The cheapest and fastest buses from Santander to Madrid
Cheapest price
€23
Average price
€45
Fastest journey
4 h
Average duration
4 h 16 m
Buses per day
15
Distance
339 km
The best way to find a cheap bus ticket from Santander to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santander to Madrid will cost around €45 if you buy it on the day, but the cheapest tickets can be found for only €23.
Of the 15 buses that leave Santander for Madrid on Sun, Feb 15, 12 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Feb 15 the direct buses cover the 339 km distance in an average of 4 h 16 m but if you time it right, some buses will get you there in just 4 h .
On Sun, Feb 15 the slowest buses will take 4 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.










Travel Information
Compare train, bus, and flight for Santander to Madrid
Omio recommends booking the train as it is the most popular option from Santander to Madrid among Omio's users. If you are prioritising price take the train with prices starting from €23. For those with little time consider booking a flight which can get you there in 2h 42m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a train costs an average of €23, and a flight costs an average of €28.
Distance: 339 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€42 Average price | €40 Average price Cheapest | €239 Average price |
6h 48m Average total duration 6h 18m Onboard + 30m Additional time* | 4h 47m Average total duration 4h 17m Onboard + 30m Additional time* | 5h 42m Average total duration Fastest 2h 42m Onboard + 3h 0m Additional time* |
0.3 - 0.8kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 1.0 - 2.0kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Santander to Madrid bus times
The table below shows live departures for Santander to Madrid buses for today, Saturday, February 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Supra Economy | 2:30 PM Santander, Estación de Autobuses | 5h00 | 7:30 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 0 transfersDirect | |
Supra Economy | 2:30 PM Santander, Estación de Autobuses | 5h15 | 7:45 PM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
Normal · Normal | 3:00 PM Santander, Estación de Autobuses | 6h45 | 9:45 PM Madrid, Calle de la Princesa / Paseo de Moret (Moncloa) | 1 transfer | |
Normal | 4:30 PM Santander, Estación de Autobuses | 5h30 | 10:00 PM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
FlixBus · FlixBus | 5:50 PM Santander, Estación de Autobuses | 18h30 | 12:20 PM Madrid, Estación Sur de Autobuses | 1 transfer | |
Supra Economy | 11:45 PM Santander, Estación de Autobuses | 5h30 | 5:15 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 0 transfersDirect | |
Supra Economy | 11:45 PM Santander, Estación de Autobuses | 5h45 | 5:30 AM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
| Sunday, February 15 | |||||
Normal | 12:00 AM Santander, Estación de Autobuses | 5h15 | 5:15 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 0 transfersDirect | |
Normal | 12:00 AM Santander, Estación de Autobuses | 5h30 | 5:30 AM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
FlixBus · FlixBus | 8:25 AM Santander, Estación de Autobuses | 21h45 | 6:10 AM Madrid, Estación Sur de Autobuses | 1 transfer | |
Normal | 9:30 AM Santander, Estación de Autobuses | 6h15 | 3:45 PM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Santander to Madrid by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 14
Feb 15
Feb 16
Feb 17
Feb 18
Feb 19
Feb 20
Feb 21
Feb 22
Feb 23
Feb 24
Feb 25
Feb 26
Feb 27
Feb 28
Mar 01
Mar 02
Mar 03
Mar 04
Mar 05
Mar 06
Journey information
Overview: Bus from Santander to Madrid
Buses from Santander to Madrid run on average 15 times per day, taking around 6h 19m. Cheap bus tickets for this journey start at €32 but you can travel from only €23 by train.
There are 12 buses per day. The earliest bus runs at 00:30, the last at 23:45. The fastest bus covers the 339 km distance in 5h 30m.
Distance 339 km |
Average bus duration 6h 19m |
Cheapest ticket price €32 |
Buses per day 15 |
Direct buses 12 |
Fastest bus 5h 30m |
First bus 00:30 |
Last bus 23:45 |
Bus providers: Alsa, Alsa Supra, BlaBlaCar, FlixBus from Santander to MadridYou can travel by bus between Santander to Madrid with Alsa, Alsa Supra, BlaBlaCar, FlixBus for as low as €23. When you search for schedules and tickets, Omio will show you the best journey
Alsa
Alsa Supra
FlixBus
BlaBlaCar
FAQs: Bus from Santander to Madrid
Find answers to the most common questions about traveling from Santander to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

- Alsa
- Assistance
- Priority boarding
- Accessible seating.
- Alsa Supra
- Assistance
- Priority boarding
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Alsa
- You can cancel your ticket up to 48 hours before departure for a partial refund. Changes allowed for a fee.
- Alsa Supra
- You can cancel your ticket up to 48 hours before departure for a partial refund. Within 48 hours, a fee applies.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Alsa
- One carry-on bag up to 10kg and one checked bag up to 25kg.
- Alsa Supra
- One carry-on bag up to 10kg and one checked bag up to 25kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Alsa
- Additional luggage can be purchased for a fee.
- Alsa Supra
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Alsa
- Small pets allowed in carriers
- larger pets must travel in the hold.
- Alsa Supra
- Small pets allowed in carriers
- guide dogs travel for free.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Santander to Madrid
- 06:00-23:00
- Free Wi-Fi
- Cafetería de la estación (in the station)
- Restaurante El Rincón (0.5 km)
- La Vaca Argentina (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 200, 114, 115, 122 Metro: 4, 6, 7, 9
- 06:00-23:00
- Rodilla, Mahoudrid
- Step-free access, elevators, accessible toilets
- Located inside the terminal, well-signposted, accessible, and generally clean
- No public showers in the bus station area; showers available in airport lounges (approx. €15-€30 for lounge access)
- Metro Line 8, Aeropuerto T4, 12 km
- 06:00-23:00
- Free Wi-Fi
- Cafetería de la estación (in the station)
- Restaurante El Brillante (0.5 km)
- La Taberna de Domínguez (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 8, 102, 148 Metro: L6 Train: C1, C5
Most popular bus connections from Santander
More options for your journey from Santander to Madrid
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