The cheapest and fastest trains from Karlsruhe to Prague
Cheapest price
€96
Average price
€174
Fastest journey
8 h 54 m
Average duration
9 h 15 m
Trains per day
10
Distance
452 km
The best way to find a cheap train ticket from Karlsruhe to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Prague will cost around €174 if you buy it on the day, but the cheapest tickets can be found for only €96.
It's difficult to get from Karlsruhe to Prague without transferring at least 2 times.
ICE 9571 · ICE 513+
359
RE 19673 · ICE 591 · RE 4068+
83927
ICE 267 · RE 26783 · Bus EV · RE 5287
IC 2067 · ICE 91+
359
ICE 267+
359
ICE 9571 · ICE 513+
359
ICE 267 · RE 26783 · Bus EV · RE 5287
IC 2067 · ICE 91+
359
ICE 374 · ICE 1557 · BUS 10175 · EC 175
ICE 372 · ICE 1559 · EC 10177 · EC 177Travel Information
Compare bus and train for Karlsruhe to Prague
Omio recommends booking the train as it is the most popular option from Karlsruhe to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €26. For those with little time consider booking a bus which can get you there in 7h 19m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €26, and a train costs an average of €28.
Distance: 452 km
Compare train with
Most popular Train | Bus |
|---|---|
€79 Average price | €43 Average price Cheapest |
9h 25m Average total duration 8h 55m Onboard + 30m Additional time* | 7h 49m Average total duration Fastest 7h 19m Onboard + 30m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.5 - 1.1kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Karlsruhe to Prague train times
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 9:07 PM Karlsruhe | 10h16 | 7:23 AM Prague | 0 transfersDirect | |
| Wednesday, November 5 | |||||
ICE 374 · ICE 1557 · BUS 10175 · EC 175 | On time 7:00 AM Karlsruhe Hbf | 9h23 | 4:23 PM Prague hlavní nádraží | 3 transfers | |
ICE 374 · ICE 1557 · EC 10175 · EC 175 | On time 7:00 AM Karlsruhe Hbf | 9h23 | 4:23 PM Prague hlavní nádraží | 3 transfers | |
ICE 267 · EC 359 | On time 7:05 AM Karlsruhe Hbf | 10h17 | 5:22 PM Prague hlavní nádraží | 1 transfer | |
ICE 267 · RE 26783 · Bus EV · RE 5287 | On time 7:05 AM Karlsruhe Hbf | 9h17 | 4:22 PM Prague hlavní nádraží | 4 transfers | |
ICE 267 · RE 4068 · R 83927 · Os 7551 | On time 7:05 AM Karlsruhe Hbf | 9h45 | 4:50 PM Praha-Smíchov | 4 transfers | |
ICE 267+ 359 | On time 7:05 AM Karlsruhe Hbf | 10h17 | 5:22 PM Prague hlavní nádraží | 1 transfer | |
RE 19673 · ICE 591 · RE 4068+ 83927 | On time 7:06 AM Karlsruhe Hbf | 9h44 | 4:50 PM Praha-Smíchov | 6 transfers | |
IC 2067 · ICE 91+ 359 | On time 8:05 AM Karlsruhe Hbf | 9h17 | 5:22 PM Prague hlavní nádraží | 2 transfers | |
ICE 9571 · ICE 513+ 359 | Delayed 8:45 AM 8:28 AMKarlsruhe Hbf | 8h54 | 5:22 PM Prague hlavní nádraží | 2 transfers | |
ICE 372 · ICE 1559 · EC 10177 · EC 177 | 9:00 AM Karlsruhe Hbf | 9h23 | 6:23 PM Prague hlavní nádraží | 3 transfers | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Karlsruhe to Prague by bus or train
Nov 05
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How far in advance should I book train tickets from Karlsruhe to Prague?
Journey information
Overview: Train from Karlsruhe to Prague
Distance 452 km |
Average train duration 8h 55m |
Cheapest ticket price €28 |
Trains per day 8 |
Fastest train 8h 16m |
First train 00:19 |
Last train 23:50 |
Train companies: Deutsche Bahn, Alex from Karlsruhe to Prague trainsDeutsche Bahn, Alex trains will get you between Karlsruhe and Prague from €26. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Deutsche Bahn
A Bordrestaurant (restaurant car) where you can sit and eat.
A Bordbistro (bistro bar) with snacks, hot meals, and drinks to-go.
At-seat service in 1st class: staff will take your order and serve food/drinks directly to your seat.
Regional trains (RE / RB / S-Bahn):
No onboard catering.
You’re welcome to bring your own food and drinks.
Not included by default.
You can add a seat reservation when booking (recommended for busy routes).
Costs around €4.90 per seat (or €5.90 if booked separately later).
First Class:
Yes, always included in the ticket price.
Allowed for free if they can fit in a transport box (max. size: hand luggage).
Must stay in the box for the entire journey.
Large dogs:
Require a separate (paid) ticket — typically half the price of a regular second-class ticket.
Must be leashed and wear a muzzle while on the train.
Cannot sit on seats.
Assistance dogs:
Travel free of charge.
Do not need a muzzle or leash if medically not required.
Allowed to accompany the passenger at all times.
Alex
FAQs: Trains from Karlsruhe to Prague

When departing from Karlsruhe, you have various train station options to start your trip from including Karlsruhe Hbf, Karlsruhe Bahnhofsvorplatz and Karlsruhe-Durlach station. When arriving in Prague, you can end your route in train stations like Prague hlavní nádraží, Prague-Holešovice and Praha-Kačerov.
Passengers board the train most frequently from Karlsruhe Hbf, which is located around 1.5 miles (2.4 km) away from the city centre, and they get off the train at Prague hlavní nádraží, located 1.8 miles (2.9 km) away from the city centre.
popular train stations
Popular train stations from Karlsruhe to Prague
- Monday: 06:30 - 21:00
- Tuesday: 06:30 - 21:00
- Wednesday: 06:30 - 21:00
- Thursday: 06:30 - 21:00
- Friday: 06:30 - 21:00
- Saturday: 08:00 - 19:00
- Sunday: 09:00 - 20:00
- Vinarte
- Am Tiergarten
- Panorama
- Alter Brauhof
- Hotel Barbarossa
- Hotel Avisa
- Am Tiergarten
- Aparthotel Aijana
- Beim Schupi
- Rosenstüble 2.0
- Saloniki
- Rote Taube
- Beim Schupi
- Monday: 08:00 13:30 - 12:30 18:00
- Tuesday: 08:00 13:30 - 12:30 18:00
- Wednesday: 08:00 13:30 - 12:30 18:00
- Thursday: 08:00 13:30 - 12:30 18:00
- Friday: 08:00 13:30 - 12:30 18:00
- Saturday: 09:00 - 13:00
- Hubraum
- Vogel Hausbräu Durlach
- Asia Gourmet
- Borsalino
- Hotel Große Linde
- Zum Erwin
- Der Blaue Reiter
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available 24/7 with access from Partyzánská street.
- Restaurant Na Kovárně
- Cross Club
- Outside the main entrance.
- Ramps, restrooms.
- CZK 10
- Mama Shelter Prague
- Plaza Alta Hotel
- Hotel Belvedere
- Located in the main hall
- Avis
- Budget
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-4 for trains to Germany, Austria, and regional destinations
- Hall 2: ticket office and waiting area
- Metro: Line C
- Tram: Lines 6, 12, 17
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available nearby with several public parking options.
- Restaurant Kotleta
- Café Imperial
- Outside the main entrance.
- Ramps.
- CZK 10
- Hotel Kings Court
- Grand Hotel Bohemia
- Hotel Paris Prague
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-5 for regional and suburban trains
- Metro: Line B
- Tram: Lines 3, 5, 14, 24
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available near the station, with access from Boženy Němcové street.
- Ansámbl
- Bad Flash Bar
- Café Sladkovský
- Outside the main entrance.
- Ramps, restrooms.
- CZK 10
- Hotel Mars
- Hotel Slavia
- Hotel Nabucco
- Located in the main hall
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-4 for regional and suburban trains
- Tram: Line 6, Line 7, Line 24
- Bus: Several lines available
- Train: Connections to Praha hlavní nádraží
- 5:00 AM - 12:00 AM Monday - Sunday
- Free
- Parking is available near the station, with access from the main road.
- Restaurant U Kačerova
- Pizza Coloseum Budějovická
- Outside the main entrance.
- Elevators, ramps.
- CZK 10
- Hotel ILF
- Hotel Oya
- Hotel Pankrác
- Located in the main hall
- Free
- Hall 1: main entrance, platform access for Metro Line C
- Hall 2: bus connections
- Metro: Line C
- Bus: Several lines available
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- The car park is open 7 days a week, 24 hours a day. Access via Wilsonova Street.
- Restaurant Fantova Kavárna
- Sushi Time
- Outside the main entrance.
- Elevators, ramps.
- CZK 10
- Hotel Esplanade Prague
- Falkensteiner Hotel Maria Prag
- Hotel City Central
- Cost CZK 100
- Located in the main hall
- Located in the main hall
- Avis
- Europcar
- Hertz
- Located in the main hall
- Free
- Hall 1: main entrance, platform 1-7 for trains to Germany, Austria, Slovakia, and regional destinations
- Hall 2: Metro connections
- Metro: Line C
- Tram: Lines 5, 9, 26
- Bus: Several lines available
Most popular train connections from Karlsruhe
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