The cheapest and fastest trains from Milan Centrale to Siena
Cheapest price
€36
Average price
€76
Fastest journey
4 h 2 m
Average duration
4 h 3 m
Trains per day
46
Distance
294 km
The best way to find a cheap train ticket from Milan Centrale to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Siena will cost around €76 if you buy it on the day, but the cheapest tickets can be found for only €36.
It's difficult to get from Milan Centrale to Siena without transferring at least 2 times.
Regionale 2293 · Regionale 18413 · Regionale 18217
Intercity 657+
Regionale 18413 · Regionale 18217
Intercity 665+
Regionale 18399 · Regionale 18223
Intercity 583+
Regionale 18209
Intercity 597+
ETRUSCHI LINE 18307 · Regionale 19051
FRECCIAROSSA 8807 · FRECCIAROSSA 1000 9415+
Regionale 18217
FRECCIAROSSA 8811 · FRECCIAROSSA 9421+
Regionale 18221
FRECCIAROSSA 9809 · FRECCIAROSSA 1000 9323+
Regionale 18225
FRECCIAROSSA 9535+
Regionale Veloce 4035 · Regionale 19047
FRECCIAROSSA 1000 9539+
ETRUSCHI LINE 4039 · Regionale 19049Travel Information
Compare bus and train for Milan Centrale to Siena
Omio recommends booking the train as it is the most popular option from Milan Centrale to Siena among Omio's users. If you are prioritising price take the bus with prices starting from €8. For those with little time consider booking a train which can get you there in 4h 54m. The ticket price range depends on the travel mode: a bus costs an average of €8, and a train costs an average of €26.
Distance: 294 km
Compare train with
Most popular Train | Bus |
|---|---|
€34 Average price | €15 Average price Cheapest |
5h 24m Average total duration Fastest 4h 54m Onboard + 30m Additional time* | 5h 37m Average total duration 5h 7m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Milan Centrale to Siena train times
The table below shows live departures for Milan Centrale to Siena trains for today, Monday, February 23. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:40 PM Milan Centrale | 5h36 | 10:16 PM Siena | 0 transfersDirect | |
| Tuesday, February 24 | |||||
FRECCIAROSSA 9505+ Tuscany Line 4013 · Regionale 19035 | 4:10 AM Milan Centrale | 4h07 | 8:17 AM Siena station | 2 transfers | |
FRECCIAROSSA 9505+ Regionale 18203 | 4:10 AM Milan Centrale | 4h28 | 8:38 AM Siena station | 1 transfer | |
FRECCIAROSSA 1000 9601 · FRECCIAROSSA 9401+ Regionale 18203 | 4:20 AM Milan Centrale | 4h18 | 8:38 AM Siena station | 2 transfers | |
Intercity 583+ Regionale 18209 | 5:05 AM Milan Centrale | 6h33 | 11:38 AM Siena station | 1 transfer | |
FRECCIAROSSA 1000 9511+ Regionale Veloce 4017 · Regionale 19037 | 5:10 AM Milan Centrale | 4h06 | 9:16 AM Siena station | 2 transfers | |
Intercity 651+ Regionale 18409 · Regionale 18209 | 5:10 AM Milan Centrale | 6h28 | 11:38 AM Siena station | 2 transfers | |
FRECCIAROSSA 1000 9511+ Regionale 18205 | 5:10 AM Milan Centrale | 4h30 | 9:40 AM Siena station | 1 transfer | |
Regionale Veloce 3013+ Intercity 505+ Regionale 19122 | 5:25 AM Milan Centrale | 9h05 | 2:30 PM Siena station | 2 transfers | |
Regionale 2293 · Regionale 18413 · Regionale 18217 | 5:50 AM Milan Centrale | 8h47 | 2:37 PM Siena station | 2 transfers | |
FRECCIAROSSA 9515+ Regionale 18207 | 6:10 AM Milan Centrale | 4h30 | 10:40 AM Siena station | 1 transfer | |
Intercity 657+ Regionale 18413 · Regionale 18217 | 7:05 AM Milan Centrale | 7h32 | 2:37 PM Siena station | 2 transfers | |
FRECCIAROSSA 9519+ Regionale 18209 | 7:10 AM Milan Centrale | 4h28 | 11:38 AM Siena station | 1 transfer | |
FRECCIAROSSA 9583+ ETRUSCHI LINE 4027 · Regionale 19039 | 8:10 AM Milan Centrale | 4h05 | 12:15 PM Siena station | 2 transfers | |
FRECCIAROSSA 9583+ Regionale 18211 | 8:10 AM Milan Centrale | 4h30 | 12:40 PM Siena station | 1 transfer | |
Intercity 659 · Intercity 511+ Regionale 19126 | 8:10 AM Milan Centrale | 9h03 | 5:13 PM Siena station | 2 transfers | |
FRECCIAROSSA 9527+ Regionale 18215 | 9:10 AM Milan Centrale | 4h30 | 1:40 PM Siena station | 1 transfer | |
FRECCIAROSSA 9527+ TUSCANY LINE 4029 · Regionale 19041 | 9:10 AM Milan Centrale | 4h06 | 1:16 PM Siena station | 2 transfers | |
FRECCIAROSSA 9587+ Tuscany Line 4033 · Regionale 19043 | 10:10 AM Milan Centrale | 4h07 | 2:17 PM Siena station | 2 transfers | |
FRECCIAROSSA 9587+ Regionale 18217 | 10:10 AM Milan Centrale | 4h27 | 2:37 PM Siena station | 1 transfer | |
FRECCIAROSSA 8807 · FRECCIAROSSA 1000 9415+ Regionale 18217 | 10:35 AM Milan Centrale | 4h02 | 2:37 PM Siena station | 2 transfers | |
Intercity 665+ Regionale 18399 · Regionale 18223 | 11:10 AM Milan Centrale | 6h30 | 5:40 PM Siena station | 2 transfers | |
FRECCIAROSSA 9535+ Regionale Veloce 4035 · Regionale 19047 | 11:10 AM Milan Centrale | 4h04 | 3:14 PM Siena station | 2 transfers | |
FRECCIAROSSA 9535+ Regionale 18219 | 11:10 AM Milan Centrale | 4h30 | 3:40 PM Siena station | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Siena by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Milan Centrale to Siena trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Intercity, Regionale or Intercity Notte to find the best option for your trip from Milan Centrale to Siena.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are bus and train to ensure you get the best deal for traveling from Milan Centrale to Siena.
Journey information
Overview: Train from Milan Centrale to Siena
Trains from Milan Centrale to Siena run on average 31 times per day, taking around 4h 54m. Cheap train tickets for this journey start at €26 but you can travel from only €8 by bus.
The earliest train runs at 04:40, the last at 20:10. The fastest train covers the 294 km distance in 1h 55m.
Distance 294 km |
Average train duration 4h 54m |
Cheapest ticket price €26 |
Trains per day 31 |
Fastest train 1h 55m |
First train 04:40 |
Last train 20:10 |
Train companies: Italo, Frecciarossa, Intercity, Regionale, Intercity Notte from Milan Centrale to Siena trainsItalo, Frecciarossa, Intercity, Regionale, Intercity Notte trains will get you between Milan Centrale and Siena from €8. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Intercity
Regionale
Intercity Notte
FAQs: Trains from Milan Centrale to Siena
Find answers to the most common questions about traveling from Milan Centrale to Siena by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Milan Centrale to Siena
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available near the station, open 24/7.
- Ristorante Il Vinaio
- Osteria Le Logge
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Italia
- NH Siena
- Hotel Minerva
- Located near the main entrance
- Located near the main entrance
- Free
- The station has a single-level layout with platforms accessible from the main hall.
- Bus: Several local and regional lines available
- Taxi: Available outside the station
Most popular train connections from Milan Centrale
More options for your journey from Milan Centrale to Siena
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