The cheapest and fastest buses from Prague to Milan
Cheapest price
€65
Average price
€93
Fastest journey
12 h 35 m
Average duration
13 h
Buses per day
36
Distance
646 km
The best way to find a cheap bus ticket from Prague to Milan is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Milan will cost around €93 if you buy it on the day, but the cheapest tickets can be found for only €65.
Of the 36 buses that leave Prague for Milan on Sun, Mar 01, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Mar 01 the direct buses cover the 646 km distance in an average of 13 h but if you time it right, some buses will get you there in just 12 h 35 m .
On Sun, Mar 01 the slowest buses will take 13 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
FlixBus
FlixBus
30507 · 4733
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
FlixBus · FlixBus
FlixBus
FlixBusTravel Information
Compare bus, flight, and train for Prague to Milan
Omio recommends booking the flight as it is the most popular option from Prague to Milan among Omio's users. If you are prioritising price take the bus with prices starting from €39. For those with little time consider booking a flight which can get you there in 2h 36m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.6 - 1.6kg. The ticket price range depends on the travel mode: a bus costs an average of €39, and a flight costs an average of €28.
Distance: 646 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€68 Average price Cheapest | €125 Average price | €120 Average price |
16h 25m Average total duration 15h 55m Onboard + 30m Additional time* | 5h 36m Average total duration Fastest 2h 36m Onboard + 3h 0m Additional time* | 19h 38m Average total duration 19h 8m Onboard + 30m Additional time* |
0.6 - 1.6kg CO2 emissions Lowest | 1.9 - 3.9kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Prague to Milan bus times
The table below shows live departures for Prague to Milan buses for today, Saturday, February 28. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 7:30 AM Praha, Roztyly | 18h20 | 1:50 AM Milano, Autostazione Lampugnano | 2 transfers | |
FlixBus · FlixBus | 7:55 AM Praha, Zličín | 15h10 | 11:05 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 8:00 AM Prague, Central Train Station | 15h05 | 11:05 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 8:40 AM Praha, Na Knížecí | 14h25 | 11:05 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus | 9:20 AM Praha, ÚAN Florenc | 13h45 | 11:05 PM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 11:50 AM Praha, M. Horákové (Hradčanská) | 21h15 | 9:05 AM Milano, Milan Linate Airport | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:50 AM Praha, M. Horákové (Hradčanská) | 17h40 | 5:30 AM Milano, Autostazione Lampugnano | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:50 AM Praha, ÚAN Florenc | 18h35 | 6:25 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:55 AM Praha, Zličín | 17h35 | 5:30 AM Milano, Autostazione Lampugnano | 2 transfers | |
FlixBus · FlixBus · FlixBus | 12:05 PM Prague, Central Train Station | 18h20 | 6:25 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
FlixBus · FlixBus | 12:05 PM Prague, Central Train Station | 13h45 | 1:50 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 1:30 PM Praha, Černý Most | 19h35 | 9:05 AM Milano, Milan Linate Airport | 2 transfers | |
FlixBus · FlixBus | 1:30 PM Praha, Černý Most | 16h00 | 5:30 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 3:15 PM Praha, ÚAN Florenc | 14h15 | 5:30 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 3:15 PM Prague, Central Train Station | 14h15 | 5:30 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 4:10 PM Praha, Roztyly | 16h00 | 8:10 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 4:15 PM Praha, ÚAN Florenc | 17h05 | 9:20 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:15 PM Praha, ÚAN Florenc | 16h50 | 9:05 AM Milano, Milan Linate Airport | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:30 PM Prague, Central Train Station | 16h35 | 9:05 AM Milano, Milan Linate Airport | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:30 PM Prague, Central Train Station | 16h50 | 9:20 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:45 PM Praha, Na Knížecí | 15h25 | 8:10 AM Milano, Autostazione Lampugnano | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:45 PM Praha, Na Knížecí | 18h10 | 10:55 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
FlixBus · FlixBus | 6:25 PM Praha, Zličín | 13h45 | 8:10 AM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 7:10 PM Praha, ÚAN Florenc | 15h45 | 10:55 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
FlixBus | 7:10 PM Praha, ÚAN Florenc | 13h00 | 8:10 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 7:20 PM Prague, Central Train Station | 15h35 | 10:55 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
FlixBus | 7:20 PM Prague, Central Train Station | 12h50 | 8:10 AM Milano, Autostazione Lampugnano | 0 transfersDirect | |
FlixBus · FlixBus | 8:25 PM Praha, ÚAN Florenc | 17h10 | 1:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 1 transfer | |
FlixBus · FlixBus | 9:25 PM Praha, M. Horákové (Hradčanská) | 17h05 | 2:30 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:35 PM Praha, ÚAN Florenc | 17h35 | 4:10 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
FlixBus · FlixBus | 10:35 PM Praha, ÚAN Florenc | 15h10 | 1:45 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:45 PM Praha, ÚAN Florenc | 21h10 | 7:55 PM Milano, Milan Linate Airport | 2 transfers | |
FlixBus · FlixBus | 10:45 PM Praha, ÚAN Florenc | 18h05 | 4:50 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus | 10:50 PM Prague, Central Train Station | 14h55 | 1:45 PM Milano, Autostazione Lampugnano | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:50 PM Prague, Central Train Station | 21h05 | 7:55 PM Milano, Milan Linate Airport | 2 transfers | |
FlixBus · FlixBus · FlixBus | 10:50 PM Prague, Central Train Station | 17h20 | 4:10 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 2 transfers | |
| Sunday, March 1 | |||||
FlixBus · FlixBus · FlixBus | 1:30 AM Prague, Central Train Station | 18h25 | 7:55 PM Milano, Milan Linate Airport | 2 transfers | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Milan by bus, flight, or train
Compare bus, flight, and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 28
Mar 01
Mar 02
Mar 03
Mar 04
Mar 05
Mar 06
Mar 07
Mar 08
Mar 09
Mar 10
Mar 11
Mar 12
Mar 13
Mar 14
Mar 15
Mar 16
Mar 17
Mar 18
Mar 19
Mar 20
Why should you book Prague to Milan buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Infobus, BlaBlaCar Bus or Musil Tour to find the best option for your trip from Prague to Milan.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, flight and train to ensure you get the best deal for traveling from Prague to Milan.
Why book with Omio over Wanderu, Trainline or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Infobus, BlaBlaCar Bus or Musil Tour to find the best option for your trip from Prague to Milan.
- Multiple modes of transport: Omio allows you to compare travel options including bus, flight and train to find the ideal travel option from Prague to Milan.
Journey information
Overview: Bus from Prague to Milan
Buses from Prague to Milan run on average 39 times per day, taking around 15h 55m. Cheap bus tickets for this journey start at €39 but you can travel from only €23 by train.
There are 2 buses per day. The earliest bus runs at 01:00, the last at 23:55. The fastest bus covers the 646 km distance in 12h 50m.
Distance 646 km |
Average bus duration 15h 55m |
Cheapest ticket price €39 |
Buses per day 39 |
Direct buses 2 |
Fastest bus 12h 50m |
First bus 01:00 |
Last bus 23:55 |
Bus providers: FlixBus, Infobus, BlaBlaCar Bus, Musil Tour from Prague to MilanYou can travel by bus between Prague to Milan with FlixBus, Infobus, BlaBlaCar Bus, Musil Tour for as low as €23. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
BlaBlaCar Bus
Musil Tour
FAQs: Bus from Prague to Milan
Find answers to the most common questions about traveling from Prague to Milan by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- 10€ per additional bag.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Prague to Milan
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M1 Bus: 68, 78, 80
- 06:00-22:00
- Free Wi-Fi
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Bus: 121, 132 Metro: M3
Most popular bus connections from Prague
More options for your journey from Prague to Milan
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