Florence Santa Maria Novella to Milan Centrale bus with FlixBus

Fri, Sep 18
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The cheapest and fastest buses from Florence Santa Maria Novella to Milan Centrale

Showing times, prices and bookable tickets for Sep 18

Cheapest price on Sep 18

€56

Average ticket price on Sep 18

€56

Fastest journey on Sep 18

3 h 38 m

Average journey duration on Sep 18

4 h 12 m

Buses on Sep 18

12

Distance

250 km

Cheap tickets

The best way to find a cheap bus ticket from Florence Santa Maria Novella to Milan Centrale is to book your journey as far in advance as possible and to avoid traveling at rush hour.

The average ticket from Florence Santa Maria Novella to Milan Centrale will cost around €56 if you buy it on the day, but the cheapest tickets can be found for only €56.

Fast buses

It's difficult to get from Florence Santa Maria Novella to Milan Centrale without transferring at least 2 times.

  • RegionaleRegionale 18492 · Autobus TTPER B0404+Italo9986
    12:37 PM5h38
    Florence Santa Maria Novella
    6:15 PMMilan Centrale
    561One-way
    2 transfers
  • RegionaleRegionale 18664 · Autobus TTPER B0400+Italo9982
    10:20 AM5h55
    Florence Santa Maria Novella
    4:15 PMMilan Centrale
    561One-way
    2 transfers
  • RegionaleRegionale 18664 · Autobus TTPER B0400+Italo9978
    10:20 AM3h55
    Florence Santa Maria Novella
    2:15 PMMilan Centrale
    561One-way
    2 transfers
  • RegionaleRegionale 18508 · Treno 17820 effettuato con bus FI680+Italo9978
    9:09 AM5h06
    Florence Santa Maria Novella
    2:15 PMMilan Centrale
    561One-way
    2 transfers
  • RegionaleRegionale 18490 · Autobus TTPER B0402+Italo9932
    11:38 AM4h42
    Florence Santa Maria Novella
    4:20 PMMilan Centrale
    561One-way
    2 transfers

Travel Information

Compare train, bus, and flight for Florence Santa Maria Novella to Milan Centrale

Omio recommends booking the flight as it is the most popular option from Florence Santa Maria Novella to Milan Centrale among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €20 For those with little time, consider booking a train, which has an average total journey time of 3h 12m. Average ticket prices depend on the travel mode: a bus costs an average of €20, while a flight costs an average of €322.

Distance: 250 km

Compare bus with

Bus
Most popular
Flight
Train
Driving

€20

Average price

Cheapest

€322

Average price

€32

Average price

€74

Average price

(fuel + tolls)

5h 8m

Average total duration

4h 38m

Onboard

+

30m

Additional time*

5h 6m

Average total duration

3h 6m

Onboard

+

2h 0m

Additional time*

3h 12m

Average total duration

Fastest

2h 42m

Onboard

+

30m

Additional time*

3h 20m

Average total duration

(door-to-door)

Direct Options

Direct Options

Direct Options

Direct Options

The cheapest way to travel from Florence Santa Maria Novella to Milan Centrale is a bus with an average price of €14.

This is compared to other travel options from Florence Santa Maria Novella to Milan Centrale:

A bus is €14 less than a train for this route with tickets for a train from Florence Santa Maria Novella to Milan Centrale costing on average €28.

A bus is €226 less than a flight for this route with tickets for a flight from Florence Santa Maria Novella to Milan Centrale costing on average €240.

The fastest way to travel from Florence Santa Maria Novella to Milan Centrale is by train with an average journey time of 3h 37m.

Other travel options to Milan Centrale take longer:

Bus takes on average 4h 10m.

Flight takes on average 4h 14m.

It's helpful to compare your options as there are 3 ways to travel between Florence Santa Maria Novella and Milan Centrale including taking a train, bus, and flight.

Live departures

Florence Santa Maria Novella to Milan Centrale bus times

The table below shows live departures for Florence Santa Maria Novella to Milan Centrale buses for today, Thursday, September 17. You can also manually refresh the results below to see updated bus journeys.

Last updated at
ProviderDepartsDurationArrivesTransfers
Tickets
RegionaleRegionale 18508 · Treno 17820 effettuato con bus FI680+Italo99769:09 AM Florence Santa Maria Novella
4h06
1:15 PM Milan Centrale2 transfers
RegionaleRegionale 18508 · Treno 17820 effettuato con bus FI680+Italo99249:09 AM Florence Santa Maria Novella
5h11
2:20 PM Milan Centrale2 transfers
RegionaleRegionale 18508 · Treno 17820 effettuato con bus FI680+Italo99789:09 AM Florence Santa Maria Novella
5h06
2:15 PM Milan Centrale2 transfers
RegionaleRegionale 18664 · Autobus TTPER B0400+Italo992810:20 AM Florence Santa Maria Novella
5h00
3:20 PM Milan Centrale2 transfers
RegionaleRegionale 18664 · Autobus TTPER B0400+Italo998210:20 AM Florence Santa Maria Novella
5h55
4:15 PM Milan Centrale2 transfers
RegionaleRegionale 18664 · Autobus TTPER B0400+Italo997810:20 AM Florence Santa Maria Novella
3h55
2:15 PM Milan Centrale2 transfers
RegionaleRegionale 18490 · Autobus TTPER B0402+Italo998211:38 AM Florence Santa Maria Novella
4h37
4:15 PM Milan Centrale2 transfers
RegionaleRegionale 18490 · Autobus TTPER B0402+Italo993211:38 AM Florence Santa Maria Novella
4h42
4:20 PM Milan Centrale2 transfers
RegionaleRegionale 18490 · Autobus TTPER B0402+Italo813411:38 AM Florence Santa Maria Novella
5h42
5:20 PM Milan Centrale2 transfers
RegionaleRegionale 18492 · Autobus TTPER B0404+Italo998612:37 PM Florence Santa Maria Novella
5h38
6:15 PM Milan Centrale2 transfers
RegionaleRegionale 18492 · Autobus TTPER B0404+Italo998212:37 PM Florence Santa Maria Novella
3h38
4:15 PM Milan Centrale2 transfers
RegionaleRegionale 18492 · Autobus TTPER B0404+Italo813412:37 PM Florence Santa Maria Novella
4h43
5:20 PM Milan Centrale2 transfers

This is the last bus of the day.

Find all the dates and times for this journey

Compare prices and tickets Florence Santa Maria Novella to Milan Centrale by train, bus, or flight

Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.

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Why should you book Florence Santa Maria Novella to Milan Centrale buses with Omio?

FlixBus as well as Itabus, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi and more offer buses services from Florence Santa Maria Novella to Milan Centrale.
Omio is an official ticket reseller for all your travel options from Florence Santa Maria Novella to Milan Centrale.

Why book with Omio vs FlixBus?

  • Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Itabus, BlaBlaCar Bus, Marino Autolinee or Calanda Viaggi to find the best option for your trip from Florence Santa Maria Novella to Milan Centrale.
  • Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
  • Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Florence Santa Maria Novella to Milan Centrale.

Why book with Omio over Wanderu, Trainline or Checkmybus?

  • Compare with other providers: On Omio, you can also compare tickets for the likes of Itabus, BlaBlaCar Bus, Marino Autolinee or Calanda Viaggi to find the best option for your trip from Florence Santa Maria Novella to Milan Centrale.
  • Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Florence Santa Maria Novella to Milan Centrale.

Journey information

Overview: Bus from Florence Santa Maria Novella to Milan Centrale

ItalyItaly
ItalyItaly
Icon of bus

Buses from Florence Santa Maria Novella to Milan Centrale run on average 31 times per day, taking around 4h 10m. Cheap bus tickets for this journey start at €8 if you book in advance.

There are 26 buses per day. The earliest bus runs at 00:15, the last at 23:50. The fastest bus covers the 250 km distance in 3h 15m.

Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance
250 km
Average bus duration
4h 10m
Cheapest ticket price
€8
Buses per day
31
Direct buses
26
Fastest bus
3h 15m
First bus
12:15 AM
Last bus
11:50 PM
Cheapest Month
Jun
Cheapest Day
Sat
High Season
Oct - Dec
Low Season
Jan - Mar
Busiest Day
Thu
Least Busy Day
Sat
Best time to book
7 days
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information

Bus providers: FlixBus, Itabus, BlaBlaCar, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi from Florence Santa Maria Novella to Milan CentraleYou can travel by bus between Florence Santa Maria Novella to Milan Centrale with FlixBus, Itabus, BlaBlaCar, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi for as low as €8. When you search for schedules and tickets, Omio will show you the best journey

FlixBus

About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average FlixBus Duration
3h 15m
Cheapest FlixBus Price
€9
FlixBus frequency
2 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.

Itabus

About
Itabus is a leading bus company in Italy, providing reliable and comfortable transportation services to its customers. Itabus operates a fleet of modern buses, ranging from luxury coaches to standard buses, all equipped with air conditioning, comfortable seating, and onboard entertainment.
Luggage & cancellation policy
Average Itabus Duration
4h 15m
Cheapest Itabus Price
€8
Itabus frequency
7 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
5€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Dedicated seating areas; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.

Marino Autolinee

About
MarinoBus is an Italian bus company with more than 200 destinations and 6,000 connections across Italy and Europe. Originally focused on Basilicata and Apulia, its network has expanded to cover the rest of Italy as well as Switzerland, France, Germany, and Luxembourg. All MarinoBus coaches are equipped with spacious reclining seats, air conditioning, onboard restrooms, WiFi, minibars, and color TVs. For your next trip, you can book the standard ticket, which includes one piece of hand luggage and up to two checked bags per passenger
Luggage & cancellation policy
Marino Autolinee frequency
2 a day
Luggage included
One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
10€ per additional bag up to 20 kg.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Accessible restrooms.
Bikes
Bikes are allowed.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.

BlaBlaCar Bus

About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average BlaBlaCar Bus Duration
4h 25m
Cheapest BlaBlaCar Bus Price
€8
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
Bikes
Bikes are allowed; additional fees may apply.

Calanda Viaggi

About
Calanda Viaggi is an Italian bus company that originated in Switzerland in 1989 as Calanda Reisen, founded to serve Italian communities traveling to and from their home country. Headquartered in Chiaravalle Centrale, Italy, Calanda Viaggi connects a significant portion of Italy, including regions like Calabria, Tuscany, and Lombardy, with various Swiss cities such as Zurich, Bern, and Basel. The company emphasizes affordability and a comfortable onboard experience, offering amenities like air conditioning, restrooms, and often Wi-Fi and movie screenings. Calanda Viaggi also provides bus and minibus rentals for various events and organized trips within Italy and Europe.
Luggage & cancellation policy
Calanda Viaggi frequency
3 a day
Luggage included
One checked bag and one small hand luggage item are generally included, but specific size and weight details are not explicitly stated and may vary.
Additional luggage
Additional luggage may be allowed, but details on fees and restrictions are not specified.
Cancellation Policy
The cancellation policy can vary by ticket class, individual trips, or promotions; passengers should check the policies during the booking process.
Pregnant on board
Calanda Viaggi does not impose restrictions on flying if you are pregnant, but it is advisable to check with your doctor if traveling after the eighth month.
Unaccompagned minor
Unaccompanied minors must have an authorization form signed by their parents.
Amenities on board the bus
Wifi
Toilets
USB plugs

BlaBlaCar

About
BlaBlaCar is a French online marketplace for carpooling, connecting drivers with empty seats and passengers traveling to the same destination to share costs. Founded in 2006, it operates in Europe and Latin America, boasting 26 million active members. The platform also includes BlaBlaCar Bus, an intercity bus service. BlaBlaCar's name comes from its rating system for drivers' chattiness: \Bla\" for quiet, \"BlaBla\" for talkative, and \"BlaBlaBla\" for very chatty. The company aims to be the leading marketplace for shared travel, offering affordable and sustainable solutions by combining carpooling with bus journeys."
Luggage & cancellation policy
BlaBlaCar frequency
4 a day

FAQs: Bus from Florence Santa Maria Novella to Milan Centrale

Find answers to the most common questions about traveling from Florence Santa Maria Novella to Milan Centrale by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Milan Centrale, this guide helps you travel smarter and with confidence.

FAQs
Cheap coach tickets from Florence Santa Maria Novella to Milan Centrale can start from as little as €8 when you book in advance. The average coach ticket price for Florence Santa Maria Novella to Milan Centrale is €14; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by coach from Florence Santa Maria Novella to Milan Centrale is 3h 15m to travel the 250 km long trip. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest coach from Florence Santa Maria Novella to Milan Centrale leaves at 12:15 AM. Plan your trip with the Journey Planner from Omio.
The latest coach from Florence Santa Maria Novella to Milan Centrale leaves at 11:50 PM.
Yes, there are 26 direct coaches a day from Florence Santa Maria Novella to Milan Centrale with FlixBus, Itabus, BlaBlaCar, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi. Schedules can vary on holidays or weekends with fewer direct coaches.
When taking a coach from Florence Santa Maria Novella to Milan Centrale, you can count on FlixBus, Itabus, BlaBlaCar, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi for the best way to get you to Milan Centrale. You can also check all possible coach companies who offer a service between Florence Santa Maria Novella and Milan Centrale and compare the amenities they offer before buying a coach ticket.
A trip to Milan Centrale from Florence Santa Maria Novella is worth doing but not as a day trip with a journey time of 3h 15m each way. Check with Omio app the best way to travel.
The cheapest month for a coach from Florence Santa Maria Novella to Milan Centrale is June.
It's helpful to compare your options as there are 3 ways to travel between Florence Santa Maria Novella and Milan Centrale including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the coach from Florence Santa Maria Novella to Milan Centrale:
  • BlaBlaCar Bus
    • Assistance
    • Priority boarding
    • Accessible seating options.
  • FlixBus
    • Assistance
    • Priority boarding
    • Wheelchair-accessible buses.
  • Itabus
    • Assistance
    • Dedicated seating areas
    • Accessible restrooms.
Yes, there are bathrooms on board the coach from Florence Santa Maria Novella to Milan Centrale for coach company FlixBus, Itabus, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi.
Whether you can cancel your coach ticket from Florence Santa Maria Novella to Milan Centrale depends on the coach companies:
  • BlaBlaCar Bus
    • You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
  • FlixBus
    • You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
  • Itabus
    • You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
Yes, bikes are allowed on board the coach with coach company FlixBus, Itabus, BlaBlaCar Bus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the coach from Florence Santa Maria Novella to Milan Centrale.
Yes, the following luggage options are included when booking a coach ticket from Florence Santa Maria Novella to Milan Centrale:
  • BlaBlaCar Bus
    • One carry-on bag up to 7kg and one checked bag up to 20kg.
  • FlixBus
    • One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
  • Itabus
    • One carry-on bag up to 10kg and one checked bag up to 20kg.
Yes, the following additional luggage options are available when booking a coach ticket from Florence Santa Maria Novella to Milan Centrale:
  • BlaBlaCar Bus
    • Additional luggage can be purchased for a fee.
  • FlixBus
    • Additional luggage can be purchased for a fee.
  • Itabus
    • 5€ per additional bag.
Yes, you can bring your pet on the coach from Florence Santa Maria Novella to Milan Centrale. The following conditions apply:
  • Marino Autolinee
    • Small pets allowed in carriers
    • larger pets must be leashed and muzzled.
  • FlixBus
    • Small pets in carriers allowed
    • guide dogs travel for free.
  • Itabus
    • Small pets allowed in carriers
    • larger pets must be leashed and muzzled.
You can reserve your seat on the coach from Florence Santa Maria Novella to Milan Centrale with the following coach company: FlixBus, Itabus, BlaBlaCar Bus, Marino Autolinee
Yes, there are USB plugs on board the coach from Florence Santa Maria Novella to Milan Centrale with the following coach company: FlixBus, Itabus, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi.
Yes, there is Wifi on board the coach from Florence Santa Maria Novella to Milan Centrale with the following coach company: FlixBus, Itabus, BlaBlaCar Bus, Marino Autolinee, Calanda Viaggi.

More options for your journey from Florence Santa Maria Novella to Milan Centrale

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