The cheapest and fastest buses from Milan Centrale to Siena
Cheapest price
€15
Average price
€19
Fastest journey
5 h 45 m
Average duration
5 h 53 m
Buses per day
5
Distance
294 km
The best way to find a cheap bus ticket from Milan Centrale to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan Centrale to Siena will cost around €19 if you buy it on the day, but the cheapest tickets can be found for only €15.
Of the 5 buses that leave Milan Centrale for Siena on Wed, Nov 26, 5 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Nov 26 the direct buses cover the 294 km distance in an average of 5 h 53 m but if you time it right, some buses will get you there in just 5 h 45 m .
On Wed, Nov 26 the slowest buses will take 6 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare bus, train, and flight for Milan Centrale to Siena
Omio recommends booking the train as it is the most popular option from Milan Centrale to Siena among Omio's users. If you are prioritising price take the bus with prices starting from €8. For those with little time consider booking a bus which can get you there in 4h 55m. The ticket price range depends on the travel mode: a bus costs an average of €8, and a flight costs an average of €142.
Distance: 294 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€15 Average price Cheapest | €39 Average price | €202 Average price |
5h 25m Average total duration Fastest 4h 55m Onboard + 30m Additional time* | 5h 26m Average total duration 4h 56m Onboard + 30m Additional time* | 12h 34m Average total duration 9h 34m Onboard + 3h 0m Additional time* |
Direct Options | Direct Options | Direct Options |
Live departures
Milan Centrale to Siena bus times
The table below shows live departures for Milan Centrale to Siena buses for today, Tuesday, November 25. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
2499 | 5:00 AM Milano, Autostazione Lampugnano | 6h05 | 11:05 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 7:15 AM Milano, Autostazione Lampugnano | 7h25 | 2:40 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 7:20 AM Milano, Autostazione Lampugnano | 6h35 | 1:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 8:05 AM Assago, Viale Milanofiori (Assago M2) | 5h50 | 1:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
2125 · 2401 | 10:15 AM Milano, Autostazione Lampugnano | 7h30 | 5:45 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 1 transfer | |
FlixBus | 11:25 AM Milano, Autostazione Lampugnano | 5h50 | 5:15 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 2:30 PM Milano, Autostazione Lampugnano | 5h45 | 8:15 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 3:20 PM Milano, Autostazione Lampugnano | 6h00 | 9:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 4:05 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 5h15 | 9:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
2495 | 9:40 PM Milano, Autostazione Lampugnano | 6h30 | 4:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
3825 | 10:55 PM Milano, Autostazione Lampugnano | 6h05 | 5:00 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Milan Centrale to Siena by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Milan Centrale to Siena
Buses from Milan Centrale to Siena run on average 15 times per day, taking around 4h 55m. Cheap bus tickets for this journey start at €8 if you book in advance.
There are 13 buses per day. The earliest bus runs at 04:15, the last at 21:45. The fastest bus covers the 294 km distance in 5h 0m.
Distance 294 km |
Average bus duration 4h 55m |
Cheapest ticket price €8 |
Buses per day 15 |
Direct buses 13 |
Fastest bus 5h 0m |
First bus 04:15 |
Last bus 21:45 |
Bus providers: FlixBus, BlaBlaCar, Itabus from Milan Centrale to SienaYou can travel by bus between Milan Centrale to Siena with FlixBus, BlaBlaCar, Itabus for as low as €8. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
BlaBlaCar
FAQs: Bus from Milan Centrale to Siena
Find answers to the most common questions about traveling from Milan Centrale to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

To find the cheapest bus tickets for your trip from Milan Centrale to Siena, follow these tips:
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