The cheapest and fastest buses from Assisi to Milan
Cheapest price
€44
Average price
€51
Fastest journey
6 h 50 m
Average duration
7 h 25 m
Buses per day
2
Distance
381 km
The best way to find a cheap bus ticket from Assisi to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Assisi to Milan will cost around €51 if you buy it on the day, but the cheapest tickets can be found for only €44.
Of the 2 buses that leave Assisi for Milan on Sun, Mar 08, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 08 the direct buses cover the 381 km distance in an average of 7 h 25 m but if you time it right, some buses will get you there in just 6 h 50 m .
On Sun, Mar 08 the slowest buses will take 8 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare bus, train, and flight for Assisi to Milan
Omio recommends booking the train as it is the most popular option from Assisi to Milan among Omio's users. If you are prioritising price take the bus with prices starting from €19. For those with little time consider booking a flight which can get you there in 2h 32m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of €19, and a flight costs an average of €47.
Distance: 381 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€38 Average price Cheapest | €42 Average price | €81 Average price |
5h 48m Average total duration 5h 18m Onboard + 30m Additional time* | 5h 49m Average total duration 5h 19m Onboard + 30m Additional time* | 5h 32m Average total duration Fastest 2h 32m Onboard + 3h 0m Additional time* |
0.4 - 1.0kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 1.1 - 2.3kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Assisi to Milan bus times
The table below shows live departures for Assisi to Milan buses for today, Saturday, March 7. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 3:35 PM Assisi, Pizza San Pietro | 7h00 | 10:35 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus | 3:35 PM Assisi, Pizza San Pietro | 6h25 | 10:00 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 3:45 PM Assisi, Santa Maria degli Angeli Stazione | 6h15 | 10:00 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 0 transfersDirect | |
FlixBus | 3:45 PM Assisi, Santa Maria degli Angeli Stazione | 6h50 | 10:35 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
| Sunday, March 8 | |||||
![]() | 6:20 AM Assisi | 8h00 | 2:20 PM Milan | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Assisi to Milan by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 08
Mar 09
Mar 10
Mar 11
Mar 12
Mar 13
Mar 14
Mar 15
Mar 16
Mar 17
Mar 18
Mar 19
Mar 20
Mar 21
Mar 22
Mar 23
Mar 24
Mar 25
Mar 26
Mar 27
Mar 28
Why should you book Assisi to Milan buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Assisi to Milan.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Assisi to Milan.
Journey information
Overview: Bus from Assisi to Milan
Buses from Assisi to Milan run on average 7 times per day, taking around 5h 18m. Cheap bus tickets for this journey start at €19 but you can travel from only €18 by train.
There are 4 buses per day. The earliest bus runs at 00:23, the last at 23:45. The fastest bus covers the 381 km distance in 5h 1m.
Distance 381 km |
Average bus duration 5h 18m |
Cheapest ticket price €19 |
Buses per day 7 |
Direct buses 4 |
Fastest bus 5h 1m |
First bus 00:23 |
Last bus 23:45 |
Bus providers: FlixBus, BlaBlaCar from Assisi to MilanYou can travel by bus between Assisi to Milan with FlixBus, BlaBlaCar for as low as €18. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar
FAQs: Bus from Assisi to Milan
Find answers to the most common questions about traveling from Assisi to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Assisi to Milan
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M1 Bus: 68, 78, 80
- 06:00-22:00
- Free Wi-Fi
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Bus: 121, 132 Metro: M3
More options for your journey from Assisi to Milan
Here are some other resources that might have the information you need


