The cheapest and fastest trains from Milan Centrale to Siena
Cheapest price
€36
Average price
€71
Fastest journey
4 h 2 m
Average duration
4 h 3 m
Trains per day
44
Distance
294 km
The best way to find a cheap train ticket from Milan Centrale to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Siena will cost around €71 if you buy it on the day, but the cheapest tickets can be found for only €36.
It's difficult to get from Milan Centrale to Siena without transferring at least 2 times.
Intercity 597+
Tuscany Line 18687 · Regionale 18225
Intercity 583+
Tuscany Line 18665 · Regionale 18207
Intercity 599+
Regionale 18233
Intercity 1589+
Regionale 18833 · Regionale 18211
Regionale 2293 · Tuscany Line 18288 · Regionale 18211
FRECCIAROSSA 8807 · FRECCIAROSSA 1000 9415+
Regionale 18217
FRECCIAROSSA 9809 · FRECCIAROSSA 1000 9323+
Regionale 18225
FRECCIAROSSA 8811 · FRECCIAROSSA 9421+
Regionale 18221
FRECCIAROSSA 1000 9539+
TUSCANY LINE 4041 · Regionale 19049
FRECCIAROSSA 9535+
Regionale Veloce 4035 · Regionale 19047Travel Information
Compare bus, train, and flight for Milan Centrale to Siena
Omio recommends booking the train as it is the most popular option from Milan Centrale to Siena among Omio's users. If you are prioritising price take the bus with prices starting from €8. For those with little time consider booking a bus which can get you there in 4h 55m. The ticket price range depends on the travel mode: a bus costs an average of €8, and a flight costs an average of €142.
Distance: 294 km
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€39 Average price | €15 Average price Cheapest | €202 Average price |
5h 26m Average total duration 4h 56m Onboard + 30m Additional time* | 5h 25m Average total duration Fastest 4h 55m Onboard + 30m Additional time* | 12h 34m Average total duration 9h 34m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Milan Centrale to Siena train times
The table below shows live departures for Milan Centrale to Siena trains for today, Friday, January 9. You can also manually refresh the results below to see updated train journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 11:48 AM Milan Centrale | 5h50 | 5:38 PM Siena | 0 transfersDirect | |
![]() | 3:40 PM Milan Centrale | 6h22 | 10:02 PM Siena | 0 transfersDirect | |
| Saturday, January 10 | |||||
FRECCIAROSSA 9505+ Tuscany Line 4013 · Regionale 19035 | 4:10 AM Milan Centrale | 4h07 | 8:17 AM Siena station | 2 transfers | |
FRECCIAROSSA 9505+ Regionale 18203 | 4:10 AM Milan Centrale | 4h28 | 8:38 AM Siena station | 1 transfer | |
Intercity 583+ Tuscany Line 18665 · Regionale 18207 | 5:05 AM Milan Centrale | 5h35 | 10:40 AM Siena station | 2 transfers | |
FRECCIAROSSA 1000 9511+ Regionale Veloce 4017 · Regionale 19037 | 5:10 AM Milan Centrale | 4h06 | 9:16 AM Siena station | 2 transfers | |
FRECCIAROSSA 1000 9511+ Regionale 18205 | 5:10 AM Milan Centrale | 4h30 | 9:40 AM Siena station | 1 transfer | |
This is the last train of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Siena by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Jan 16
Journey information
Overview: Train from Milan Centrale to Siena
Trains from Milan Centrale to Siena run on average 30 times per day, taking around 4h 56m. Cheap train tickets for this journey start at €23 but you can travel from only €8 by bus.
The earliest train runs at 03:45, the last at 19:50. The fastest train covers the 294 km distance in 5h 36m.
Distance 294 km |
Average train duration 4h 56m |
Cheapest ticket price €23 |
Trains per day 30 |
Fastest train 5h 36m |
First train 03:45 |
Last train 19:50 |
Train companies: Italo, Frecciarossa, Intercity, Regionale, Intercity Notte from Milan Centrale to Siena trainsItalo, Frecciarossa, Intercity, Regionale, Intercity Notte trains will get you between Milan Centrale and Siena from €8. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
Italo
Frecciarossa
Intercity
Regionale
Intercity Notte
FAQs: Trains from Milan Centrale to Siena
Find answers to the most common questions about traveling from Milan Centrale to Siena by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

popular train stations
Popular train stations from Milan Centrale to Siena
- Mon - Sun: 05:50 - 22:20
- Free WiFi in the station.
- Provided by KiPoint and located on the ground floor, on the side of Piazza Luigi di Savoia. It is open every day from 06:00 to 23:00.
- Venchi
- Panzera Coffee
- Burger King
- Bar Motta
- Caffè Napoli
- VyTA Boulangerie
- Spontini
- Starbucks
- Dispensa Emilia
- McDonald's
- & many more
- Station is wheelchair accessible, has elevators and the Sala Blu, Trenitalia's office of assistance for disabled travelers, is next to Platform 4.
- Glam Hotel Milano
- NYX MIlan
- iQ Hotel Milano
- Mon - Sun: 05:50 - 22:20
- Located next to the ticket office on the ground floor in the shopping gallery.
- Metro lines: M2 (green), M3 (yellow)
- Tram lines: 1
- Bus lines: 5, 9, 10, 42, 81, 87, 152, 728, N26, NM2, NM3, Air Bus, Orio Shuttle
- Train lines: FR, FB, EC, Thello, XP2, R28, IC, ICN, RV, R, Regio, Italo
- 6:00 AM - 8:00 PM Monday - Sunday
- Free
- Parking is available near the station, open 24/7.
- Ristorante Il Vinaio
- Osteria Le Logge
- Outside the main entrance.
- Elevators, ramps.
- €1
- Hotel Italia
- NH Siena
- Hotel Minerva
- Located near the main entrance
- Located near the main entrance
- Free
- The station has a single-level layout with platforms accessible from the main hall.
- Bus: Several local and regional lines available
- Taxi: Available outside the station
Most popular train connections from Milan Centrale
More options for your journey from Milan Centrale to Siena
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