The cheapest and fastest buses from Florence Santa Maria Novella to Siena
Cheapest price
€4
Average price
€10
Fastest journey
50 m
Average duration
52 m
Buses per day
19
Distance
51 km
The best way to find a cheap bus ticket from Florence Santa Maria Novella to Siena is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Florence Santa Maria Novella to Siena will cost around €10 if you buy it on the day, but the cheapest tickets can be found for only €4.
Of the 19 buses that leave Florence Santa Maria Novella for Siena on Thu, Mar 05, 19 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Mar 05 the direct buses cover the 51 km distance in an average of 52 m but if you time it right, some buses will get you there in just 50 m .
On Thu, Mar 05 the slowest buses will take 55 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.






FlixBus
FlixBus
2125
2495Travel Information
Compare train and bus for Florence Santa Maria Novella to Siena
Omio recommends booking the train as it is the most popular option from Florence Santa Maria Novella to Siena among Omio's users. If you are prioritising price take the bus with prices starting from €5. For those with little time consider booking a bus which can get you there in 1h 9m. The ticket price range depends on the travel mode: a bus costs an average of €5, and a train costs an average of €10.
Distance: 51 km
Compare bus with
| Bus | Most popular Train |
|---|---|
€8 Average price Cheapest | €10 Average price |
1h 39m Average total duration Fastest 1h 9m Onboard + 30m Additional time* | 1h 43m Average total duration 1h 13m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Live departures
Florence Santa Maria Novella to Siena bus times
The table below shows live departures for Florence Santa Maria Novella to Siena buses for tomorrow, Thursday, March 5. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
2495 | 3:15 AM Scandicci, Villa Costanza (Florence) | 0h55 | 4:10 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 3:40 AM Scandicci, Villa Costanza (Florence) | 0h50 | 4:30 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 6:45 AM Scandicci, Villa Costanza (Florence) | 0h55 | 7:40 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 8:00 AM Scandicci, Villa Costanza (Florence) | 0h55 | 8:55 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
207 | 9:05 AM Scandicci, Villa Costanza (Florence) | 1h00 | 10:05 AM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
2723 | 11:45 AM Scandicci, Villa Costanza (Florence) | 0h55 | 12:40 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 12:30 PM Scandicci, Villa Costanza (Florence) | 0h50 | 1:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 12:45 PM Scandicci, Villa Costanza (Florence) | 0h55 | 1:40 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
2125 | 2:25 PM Scandicci, Villa Costanza (Florence) | 0h55 | 3:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 5:00 PM Scandicci, Villa Costanza (Florence) | 0h55 | 5:55 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 5:10 PM Scandicci, Villa Costanza (Florence) | 0h55 | 6:05 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 6:05 PM Scandicci, Villa Costanza (Florence) | 0h55 | 7:00 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 7:20 PM Scandicci, Villa Costanza (Florence) | 0h55 | 8:15 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
FlixBus | 8:25 PM Scandicci, Villa Costanza (Florence) | 0h55 | 9:20 PM Siena, Stazione FS (Piazzale Carlo Rosselli) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Florence Santa Maria Novella to Siena by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Mar 05
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Mar 13
Mar 14
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Mar 16
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Mar 18
Mar 19
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Mar 21
Mar 22
Mar 23
Mar 24
Mar 25
Why should you book Florence Santa Maria Novella to Siena buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Marino Autolinee, Itabus, Curcio Viaggi or Autolinee Toscane - Urbano Area Metropolitana Fiorentina to find the best option for your trip from Florence Santa Maria Novella to Siena.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Florence Santa Maria Novella to Siena.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Marino Autolinee, Itabus, Curcio Viaggi or Autolinee Toscane - Urbano Area Metropolitana Fiorentina to find the best option for your trip from Florence Santa Maria Novella to Siena.
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Florence Santa Maria Novella to Siena.
Journey information
Overview: Bus from Florence Santa Maria Novella to Siena
Buses from Florence Santa Maria Novella to Siena run on average 16 times per day, taking around 1h 9m. Cheap bus tickets for this journey start at €5 if you book in advance.
There are 13 buses per day. The earliest bus runs at 02:00, the last at 20:25. The fastest bus covers the 51 km distance in 50m.
Distance 51 km |
Average bus duration 1h 9m |
Cheapest ticket price €5 |
Buses per day 16 |
Direct buses 13 |
Fastest bus 50m |
First bus 02:00 |
Last bus 20:25 |
Bus providers: FlixBus, Marino Autolinee, BlaBlaCar, Itabus, Curcio Viaggi, Autolinee Toscane - Urbano Area Metropolitana Fiorentina from Florence Santa Maria Novella to SienaYou can travel by bus between Florence Santa Maria Novella to Siena with FlixBus, Marino Autolinee, BlaBlaCar, Itabus, Curcio Viaggi, Autolinee Toscane - Urbano Area Metropolitana Fiorentina for as low as €5. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Marino Autolinee
Itabus
BlaBlaCar
Curcio Viaggi
Autolinee Toscane - Urbano Area Metropolitana Fiorentina
FAQs: Bus from Florence Santa Maria Novella to Siena
Find answers to the most common questions about traveling from Florence Santa Maria Novella to Siena by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Siena, this guide helps you travel smarter and with confidence.

- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Florence Santa Maria Novella to Siena
More options for your journey from Florence Santa Maria Novella to Siena
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