The cheapest and fastest trains from Milan Centrale to Siena
Cheapest price
€28
Average price
€35
Fastest journey
5 h 36 m
Average duration
5 h 53 m
Trains per day
8
Distance
294 km
The best way to find a cheap train ticket from Milan Centrale to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Siena will cost around €35 if you buy it on the day, but the cheapest tickets can be found for only €28.
Of the 8 trains that leave Milan Centrale for Siena on Mon, May 25, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, May 25 the direct trains cover the 294 km distance in an average of 5 h 53 m but if you time it right, some trains will get you there in just 5 h 36 m .
On Mon, May 25 the slowest trains will take 6 h 33 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
5:05 AM6h33Milan Centrale11:38 AMSiena€281One-way0 transfers
11:48 AM5h50Milan Centrale5:38 PMSiena€281One-way0 transfers
3:40 PM5h36Milan Centrale9:16 PMSiena€281One-way0 transfers
5:50 AM8h47Milan Centrale2:37 PMSiena€321One-way0 transfers
4:50 AM7h26Milan Centrale12:16 PMSiena€371One-way0 transfers
4:40 PM5h36Milan Centrale10:16 PMSiena€471One-way0 transfers
3:40 PM5h36Milan Centrale9:16 PMSiena€281One-way0 transfers
12:48 PM5h50Milan Centrale6:38 PMSiena€431One-way0 transfers
11:48 AM5h50Milan Centrale5:38 PMSiena€281One-way0 transfers
5:05 AM6h33Milan Centrale11:38 AMSiena€281One-way0 transfers
Travel Information
Compare bus and train for Milan Centrale to Siena
Omio recommends booking the train as it is the most popular option from Milan Centrale to Siena among Omio's users. If you are prioritising price take the bus with prices starting from €7. For those with little time consider booking a train which can get you there in 4h 44m. The ticket price range depends on the travel mode: a bus costs an average of €7, and a train costs an average of €21.
Distance: 294 km
Compare train with
Most popular Train | Bus |
|---|---|
€35 Average price | €12 Average price Cheapest |
5h 14m Average total duration Fastest 4h 44m Onboard + 30m Additional time* | 5h 43m Average total duration 5h 13m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Live departures
Milan Centrale to Siena train times
The table below shows live departures for Milan Centrale to Siena trains for today, Sunday, May 24. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
InterCityNotte 755 · InterCityNotte 770+ Regionale 19066 | 9:50 PM Milan Centrale | 9h38 | 7:28 AM Siena station | 2 transfers | |
| Monday, May 25 | |||||
![]() | 4:50 AM Milan Centrale | 7h26 | 12:16 PM Siena | 0 transfersDirect | |
![]() | 5:05 AM Milan Centrale | 6h33 | 11:38 AM Siena | 0 transfersDirect | |
![]() | 5:50 AM Milan Centrale | 8h47 | 2:37 PM Siena | 0 transfersDirect | |
![]() | 9:20 AM Milan Centrale | 7h20 | 4:40 PM Siena | 0 transfersDirect | |
![]() | 11:48 AM Milan Centrale | 5h50 | 5:38 PM Siena | 0 transfersDirect | |
![]() | 12:48 PM Milan Centrale | 5h50 | 6:38 PM Siena | 0 transfersDirect | |
![]() | 3:40 PM Milan Centrale | 5h36 | 9:16 PM Siena | 0 transfersDirect | |
![]() | 4:40 PM Milan Centrale | 5h36 | 10:16 PM Siena | 0 transfersDirect | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Siena by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
May 25
May 26
May 27
May 28
May 29
May 30
Jun 01
Jun 03
Jun 04
Jun 06
Jun 07
Jun 09
Jun 10
Jun 12
Why should you book Milan Centrale to Siena trains with Omio?
Why book with Omio vs Italo?
- Compare with other providers: On Omio, you can not only buy tickets for Italo, but also compare tickets for the likes of Frecciarossa, Regionale, Intercity or Intercity Notte to find the best option for your trip from Milan Centrale to Siena.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Italo with all available travel options, which are bus and train to ensure you get the best deal for traveling from Milan Centrale to Siena.
Journey information
Overview: Train from Milan Centrale to Siena
Trains from Milan Centrale to Siena run on average 31 times per day, taking around 4h 44m. Cheap train tickets for this journey start at €21 but you can travel from only €7 by bus.
The earliest train runs at 03:40, the last at 16:40. The fastest train covers the 294 km distance in 1h 55m.
Distance 294 km |
Average train duration 4h 44m |
Cheapest ticket price €21 |
Trains per day 31 |
Fastest train 1h 55m |
First train 3:40 AM |
Last train 4:40 PM |
Cheapest Month Nov |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Fri |
Least Busy Day Sun |
Train companies: Italo, Frecciarossa, Regionale, Intercity, Intercity Notte from Milan Centrale to Siena trainsItalo, Frecciarossa, Regionale, Intercity, Intercity Notte trains will get you between Milan Centrale and Siena from €7. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Regionale
Intercity
Intercity Notte
FAQs: Trains from Milan Centrale to Siena
Find answers to the most common questions about traveling from Milan Centrale to Siena by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Milan Centrale to Siena
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available near the station, open 24/7.
- Ristorante Il Vinaio
- Osteria Le Logge
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Italia
- NH Siena
- Hotel Minerva
- Located near the main entrance
- Located near the main entrance
- Free
- The station has a single-level layout with platforms accessible from the main hall.
- Bus: Several local and regional lines available
- Taxi: Available outside the station
Most popular train connections from Milan Centrale
More options for your journey from Milan Centrale to Siena
Here are some other resources that might have the information you need



