Travel Information
Compare bus, train, and flight for Santander to Madrid
Omio recommends booking the train as it is the most popular option from Santander to Madrid among Omio's users. If you are prioritising price take the train with prices starting from €16. For those with little time consider booking a flight which can get you there in 2h 41m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a train costs an average of €16, and a flight costs an average of €49.
Distance: 339 km
Compare train with
Most popular Train | Bus | Flight |
|---|---|---|
€31 Average price Cheapest | €54 Average price | €254 Average price |
4h 47m Average total duration 4h 17m Onboard + 30m Additional time* | 6h 22m Average total duration 5h 52m Onboard + 30m Additional time* | 5h 41m Average total duration Fastest 2h 41m Onboard + 3h 0m Additional time* |
0.1 - 0.3kg CO2 emissions Lowest | 0.3 - 0.8kg CO2 emissions | 1.0 - 2.0kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Santander to Madrid
How to get from Santander to Madrid by train, bus or flight.
Our recommendation
The best way to travel from Santander to Madrid is by taking a bus because it’s the best combination of price and speed.
Normal5:30 PM5h30Santander, Estación de Autobuses11:00 PMMadrid, Intercambiador de Avenida de América€391One-way0 transfers
Cheapest
Normal5:30 PM5h30Santander, Estación de Autobuses11:00 PMMadrid, Intercambiador de Avenida de América€391One-way0 transfers
Fastest
IB106010:05 AM1h10Santander Airport11:15 AMMadrid Barajas Airport€2481One-way0 transfers
Other options
18102+
051789:20 AM7h24Santander station4:44 PMMadrid Chamartín€441One-way1 transfer
04072+
180106:48 AM6h37Santander station1:25 PMMadrid Príncipe Pío€461One-way1 transfer
18102+
180049:20 AM8h09Santander station5:29 PMMadrid Príncipe Pío€501One-way1 transfer
Normal8:00 AM5h40Santander, Estación de Autobuses1:40 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)€411One-way0 transfers
Normal8:00 AM5h50Santander, Estación de Autobuses1:50 PMMadrid, Intercambiador de Avenida de América€411One-way0 transfers
Normal10:30 AM6h15Santander, Estación de Autobuses4:45 PMMadrid, Intercambiador de Avenida de América€411One-way0 transfers
IB10645:40 PM1h10Santander Airport6:50 PMMadrid Barajas Airport€3221One-way0 transfers
IB10666:30 AM1h10Santander Airport7:40 AMMadrid Barajas Airport€3261One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Santander to Madrid
Travel to Madrid easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Santander to Madrid.

This is compared to other travel options from Santander to Madrid:
A train is €22 less than a bus for this route with tickets for a bus from Santander to Madrid costing on average €54.
A train is €222 less than a flight for this route with tickets for a flight from Santander to Madrid costing on average €254.
Other travel options to Madrid take longer:
Train takes on average 4h 17m.
Bus takes on average 5h 52m.
- Around 15 buses per day.
- Around 3 flights per day.
- Around 3 trains per day.
However, we recommend checking specific travel dates for your route between Santander and Madrid as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Santander Airport and arrive in Madrid Barajas Airport.
- Trains mostly depart from Santander station and arrive in Madrid Chamartín.
- Buses mostly depart from Santander, Estación de Autobuses and arrive in Madrid, Intercambiador de Avenida de América.
- Travel with Alsa, Alsa Supra, BlaBlaCar, FlixBus to go to Madrid by bus.
- Travel with Renfe ALVIA, Renfe INTERCITY, Renfe, Renfe MD, Renfe Viajeros to go to Madrid by train.
- Travel with Iberia, Air Nostrum, Vueling, Air Europa to go to Madrid by flight.
- 12 direct buses per day with Alsa, Alsa Supra, BlaBlaCar.
- 3 direct trains per day with Renfe ALVIA, Renfe INTERCITY, Renfe Viajeros.
- 3 direct flights per day with Iberia, Air Nostrum.
Travelling from Santander to Madrid: related information
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