The cheapest and fastest buses from Karlsruhe to Prague
- Cheapest price on Nov 13
- €42
- Average ticket price on Nov 13
- €59
- Fastest journey on Nov 13
- 8 h 5 m
- Average journey duration on Nov 13
- 8 h 34 m
- Buses on Nov 13
- 20
- Distance
- 452 km
The best way to find a cheap bus ticket from Karlsruhe to Prague is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Karlsruhe to Prague will cost around €59 if you buy it on the day, but the cheapest tickets can be found for only €42.
On Fri, Nov 13, we found 20 buses from Karlsruhe to Prague, including 8 direct services.
On Fri, Nov 13 the direct buses cover the 452 km distance in an average of 8 h 34 m but if you time it right, some buses will get you there in just 8 h 5 m .
On Fri, Nov 13 the slowest buses will take 8 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus1:20 PM 8h30 Karlsruhe Hbf 9:50 PM Praha, ÚAN Florenc €42 1 One-way 0 transfers
FlixBus12:15 PM 10h25 Karlsruhe Hbf 10:40 PM Praha, ÚAN Florenc €46 1 One-way 0 transfers
FlixBus · FlixBus8:20 PM 10h35 Karlsruhe Hbf 6:55 AM Praha, ÚAN Florenc €54 1 One-way 1 transfer
FlixBus · FlixBus4:20 PM 10h55 Karlsruhe Hbf 3:15 AM Prague, Central Train Station €54 1 One-way 1 transfer
FlixBus · FlixBus1:20 PM 9h35 Karlsruhe Hbf 10:55 PM Praha, Na Knížecí €56 1 One-way 1 transfer
FlixBus11:25 PM 8h05 Karlsruhe Hbf 7:30 AM Praha, M. Horákové (Hradčanská) €64 1 One-way 0 transfers
FlixBus11:25 PM 8h25 Karlsruhe Hbf 7:50 AM Praha, ÚAN Florenc €64 1 One-way 0 transfers
FlixBus1:20 PM 8h30 Karlsruhe Hbf 9:50 PM Praha, ÚAN Florenc €42 1 One-way 0 transfers
FlixBus · FlixBus12:15 PM 8h55 Karlsruhe Hbf 9:10 PM Praha, Na Knížecí €58 1 One-way 1 transfer
FlixBus8:35 AM 8h55 Karlsruhe Hbf 5:30 PM Prague, Central Train Station €62 1 One-way 0 transfers
Journey information
Overview: Bus from Karlsruhe to Prague
Buses from Karlsruhe to Prague run on average 24 times per day, taking around 8h 46m. Cheap bus tickets for this journey start at €24 but you can travel from only €7 by train.
There are 8 buses per day. The earliest bus runs at 00:05, the last at 23:50. The fastest bus covers the 452 km distance in 7h 10m.
Distance 452 km |
Average bus duration 8h 46m |
Cheapest ticket price €24 |
Buses per day 24 |
Direct buses 8 |
Fastest bus 7h 10m |
First bus 12:05 AM |
Last bus 11:50 PM |
Cheapest Month Mar |
Cheapest Day Mon |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sat |
Best time to book 42 days |
Frequently asked questions about your Karlsruhe to Prague trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Karlsruhe to Prague.
Live departures
Karlsruhe to Prague bus times
The table below shows live departures for Karlsruhe to Prague buses for today, Thursday, November 12. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 2:15 AM Karlsruhe Hbf | 10h10 | 12:25 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 2:15 AM Karlsruhe Hbf | 9h55 | 12:10 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 8:35 AM Karlsruhe Hbf | 8h55 | 5:30 PM Prague, Central Train Station | 0 transfersDirect | |
FlixBus | 8:35 AM Karlsruhe Hbf | 9h10 | 5:45 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 10:15 AM Karlsruhe Hbf | 10h05 | 8:20 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 12:15 PM Karlsruhe Hbf | 11h40 | 11:55 PM Prague, Central Train Station | 1 transfer | |
FlixBus | 12:15 PM Karlsruhe Hbf | 10h25 | 10:40 PM Praha, ÚAN Florenc | 0 transfersDirect | |
FlixBus · FlixBus | 12:15 PM Karlsruhe Hbf | 8h55 | 9:10 PM Praha, Na Knížecí | 1 transfer | |
FlixBus+ FlixTrain | 2:23 PM Karlsruhe Hbf | 8h47 | 11:10 PM Praha, ÚAN Florenc | 1 transfer | |
FlixBus+ FlixTrain | 2:23 PM Karlsruhe Hbf | 8h32 | 10:55 PM Praha, Na Knížecí | 1 transfer | |
FlixBus · FlixBus | 4:20 PM Karlsruhe Hbf | 10h55 | 3:15 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 8:20 PM Karlsruhe Hbf | 10h35 | 6:55 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 9:50 PM Karlsruhe Hbf | 12h20 | 10:10 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 11:20 PM Karlsruhe Hbf | 11h15 | 10:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 11:20 PM Karlsruhe Hbf | 11h25 | 10:45 AM Praha, ÚAN Florenc | 1 transfer | |
FlixBus · FlixBus | 12:05 AM Karlsruhe Hbf | 10h30 | 10:35 AM Prague, Central Train Station | 1 transfer | |
FlixBus · FlixBus | 12:05 AM Karlsruhe Hbf | 10h40 | 10:45 AM Praha, ÚAN Florenc | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Karlsruhe to Prague buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of AMI-Tour, Infobus or BlaBlaCar Bus to find the best option for your trip from Karlsruhe to Prague.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Karlsruhe to Prague.
Why book with Omio over Wanderu, Trainline or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of AMI-Tour, Infobus or BlaBlaCar Bus to find the best option for your trip from Karlsruhe to Prague.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Karlsruhe to Prague.
Bus providers: FlixBus, AMI-Tour, Infobus, BlaBlaCar Bus from Karlsruhe to PragueYou can travel by bus between Karlsruhe to Prague with FlixBus, AMI-Tour, Infobus, BlaBlaCar Bus for as low as €7. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
BlaBlaCar Bus
AMI-Tour
Companies, tickets, and onboard amenities between Karlsruhe and Prague
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- 10€ per additional bag.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
FAQs: Bus from Karlsruhe to Prague
Find answers to the most common questions about traveling from Karlsruhe to Prague by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Prague, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Karlsruhe to Prague
Most Karlsruhe to Prague buses use the Karlsruhe Hbf to Praha, ÚAN Florenc station pair, with some services arriving at Praha, Hlavní Nádraží. Use this guide to compare Karlsruhe and Prague bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to Karlsruhe Hbf from Karlsruhe city centre
Getting to Karlsruhe, Hinterm Hauptbahnhof (Südeingang) from Karlsruhe city centre
Karlsruhe, Hinterm Hauptbahnhof (Südeingang) is 1 km from Karlsruhe city centre. Public transport options include:
Karlsruhe, Hinterm Hauptbahnhof (Südeingang) bus station facilities and services
Karlsruhe, Hinterm Hauptbahnhof (Südeingang) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang). ATMs are available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang).
Tickets and information
Ticket office support is available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang).
Parking, taxis and toilets
Available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Karlsruhe, Hinterm Hauptbahnhof (Südeingang): The station is accessible for passengers with reduced mobility.
Which Prague station do buses from Karlsruhe arrive at?
Getting to Praha, ÚAN Florenc from Prague city centre
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc bus station facilities and services
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Tickets and information
Ticket office support is available at Praha, ÚAN Florenc.
Parking, taxis and toilets
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Getting to Praha, Hlavní Nádraží from Prague city centre
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží bus station facilities and services
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Tickets and information
Ticket office support is available at Praha, Hlavní Nádraží.
Parking, taxis and toilets
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Getting to Praha, Na Knížecí from Prague city centre
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí bus station facilities and services
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food and drink
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the entrance.
Parking, taxis and toilets
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
More options for your journey from Karlsruhe to Prague
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