Travel Information
Compare train, bus, and flight for Nantes to Lyon
Omio recommends booking the train as it is the most popular option from Nantes to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €22. For those with little time consider booking a flight which can get you there in 1h 23m. The ticket price range depends on the travel mode: a bus costs an average of €22, and a flight costs an average of €48.
Distance: 516 km
Compare train with
Most popular Train | Flight | Bus |
|---|---|---|
€80 Average price | €120 Average price | €50 Average price Cheapest |
6h 49m Average total duration 6h 19m Onboard + 30m Additional time* | 4h 23m Average total duration Fastest 1h 23m Onboard + 3h 0m Additional time* | 9h 13m Average total duration 8h 43m Onboard + 30m Additional time* |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company |
Direct Options | Direct Options | Direct Options |
Travel optionsfrom Nantes to Lyon
How to get from Nantes to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Nantes to Lyon is by taking a bus because it’s the best combination of price and speed.
88094 · 5010711:55 AM12h25Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes12:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€501One-way1 transfer
Cheapest
88094 · 5010711:55 AM12h25Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes12:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€501One-way1 transfer
Fastest
U247117:00 PM1h10Nantes Atlantique Airport8:10 PMLyon Saint Exupery Airport€2011One-way0 transfers
Other options
44062:46 PM6h40Nantes station9:26 PMLyon Part Dieu€861One-way0 transfers
53004:50 AM4h40Nantes station9:30 AMLyon Part Dieu€981One-way0 transfers
12402+
8573026:44 AM4h46Nantes station11:30 AMLyon Part Dieu€1191One-way1 transfer
50816 · 47811:40 PM12h00Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes1:40 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€551One-way1 transfer
87086 · 47875:00 PM12h25Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes5:25 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€551One-way1 transfer
87086 · 508835:00 PM12h25Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes5:25 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€551One-way1 transfer
AF614310:35 AM1h15Nantes Atlantique Airport11:50 AMLyon Saint Exupery Airport€2891One-way0 transfers
AF7507 · AF73706:45 PM3h15Nantes Atlantique Airport10:00 PMLyon Saint Exupery Airport€4101One-way1 transfer
LH2243 · LH22466:20 PM14h30Nantes Atlantique Airport8:50 AMLyon Saint Exupery Airport€4401One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Nantes to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Nantes to Lyon.

This is compared to other travel options from Nantes to Lyon:
A bus is €31 less than a train for this route with tickets for a train from Nantes to Lyon costing on average €80.
A bus is €70 less than a flight for this route with tickets for a flight from Nantes to Lyon costing on average €120.
Other travel options to Lyon take longer:
Train takes on average 6h 19m.
Bus takes on average 8h 43m.
- Around 11 trains per day.
- Around 11 buses per day.
- Around 10 flights per day.
However, we recommend checking specific travel dates for your route between Nantes and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Nantes Atlantique Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Nantes station and arrive in Lyon Part Dieu.
- Buses mostly depart from Nantes, Route de Paris and arrive in Lyon, Perrache Bus Station.
- Travel with easyJet, Volotea, Air France to go to Lyon by flight.
- Travel with SNCF | Intercités, SNCF | TGV INOUI, TGV, Société Nationale des Chemins de fer Français (SNCF) to go to Lyon by train.
- Travel with FlixBus, BlaBlaCar Bus, BlaBlaCar, Naolib to go to Lyon by bus.
- 2 direct flights per day with easyJet, Volotea, Air France.
- 4 direct trains per day with SNCF | Intercités, SNCF | TGV INOUI, Société Nationale des Chemins de fer Français (SNCF).
- 4 direct buses per day with FlixBus, BlaBlaCar Bus, BlaBlaCar.
Travelling from Nantes to Lyon: related information
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