The cheapest and fastest buses from Nantes to Lyon
Cheapest price
€48
Average price
€71
Fastest journey
9 h 10 m
Average duration
10 h 35 m
Buses per day
18
Distance
516 km
The best way to find a cheap bus ticket from Nantes to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Nantes to Lyon will cost around €71 if you buy it on the day, but the cheapest tickets can be found for only €48.
Of the 18 buses that leave Nantes for Lyon on Mon, Aug 03, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Aug 03 the direct buses cover the 516 km distance in an average of 10 h 35 m but if you time it right, some buses will get you there in just 9 h 10 m .
On Mon, Aug 03 the slowest buses will take 12 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
87086 · 51335:00 PM12h20Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes5:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€481One-way1 transfer
87086 · 508835:00 PM12h25Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes5:25 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€481One-way1 transfer
87086 · 47875:00 PM12h25Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes5:25 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€481One-way1 transfer
88094 · 5010711:55 AM12h25Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes12:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€531One-way1 transfer
90400 · 74655:25 PM12h45Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes6:10 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€581One-way1 transfer
7240411:35 PM9h10Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes8:45 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€601One-way0 transfers
FlixBus8:10 AM10h05Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes6:15 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€641One-way0 transfers
FlixBus8:35 PM10h15Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes6:50 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€601One-way0 transfers
4031 · 517085:30 AM11h25Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes4:55 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€1151One-way1 transfer
50816 · 47811:40 PM12h00Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes1:40 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€581One-way1 transfer
Travel Information
Compare train, bus, and flight for Nantes to Lyon
Omio recommends booking the train as it is the most popular option from Nantes to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €22. For those with little time consider booking a flight which can get you there in 1h 23m. The ticket price range depends on the travel mode: a bus costs an average of €22, and a flight costs an average of €48.
Distance: 516 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€50 Average price Cheapest | €80 Average price | €120 Average price |
9h 13m Average total duration 8h 43m Onboard + 30m Additional time* | 6h 49m Average total duration 6h 19m Onboard + 30m Additional time* | 4h 23m Average total duration Fastest 1h 23m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Nantes to Lyon bus times
The table below shows live departures for Nantes to Lyon buses for today, Sunday, August 2. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
72404 | 11:35 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 9h10 | 8:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| Monday, August 3 | |||||
FlixBus · FlixBus | 12:20 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h35 | 12:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 12:30 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 14h15 | 2:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
4031 · 51708 | 5:30 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 11h25 | 4:55 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 8:10 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 10h05 | 6:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
FlixBus · FlixBus | 10:10 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 13h05 | 11:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 10:45 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 13h05 | 11:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
88094 · 50107 | 11:55 AM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h25 | 12:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 12:40 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 14h30 | 3:10 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
50816 · 4781 | 1:40 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h00 | 1:40 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 4:30 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h05 | 4:35 AM Lyon | 1 transfer | |
FlixBus · FlixBus | 4:30 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h20 | 4:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
87086 · 5133 | 5:00 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h20 | 5:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
87086 · 50883 | 5:00 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h25 | 5:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
87086 · 4787 | 5:00 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h25 | 5:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
90400 · 7465 | 5:25 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h45 | 6:10 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 5:45 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 12h10 | 5:55 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 8:35 PM Pôle d'échange multimodal Gare Sud SNCF, 44000 Nantes | 10h15 | 6:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Nantes to Lyon by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Aug 03
Aug 04
Aug 05
Aug 06
Aug 07
Aug 08
Aug 09
Aug 10
Aug 11
Aug 12
Aug 13
Aug 14
Aug 15
Aug 16
Aug 17
Aug 18
Aug 19
Aug 20
Aug 21
Aug 22
Aug 23
Why should you book Nantes to Lyon buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of BlaBlaCar Bus or Naolib to find the best option for your trip from Nantes to Lyon.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Nantes to Lyon.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of BlaBlaCar Bus or Naolib to find the best option for your trip from Nantes to Lyon.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Nantes to Lyon.
Journey information
Overview: Bus from Nantes to Lyon
Buses from Nantes to Lyon run on average 11 times per day, taking around 8h 43m. Cheap bus tickets for this journey start at €22 if you book in advance.
There are 4 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 516 km distance in 9h 10m.
Distance 516 km |
Average bus duration 8h 43m |
Cheapest ticket price €22 |
Buses per day 11 |
Direct buses 4 |
Fastest bus 9h 10m |
First bus 12:05 AM |
Last bus 11:55 PM |
Cheapest Month Oct |
Cheapest Day Sat |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sun |
Best time to book 77 days |
Bus providers: FlixBus, BlaBlaCar Bus, BlaBlaCar, Naolib from Nantes to LyonYou can travel by bus between Nantes to Lyon with FlixBus, BlaBlaCar Bus, BlaBlaCar, Naolib for as low as €22. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
BlaBlaCar
Naolib
FAQs: Bus from Nantes to Lyon
Find answers to the most common questions about traveling from Nantes to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Nantes to Lyon
Most Nantes to Lyon buses use the Nantes, Route de Paris to Lyon, Gare Routière de Perrache station pair, with some services arriving at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan). Use this guide to compare Nantes and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Nantes station do buses to Lyon leave from?
Getting to Nantes, Route de Paris from Nantes city centre
Nantes, Route de Paris is 4 km from Nantes city centre. Public transport options include:
Nantes, Route de Paris bus station facilities and services
Nantes, Route de Paris has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Café de la Gare (in the station), Fast Food Express (in the station).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance.
Tickets and information
Ticket office support is available at Nantes, Route de Paris.
Parking, taxis and toilets
Available at Nantes, Route de Paris: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Nantes, Route de Paris: Elevators, ramps.
Getting to Nantes, Gare SNCF Sud from Nantes city centre
Which Lyon station do buses from Nantes arrive at?
Getting to Lyon, Gare Routière de Perrache from Lyon city centre
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache bus station facilities and services
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance.
Tickets and information
Ticket office support is available at Lyon, Gare Routière de Perrache.
Parking, taxis and toilets
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Getting to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) from Lyon city centre
Getting to Lyon, St Exupéry Aéroport from Lyon city centre
Most popular bus connections from Nantes
More options for your journey from Nantes to Lyon
Here are some other resources that might have the information you need


