the last at 23:50. The fastest train covers the 452 km distance in 8h 16m.
Distance 452 km |
Average train duration 8h 55m |
Cheapest ticket price €28 |
Trains per day 8 |
Fastest train 8h 16m |
First train 00:19 |
Last train 23:50 |
Train companies: Deutsche Bahn, Alex from Karlsruhe to Prague trainsDeutsche Bahn, Alex trains will get you between Karlsruhe and Prague from €26. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Alex
FAQs: Trains from Karlsruhe to Prague
Find answers to the most common questions about traveling from Karlsruhe to Prague by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Karlsruhe to Prague
- Monday: 06:30 - 21:00
- Tuesday: 06:30 - 21:00
- Wednesday: 06:30 - 21:00
- Thursday: 06:30 - 21:00
- Friday: 06:30 - 21:00
- Saturday: 08:00 - 19:00
- Sunday: 09:00 - 20:00
- Vinarte
- Am Tiergarten
- Panorama
- Alter Brauhof
- Hotel Barbarossa
- Hotel Avisa
- Am Tiergarten
- Aparthotel Aijana
- Monday: 08:00 13:30 - 12:30 18:00
- Tuesday: 08:00 13:30 - 12:30 18:00
- Wednesday: 08:00 13:30 - 12:30 18:00
- Thursday: 08:00 13:30 - 12:30 18:00
- Friday: 08:00 13:30 - 12:30 18:00
- Saturday: 09:00 - 13:00
- Hubraum
- Vogel Hausbräu Durlach
- Asia Gourmet
- Borsalino
- Hotel Große Linde
- Zum Erwin
- Der Blaue Reiter
- Beim Schupi
- Rosenstüble 2.0
- Saloniki
- Rote Taube
- Beim Schupi
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
- Restaurant Fantova Kavárna
- Sushi Time
- Outside the main entrance.
- Elevators, ramps.
- CZK 10
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
- Cost CZK 100
- Located in the main hall
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with several public parking options.
- Restaurant Kotleta
- Café Imperial
- Outside the main entrance.
- Ramps.
- CZK 10
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
Most popular train connections from Karlsruhe
More options for your journey from Karlsruhe to Prague
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