The cheapest and fastest buses from Lyon to Santander
Cheapest price
€93
Average price
€93
Fastest journey
18 h 5 m
Average duration
18 h 5 m
Buses per day
1
Distance
730 km
The best way to find a cheap bus ticket from Lyon to Santander is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Santander will cost around €93 if you buy it on the day, but the cheapest tickets can be found for only €93.
It's difficult to get from Lyon to Santander without transferring at least once.
FlixBus · FlixBus
FlixBus · FlixBusTravel Information
Compare bus and flight for Lyon to Santander
Omio recommends booking the bus as it is the most popular option from Lyon to Santander among Omio's users. If you are prioritising price take the bus with prices starting from €40. For those with little time consider booking a flight which can get you there in 3h 0m. The ticket price range depends on the travel mode: a bus costs an average of €40, and a flight costs an average of €72.
Distance: 730 km
Compare bus with
Most popular Bus | Flight |
|---|---|
€57 Average price Cheapest | €265 Average price |
15h 32m Average total duration 15h 2m Onboard + 30m Additional time* | 6h 0m Average total duration Fastest 3h 0m Onboard + 3h 0m Additional time* |
![]() Most popular bus company | ![]() Most popular airline |
Direct Options | Direct Options |
Live departures
Lyon to Santander bus times
The table below shows live departures for Lyon to Santander buses for tomorrow, Saturday, January 31. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 2:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 18h05 | 8:20 AM Santander, Estación de Autobuses | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon to Santander by bus or flight
Compare bus and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jan 31
Feb 01
Feb 02
Feb 03
Feb 04
Feb 05
Feb 06
Journey information
Overview: Bus from Lyon to Santander
Buses from Lyon to Santander run on average 2 times per day, taking around 15h 2m. Cheap bus tickets for this journey start at €40 if you book in advance.
The earliest bus runs at 00:10, the last at 23:00. The fastest bus covers the 730 km distance in 12h 45m.
Distance 730 km |
Average bus duration 15h 2m |
Cheapest ticket price €40 |
Buses per day 2 |
Fastest bus 12h 45m |
First bus 00:10 |
Last bus 23:00 |
Bus providers: Alsa, FlixBus, BlaBlaCar Bus, Union Ivkoni - Unibus from Lyon to SantanderYou can travel by bus between Lyon to Santander with Alsa, FlixBus, BlaBlaCar Bus, Union Ivkoni - Unibus for as low as €40. When you search for schedules and tickets, Omio will show you the best journey
Alsa
FlixBus
BlaBlaCar Bus
Union Ivkoni - Unibus
FAQs: Bus from Lyon to Santander
Find answers to the most common questions about traveling from Lyon to Santander by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santander, this guide helps you travel smarter and with confidence.

- Alsa
- Assistance
- Priority boarding
- Accessible seating.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Alsa
- You can cancel your ticket up to 48 hours before departure for a partial refund. Changes allowed for a fee.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Alsa
- One carry-on bag up to 10kg and one checked bag up to 25kg.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Alsa
- Additional luggage can be purchased for a fee.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Alsa
- Small pets allowed in carriers
- larger pets must travel in the hold.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Lyon to Santander
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
Most popular bus connections from Lyon
More options for your journey from Lyon to Santander
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