The cheapest and fastest buses from Santander to Madrid
Cheapest price
€24
Average price
€42
Fastest journey
4 h 10 m
Average duration
4 h 32 m
Buses per day
18
Distance
339 km
The best way to find a cheap bus ticket from Santander to Madrid is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Santander to Madrid will cost around €42 if you buy it on the day, but the cheapest tickets can be found for only €24.
Of the 18 buses that leave Santander for Madrid on Mon, Nov 17, 15 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Nov 17 the direct buses cover the 339 km distance in an average of 4 h 32 m but if you time it right, some buses will get you there in just 4 h 10 m .
On Mon, Nov 17 the slowest buses will take 5 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.









Supra EconomyTravel Information
Compare train, bus, and flight for Santander to Madrid
Omio recommends booking the train as it is the most popular option from Santander to Madrid among Omio's users. If you are prioritising price take the train with prices starting from €25. For those with little time consider booking a flight which can get you there in 1h 32m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a train costs an average of €25, and a flight costs an average of €60.
Distance: 339 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€72 Average price | €53 Average price Cheapest | €290 Average price |
8h 36m Average total duration 8h 6m Onboard + 30m Additional time* | 4h 55m Average total duration 4h 25m Onboard + 30m Additional time* | 4h 32m Average total duration Fastest 1h 32m Onboard + 3h 0m Additional time* |
0.3 - 0.8kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 1.0 - 2.0kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Santander to Madrid bus times
The table below shows live departures for Santander to Madrid buses for today, Sunday, November 16. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Normal | 7:00 AM Santander, Estación de Autobuses | 5h50 | 12:50 PM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
Normal | 7:00 AM Santander, Estación de Autobuses | 5h40 | 12:40 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 0 transfersDirect | |
FlixBus · FlixBus | 8:25 AM Santander, Estación de Autobuses | 21h45 | 6:10 AM Madrid, Estación Sur de Autobuses | 1 transfer | |
Normal · Normal | 3:00 PM Santander, Estación de Autobuses | 6h45 | 9:45 PM Madrid, Calle de la Princesa / Paseo de Moret (Moncloa) | 1 transfer | |
Normal | 4:30 PM Santander, Estación de Autobuses | 5h30 | 10:00 PM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
FlixBus · FlixBus | 5:50 PM Santander, Estación de Autobuses | 18h30 | 12:20 PM Madrid, Estación Sur de Autobuses | 1 transfer | |
Supra Economy | 11:45 PM Santander, Estación de Autobuses | 5h30 | 5:15 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 0 transfersDirect | |
Supra Economy | 11:45 PM Santander, Estación de Autobuses | 5h45 | 5:30 AM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
| Monday, November 17 | |||||
Normal | 12:00 AM Santander, Estación de Autobuses | 5h15 | 5:15 AM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 0 transfersDirect | |
Normal | 12:00 AM Santander, Estación de Autobuses | 5h30 | 5:30 AM Madrid, Intercambiador de Avenida de América | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Santander to Madrid by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 16
Nov 17
Nov 18
Nov 19
Nov 20
Nov 21
Nov 22
Nov 23
Nov 24
Nov 25
Nov 26
Nov 27
Nov 28
Nov 29
Nov 30
Dec 01
Dec 02
Dec 03
Dec 04
Dec 05
Dec 06
Journey information
Overview: Bus from Santander to Madrid
Buses from Santander to Madrid run on average 15 times per day, taking around 8h 6m. Cheap bus tickets for this journey start at €32 but you can travel from only €25 by train.
There are 12 buses per day. The earliest bus runs at 00:10, the last at 23:45. The fastest bus covers the 339 km distance in 5h 15m.
Distance 339 km |
Average bus duration 8h 6m |
Cheapest ticket price €32 |
Buses per day 15 |
Direct buses 12 |
Fastest bus 5h 15m |
First bus 00:10 |
Last bus 23:45 |
Bus providers: Alsa, Alsa Supra, BlaBlaCar, FlixBus from Santander to MadridYou can travel by bus between Santander to Madrid with Alsa, Alsa Supra, BlaBlaCar, FlixBus for as low as €25. When you search for schedules and tickets, Omio will show you the best journey
Alsa
Alsa Supra
FlixBus
BlaBlaCar
FAQs: Bus from Santander to Madrid
Find answers to the most common questions about traveling from Santander to Madrid by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Madrid, this guide helps you travel smarter and with confidence.

Passengers board the coach most frequently from Santander, Estación de Autobuses, which is located around 1.1 miles (1.8 km) away from the city centre, and they get off the coach at Madrid, Avenida de América, located 3.2 miles (5.2 km) away from the city centre.
To find the cheapest bus tickets for your trip from Santander to Madrid, follow these tips:
Start your search now and compare ticket prices to find the best deal!
popular bus stations
Popular bus stations from Santander to Madrid
- 06:00-23:00
- Free Wi-Fi
- Cafetería de la estación (in the station)
- Restaurante El Rincón (0.5 km)
- La Vaca Argentina (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 200, 114, 115, 122 Metro: 4, 6, 7, 9
- 06:00-23:00
- Free Wi-Fi
- Cafetería de la estación (in the station)
- Restaurante El Brillante (0.5 km)
- La Taberna de Domínguez (0.7 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 8, 102, 148 Metro: L6 Train: C1, C5
- 06:00-23:00
- Free Wi-Fi
- Available near the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 1, 2, 44, 82, 132, C1, C2 Metro: 3, 6
Most popular bus connections from Santander
More options for your journey from Santander to Madrid
Here are some other resources that might have the information you need



