The cheapest and fastest trains from Mestre to Rome
Cheapest price
€53
Average price
€91
Fastest journey
4 h 7 m
Average duration
4 h 18 m
Trains per day
28
Distance
400 km
The best way to find a cheap train ticket from Mestre to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Mestre to Rome will cost around €91 if you buy it on the day, but the cheapest tickets can be found for only €53.
It's difficult to get from Mestre to Rome without transferring at least once.
Regionale 16831+
InterCityNotte 7709:26 PM9h09Venezia Mestre Ospedale6:35 AMRome Termini€531One-way1 transfer
Regionale 16791+
Intercity 5942:58 PM7h22Venezia Mestre Ospedale10:20 PMRome Termini€591One-way1 transfer
Regionale 16775+
Intercity 58412:26 PM8h19Venezia Mestre Ospedale8:45 PMRome Termini€591One-way1 transfer
Regionale 16037 · Regionale Veloce 3961+
Intercity 5835:20 AM8h07Venezia Mestre Ospedale1:27 PMRome Tiburtina€641One-way2 transfers
Regionale 16781 · Regionale Veloce 3977+
Intercity 5971:26 PM7h41Venezia Mestre Ospedale9:07 PMRome Tiburtina€641One-way2 transfers
Regionale 16870+
FRECCIAROSSA 94667:58 AM4h07Venezia Mestre Ospedale12:05 PMRome Termini€1031One-way1 transfer
Regionale 16037+
FRECCIAROSSA 94015:20 AM4h13Venezia Mestre Ospedale9:33 AMRome Termini€1031One-way1 transfer
Regionale 16836 · Regionale Veloce 3637+
FRECCIAROSSA 94057:02 AM4h20Venezia Mestre Ospedale11:22 AMRome Termini€1031One-way2 transfers
Regionale 16757+
FRECCIAROSSA 94056:58 AM4h24Venezia Mestre Ospedale11:22 AMRome Termini€1031One-way1 transfer
Regionale 16232+
FRECCIAROSSA 841911:58 AM4h26Venezia Mestre Ospedale4:24 PMRome Termini€1031One-way1 transfer
Travel Information
Compare train, bus, and flight for Mestre to Rome
Omio recommends booking the train as it is the most popular option from Mestre to Rome among Omio's users. If you are prioritising price take the train with prices starting from €22. For those with little time consider booking a flight which can get you there in 1h 9m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a train costs an average of €22, and a flight costs an average of €40.
Distance: 400 km
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€48 Average price Cheapest | €54 Average price | €169 Average price |
6h 38m Average total duration 6h 8m Onboard + 30m Additional time* | 7h 20m Average total duration 6h 50m Onboard + 30m Additional time* | 4h 9m Average total duration Fastest 1h 9m Onboard + 3h 0m Additional time* |
0.1 - 0.4kg CO2 emissions Lowest | 0.4 - 1.0kg CO2 emissions | 1.2 - 2.4kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Mestre to Rome train times
The table below shows live departures for Mestre to Rome trains for today, Tuesday, April 28. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Regionale 16831+ InterCityNotte 770 | 9:26 PM Venezia Mestre Ospedale | 9h09 | 6:35 AM Rome Termini | 1 transfer | |
| Wednesday, April 29 | |||||
Regionale 16037 · Regionale Veloce 3961+ Intercity 583 | 5:20 AM Venezia Mestre Ospedale | 8h07 | 1:27 PM Rome Tiburtina | 2 transfers | |
Regionale 16037+ FRECCIAROSSA 9401 | 5:20 AM Venezia Mestre Ospedale | 4h13 | 9:33 AM Rome Termini | 1 transfer | |
Regionale 16845+ FRECCIAROSSA 9403 | 5:58 AM Venezia Mestre Ospedale | 4h27 | 10:25 AM Rome Termini | 1 transfer | |
Regionale 16121+ FRECCIAROSSA 8801 · FRECCIAROSSA 9611 | 6:26 AM Venezia Mestre Ospedale | 4h44 | 11:10 AM Rome Termini | 2 transfers | |
Regionale 16757+ FRECCIAROSSA 9405 | 6:58 AM Venezia Mestre Ospedale | 4h24 | 11:22 AM Rome Termini | 1 transfer | |
Regionale 16836 · Regionale Veloce 3637+ FRECCIAROSSA 9405 | 7:02 AM Venezia Mestre Ospedale | 4h20 | 11:22 AM Rome Termini | 2 transfers | |
Regionale 16870+ FRECCIAROSSA 9466 | 7:58 AM Venezia Mestre Ospedale | 4h07 | 12:05 PM Rome Termini | 1 transfer | |
Regionale 16811 · Regionale Veloce 3967+ FRECCIAROSSA 9619 | 8:36 AM Venezia Mestre Ospedale | 4h34 | 1:10 PM Rome Termini | 2 transfers | |
Regionale 16874+ FRECCIAROSSA 9411 | 8:58 AM Venezia Mestre Ospedale | 4h32 | 1:30 PM Rome Termini | 1 transfer | |
Regionale 16726 · Regionale Veloce 3997+ FRECCIAROSSA 9623 | 9:28 AM Venezia Mestre Ospedale | 4h42 | 2:10 PM Rome Termini | 2 transfers | |
Regionale 16680+ FRECCIAROSSA 9413 | 9:58 AM Venezia Mestre Ospedale | 4h27 | 2:25 PM Rome Termini | 1 transfer | |
Regionale 16232+ FRECCIAROSSA 8419 | 11:58 AM Venezia Mestre Ospedale | 4h26 | 4:24 PM Rome Termini | 1 transfer | |
Regionale 16775 · Regionale Veloce 3975+ FRECCIAROSSA 9637 | 12:26 PM Venezia Mestre Ospedale | 4h44 | 5:10 PM Rome Termini | 2 transfers | |
Regionale 16775+ Intercity 584 | 12:26 PM Venezia Mestre Ospedale | 8h19 | 8:45 PM Rome Termini | 1 transfer | |
Regionale 16779+ FRECCIAROSSA 9421 | 12:58 PM Venezia Mestre Ospedale | 4h26 | 5:24 PM Rome Termini | 1 transfer | |
Regionale 16781 · Regionale Veloce 3977+ Intercity 597 | 1:26 PM Venezia Mestre Ospedale | 7h41 | 9:07 PM Rome Tiburtina | 2 transfers | |
Regionale 16781 · Regionale Veloce 3977+ FRECCIAROSSA 9641 | 1:26 PM Venezia Mestre Ospedale | 4h49 | 6:15 PM Rome Termini | 2 transfers | |
Regionale 16787 · Regionale Veloce 3979+ FRECCIAROSSA 9645 | 2:28 PM Venezia Mestre Ospedale | 4h47 | 7:15 PM Rome Termini | 2 transfers | |
Regionale 16791+ Intercity 594 | 2:58 PM Venezia Mestre Ospedale | 7h22 | 10:20 PM Rome Termini | 1 transfer | |
Regionale 16791+ FRECCIAROSSA 9427 | 2:58 PM Venezia Mestre Ospedale | 4h27 | 7:25 PM Rome Termini | 1 transfer | |
Regionale 16793 · Regionale Veloce 3981+ FRECCIAROSSA 9649 | 3:26 PM Venezia Mestre Ospedale | 4h50 | 8:16 PM Rome Termini | 2 transfers | |
Regionale 16768+ FRECCIAROSSA 9431 | 3:58 PM Venezia Mestre Ospedale | 4h27 | 8:25 PM Rome Termini | 1 transfer | |
Regionale 16801 · Regionale Veloce 3983+ FRECCIAROSSA 9653 | 4:28 PM Venezia Mestre Ospedale | 4h42 | 9:10 PM Rome Termini | 2 transfers | |
Regionale 16805+ FRECCIAROSSA 9433 | 4:58 PM Venezia Mestre Ospedale | 4h32 | 9:30 PM Rome Termini | 1 transfer | |
Regionale 16809 · Regionale Veloce 3985+ FRECCIAROSSA 9661 | 5:26 PM Venezia Mestre Ospedale | 4h44 | 10:10 PM Rome Termini | 2 transfers | |
Regionale 16852+ FRECCIAROSSA 9435 | 5:58 PM Venezia Mestre Ospedale | 4h27 | 10:25 PM Rome Termini | 1 transfer | |
Regionale 16258+ FRECCIAROSSA 9437 | 6:58 PM Venezia Mestre Ospedale | 4h32 | 11:30 PM Rome Termini | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Mestre to Rome by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 29
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Why should you book Mestre to Rome trains with Omio?
Why book with Omio vs Frecciarossa?
- Compare with other providers: On Omio, you can not only buy tickets for Frecciarossa, but also compare tickets for the likes of Italo, Intercity Notte, Intercity or Regionale to find the best option for your trip from Mestre to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Frecciarossa with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Mestre to Rome.
Why book with Omio over Raileurope?
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Mestre to Rome.
How far in advance should I book train tickets from Mestre to Rome?
Journey information
Overview: Train from Mestre to Rome
Trains from Mestre to Rome run on average 25 times per day, taking around 6h 8m. Cheap train tickets for this journey start at €22 but you can travel from only €17 by bus.
There are 2 trains per day. The earliest train runs at 00:15, the last at 23:49. The fastest train covers the 400 km distance in 3h 37m.
Distance 400 km |
Average train duration 6h 8m |
Cheapest ticket price €22 |
Trains per day 25 |
Direct trains 2 |
Fastest train 3h 37m |
First train 12:15 AM |
Last train 11:49 PM |
Cheapest Month Aug |
Cheapest Day Sun |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Tue |
Best time to book 77 days |
Train companies: Frecciarossa, Italo, Intercity Notte, Intercity, Regionale from Mestre to Rome trainsFrecciarossa, Italo, Intercity Notte, Intercity, Regionale trains will get you between Mestre and Rome from €17. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Frecciarossa
Italo
Intercity Notte
Intercity
Regionale
FAQs: Trains from Mestre to Rome
Find answers to the most common questions about traveling from Mestre to Rome by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Mestre to Rome
- 6:00 AM - 10:00 PM Monday - Sunday
- Parking is available near the station, open 24/7.
- Outside the main entrance.
- €1
- Hotel Villa Sara
- Hotel Altieri
- Hotel Ducale
- Located near the main entrance
- The station has a simple layout with two platforms and a small waiting area.
- Bus: Several ACTV lines available
- Tram: Line T1
- Mon - Sun: 06:30 - 22:00
- Free WiFi in the station.
- Provided by KiPoint and located on Platform 24. Open every day from 06:00 to 23:00.
- Acafe
- Moka Café
- Roadhouse Grill
- McDonald's
- Gusto
- Chef Express
- Coop Minimarket
- Mercato Centrale
- The Sala Blu, Trenitalia's office of assistance for disabled travelers, is located next to Platform 1.
- Archi di Roma Guest House
- Gemma di Roma
- The Liberty Boutique Hotel
- Mon - Sun: 06:30 - 22:00
- Located near Platform 24.
- Metro lines: A (red), B (blue)
- Bus lines: 5, H, 38, 40 Express, 50 Express, 64, 66, 70, 75, 82, 90 Express, 92, 105, 150F, 223, 310, 590, 714, 910, C2, C3
- Tram lines: 5, 14
- Train lines: Italo, FR, FA, FB, IC, ICN, EN, CNL, R, Leonardo Express
- Mon - Sun: 06:35 - 20:20
- Free, limited Wi-Fi available in the station for 15 minutes.
- Luggage lockers are located in the station lobby.
- Rock n’ Coffee Roma
- Arabian Kebab
- Ingredienti
- McDonald’s
- Numb's Bakery Café
- Accessible facilities include elevators and escalators.
- B&B Rome Tiburtina
- B&B Alba Domus Roma
- Hotel delle Province
- Mon - Sun: 06:35 - 20:20
- Located inside the main terminal.
- Metro lines: LB
- Bus lines: 62, 71, 111, 111F, 120F, 135, 163, 168, 211, 309, 409, n409, n041, C2, C3, Airport Shuttle
- Train lines: FR, FA, IC, REG, FL1, FL2, FL3
- 6:00 AM - 10:00 PM Monday - Sunday
- Free
- Parking is available near the station with both short-term and long-term options.
- Ramen Bar Akira
- Eataly Roma
- Outside the main entrance.
- Elevators, ramps, restrooms.
- €1
- Hotel Abitart
- Hotel San Anselmo
- Hotel Villa San Pio
- Located in the main hall
- Avis
- Europcar
- Located in the main hall
- Free
- Hall 1: main entrance, platforms 1-5 for regional and intercity trains
- Hall 2: platforms 6-11 for metropolitan services
- Metro: Line B
- Bus: Several lines available
- Tram: Line 3
Most popular train connections from Mestre
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