The cheapest and fastest buses from Florence Santa Maria Novella to Naples Centrale
Cheapest price
€45
Average price
€69
Fastest journey
4 h 20 m
Average duration
5 h 5 m
Buses per day
10
Distance
409 km
The best way to find a cheap bus ticket from Florence Santa Maria Novella to Naples Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence Santa Maria Novella to Naples Centrale will cost around €69 if you buy it on the day, but the cheapest tickets can be found for only €45.
Of the 10 buses that leave Florence Santa Maria Novella for Naples Centrale on Sun, Dec 21, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Dec 21 the direct buses cover the 409 km distance in an average of 5 h 5 m but if you time it right, some buses will get you there in just 4 h 20 m .
On Sun, Dec 21 the slowest buses will take 5 h 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








FlixBus
FlixBusTravel Information
Compare train, bus, and flight for Florence Santa Maria Novella to Naples Centrale
Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Naples Centrale among Omio's users. If you are prioritising price take the bus with prices starting from €5. For those with little time consider booking a flight which can get you there in 1h 44m. The ticket price range depends on the travel mode: a bus costs an average of €5, and a flight costs an average of €145.
Distance: 409 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€26 Average price Cheapest | €64 Average price | €300 Average price |
6h 16m Average total duration 5h 46m Onboard + 30m Additional time* | 5h 11m Average total duration 4h 41m Onboard + 30m Additional time* | 4h 44m Average total duration Fastest 1h 44m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Live departures
Florence Santa Maria Novella to Naples Centrale bus times
The table below shows live departures for Florence Santa Maria Novella to Naples Centrale buses for today, Saturday, December 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 2:45 PM Florence Santa Maria Novella | 6h25 | 9:10 PM Naples Centrale | 0 transfersDirect | |
![]() | 3:55 PM Florence Santa Maria Novella | 6h00 | 9:55 PM Naples Centrale | 0 transfersDirect | |
![]() | 6:05 PM Florence Santa Maria Novella | 6h30 | 12:35 AM Naples Centrale | 0 transfersDirect | |
| Sunday, December 21 | |||||
FlixBus | 12:05 AM Firenze, Piazzale Montelungo | 5h55 | 6:00 AM Napoli, Napoli Centrale | 0 transfersDirect | |
FlixBus | 12:35 AM Firenze, Piazzale Montelungo | 5h40 | 6:15 AM Napoli, Napoli Centrale | 0 transfersDirect | |
FlixBus · FlixBus | 1:45 AM Firenze, Piazzale Montelungo | 7h05 | 8:50 AM Napoli, Napoli Centrale | 1 transfer | |
FlixBus | 3:05 AM Firenze, Piazzale Montelungo | 6h35 | 9:40 AM Napoli, Napoli Centrale | 0 transfersDirect | |
FlixBus · FlixBus | 4:40 AM Firenze, Piazzale Montelungo | 7h45 | 12:25 PM Napoli, Napoli Centrale | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence Santa Maria Novella to Naples Centrale by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Journey information
Overview: Bus from Florence Santa Maria Novella to Naples Centrale
Buses from Florence Santa Maria Novella to Naples Centrale run on average 6 times per day, taking around 5h 46m. Cheap bus tickets for this journey start at €5 if you book in advance.
There are 4 buses per day. The earliest bus runs at 00:35, the last at 21:40. The fastest bus covers the 409 km distance in 5h 40m.
Distance 409 km |
Average bus duration 5h 46m |
Cheapest ticket price €5 |
Buses per day 6 |
Direct buses 4 |
Fastest bus 5h 40m |
First bus 00:35 |
Last bus 21:40 |
Bus providers: Itabus, FlixBus, BlaBlaCar, Calanda Viaggi, Marino Autolinee, Infobus, BlaBlaCar Bus from Florence Santa Maria Novella to Naples CentraleYou can travel by bus between Florence Santa Maria Novella to Naples Centrale with Itabus, FlixBus, BlaBlaCar, Calanda Viaggi, Marino Autolinee, Infobus, BlaBlaCar Bus for as low as €5. When you search for schedules and tickets, Omio will show you the best journey
Itabus
FlixBus
Marino Autolinee
Infobus
BlaBlaCar Bus
Calanda Viaggi
BlaBlaCar
FAQs: Bus from Florence Santa Maria Novella to Naples Centrale
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Naples Centrale by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Naples Centrale, this guide helps you travel smarter and with confidence.

To find the cheapest bus tickets for your trip from Florence Santa Maria Novella to Naples Centrale, follow these tips:
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