The cheapest and fastest buses from Karlsruhe to Prague
Cheapest price
€51
Average price
€75
Fastest journey
8 h 5 m
Average duration
8 h 34 m
Buses per day
26
Distance
452 km
The best way to find a cheap bus ticket from Karlsruhe to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Prague will cost around €75 if you buy it on the day, but the cheapest tickets can be found for only €51.
Of the 26 buses that leave Karlsruhe for Prague on Fri, Aug 14, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Aug 14 the direct buses cover the 452 km distance in an average of 8 h 34 m but if you time it right, some buses will get you there in just 8 h 5 m .
On Fri, Aug 14 the slowest buses will take 8 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus1:20 PM8h30Karlsruhe Hbf9:50 PMPraha, ÚAN Florenc€511One-way0 transfers
FlixBus6:25 AM9h45Karlsruhe Hbf4:10 PMPraha, Černý Most€641One-way0 transfers
FlixBus6:25 AM9h00Karlsruhe Hbf3:25 PMPraha, ÚAN Florenc€641One-way0 transfers
FlixBus · FlixBus1:55 AM9h25Karlsruhe Hbf11:20 AMPrague, Central Train Station€641One-way1 transfer
FlixBus · FlixBus1:55 AM9h35Karlsruhe Hbf11:30 AMPraha, ÚAN Florenc€641One-way1 transfer
FlixBus11:25 PM8h05Karlsruhe Hbf7:30 AMPraha, M. Horákové (Hradčanská)€681One-way0 transfers
FlixBus11:25 PM8h25Karlsruhe Hbf7:50 AMPraha, ÚAN Florenc€681One-way0 transfers
FlixBus1:20 PM8h30Karlsruhe Hbf9:50 PMPraha, ÚAN Florenc€511One-way0 transfers
FlixBus · FlixBus12:15 PM8h55Karlsruhe Hbf9:10 PMPraha, Na Knížecí€651One-way1 transfer
FlixBus8:35 AM8h55Karlsruhe Hbf5:30 PMPrague, Central Train Station€751One-way0 transfers
Travel Information
Compare train and bus for Karlsruhe to Prague
Omio recommends booking the train as it is the most popular option from Karlsruhe to Prague among Omio's users. If you are prioritising price take the bus with prices starting from €25. For those with little time consider booking a bus which can get you there in 7h 29m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €25, and a train costs an average of €28.
Distance: 452 km
Compare bus with
| Bus | Most popular Train |
|---|---|
€40 Average price Cheapest | €64 Average price |
7h 59m Average total duration Fastest 7h 29m Onboard + 30m Additional time* | 9h 35m Average total duration 9h 5m Onboard + 30m Additional time* |
0.5 - 1.1kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Karlsruhe to Prague bus times
The table below shows live departures for Karlsruhe to Prague buses for today, Thursday, August 13. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 8:35 AM Karlsruhe Hbf | 9h10 | 5:45 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus | 8:35 AM Karlsruhe Hbf | 8h55 | 5:30 PM Prague, Central Train Station | 0 transfersDirect | |
FlixBus · FlixBus | 10:15 AM Karlsruhe Hbf | 10h05 | 8:20 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 12:15 PM Karlsruhe Hbf | 8h55 | 9:10 PM Praha, Na Knížecí | 1 transfer | |
FlixBus | 12:15 PM Karlsruhe Hbf | 10h25 | 10:40 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 12:15 PM Karlsruhe Hbf | 11h40 | 11:55 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:20 PM Karlsruhe Hbf | 9h35 | 10:55 PM Praha, Na Knížecí | 1 transfer | |
FlixBus | 1:20 PM Karlsruhe Hbf | 8h30 | 9:50 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 1:20 PM Karlsruhe Hbf | 11h25 | 12:45 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 4:20 PM Karlsruhe Hbf | 10h55 | 3:15 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 8:20 PM Karlsruhe Hbf | 10h35 | 6:55 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 11:25 PM Karlsruhe Hbf | 9h30 | 8:55 AM Praha, Na Knížecí | 1 transfer | |
FlixBus | 11:25 PM Karlsruhe Hbf | 8h25 | 7:50 AM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 11:25 PM Karlsruhe Hbf | 11h10 | 10:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus | 11:25 PM Karlsruhe Hbf | 8h05 | 7:30 AM Praha, M. Horákové (Hradčanská) | 0 transfersDirect | |
FlixBus · FlixBus | 11:25 PM Karlsruhe Hbf | 9h05 | 8:30 AM Praha, Zličín | 1 transfer | |
| Friday, August 14 | |||||
FlixBus · FlixBus | 12:05 AM Karlsruhe Hbf | 10h30 | 10:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 12:05 AM Karlsruhe Hbf | 10h40 | 10:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 1:55 AM Karlsruhe Hbf | 9h25 | 11:20 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 1:55 AM Karlsruhe Hbf | 9h35 | 11:30 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 2:15 AM Karlsruhe Hbf | 10h10 | 12:25 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 2:15 AM Karlsruhe Hbf | 9h55 | 12:10 PM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 3:05 AM Karlsruhe Hbf | 11h40 | 2:45 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 4:55 AM Karlsruhe Hbf | 9h40 | 2:35 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 6:25 AM Karlsruhe Hbf | 9h45 | 4:10 PM Praha, Černý Most | 0 transfersDirect | |
FlixBus | 6:25 AM Karlsruhe Hbf | 9h00 | 3:25 PM Praha, ÚAN Florenc | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Karlsruhe to Prague by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Aug 14
Aug 15
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Aug 18
Aug 19
Aug 20
Aug 21
Aug 22
Aug 23
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Aug 26
Aug 27
Aug 28
Aug 29
Aug 30
Aug 31
Sep 01
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Sep 03
Why should you book Karlsruhe to Prague buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Karlsruhe to Prague.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Karlsruhe to Prague.
Journey information
Overview: Bus from Karlsruhe to Prague
Buses from Karlsruhe to Prague run on average 24 times per day, taking around 7h 29m. Cheap bus tickets for this journey start at €25 if you book in advance.
There are 8 buses per day. The earliest bus runs at 00:05, the last at 23:50. The fastest bus covers the 452 km distance in 8h 5m.
Distance 452 km |
Average bus duration 7h 29m |
Cheapest ticket price €25 |
Buses per day 24 |
Direct buses 8 |
Fastest bus 8h 5m |
First bus 12:05 AM |
Last bus 11:50 PM |
Cheapest Month Mar |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Wed |
Best time to book 63 days |
Bus providers: FlixBus, BlaBlaCar from Karlsruhe to PragueYou can travel by bus between Karlsruhe to Prague with FlixBus, BlaBlaCar for as low as €25. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
FAQs: Bus from Karlsruhe to Prague
Find answers to the most common questions about traveling from Karlsruhe to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Karlsruhe to Prague
Most Karlsruhe to Prague buses use the Karlsruhe Hbf to Praha, Hlavní Nádraží station pair, with some services arriving at Praha, ÚAN Florenc. Use this guide to compare Karlsruhe and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to Karlsruhe Hbf from Karlsruhe city centre
Getting to Karlsruhe, Hinterm Hauptbahnhof (Südeingang) from Karlsruhe city centre
Karlsruhe, Hinterm Hauptbahnhof (Südeingang) is 1 km from Karlsruhe city centre. Public transport options include:
Karlsruhe, Hinterm Hauptbahnhof (Südeingang) bus station facilities and services
Karlsruhe, Hinterm Hauptbahnhof (Südeingang) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang). ATMs are available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang).
Tickets and information
Ticket office support is available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang).
Parking, taxis and toilets
Available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang): The station is accessible for passengers with reduced mobility.
Which Prague station do buses from Karlsruhe arrive at?
Getting to Praha, ÚAN Florenc from Prague city centre
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc bus station facilities and services
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Tickets and information
Ticket office support is available at Praha, ÚAN Florenc.
Parking, taxis and toilets
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Getting to Praha, Hlavní Nádraží from Prague city centre
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží bus station facilities and services
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Tickets and information
Ticket office support is available at Praha, Hlavní Nádraží.
Parking, taxis and toilets
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Getting to Praha, Na Knížecí from Prague city centre
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí bus station facilities and services
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food and drink
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the entrance.
Parking, taxis and toilets
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
More options for your journey from Karlsruhe to Prague
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