The cheapest and fastest buses from Pisa Centrale to Rome
Cheapest price
€23
Average price
€29
Fastest journey
5 h 9 m
Average duration
9 h 5 m
Buses per day
4
Distance
264 km
The best way to find a cheap bus ticket from Pisa Centrale to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa Centrale to Rome will cost around €29 if you buy it on the day, but the cheapest tickets can be found for only €23.
Of the 4 buses that leave Pisa Centrale for Rome on Wed, Feb 04, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Feb 04 the direct buses cover the 264 km distance in an average of 9 h 5 m but if you time it right, some buses will get you there in just 5 h 9 m .
On Wed, Feb 04 the slowest buses will take 15 h and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.








Travel Information
Compare train and bus for Pisa Centrale to Rome
Omio recommends booking the train as it is the most popular option from Pisa Centrale to Rome among Omio's users. If you are prioritising price take the bus with prices starting from €12. For those with little time consider booking a train which can get you there in 3h 5m. The ticket price range depends on the travel mode: a bus costs an average of €12, and a train costs an average of €17.
Distance: 264 km
Compare bus with
| Bus | Most popular Train |
|---|---|
€18 Average price Cheapest | €25 Average price |
5h 26m Average total duration 4h 56m Onboard + 30m Additional time* | 3h 35m Average total duration Fastest 3h 5m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Live departures
Pisa Centrale to Rome bus times
The table below shows live departures for Pisa Centrale to Rome buses for today, Tuesday, February 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 12:25 PM Pisa, Aeroporto Parcheggio Aurelia | 5h10 | 5:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 4:20 PM Pisa, Aeroporto Parcheggio Aurelia | 5h40 | 10:00 PM Roma, Autostazione Tiburtina | 1 transfer | |
![]() | 6:45 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 4h14 | 10:59 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
| Wednesday, February 4 | |||||
![]() | 10:37 AM Pisa Centrale | 5h09 | 3:46 PM Rome | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa Centrale to Rome by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 04
Feb 05
Feb 06
Feb 07
Feb 08
Feb 09
Feb 10
Feb 11
Feb 12
Feb 13
Feb 14
Feb 15
Feb 16
Feb 17
Feb 18
Feb 19
Feb 20
Feb 21
Feb 22
Feb 23
Feb 24
Journey information
Overview: Bus from Pisa Centrale to Rome
Buses from Pisa Centrale to Rome run on average 10 times per day, taking around 4h 56m. Cheap bus tickets for this journey start at €12 if you book in advance.
There are 7 buses per day. The earliest bus runs at 04:00, the last at 21:30. The fastest bus covers the 264 km distance in 4h 14m.
Distance 264 km |
Average bus duration 4h 56m |
Cheapest ticket price €12 |
Buses per day 10 |
Direct buses 7 |
Fastest bus 4h 14m |
First bus 04:00 |
Last bus 21:30 |
Bus providers: FlixBus, Marino Autolinee, BlaBlaCar, Itabus, Busitalia from Pisa Centrale to RomeYou can travel by bus between Pisa Centrale to Rome with FlixBus, Marino Autolinee, BlaBlaCar, Itabus, Busitalia for as low as €12. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Marino Autolinee
Itabus
Busitalia
BlaBlaCar
FAQs: Bus from Pisa Centrale to Rome
Find answers to the most common questions about traveling from Pisa Centrale to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Pisa Centrale to Rome
- 06:00-23:00
- Free Wi-Fi
- Ristorante Italiano (in the station)
- Fast Food Express (in the station)
- Caffè del Terminal (in the station).
- Available outside the arrivals terminal.
- Elevators, ramps
- Available in the station.
- Bus: 520, 720 Train: Leonardo Express
More options for your journey from Pisa Centrale to Rome
Here are some other resources that might have the information you need


