The cheapest and fastest buses from Pisa Centrale to Rome
- Cheapest price on Nov 02
- €17
- Average ticket price on Nov 02
- €22
- Fastest journey on Nov 02
- 4 h 35 m
- Average journey duration on Nov 02
- 5 h 1 m
- Buses on Nov 02
- 11
- Distance
- 264 km
The best way to find a cheap bus ticket from Pisa Centrale to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa Centrale to Rome will cost around €22 if you buy it on the day, but the cheapest tickets can be found for only €17.
On Mon, Nov 02, we found 11 buses from Pisa Centrale to Rome, including 7 direct services.
On Mon, Nov 02 the direct buses cover the 264 km distance in an average of 5 h 1 m but if you time it right, some buses will get you there in just 4 h 35 m .
On Mon, Nov 02 the slowest buses will take 5 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
2078:20 AM 6h00 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 2:20 PM Roma, Autostazione Tiburtina €17 1 One-way 0 transfers
2078:55 AM 5h25 Lucca, Stazione FS 2:20 PM Roma, Autostazione Tiburtina €17 1 One-way 0 transfers
FlixBus6:05 AM 4h45 Pisa (Pisamover via San Giusto/Aurelia) 10:50 AM Roma, Autostazione Tiburtina €18 1 One-way 0 transfers
FlixBus5:25 PM 5h10 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 10:35 PM Roma, Autostazione Tiburtina €18 1 One-way 0 transfers
FlixBus · FlixBus7:15 AM 6h05 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 1:20 PM Roma, Autostazione Tiburtina €21 1 One-way 1 transfer
FlixBus10:00 PM 4h35 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 2:35 AM Roma, Autostazione Tiburtina €24 1 One-way 0 transfers
FlixBus6:05 AM 4h45 Pisa (Pisamover via San Giusto/Aurelia) 10:50 AM Roma, Autostazione Tiburtina €18 1 One-way 0 transfers
FlixBus1:25 PM 5h10 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 6:35 PM Roma, Autostazione Tiburtina €27 1 One-way 0 transfers
FlixBus5:25 PM 5h10 Pisa, Via delle Fiamme Gialle (Park Pietrasantina) 10:35 PM Roma, Autostazione Tiburtina €18 1 One-way 0 transfers
2078:55 AM 5h25 Lucca, Stazione FS 2:20 PM Roma, Autostazione Tiburtina €17 1 One-way 0 transfers
Journey information
Overview: Bus from Pisa Centrale to Rome
Buses from Pisa Centrale to Rome run on average 9 times per day, taking around 5h 13m. Cheap bus tickets for this journey start at €11 but you can travel from only €10 by train.
There are 6 buses per day. The earliest bus runs at 02:45, the last at 22:25. The fastest bus covers the 264 km distance in 4h 14m.
Distance 264 km |
Average bus duration 5h 13m |
Cheapest ticket price €11 |
Buses per day 9 |
Direct buses 6 |
Fastest bus 4h 14m |
First bus 2:45 AM |
Last bus 10:25 PM |
Cheapest Month Feb |
Cheapest Day Mon |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Sat |
Best time to book 28 days |
Frequently asked questions about your Pisa Centrale to Rome trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Pisa Centrale to Rome.
Live departures
Pisa Centrale to Rome bus times
The table below shows live departures for Pisa Centrale to Rome buses for today, Sunday, November 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 12:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 5h50 | 5:50 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus | 12:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 5h25 | 5:25 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus | 1:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 5h10 | 6:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 5:10 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 4h40 | 9:50 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus | 5:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 5h10 | 10:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 5:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 6h20 | 11:45 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus | 10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 4h35 | 2:35 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
| Monday, November 2 | |||||
FlixBus | 12:25 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 5h30 | 5:55 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 6:05 AM Pisa (Pisamover via San Giusto/Aurelia) | 4h45 | 10:50 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 7:15 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 6h05 | 1:20 PM Roma, Autostazione Tiburtina | 1 transfer | |
207 | 8:20 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 6h00 | 2:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
207 | 8:55 AM Lucca, Stazione FS | 5h25 | 2:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 9:40 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 6h25 | 4:05 PM Roma, Autostazione Tiburtina | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Pisa Centrale to Rome buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Marino Autolinee, Busitalia or Infobus to find the best option for your trip from Pisa Centrale to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa Centrale to Rome.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Marino Autolinee, Busitalia or Infobus to find the best option for your trip from Pisa Centrale to Rome.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa Centrale to Rome.
Bus providers: FlixBus, Marino Autolinee, Busitalia, Infobus from Pisa Centrale to RomeYou can travel by bus between Pisa Centrale to Rome with FlixBus, Marino Autolinee, Busitalia, Infobus for as low as €10. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Marino Autolinee
Infobus
Busitalia
Companies, tickets, and onboard amenities between Pisa Centrale and Rome
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- Busitalia
- People with disabilities or reduced mobility have the right to free transport of their folding wheelchair or mobility aids in the luggage compartment, and assistance dogs and companions travel free of charge if continuous assistance is required.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- Busitalia
- Vouchers are issued for cancellations made before departure, which can be used for future purchases within one year.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- Busitalia
- One piece of hand luggage (50x30x25 cm, max 10 kg) and one piece of hold luggage (80x50x30 cm, max 20 kg) are included free of charge.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- Busitalia
- An additional hold luggage item (80x50x30 cm, max 20 kg) or special baggage (total volume not exceeding 240 cm, max 30 kg) can be purchased.
- FlixBus
- Additional luggage can be purchased for a fee.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- Busitalia
- Small pets (cats or small dogs) are allowed free of charge if held and not disturbing other customers
- medium and large dogs require a ticket and must have a muzzle and leash.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
FAQs: Bus from Pisa Centrale to Rome
Find answers to the most common questions about traveling from Pisa Centrale to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Pisa Centrale to Rome
Most Pisa Centrale to Rome buses use the Pisa, Via delle Fiamme Gialle (Park Pietrasantina) to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Pisa Centrale and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Getting to Roma, Autostazione Tiburtina from Rome city centre
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina bus station facilities and services
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Cafes and vending machines available.
Wi-Fi and ATMs
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Tickets and information
Ticket office support is available at Roma, Autostazione Tiburtina.
Parking, taxis and toilets
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Getting to Roma, Autostazione (Metro Anagnina) from Rome city centre
Getting to Roma from Rome city centre
Roma is 1 km from Rome city centre. Public transport options include:
Roma bus station facilities and services
Roma has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Several fast-food options and a cafe.
Wi-Fi and ATMs
Free public WiFi available in waiting areas. ATMs are aTMs located at entrance area.
Tickets and information
Ticket office support is available at Roma.
Parking, taxis and toilets
Available at Roma: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Roma: Wheelchair accessible entrances and restrooms.
More options for your journey from Pisa Centrale to Rome
Here are some other resources that might have the information you need
