Travel Information
Compare train, bus, and flight for Nantes to Lyon
Omio recommends booking the train as it is the most popular option from Nantes to Lyon among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €58 For those with little time, consider booking a flight, which has an average total journey time of 4h 15m. Average ticket prices depend on the travel mode: a bus costs an average of €58, while a flight costs an average of €384.
Distance: 516 km
Compare train with
Most popular Train | Flight | Bus | Driving |
|---|---|---|---|
€123 Average price | €384 Average price | €58 Average price Cheapest | €181 Average price (fuel + tolls) |
5h 17m Average total duration 4h 47m Onboard + 30m Additional time* | 4h 15m Average total duration Fastest 2h 15m Onboard + 2h 0m Additional time* | 11h 29m Average total duration 10h 59m Onboard + 30m Additional time* | 6h 34m Average total duration (door-to-door) |
![]() Most popular train company | ![]() Most popular airline | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options | Direct Options |
Compare ways to travel from Nantes to Lyon
Compare the available ways to get from Nantes to Lyon, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Nantes to Lyon:
A bus is €65 less than a train for this route with tickets for a train from Nantes to Lyon costing on average €123.
A bus is €327 less than a flight for this route with tickets for a flight from Nantes to Lyon costing on average €384.
Other travel options to Lyon take longer:
Train takes on average 5h 17m.
Bus takes on average 11h 29m.
Travel optionsfrom Nantes to Lyon
How to get from Nantes to Lyon by train, bus or flight.
Our recommendation
The best way to travel from Nantes to Lyon is by taking a bus because it’s the best combination of price and speed.
88094 · 5010711:55 AM12h25Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes12:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€461One-way1 transfer
Cheapest
88094 · 5010711:55 AM12h25Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes12:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€461One-way1 transfer
Fastest
U243309:55 PM1h10Nantes Atlantique Airport11:05 PMLyon Saint Exupery Airport€1141One-way0 transfers
Other options
44026:26 AM6h38Nantes station1:04 PMLyon Part Dieu€861One-way0 transfers
44062:46 PM6h40Nantes station9:26 PMLyon Part Dieu€861One-way0 transfers
53004:47 AM4h43Nantes station9:30 AMLyon Part Dieu€931One-way0 transfers
FlixBus · FlixBus1:40 PM12h40Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes2:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€621One-way1 transfer
FlixBus · FlixBus12:30 AM14h15Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes2:45 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€621One-way1 transfer
FlixBus · FlixBus12:20 AM12h35Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes12:55 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€631One-way1 transfer
U243289:00 AM1h15Nantes Atlantique Airport10:15 AMLyon Saint Exupery Airport€1221One-way0 transfers
LH1057 · LH10827:15 PM4h15Nantes Atlantique Airport11:30 PMLyon Saint Exupery Airport€1791One-way1 transfer
LH1057 · LH10767:15 PM18h40Nantes Atlantique Airport1:55 PMLyon Saint Exupery Airport€1981One-way1 transfer
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Nantes to Lyon
Travel to Lyon easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Nantes to Lyon.

This is compared to other travel options from Nantes to Lyon:
A bus is €65 less than a train for this route with tickets for a train from Nantes to Lyon costing on average €123.
A bus is €327 less than a flight for this route with tickets for a flight from Nantes to Lyon costing on average €384.
Other travel options to Lyon take longer:
Train takes on average 5h 17m.
Bus takes on average 11h 29m.
- Around 13 flights per day.
- Around 13 trains per day.
- Around 11 buses per day.
However, we recommend checking specific travel dates for your route between Nantes and Lyon as scheduled services by train, bus, and flight can vary by season or day of the week.
- Flights mostly depart from Nantes Atlantique Airport and arrive in Lyon Saint Exupery Airport.
- Trains mostly depart from Nantes station and arrive in Lyon Part Dieu.
- Buses mostly depart from Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes and arrive in Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
- Travel with easyJet, Volotea, Air France, CitizenPlane, Lufthansa, Air Baltic to go to Lyon by flight.
- Travel with FlixBus, BlaBlaCar Bus, Infobus to go to Lyon by bus.
- Travel with SNCF | Intercités, SNCF | TGV INOUI, SNCF | Intercités de nuit to go to Lyon by train.
- 2 direct flights per day with easyJet, Volotea, Air France, CitizenPlane.
- 2 direct buses per day with FlixBus, BlaBlaCar Bus.
- 4 direct trains per day with SNCF | Intercités, SNCF | TGV INOUI.
Travelling from Nantes to Lyon: related information
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