The cheapest and fastest buses from Pisa Centrale to Rome
Cheapest price
€16
Average price
€29
Fastest journey
4 h 30 m
Average duration
4 h 51 m
Buses per day
4
Distance
264 km
The best way to find a cheap bus ticket from Pisa Centrale to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa Centrale to Rome will cost around €29 if you buy it on the day, but the cheapest tickets can be found for only €16.
Of the 4 buses that leave Pisa Centrale for Rome on Thu, Nov 06, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Nov 06 the direct buses cover the 264 km distance in an average of 4 h 51 m but if you time it right, some buses will get you there in just 4 h 30 m .
On Thu, Nov 06 the slowest buses will take 5 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








Travel Information
Compare train and bus for Pisa Centrale to Rome
Omio recommends booking the train as it is the most popular option from Pisa Centrale to Rome among Omio's users. If you are prioritising price take the bus with prices starting from €12. For those with little time consider booking a train which can get you there in 3h 5m. The ticket price range depends on the travel mode: a bus costs an average of €12, and a train costs an average of €17.
Distance: 264 km
Compare bus with
| Bus | Most popular Train |
|---|---|
€18 Average price Cheapest | €25 Average price |
5h 26m Average total duration 4h 56m Onboard + 30m Additional time* | 3h 35m Average total duration Fastest 3h 5m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Live departures
Pisa Centrale to Rome bus times
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 6:10 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 6h10 | 12:20 PM Roma, Autostazione Tiburtina | 1 transfer | |
207 | 7:20 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 6h00 | 1:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
207 | 7:55 AM Lucca, Stazione FS | 5h25 | 1:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 3:55 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 6h05 | 10:00 PM Roma, Autostazione Tiburtina | 1 transfer | |
118 | 5:15 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 5h25 | 10:40 PM Roma, Autostazione Tiburtina | 0 transfersDirect |
Find all the dates and times for this journey
Compare prices and tickets Pisa Centrale to Rome by train or bus
Nov 06
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Nov 14
Nov 15
Nov 16
Nov 17
Nov 18
Nov 19
Journey information
Overview: Bus from Pisa Centrale to Rome
Distance 264 km |
Average bus duration 4h 56m |
Cheapest ticket price €12 |
Buses per day 10 |
Direct buses 7 |
Fastest bus 4h 14m |
First bus 04:00 |
Last bus 21:30 |
Bus providers: FlixBus, Marino Autolinee, BlaBlaCar, Itabus, Busitalia from Pisa Centrale to RomeYou can travel by bus between Pisa Centrale to Rome with FlixBus, Marino Autolinee, BlaBlaCar, Itabus, Busitalia for as low as €12. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Marino Autolinee
Itabus
Busitalia
BlaBlaCar
FAQs: Bus from Pisa Centrale to Rome

To find the cheapest bus tickets for your trip from Pisa Centrale to Rome, follow these tips:
Start your search now and compare ticket prices to find the best deal!
popular bus stations
Popular bus stations from Pisa Centrale to Rome
- 06:00-23:00
- Free Wi-Fi
- Ristorante Italiano (in the station)
- Fast Food Express (in the station)
- Caffè del Terminal (in the station).
- Available outside the arrivals terminal.
- Elevators, ramps
- Available in the station.
- Bus: 520, 720 Train: Leonardo Express
More options for your journey from Pisa Centrale to Rome
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