The cheapest and fastest buses from Lyon to Santander
Cheapest price on Sep 15
€42
Average ticket price on Sep 15
€52
Fastest journey on Sep 15
18 h 5 m
Average journey duration on Sep 15
20 h 38 m
Buses on Sep 15
3
Distance
730 km
The best way to find a cheap bus ticket from Lyon to Santander is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Santander will cost around €52 if you buy it on the day, but the cheapest tickets can be found for only €42.
It's difficult to get from Lyon to Santander without transferring at least once.
Normal · Normal5:15 AM20h00Lyon, Perrache Bus Station1:15 AMSantander, Estación de Autobuses€421One-way1 transfer
5130 · 460510:40 AM23h49Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)10:29 AMSantander, Estación de Autobuses€481One-way1 transfer
FlixBus · FlixBus3:15 PM18h05Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)9:20 AMSantander, Estación de Autobuses€651One-way1 transfer
FlixBus · FlixBus3:15 PM18h05Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)9:20 AMSantander, Estación de Autobuses€651One-way1 transfer
Normal · Normal5:15 AM20h00Lyon, Perrache Bus Station1:15 AMSantander, Estación de Autobuses€421One-way1 transfer
5130 · 460510:40 AM23h49Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)10:29 AMSantander, Estación de Autobuses€481One-way1 transfer
Travel Information
Compare train, bus, and flight for Lyon to Santander
Omio recommends booking the bus as it is the most popular option from Lyon to Santander among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €63 For those with little time, consider booking a flight, which has an average total journey time of 4h 55m. Average ticket prices depend on the travel mode: a bus costs an average of €63, while a flight costs an average of €260.
Distance: 730 km
Compare bus with
Most popular Bus | Flight | Train | Driving |
|---|---|---|---|
€63 Average price Cheapest | €260 Average price | €168 Average price | €254 Average price (fuel + tolls) |
15h 39m Average total duration 15h 9m Onboard + 30m Additional time* | 4h 55m Average total duration Fastest 2h 55m Onboard + 2h 0m Additional time* | 23h 13m Average total duration 22h 43m Onboard + 30m Additional time* | 9h 56m Average total duration (door-to-door) |
Direct Options | Direct Options | Direct Options | Direct Options |
This is compared to other travel options from Lyon to Santander:
A bus is €105 less than a train for this route with tickets for a train from Lyon to Santander costing on average €168.
A bus is €197 less than a flight for this route with tickets for a flight from Lyon to Santander costing on average €260.
Other travel options to Santander take longer:
Bus takes on average 15h 9m.
Train takes on average 22h 43m.
Live departures
Lyon to Santander bus times
The table below shows live departures for Lyon to Santander buses for tomorrow, Tuesday, September 15. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
Normal · Normal | 5:15 AM Lyon, Perrache Bus Station | 20h00 | 1:15 AM Santander, Estación de Autobuses | 1 transfer | |
5130 · 4605 | 10:40 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 23h49 | 10:29 AM Santander, Estación de Autobuses | 1 transfer | |
FlixBus · FlixBus | 3:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 18h05 | 9:20 AM Santander, Estación de Autobuses | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Lyon to Santander by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sep 15
Sep 16
Sep 17
Sep 18
Sep 19
Sep 20
Sep 21
Why should you book Lyon to Santander buses with Omio?
Why book with Omio vs Alsa?
- Compare with other providers: On Omio, you can not only buy tickets for Alsa, but also compare tickets for the likes of FlixBus, BlaBlaCar Bus or Internorte to find the best option for your trip from Lyon to Santander.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Alsa with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Lyon to Santander.
Why book with Omio over Checkmybus, Rome2rio or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus, BlaBlaCar Bus or Internorte to find the best option for your trip from Lyon to Santander.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Lyon to Santander.
Journey information
Overview: Bus from Lyon to Santander
Buses from Lyon to Santander run on average 2 times per day, taking around 15h 9m. Cheap bus tickets for this journey start at €42 if you book in advance.
The earliest bus runs at 01:00, the last at 20:50. The fastest bus covers the 730 km distance in 14h 45m.
Distance 730 km |
Average bus duration 15h 9m |
Cheapest ticket price €42 |
Buses per day 2 |
Fastest bus 14h 45m |
First bus 1:00 AM |
Last bus 8:50 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Mon |
Best time to book 14 days |
Bus providers: Alsa, FlixBus, BlaBlaCar Bus, Internorte from Lyon to SantanderYou can travel by bus between Lyon to Santander with Alsa, FlixBus, BlaBlaCar Bus, Internorte for as low as €42. When you search for schedules and tickets, Omio will show you the best journey
Alsa
FlixBus
BlaBlaCar Bus
Internorte
FAQs: Bus from Lyon to Santander
Find answers to the most common questions about traveling from Lyon to Santander by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Santander, this guide helps you travel smarter and with confidence.

- Alsa
- Assistance
- Priority boarding
- Accessible seating.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Alsa
- You can cancel your ticket up to 48 hours before departure for a partial refund. Changes allowed for a fee.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Alsa
- One carry-on bag up to 10kg and one checked bag up to 25kg.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Alsa
- Additional luggage can be purchased for a fee.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Alsa
- Small pets allowed in carriers
- larger pets must travel in the hold.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Lyon to Santander
Most Lyon to Santander buses use the Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) to Santander, Estación de Autobuses station pair. Use this guide to compare Lyon and Santander bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Lyon station do buses to Santander leave from?
Getting to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) from Lyon city centre
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) bus station facilities and services
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Tickets and information
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Parking, taxis and toilets
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Getting to Lyon, Gare Routière de Perrache from Lyon city centre
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache bus station facilities and services
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance.
Tickets and information
Ticket office support is available at Lyon, Gare Routière de Perrache.
Parking, taxis and toilets
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Getting to Lyon, Gare Perrache from Lyon city centre
Lyon, Gare Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Perrache bus station facilities and services
Lyon, Gare Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Café de la Gare (in the station), Bistro Lyonnais (0.2 km), Fast Food Express (0.3 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and in the shopping area.
Tickets and information
Ticket office support is available at Lyon, Gare Perrache.
Parking, taxis and toilets
Available at Lyon, Gare Perrache: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, Gare Perrache: Elevators, ramps.
Most popular bus connections from Lyon
More options for your journey from Lyon to Santander
Here are some other resources that might have the information you need
