The cheapest and fastest buses from Isernia to Rome
Cheapest price
€14
Average price
€17
Fastest journey
2 h 25 m
Average duration
2 h 28 m
Buses per day
8
Distance
149 km
The best way to find a cheap bus ticket from Isernia to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Isernia to Rome will cost around €17 if you buy it on the day, but the cheapest tickets can be found for only €14.
Of the 8 buses that leave Isernia for Rome on Mon, Aug 24, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Mon, Aug 24 the direct buses cover the 149 km distance in an average of 2 h 28 m but if you time it right, some buses will get you there in just 2 h 25 m .
On Mon, Aug 24 the slowest buses will take 2 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
treno 23347 effettuato con bus CB7038:50 AM2h30Isernia station11:20 AMRome Termini€141One-way0 transfers
treno 23341 effettuato con bus CB7016:50 AM2h30Isernia station9:20 AMRome Termini€141One-way0 transfers
treno 23359 effettuato con bus CB7136:10 PM2h30Isernia station8:40 PMRome Termini€141One-way0 transfers
treno 23349 effettuato con bus CB7051:40 PM2h30Isernia station4:10 PMRome Tiburtina€141One-way0 transfers
treno 23361 effettuato con bus CB7158:40 PM2h30Isernia station11:10 PMRome Termini€141One-way0 transfers
0598:25 AM2h25Isernia, Piazza della Repubblica (F. Martino bus station)10:50 AMRoma, Autostazione Tiburtina€161One-way0 transfers
FlixBus11:35 AM2h25Isernia, Piazza della Repubblica (F. Martino bus station)2:00 PMRoma, Autostazione Tiburtina€341One-way0 transfers
treno 23347 effettuato con bus CB7038:50 AM2h30Isernia station11:20 AMRome Termini€141One-way0 transfers
treno 23341 effettuato con bus CB7016:50 AM2h30Isernia station9:20 AMRome Termini€141One-way0 transfers
treno 23359 effettuato con bus CB7136:10 PM2h30Isernia station8:40 PMRome Termini€141One-way0 transfers
Travel Information
Compare train and bus for Isernia to Rome
Omio recommends booking the train as it is the most popular option from Isernia to Rome among Omio's users. If you are prioritising price take the bus with prices starting from €5. For those with little time consider booking a bus which can get you there in 2h 20m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.0 - 0.1kg. The ticket price range depends on the travel mode: a bus costs an average of €5, and a train costs an average of €14.
Distance: 149 km
Compare bus with
| Bus | Most popular Train |
|---|---|
€12 Average price Cheapest | €18 Average price |
2h 50m Average total duration Fastest 2h 20m Onboard + 30m Additional time* | 3h 18m Average total duration 2h 48m Onboard + 30m Additional time* |
0.1 - 0.4kg CO2 emissions | 0.0 - 0.1kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Isernia to Rome bus times
The table below shows live departures for Isernia to Rome buses for tomorrow, Monday, August 24. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
treno 23341 effettuato con bus CB701 | 6:50 AM Isernia station | 2h30 | 9:20 AM Rome Termini | 0 transfersDirect | |
059 | 8:25 AM Isernia, Piazza della Repubblica (F. Martino bus station) | 2h25 | 10:50 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
treno 23347 effettuato con bus CB703 | 8:50 AM Isernia station | 2h30 | 11:20 AM Rome Termini | 0 transfersDirect | |
FlixBus | 11:35 AM Isernia, Piazza della Repubblica (F. Martino bus station) | 2h25 | 2:00 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
treno 23349 effettuato con bus CB705 | 1:40 PM Isernia station | 2h30 | 4:10 PM Rome Tiburtina | 0 transfersDirect | |
treno 23351 effettuato con bus CB707 | 3:15 PM Isernia station | 2h30 | 5:45 PM Rome Termini | 0 transfersDirect | |
treno 23359 effettuato con bus CB713 | 6:10 PM Isernia station | 2h30 | 8:40 PM Rome Termini | 0 transfersDirect | |
treno 23361 effettuato con bus CB715 | 8:40 PM Isernia station | 2h30 | 11:10 PM Rome Termini | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Isernia to Rome by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Aug 24
Aug 25
Aug 26
Aug 27
Aug 28
Aug 29
Aug 30
Why should you book Isernia to Rome buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of ATM Azienda di Trasporti Molisana S.p.A. to find the best option for your trip from Isernia to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Isernia to Rome.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Isernia to Rome.
Journey information
Overview: Bus from Isernia to Rome
Buses from Isernia to Rome run on average 10 times per day, taking around 2h 22m. Cheap bus tickets for this journey start at €8 if you book in advance.
There are 6 buses per day. The earliest bus runs at 00:15, the last at 23:56. The fastest bus covers the 149 km distance in 2h 10m.
Distance 149 km |
Average bus duration 2h 22m |
Cheapest ticket price €8 |
Buses per day 10 |
Direct buses 6 |
Fastest bus 2h 10m |
First bus 12:15 AM |
Last bus 11:56 PM |
Cheapest Month Mar |
Cheapest Day Sat |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Sun |
Least Busy Day Wed |
Best time to book 35 days |
Bus providers: FlixBus, BlaBlaCar, Marino Autolinee, ATM Azienda di Trasporti Molisana S.p.A. from Isernia to RomeYou can travel by bus between Isernia to Rome with FlixBus, BlaBlaCar, Marino Autolinee, ATM Azienda di Trasporti Molisana S.p.A. for as low as €8. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Marino Autolinee
BlaBlaCar
ATM Azienda di Trasporti Molisana S.p.A.
FAQs: Bus from Isernia to Rome
Find answers to the most common questions about traveling from Isernia to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Isernia to Rome
Most Isernia to Rome buses use the Isernia, Piazza della Repubblica (Autostazione F. Martino) to Roma, Autostazione Tiburtina station pair. Use this guide to compare Isernia and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Isernia station do buses to Rome leave from?
Getting to Isernia, Piazza della Repubblica (Autostazione F. Martino) from Isernia city centre
Isernia, Piazza della Repubblica (Autostazione F. Martino) bus station facilities and services
Isernia, Piazza della Repubblica (Autostazione F. Martino) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Nearby cafés and fast food outlets.
Wi-Fi and ATMs
Wi-Fi is available at Isernia, Piazza della Repubblica (Autostazione F. Martino). ATMs are aTM located near the entrance.
Tickets and information
Ticket office support is available at Isernia, Piazza della Repubblica (Autostazione F. Martino).
Parking, taxis and toilets
Available at Isernia, Piazza della Repubblica (Autostazione F. Martino): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Isernia, Piazza della Repubblica (Autostazione F. Martino): Wheelchair accessible facility.
Which Rome station do buses from Isernia arrive at?
Getting to Roma, Autostazione Tiburtina from Rome city centre
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina bus station facilities and services
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Cafes and vending machines available.
Wi-Fi and ATMs
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Tickets and information
Ticket office support is available at Roma, Autostazione Tiburtina.
Parking, taxis and toilets
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
More options for your journey from Isernia to Rome
Here are some other resources that might have the information you need
