Milan Centrale to Siena train with Italo

Sun, Feb 22
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Italo
Frecciarossa
Intercity
Regionale
Intercity Notte
1,000+ travel companies
Italo
Frecciarossa
Intercity
Regionale
Intercity Notte
1,000+ travel companies
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The cheapest and fastest trains from Milan Centrale to Siena

Showing times and prices for Feb 24

Cheapest price

€36

Average price

€76

Fastest journey

4 h 2 m

Average duration

4 h 3 m

Trains per day

46

Distance

294 km

Cheap tickets

The best way to find a cheap train ticket from Milan Centrale to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Milan Centrale to Siena will cost around €76 if you buy it on the day, but the cheapest tickets can be found for only €36.

Fast trains

It's difficult to get from Milan Centrale to Siena without transferring at least 2 times.

RegionaleRegionale 2293 · Regionale 18413 · Regionale 18217
06:50AM8h47
Milan Centrale
03:37PMSiena station
361One-way
2 transfers
IntercityIntercity 657+RegionaleRegionale 18413 · Regionale 18217
08:05AM7h32
Milan Centrale
03:37PMSiena station
531One-way
2 transfers
IntercityIntercity 665+RegionaleRegionale 18399 · Regionale 18223
12:10PM6h30
Milan Centrale
06:40PMSiena station
531One-way
2 transfers
IntercityIntercity 583+RegionaleRegionale 18209
06:05AM6h33
Milan Centrale
12:38PMSiena station
531One-way
1 transfer
IntercityIntercity 597+RegionaleETRUSCHI LINE 18307 · Regionale 19051
01:48PM5h28
Milan Centrale
07:16PMSiena station
531One-way
2 transfers

Travel Information

Compare bus and train for Milan Centrale to Siena

Omio recommends booking the train as it is the most popular option from Milan Centrale to Siena among Omio's users. If you are prioritising price take the bus with prices starting from €8. For those with little time consider booking a train which can get you there in 4h 54m. The ticket price range depends on the travel mode: a bus costs an average of €8, and a train costs an average of €26.

Distance: 294 km

Compare train with

Most popular
Train
Bus

€34

Average price

€15

Average price

Cheapest

5h 24m

Average total duration

Fastest

4h 54m

Onboard

+

30m

Additional time*

5h 37m

Average total duration

5h 7m

Onboard

+

30m

Additional time*

Italo

Most popular train company

FlixBus

Most popular bus company

Direct Options

Direct Options

Live departures

Milan Centrale to Siena train times

The table below shows live departures for Milan Centrale to Siena trains for today, Monday, February 23. You can also manually refresh the results below to see updated train journeys.

Last updated at 11:30 AM
ProviderDepartsDurationArrivesTransfers
Tickets
trenitaliaint4:40 PM Milan Centrale
5h36
10:16 PM Siena0 transfersDirect
Tuesday, February 24
frecciarossaFRECCIAROSSA 9505+trenitaliaregTuscany Line 4013 · Regionale 190354:10 AM Milan Centrale
4h07
8:17 AM Siena station2 transfers
frecciarossaFRECCIAROSSA 9505+trenitaliaregRegionale 182034:10 AM Milan Centrale
4h28
8:38 AM Siena station1 transfer
frecciarossaFRECCIAROSSA 1000 9601 · FRECCIAROSSA 9401+trenitaliaregRegionale 182034:20 AM Milan Centrale
4h18
8:38 AM Siena station2 transfers
trenitaliaintIntercity 583+trenitaliaregRegionale 182095:05 AM Milan Centrale
6h33
11:38 AM Siena station1 transfer
frecciarossaFRECCIAROSSA 1000 9511+trenitaliaregRegionale Veloce 4017 · Regionale 190375:10 AM Milan Centrale
4h06
9:16 AM Siena station2 transfers
trenitaliaintIntercity 651+trenitaliaregRegionale 18409 · Regionale 182095:10 AM Milan Centrale
6h28
11:38 AM Siena station2 transfers
frecciarossaFRECCIAROSSA 1000 9511+trenitaliaregRegionale 182055:10 AM Milan Centrale
4h30
9:40 AM Siena station1 transfer
trenitaliaregRegionale Veloce 3013+trenitaliaintIntercity 505+trenitaliaregRegionale 191225:25 AM Milan Centrale
9h05
2:30 PM Siena station2 transfers
trenitaliaregRegionale 2293 · Regionale 18413 · Regionale 182175:50 AM Milan Centrale
8h47
2:37 PM Siena station2 transfers
frecciarossaFRECCIAROSSA 9515+trenitaliaregRegionale 182076:10 AM Milan Centrale
4h30
10:40 AM Siena station1 transfer
trenitaliaintIntercity 657+trenitaliaregRegionale 18413 · Regionale 182177:05 AM Milan Centrale
7h32
2:37 PM Siena station2 transfers
frecciarossaFRECCIAROSSA 9519+trenitaliaregRegionale 182097:10 AM Milan Centrale
4h28
11:38 AM Siena station1 transfer
frecciarossaFRECCIAROSSA 9583+trenitaliaregETRUSCHI LINE 4027 · Regionale 190398:10 AM Milan Centrale
4h05
12:15 PM Siena station2 transfers
frecciarossaFRECCIAROSSA 9583+trenitaliaregRegionale 182118:10 AM Milan Centrale
4h30
12:40 PM Siena station1 transfer
trenitaliaintIntercity 659 · Intercity 511+trenitaliaregRegionale 191268:10 AM Milan Centrale
9h03
5:13 PM Siena station2 transfers
frecciarossaFRECCIAROSSA 9527+trenitaliaregRegionale 182159:10 AM Milan Centrale
4h30
1:40 PM Siena station1 transfer
frecciarossaFRECCIAROSSA 9527+trenitaliaregTUSCANY LINE 4029 · Regionale 190419:10 AM Milan Centrale
4h06
1:16 PM Siena station2 transfers
frecciarossaFRECCIAROSSA 9587+trenitaliaregTuscany Line 4033 · Regionale 1904310:10 AM Milan Centrale
4h07
2:17 PM Siena station2 transfers
frecciarossaFRECCIAROSSA 9587+trenitaliaregRegionale 1821710:10 AM Milan Centrale
4h27
2:37 PM Siena station1 transfer
frecciarossaFRECCIAROSSA 8807 · FRECCIAROSSA 1000 9415+trenitaliaregRegionale 1821710:35 AM Milan Centrale
4h02
2:37 PM Siena station2 transfers
trenitaliaintIntercity 665+trenitaliaregRegionale 18399 · Regionale 1822311:10 AM Milan Centrale
6h30
5:40 PM Siena station2 transfers
frecciarossaFRECCIAROSSA 9535+trenitaliaregRegionale Veloce 4035 · Regionale 1904711:10 AM Milan Centrale
4h04
3:14 PM Siena station2 transfers
frecciarossaFRECCIAROSSA 9535+trenitaliaregRegionale 1821911:10 AM Milan Centrale
4h30
3:40 PM Siena station1 transfer

This is the last train of the day.

Find all the dates and times for this journey

Compare prices and tickets Milan Centrale to Siena by bus or train

Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

Tue
Feb 24
Wed
Feb 25
Thu
Feb 26
Fri
Feb 27
Sat
Feb 28
Sun
Mar 01
Mon
Mar 02

Why should you book Milan Centrale to Siena trains with Omio?

Italo as well as Frecciarossa, Intercity, Regionale, Intercity Notte and more offer trains services from Milan Centrale to Siena.
Omio is the only official third party seller for Italo tickets.

Why book with Omio vs Italo?

  • Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Intercity, Regionale or Intercity Notte to find the best option for your trip from Milan Centrale to Siena.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Italo with all available travel options, which are bus and train to ensure you get the best deal for traveling from Milan Centrale to Siena.

Journey information

Overview: Train from Milan Centrale to Siena

ItalyItaly
ItalyItaly
Icon of train

Trains from Milan Centrale to Siena run on average 31 times per day, taking around 4h 54m. Cheap train tickets for this journey start at €26 but you can travel from only €8 by bus.

The earliest train runs at 04:40, the last at 20:10. The fastest train covers the 294 km distance in 1h 55m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €8
Distance
294 km
Average train duration
4h 54m
Cheapest ticket price
€26
Trains per day
31
Fastest train
1h 55m
First train
04:40
Last train
20:10
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Bus from €8

Train companies: Italo, Frecciarossa, Intercity, Regionale, Intercity Notte from Milan Centrale to Siena trainsItalo, Frecciarossa, Intercity, Regionale, Intercity Notte trains will get you between Milan Centrale and Siena from €8. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.

Italo

About
Italo is Italy’s private high-speed train service operated by Nuovo Trasporto Viaggiatori (NTV), connecting major cities such as Rome, Milan, Naples, Florence, Turin, Bologna, and Salerno. Its fleet includes the Italo AGV 575, capable of speeds up to 186 mph (300 km/h), and the eco-friendly Italo EVO, which reaches up to 150 mph (250 km/h). Passengers can choose from four classes — Smart, Comfort, Prima, and Club Executive — all offering modern amenities such as free Wi-Fi, power outlets, reclining leather seats, footrests, bathrooms, snack machines, and Italo Live entertainment with movies, music, and games. Italo offers three fare types — Low Cost, Economy, and Flex — providing different levels of price and flexibility. Popular routes include Rome–Milan, Rome–Florence, and Milan–Turin, making Italo a fast, comfortable, and convenient way to travel around Italy.
Luggage & cancellation policy
Average Duration
1h 55m
Cheapest Price
€50
Luggage included
2 pieces of hand luggage (max 55x35x25cm) and 1 piece of luggage (max 75x53x30cm)
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
Cancellation possible according to ticket conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Snack bar service available in most trains with drinks and light refreshments. Welcome service in Prima and Club Executive classes
Seat reservation
Included in Prima and Club Executive. Optional extra cost in Smart and Comfort
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs travel free
Quiet zone

Frecciarossa

About
Step on board a Frecciarossa train and relax as you travel across Italy. Trenitalia’s Frecciarossa high-speed trains make around 200 connections across the country each day and are renowned for their comfort, speed, and reduced environmental impact. Reaching speeds of up to 186 mph (300 km/h), they connect major destinations such as Rome, Florence, Milan, Venice, and Naples quickly and efficiently. When booking your Frecciarossa journey, you can choose between four classes: Standard, Premium, Business, and Executive. While each class offers different levels of comfort, all provide free Wi-Fi access, power outlets, air conditioning, bathrooms, luggage storage, onboard entertainment, and restaurant and bar services. Ticket options include Super Economy, Economy, and Base, making it easy to find the right balance of comfort and price for your trip.
Luggage & cancellation policy
Average Duration
6h 51m
Cheapest Price
€40
Frecciarossa frequency
18 a day
Luggage included
1 carry-on bag and 1 suitcase per passenger
Luggage storage
Overhead racks, dedicated luggage areas at carriage ends, under seats
Cancellation Policy
Refund policy depends on ticket type
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full meals, bar service with snacks and beverages, at-seat service in Executive class
Seat reservation
Included in Executive class, optional fee for other classes
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, assistance service available
Pets
Small pets in carriers travel free, larger dogs require paid ticket and muzzle, service animals free
Quiet zone

Intercity

About
Trenitalia Intercity is a high-speed train service operated by the Italian national railway company, Trenitalia. It operates throughout the country, with services running from early morning to late evening. The Intercity trains come in two types: the Intercity Plus, which is the fastest and most comfortable, and the Intercity, which is slightly slower but still offers a comfortable journey. Onboard facilities include air conditioning, power sockets, Wi-Fi, and a bar service. There are several ticket types available, including Standard, Super Economy, and Business. The most popular routes for Trenitalia Intercity are from Rome to Milan, Naples to Florence, and Turin to Venice.
Luggage & cancellation policy
Average Duration
5h 35m
Cheapest Price
€26
Luggage included
2 pieces of luggage up to 30kg total
Luggage storage
Overhead racks and designated luggage areas at end of carriages
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with hot meals and snacks, trolley service in some trains. But do not count on the presence of a buffet car. So if having access to food and drink on the train is important to you, it’s best to bring your own refreshments onboard.
Seat reservation
Seat reservation included in ticket price for most routes
Toilets
USB plugs
Accessibility
Wheelchair spaces and accessible toilets available
Pets
Small pets in carriers allowed free, larger dogs require paid ticket
Quiet zone

Regionale

About
Regionale is the regional train service of national carrier Trenitalia connecting all of Italy. It is the most convinient way to travel to both big cities and the smallest villages all over the Italian country. The regional trains have different names depending on the region they serve, such as Treno Regionale Veloce (TRV) and Treno Regionale Lento (TRL). Treno Rock and Treno pop are the two new trains part of Trenitalia regionale fleet. Trenitalia Regionale offers a variety of ticket types, including single tickets (economy and standard), return tickets, and season tickets. Onboard facilities include free Wi-Fi, air conditioning, and power sockets. The most popular routes for Regionale are between Rome and Milan, Naples and Florence, and Turin and Venice.
Luggage & cancellation policy
Average Duration
6h 50m
Cheapest Price
€32
Luggage included
Free hand luggage allowance included in ticket price
Luggage storage
Overhead racks and designated luggage areas between seats
Cancellation Policy
According to ticket conditions
Refund
Full refund provided
Amenities on board the train
Wifi
Food sold onboard
Bar service available on some trains with snacks and beverages
Seat reservation
Seat reservation included in ticket price for most services
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for passengers with reduced mobility
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle
Quiet zone

Intercity Notte

About
Intercity Notte is an Italian train service operated by Trenitalia. It runs overnight services between major cities in Italy, making it a great option for travelers looking to save time and money. The Intercity Notte offers two types of trains: the Frecciarossa Notte and the Frecciargento Notte. The Frecciarossa Notte is the fastest train, with speeds of up to 300 km/h, while the Frecciargento Notte is slightly slower but still offers a comfortable journey. Both trains offer a range of onboard facilities, including comfortable seating, air conditioning, and Wi-Fi. Trenitalia offers a range of ticket types, including Standard, Comfort, and Business. Standard tickets are the most affordable, while Comfort and Business tickets offer additional benefits such as priority boarding and access to the lounge. The most popular routes for Intercity Notte are Rome to Milan, Rome to Venice, and Milan to Venice. These routes offer travelers the chance to explore some of Italy's most iconic cities in a convenient and comfortable way.
Luggage & cancellation policy
Average Duration
9h 38m
Cheapest Price
€66
Intercity Notte frequency
1 a day
Luggage included
1 handbag and 1 suitcase included in ticket price
Luggage storage
Luggage racks above seats and at carriage ends
Cancellation Policy
Cancellation possible according to ticket type conditions
Refund
Full refund provided for canceled trains
Amenities on board the train
Wifi
Food sold onboard
Restaurant car with full dining service and bar
Seat reservation
Seat reservation included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces and assistance available for disabled passengers
Pets
Small pets in carriers travel free. Larger dogs require paid ticket and muzzle. Guide dogs free.
Quiet zone

FAQs: Trains from Milan Centrale to Siena

Find answers to the most common questions about traveling from Milan Centrale to Siena by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

FAQs
Cheap train tickets from Milan Centrale to Siena can start from as little as €26 when you book in advance. The average train ticket price for Milan Centrale to Siena is €34; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by train from Milan Centrale to Siena is 1h 55m to travel the 294 km long route. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest train from Milan Centrale to Siena leaves at 4:40 AM. Plan your trip with the Journey Planner   from Omio.
The latest train from Milan Centrale to Siena leaves at 8:10 PM.
There are 31 trains a day from Milan Centrale to Siena which require at least one change with Italo, Frecciarossa, Intercity, Regionale, Intercity Notte. Schedules can vary on holidays or weekends with fewer trains.
Yes, there's a high-speed train to Siena. Take the fast train with Italo, Frecciarossa from Milan Centrale to Siena.
When taking a train from Milan Centrale to Siena, you can count on Italo, Frecciarossa, Intercity, Regionale, Intercity Notte for the best way to get you to Siena. You can also check all possible train companies who offer a service between Milan Centrale and Siena and compare the amenities they offer before buying a train ticket.
Yes, you can take a night train from Milan Centrale to Siena with Intercity Notte. Find all the info regarding night trains in Europe.
A day trip to Siena from Milan Centrale is worth doing with a journey time of 1h 55m each way. Check with Omio app the best way to travel.
The cheapest month for a train from Milan Centrale to Siena is November.
It's helpful to compare your options as there are 2 ways to travel between Milan Centrale and Siena including taking a bus and train.

popular train stations

Popular train stations from Milan Centrale to Siena

Milan
Siena
The major train station for departures in Milan is Milano Centrale. Find all the information you need to know about services, amenities and connections at Milano Centrale for your trip from Milan to Siena.
Amenities at train station
WifiWifi
LockersLockers
ParkingParking
DiningDining
ATMATM
TaxisTaxis
AccessibilityAccessibility
WCWC
HotelHotel
Ticket OfficeTicket Office
Bike ParkingBike Parking
Bike RentalBike Rental
Car RentalCar Rental
Information DeskInformation Desk
information
phone
Phone Number
ticketOfficeHours
Ticket Office Hours
  • Mon - Sun: 05:50 - 22:20
ticketOfficeHours
Distance to city center
2 km
Wifi
Wifi
  • Free WiFi in the station.
Lockers
Lockers
  • Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
Dining
Dining
  • Venchi
  • Panzera Coffee
  • Burger King
  • Bar Motta
  • Caffè Napoli
  • VyTA Boulangerie
  • Spontini
  • Starbucks
  • Dispensa Emilia
  • McDonald's
  • & many more
Accessibility
Accessibility
  • Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
Hotel
Hotel
  • Glam Hotel Milano
  • NYX MIlan
  • iQ Hotel Milano
Ticket Office
Ticket Office
  • Mon - Sun: 05:50 - 22:20
Information Desk
Information Desk
  • Located next to the ticket office on the ground floor in the shopping gallery.
Public transit options for Milano Centrale
  • Metro lines: M2 (green), M3 (yellow)
  • Tram lines: 1
  • Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
  • Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo

More options for your journey from Milan Centrale to Siena

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