The cheapest and fastest buses from Prague to Rome
Cheapest price
€100
Average price
€158
Fastest journey
19 h 35 m
Average duration
19 h 54 m
Buses per day
34
Distance
923 km
The best way to find a cheap bus ticket from Prague to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Rome will cost around €158 if you buy it on the day, but the cheapest tickets can be found for only €100.
Of the 34 buses that leave Prague for Rome on Thu, Aug 13, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Aug 13 the direct buses cover the 923 km distance in an average of 19 h 54 m but if you time it right, some buses will get you there in just 19 h 35 m .
On Thu, Aug 13 the slowest buses will take 20 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus5:45 PM21h00Prague, Central Train Station2:45 PMRoma, Autostazione Tiburtina€1001One-way0 transfers
FlixBus5:30 PM21h15Praha, ÚAN Florenc2:45 PMRoma, Autostazione Tiburtina€1001One-way0 transfers
FlixBus · FlixBus5:45 PM19h35Praha, Na Knížecí1:20 PMRoma, Autostazione Tiburtina€1431One-way1 transfer
FlixBus · FlixBus · FlixBus3:05 PM22h15Praha, Zličín1:20 PMRoma, Autostazione Tiburtina€1471One-way2 transfers
FlixBus · FlixBus · FlixBus8:30 AM25h00Praha, Roztyly9:30 AMRoma, Autostazione Tiburtina€1481One-way2 transfers
FlixBus · FlixBus5:45 PM19h35Praha, Na Knížecí1:20 PMRoma, Autostazione Tiburtina€1431One-way1 transfer
FlixBus · FlixBus11:15 AM19h50Prague, Central Train Station7:05 AMRoma, Autostazione Tiburtina€1821One-way1 transfer
FlixBus · FlixBus9:25 PM20h00Praha, ÚAN Florenc5:25 PMRoma, Autostazione Tiburtina€1561One-way1 transfer
FlixBus · FlixBus · FlixBus4:15 PM20h00Prague, Central Train Station12:15 PMRoma, Autostazione (Metro Anagnina)€1491One-way2 transfers
FlixBus · FlixBus11:00 AM20h05Praha, ÚAN Florenc7:05 AMRoma, Autostazione Tiburtina€1821One-way1 transfer
Travel Information
Compare bus and flight for Prague to Rome
Omio recommends booking the flight as it is the most popular option from Prague to Rome among Omio's users. If you are prioritising price take the bus with prices starting from €56. For those with little time consider booking a flight which can get you there in 3h 35m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 0.9 - 2.3kg. The ticket price range depends on the travel mode: a bus costs an average of €56, and a flight costs an average of €23.
Distance: 923 km
Compare bus with
| Bus | Most popular Flight |
|---|---|
€98 Average price Cheapest | €158 Average price |
15h 10m Average total duration 14h 40m Onboard + 30m Additional time* | 6h 35m Average total duration Fastest 3h 35m Onboard + 3h 0m Additional time* |
0.9 - 2.3kg CO2 emissions Lowest | 2.8 - 5.5kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Prague to Rome bus times
The table below shows live departures for Prague to Rome buses for today, Wednesday, August 12. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 5:50 AM Prague, Central Train Station | 27h40 | 9:30 AM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:00 AM Prague, Central Train Station | 21h10 | 6:10 AM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:40 AM Praha, Na Knížecí | 26h35 | 12:15 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus | 9:50 AM Praha, ÚAN Florenc | 23h30 | 9:20 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 10:05 AM Prague, Central Train Station | 23h15 | 9:20 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:55 AM Praha, Na Knížecí | 22h35 | 9:30 AM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 11:00 AM Praha, Roztyly | 27h45 | 2:45 PM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus | 12:50 PM Praha, M. Horákové (Hradčanská) | 24h30 | 1:20 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 12:50 PM Praha, M. Horákové (Hradčanská) | 26h15 | 3:05 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus | 12:50 PM Praha, ÚAN Florenc | 20h40 | 9:30 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 1:05 PM Prague, Central Train Station | 20h25 | 9:30 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 2:30 PM Praha, Černý Most | 22h50 | 1:20 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 2:30 PM Praha, Černý Most | 24h35 | 3:05 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 3:05 PM Praha, Zličín | 22h15 | 1:20 PM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:00 PM Praha, ÚAN Florenc | 20h15 | 12:15 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 4:15 PM Prague, Central Train Station | 20h00 | 12:15 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus · FlixBus | 5:15 PM Praha, ÚAN Florenc | 21h50 | 3:05 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus | 5:30 PM Praha, ÚAN Florenc | 21h15 | 2:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus · FlixBus | 5:30 PM Prague, Central Train Station | 21h35 | 3:05 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus | 5:30 PM Praha, ÚAN Florenc | 24h20 | 5:50 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 5:45 PM Prague, Central Train Station | 21h00 | 2:45 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 5:45 PM Praha, Na Knížecí | 19h35 | 1:20 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 5:45 PM Praha, Na Knížecí | 21h20 | 3:05 PM Roma, Autostazione (Metro Anagnina) | 2 transfers | |
FlixBus · FlixBus | 5:45 PM Prague, Central Train Station | 24h05 | 5:50 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus · FlixBus | 6:45 PM Praha, Roztyly | 22h40 | 5:25 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 7:25 PM Praha, Zličín | 23h20 | 6:45 PM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus · FlixBus | 9:50 PM Praha, Na Knížecí | 25h10 | 11:00 PM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus | 9:55 PM Praha, ÚAN Florenc | 22h40 | 8:35 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 10:25 PM Praha, M. Horákové (Hradčanská) | 24h35 | 11:00 PM Roma, Autostazione Tiburtina | 2 transfers | |
FlixBus · FlixBus | 11:40 PM Praha, ÚAN Florenc | 23h20 | 11:00 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:50 PM Prague, Central Train Station | 22h00 | 9:50 PM Roma, Autostazione Tiburtina | 2 transfers | |
| Thursday, August 13 | |||||
FlixBus · FlixBus | 2:30 AM Prague, Central Train Station | 20h30 | 11:00 PM Roma, Autostazione Tiburtina | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Prague to Rome by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Aug 12
Aug 13
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Sep 01
Why should you book Prague to Rome buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and flight to ensure you get the best deal for traveling from Prague to Rome.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus and flight to find the ideal travel option from Prague to Rome.
Journey information
Overview: Bus from Prague to Rome
Buses from Prague to Rome run on average 38 times per day, taking around 14h 40m. Cheap bus tickets for this journey start at €56 but you can travel from only €23 by flight.
There are 2 buses per day. The earliest bus runs at 00:10, the last at 23:50. The fastest bus covers the 923 km distance in 19h 15m.
Distance 923 km |
Average bus duration 14h 40m |
Cheapest ticket price €56 |
Buses per day 38 |
Direct buses 2 |
Fastest bus 19h 15m |
First bus 12:10 AM |
Last bus 11:50 PM |
Cheapest Month Mar |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 42 days |
Bus providers: FlixBus from Prague to RomeYou can travel by bus between Prague to Rome with FlixBus for as low as €23. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
FAQs: Bus from Prague to Rome
Find answers to the most common questions about traveling from Prague to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Prague to Rome
Most Prague to Rome buses use the Praha, Hlavní Nádraží to Roma, Autostazione Tiburtina station pair, with some services arriving at Roma, Autostazione (Metro Anagnina). Use this guide to compare Prague and Rome bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Prague station do buses to Rome leave from?
Getting to Praha, Hlavní Nádraží from Prague city centre
Praha, Hlavní Nádraží is 1 km from Prague city centre. Public transport options include:
Praha, Hlavní Nádraží bus station facilities and services
Praha, Hlavní Nádraží has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Czech Bistro (in the station), Fast Food Express (in the station), Bohemian Café (0.2 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and ticketing area.
Tickets and information
Ticket office support is available at Praha, Hlavní Nádraží.
Parking, taxis and toilets
Available at Praha, Hlavní Nádraží: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Hlavní Nádraží: Elevators, ramps.
Getting to Praha, ÚAN Florenc from Prague city centre
Praha, ÚAN Florenc is 1 km from Prague city centre. Public transport options include:
Praha, ÚAN Florenc bus station facilities and services
Praha, ÚAN Florenc has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Florenc (in the station), Bistro Florenc (0.2 km), Restaurace U Rozvařilů (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located inside the station, offering multiple currency options.
Tickets and information
Ticket office support is available at Praha, ÚAN Florenc.
Parking, taxis and toilets
Available at Praha, ÚAN Florenc: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, ÚAN Florenc: Elevators, ramps.
Getting to Praha, Na Knížecí from Prague city centre
Praha, Na Knížecí is 2 km from Prague city centre. Public transport options include:
Praha, Na Knížecí bus station facilities and services
Praha, Na Knížecí has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, and WC.
Food and drink
Food options include: Café Na Knížecí (in the station), Bistro Praha (0.2 km), Restaurace U Knížete (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the entrance.
Parking, taxis and toilets
Available at Praha, Na Knížecí: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Praha, Na Knížecí: Elevators, ramps.
Which Rome station do buses from Prague arrive at?
Getting to Roma, Autostazione Tiburtina from Rome city centre
Roma, Autostazione Tiburtina is 4 km from Rome city centre. Public transport options include:
Roma, Autostazione Tiburtina bus station facilities and services
Roma, Autostazione Tiburtina has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Cafes and vending machines available.
Wi-Fi and ATMs
Wi-Fi is available at Roma, Autostazione Tiburtina. ATMs are aTM available near ticket office.
Tickets and information
Ticket office support is available at Roma, Autostazione Tiburtina.
Parking, taxis and toilets
Available at Roma, Autostazione Tiburtina: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Roma, Autostazione Tiburtina: Wheelchair accessible entrances and facilities.
Getting to Roma, Autostazione (Metro Anagnina) from Rome city centre
Getting to Ciampino, Aeroporto Internazionale di Roma–Ciampino "G. B. Pastine" from Rome city centre
Most popular bus connections from Prague
More options for your journey from Prague to Rome
Here are some other resources that might have the information you need

