Santander to Madrid bus with Alsa

Tue, Sep 29
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Alsa
Alsa Supra
FlixBus
Avanza
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2,000+ travel companies
Alsa
Alsa Supra
FlixBus
Avanza
BlaBlaCar Bus
2,000+ travel companies
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The cheapest and fastest buses from Santander to Madrid

Showing times, prices and bookable tickets for Sep 29

Cheapest price on Sep 29

€36

Average ticket price on Sep 29

€49

Fastest journey on Sep 29

5 h

Average journey duration on Sep 29

5 h 21 m

Buses on Sep 29

13

Distance

339 km

Cheap tickets

The best way to find a cheap bus ticket from Santander to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Santander to Madrid will cost around €49 if you buy it on the day, but the cheapest tickets can be found for only €36.

Fast buses

On Tue, Sep 29, we found 13 buses from Santander to Madrid, including 10 direct services.

On Tue, Sep 29 the direct buses cover the 339 km distance in an average of 5 h 21 m but if you time it right, some buses will get you there in just 5 h .

On Tue, Sep 29 the slowest buses will take 5 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

  • AlsaNormal
    5:30 PM5h30
    Santander, Estación de Autobuses
    11:00 PMMadrid, Intercambiador de Avenida de América
    €361One-way
    0 transfers
  • AlsaNormal · Normal
    4:00 PM6h45
    Santander, Estación de Autobuses
    10:45 PMMadrid, Calle de la Princesa / Paseo de Moret (Moncloa)
    €371One-way
    1 transfer
  • AlsaNormal
    12:00 PM5h30
    Santander, Estación de Autobuses
    5:30 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)
    €411One-way
    0 transfers
  • AlsaNormal
    8:00 AM5h40
    Santander, Estación de Autobuses
    1:40 PMMadrid, Terminal de autobuses T4 (Aeropuerto de Madrid)
    €411One-way
    0 transfers
  • AlsaNormal
    12:00 PM5h45
    Santander, Estación de Autobuses
    5:45 PMMadrid, Intercambiador de Avenida de América
    €411One-way
    0 transfers

Live departures

Santander to Madrid bus times

The table below shows live departures for Santander to Madrid buses for today, Monday, September 28. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
FlixBusFlixBus · FlixBus9:25 AM Santander, Estación de Autobuses
21h45
7:10 AM Madrid, Estación Sur de Autobuses1 transfer
AlsaNormal10:30 AM Santander, Estación de Autobuses
6h15
4:45 PM Madrid, Intercambiador de Avenida de América0 transfersDirect
AlsaNormal12:00 PM Santander, Estación de Autobuses
5h30
5:30 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)0 transfersDirect
AlsaNormal12:00 PM Santander, Estación de Autobuses
5h45
5:45 PM Madrid, Intercambiador de Avenida de América0 transfersDirect
AlsaNormal5:30 PM Santander, Estación de Autobuses
5h30
11:00 PM Madrid, Intercambiador de Avenida de América0 transfersDirect
FlixBusFlixBus · FlixBus6:50 PM Santander, Estación de Autobuses
18h30
1:20 PM Madrid, Estación Sur de Autobuses1 transfer
Tuesday, September 29
AlsaSupra Economy12:45 AM Santander, Estación de Autobuses
5h45
6:30 AM Madrid, Intercambiador de Avenida de América0 transfersDirect
AlsaSupra Economy12:45 AM Santander, Estación de Autobuses
5h30
6:15 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)0 transfersDirect
AlsaNormal8:00 AM Santander, Estación de Autobuses
5h40
1:40 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)0 transfersDirect
AlsaNormal8:00 AM Santander, Estación de Autobuses
5h50
1:50 PM Madrid, Intercambiador de Avenida de América0 transfersDirect

Find all the dates and times for this journey

Compare prices and tickets Santander to Madrid by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Santander to Madrid buses with Omio?

Alsa as well as Alsa Supra or FlixBus offer buses services from Santander to Madrid.
Omio is an official ticket reseller for all your travel options from Santander to Madrid.

Why book with Omio vs Alsa?

  • Compare with other providers: On Omio, you can not only buy tickets for Alsa, but also compare tickets for the likes of Alsa Supra or FlixBus to find the best option for your trip from Santander to Madrid.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare Alsa with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Santander to Madrid.

Why book with Omio over Checkmybus, Rome2rio or Busbud?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Alsa Supra or FlixBus to find the best option for your trip from Santander to Madrid.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Santander to Madrid.

Journey information

Overview: Bus from Santander to Madrid

SpainSpain
SpainSpain
Icon of bus

Buses from Santander to Madrid run on average 13 times per day, taking around 7h 6m. Cheap bus tickets for this journey start at €32 but you can travel from only €7 by train.

There are 11 buses per day. The earliest bus runs at 00:30, the last at 23:45. The fastest bus covers the 339 km distance in 4h 15m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €7
Distance
339 km
Average bus duration
7h 6m
Cheapest ticket price
€32
Buses per day
13
Direct buses
11
Fastest bus
4h 15m
First bus
12:30 AM
Last bus
11:45 PM
Cheapest Month
Feb
Cheapest Day
Sat
High Season
Jul - Sep
Low Season
Jan - Mar
Busiest Day
Fri
Least Busy Day
Sun
Best time to book
91 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €7

Bus providers: Alsa, FlixBus, Alsa Supra from Santander to MadridYou can travel by bus between Santander to Madrid with Alsa, FlixBus, Alsa Supra for as low as €7. When you search for schedules and tickets, Omio will show you the best journey

Alsa

About
Alsa is the main provider of bus travel in Spain and a subsidiary of the UK’s National Express. It operates an extensive network of regional, national, and international routes, transporting more than 300 million passengers annually. Alsa’s modern fleet offers varying levels of comfort and amenities. The standard Alsa Normal buses include free Wi-Fi, onboard bathrooms, footrests, and entertainment. For a more premium experience, Alsa Supra, Alsa Eurobus, and Alsa Premium services provide enhanced comfort and luxury features.
Luggage & cancellation policy
Average Alsa Duration
4h 15m
Cheapest Alsa Price
€32
Alsa frequency
13 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 25kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 48 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating.
Bikes
Bikes are allowed for an additional fee; must be packed.
Pets
Small pets allowed in carriers; larger pets must travel in the hold.

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
15h 15m
Cheapest FlixBus Price
€37
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Alsa Supra

About
Alsa Supra is a premium service offered by Alsa, a leading Spanish bus company. It provides a high level of comfort and amenities for travelers, aiming to make each journey a unique experience. Key features of Alsa Supra buses include reclining leather seats with footrests, individual seating rows, high-speed Wi-Fi, USB chargers, and an \Ociobus\" on-board entertainment system with films, documentaries, and music. Passengers can also enjoy daily newspapers and a food and drink service, with a special menu available in the Premium class. Alsa Supra also offers services for people with reduced mobility, including reserved seating and wheelchair spaces. These services are available on various national and international routes."
Luggage & cancellation policy
Average Alsa Supra Duration
5h 0m
Cheapest Alsa Supra Price
€42
Alsa Supra frequency
4 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 25kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 48 hours before departure for a partial refund. Within 48 hours, a fee applies.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible restrooms.
Bikes
Bikes are allowed; prior reservation required.
Pets
Small pets allowed in carriers; guide dogs travel for free.

FAQs: Bus from Santander to Madrid

Find answers to the most common questions about traveling from Santander to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

FAQs
Cheap coach tickets from Santander to Madrid can start from as little as €32 when you book in advance. The average coach ticket price for Santander to Madrid is €48; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by coach from Santander to Madrid is 4h 15m to travel the 339 km long trip. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest coach from Santander to Madrid leaves at 12:30 AM. Plan your trip with the Journey Planner from Omio.
The latest coach from Santander to Madrid leaves at 11:45 PM.
Yes, there are 11 direct coaches a day from Santander to Madrid with Alsa, Alsa Supra. Schedules can vary on holidays or weekends with fewer direct coaches.
When taking a coach from Santander to Madrid, you can count on Alsa, Alsa Supra, FlixBus for the best way to get you to Madrid. You can also check all possible coach companies who offer a service between Santander and Madrid and compare the amenities they offer before buying a coach ticket.
When departing from Santander , you have various coach station options to start your trip from including Santander, Estación de Autobuses . When arriving in Madrid , you can end your trip in coach stations like Madrid, Intercambiador de Avenida de América, Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid), Madrid, Estación Sur de Autobuses, Madrid, Calle de la Princesa / Paseo de Moret (Moncloa) .Passengers board the coach most frequently from Santander, Estación de Autobuses, which is located around away from the city centre, and they get off the coach at Madrid, Intercambiador de Avenida de América, located 3 away from the city centre.
It's helpful to compare your options as there are 3 ways to travel between Santander and Madrid including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the coach from Santander to Madrid:
  • Alsa
    • Assistance
    • Priority boarding
    • Accessible seating.
  • Alsa Supra
    • Assistance
    • Priority boarding
    • Accessible restrooms.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
Yes, there are bathrooms on board the coach from Santander to Madrid for coach company Alsa, Alsa Supra, FlixBus.
Whether you can cancel your coach ticket from Santander to Madrid depends on the coach companies:
  • Alsa
    • You can cancel your ticket up to 48 hours before departure for a partial refund. Changes allowed for a fee.
  • Alsa Supra
    • You can cancel your ticket up to 48 hours before departure for a partial refund. Within 48 hours, a fee applies.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the coach with coach company Alsa, Alsa Supra, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the coach from Santander to Madrid.
Yes, the following luggage options are included when booking a coach ticket from Santander to Madrid:
  • Alsa
    • One carry-on bag up to 10kg and one checked bag up to 25kg.
  • Alsa Supra
    • One carry-on bag up to 10kg and one checked bag up to 25kg.
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a coach ticket from Santander to Madrid:
  • Alsa
    • Additional luggage can be purchased for a fee.
  • Alsa Supra
    • Additional luggage can be purchased for a fee.
  • FlixBus
    • Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the coach from Santander to Madrid. The following conditions apply:
  • Alsa
    • Small pets allowed in carriers
    • larger pets must travel in the hold.
  • Alsa Supra
    • Small pets allowed in carriers
    • guide dogs travel for free.
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
You can reserve your seat on the coach from Santander to Madrid with the following coach company: Alsa, Alsa Supra, FlixBus
Yes, there are USB plugs on board the coach from Santander to Madrid with the following coach company: Alsa, Alsa Supra, FlixBus.
Yes, there is Wifi on board the coach from Santander to Madrid with the following coach company: Alsa, Alsa Supra, FlixBus.

popular bus stations

Popular bus stations from Santander to Madrid

Most Santander to Madrid buses use the Santander, Estación de Autobuses to Madrid, Avenida de América station pair, with some services arriving at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid). Use this guide to compare Santander and Madrid bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.

Departure bus stations in Santander
Arrival bus stations in Madrid
Santander, Estación de AutobusesSantander Bus Station, Calle Navas de Tolosa 2, 39002

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