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The cheapest and fastest buses from Lyon to Brussels
Showing times and prices for Feb 21
Cheapest price
€40
Average price
€81
Fastest journey
7 h 10 m
Average duration
9 h 7 m
Buses per day
15
Distance
569 km
Cheap tickets
The best way to find a cheap bus ticket from Lyon to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Brussels will cost around €81 if you buy it on the day, but the cheapest tickets can be found for only €40.
Fast buses
Of the 15 buses that leave Lyon for Brussels on Sat, Feb 21, 4 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Feb 21 the direct buses cover the 569 km distance in an average of 9 h 7 m but if you time it right, some buses will get you there in just 7 h 10 m .
On Sat, Feb 21 the slowest buses will take 10 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
58074 · 5033712:00PM11h35
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)11:35PMBrussels, Brussels South (Gare du Midi)
€401One-way
1 transfer
50470 · 161303:50PM10h23
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)02:13AMBrussels, Brussels South (Gare du Midi)
€421One-way
1 transfer
10:00AM7h50
Lyon05:50PMBrussels
€491One-way
0 transfers
10:20AM7h10
Lyon05:30PMBrussels
€581One-way
0 transfers
FlixBus09:25PM10h50
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)08:15AMBrussels, Brussels South (Gare du Midi)
€651One-way
0 transfers
10:20AM7h10
Lyon05:30PMBrussels
€581One-way
0 transfers
10:00AM7h50
Lyon05:50PMBrussels
€491One-way
0 transfers
5082910:45PM9h40
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)08:25AMBrussels, Brussels South (Gare du Midi)
€1611One-way
0 transfers
50470 · 161303:50PM10h23
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)02:13AMBrussels, Brussels South (Gare du Midi)
€421One-way
1 transfer
94742 · 165701:30AM10h30
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan)12:00PMBrussels, Brussels South (Gare du Midi)
€981One-way
1 transfer
Travel Information
Compare train, bus, and flight for Lyon to Brussels
Omio recommends booking the train as it is the most popular option from Lyon to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €19. For those with little time consider booking a flight which can get you there in 1h 58m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of €19, and a flight costs an average of €96.
Distance: 569 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€41 Average price Cheapest | €104 Average price | €229 Average price |
8h 27m Average total duration 7h 57m Onboard + 30m Additional time* | 6h 8m Average total duration 5h 38m Onboard + 30m Additional time* | 4h 58m Average total duration Fastest 1h 58m Onboard + 3h 0m Additional time* |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.4kg CO2 emissions |
Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Lyon to Brussels bus times
The table below shows live departures for Lyon to Brussels buses for today, Friday, February 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at 10:50 PM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 11:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 12h10 | 11:20 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| 11:30 PM Lyon | 11h30 | 11:00 AM Brussels | 0 transfersDirect | |
| 11:50 PM Lyon | 11h30 | 11:20 AM Brussels | 0 transfersDirect | |
| FlixBus · FlixBus | 11:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 11h55 | 11:45 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| Saturday, February 21 | |||||
| 94742 · 1657 | 12:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 10h30 | 11:00 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus | 12:45 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 11h55 | 12:40 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| 5288 · 1466 | 1:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 11h05 | 12:30 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus | 4:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 12h30 | 4:55 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus | 8:10 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 12h25 | 8:35 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus | 10:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 11h40 | 10:30 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| 58074 · 50337 | 11:00 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 11h35 | 10:35 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus | 2:15 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 11h50 | 2:05 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| 50470 · 1613 | 2:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 10h23 | 1:13 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus | 8:25 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 10h50 | 7:15 AM Brussels, Brussels South (Gare du Midi) | 0 transfersDirect | |
| 50829 | 9:45 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 9h40 | 7:25 AM Brussels, Brussels South (Gare du Midi) | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Lyon to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Lyon to Brussels buses with Omio?
BlaBlaCar Bus as well as FlixBus or TGV INOUI offer buses services from Lyon to Brussels.
Omio is an official ticket reseller for all your travel options from Lyon to Brussels.
Why book with Omio vs BlaBlaCar Bus?
- Compare with other providers: On Omio, you can not only buy tickets for BlaBlaCar Bus, but also compare tickets for the likes of FlixBus or TGV INOUI to find the best option for your trip from Lyon to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare BlaBlaCar Bus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Lyon to Brussels.
Why book with Omio over Checkmybus, Wanderu or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus or TGV INOUI to find the best option for your trip from Lyon to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Lyon to Brussels.
Journey information
Overview: Bus from Lyon to Brussels
France
Belgium
Buses from Lyon to Brussels run on average 16 times per day, taking around 7h 57m. Cheap bus tickets for this journey start at €19 if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 569 km distance in 9h 40m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Distance 569 km |
Average bus duration 7h 57m |
Cheapest ticket price €19 |
Buses per day 16 |
Direct buses 3 |
Fastest bus 9h 40m |
First bus 00:10 |
Last bus 23:55 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Bus providers: BlaBlaCar Bus, FlixBus, BlaBlaCar, TGV INOUI from Lyon to BrusselsYou can travel by bus between Lyon to Brussels with BlaBlaCar Bus, FlixBus, BlaBlaCar, TGV INOUI for as low as €19. When you search for schedules and tickets, Omio will show you the best journey
TGV INOUI
About
SNCF's TGV INOUI is a premium high-speed train service operating across France and to other European cities. Launched in 2017, it aims to provide an enhanced travel experience with greater comfort, connectivity, and services compared to traditional TGV services. TGV INOUI trains offer features like adjustable seats, electrical outlets, fold-down tables, and dedicated luggage spaces. Passengers can enjoy onboard Wi-Fi and access to the TGV INOUI portal for entertainment and journey information. The service also includes a \Bistro TGV INOUI\" for dining, with options for online ordering. SNCF is also introducing a new generation of TGV INOUI trains from 2026, which will be more modular, energy-efficient, and 97% recyclable."
Luggage & cancellation policy
Average Duration
3h 43m
Cheapest Price
€46
Luggage included
1 hand luggage + 2 pieces of luggage free of charge
Luggage storage
Overhead racks, end of carriages, between seats
Cancellation Policy
Refund conditions depend on ticket type
Refund
Full refund if train canceled
Amenities on board the bus
Wifi
Food sold onboard
Restaurant car (not all trains), at-seat service in 1st class, snack bar/cafe
Seat reservation
Second class: Optional, additional fee. First class: Included in ticket price
Toilets
USB plugs
Accessibility
Wheelchair spaces, accessible toilets, boarding assistance available
Pets
Small pets in carriers: Free. Large dogs: Paid ticket required. Guide dogs: Free
Quiet zone
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
10h 45m
Cheapest Price
€32
FlixBus frequency
9 a day
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Pets
Small pets in carriers allowed; guide dogs travel for free.
BlaBlaCar Bus
About
BlaBlaCar Bus (formerly known as Ouibus or iDBUS) is a long-distance coach company operating in 10 European countries and connecting over 300 destinations. A subsidiary of the French carpooling company BlaBlaCar, it offers comfortable travel with standard amenities such as air conditioning, toilets, USB and power outlets for charging devices, extra legroom, and adjustable seats. Free Wi-Fi is available on select routes. BlaBlaCar Bus offers only a Standard ticket type, which allows passengers to bring one carry-on bag and up to two checked bags per person.
Luggage & cancellation policy
Average Duration
9h 40m
Cheapest Price
€19
BlaBlaCar Bus frequency
7 a day
Luggage included
One carry-on bag up to 7kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating options.
BlaBlaCar
About
BlaBlaCar is a French online marketplace for carpooling, connecting drivers with empty seats and passengers traveling to the same destination to share costs. Founded in 2006, it operates in Europe and Latin America, boasting 26 million active members. The platform also includes BlaBlaCar Bus, an intercity bus service. BlaBlaCar's name comes from its rating system for drivers' chattiness: \Bla\" for quiet, \"BlaBla\" for talkative, and \"BlaBlaBla\" for very chatty. The company aims to be the leading marketplace for shared travel, offering affordable and sustainable solutions by combining carpooling with bus journeys."
Luggage & cancellation policy
BlaBlaCar frequency
2 a day
FAQs: Bus from Lyon to Brussels
Find answers to the most common questions about traveling from Lyon to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.
Cheap coach tickets from Lyon to Brussels can start from as little as €19 when you book in advance. The average coach ticket price for Lyon to Brussels is €41; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by coach from Lyon to Brussels is 9h 40m to travel the 569 km long trip. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest coach from Lyon to Brussels leaves at 12:10 AM. Plan your trip with the Journey Planner from Omio.
The latest coach from Lyon to Brussels leaves at 11:55 PM.
Yes, there are 3 direct coaches a day from Lyon to Brussels with BlaBlaCar Bus, FlixBus, BlaBlaCar, TGV INOUI. Schedules can vary on holidays or weekends with fewer direct coaches.
When taking a coach from Lyon to Brussels, you can count on BlaBlaCar Bus, FlixBus, BlaBlaCar, TGV INOUI for the best way to get you to Brussels. You can also check all possible coach companies who offer a service between Lyon and Brussels and compare the amenities they offer before buying a coach ticket.
When departing from Lyon , you have various coach station options to start your trip from including Lyon, Perrache Bus Station, Lyon, St Exupéry Aéroport, Givors, Plaza Jean Berry, Colombier-Saugnieu, Lyon - Saint-Exupéry Airport (Arrivée T1), Lyon, Gare Perrache, Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) . When arriving in Brussels , you can end your trip in coach stations like Brussels, Brussels South (Gare du Midi), Bruxelles, Gare du Nord, Brussels, Gare Du Midi, Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord), Schaerbeek, Rue du Progrès (Gare du Nord), Brussels, Gare Centrale, Brussels, Avenue des Magnolias (King Baudouin), Zaventem, Brussels Airport Leopoldlaan (Parking P16) .Passengers board the coach most frequently from Lyon, Perrache Bus Station, which is located around 1 away from the city centre, and they get off the coach at Brussels, Brussels South (Gare du Midi), located 2 away from the city centre.
A trip to Brussels from Lyon is worth doing but not as a day trip with a journey time of 9h 40m each way. Check with Omio app the best way to travel.
The cheapest month for a coach from Lyon to Brussels is April.
It's helpful to compare your options as there are 3 ways to travel between Lyon and Brussels including taking a train, bus, and flight.
Yes, the following accessibility options are available when taking the coach from Lyon to Brussels:
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- TGV INOUI
- Wheelchair spaces, accessible toilets, boarding assistance available
Yes, there are bathrooms on board the coach from Lyon to Brussels for coach company BlaBlaCar Bus, FlixBus, TGV INOUI.
Whether you can cancel your coach ticket from Lyon to Brussels depends on the coach companies:
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- TGV INOUI
- Refund conditions depend on ticket type
Yes, bikes are allowed on board the coach with coach company BlaBlaCar Bus, FlixBus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the coach from Lyon to Brussels.
Yes, the following luggage options are included when booking a coach ticket from Lyon to Brussels:
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- TGV INOUI
- 1 hand luggage + 2 pieces of luggage free of charge
Yes, the following additional luggage options are available when booking a coach ticket from Lyon to Brussels:
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the coach from Lyon to Brussels. The following conditions apply:
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- TGV INOUI
- Small pets in carriers: Free. Large dogs: Paid ticket required. Guide dogs: Free
You can reserve your seat on the coach from Lyon to Brussels with the following coach company: BlaBlaCar Bus, FlixBus, TGV INOUI
Yes, there are USB plugs on board the coach from Lyon to Brussels with the following coach company: BlaBlaCar Bus, FlixBus, TGV INOUI.
Yes, there is Wifi on board the coach from Lyon to Brussels with the following coach company: BlaBlaCar Bus, FlixBus, TGV INOUI.
popular bus stations
Popular bus stations from Lyon to Brussels
Lyon
Brussels
The major bus station for departures in Lyon is Lyon, Gare Routière de Perrache. Find all the information you need to know about services, amenities and connections at Lyon, Gare Routière de Perrache for your trip from Lyon to Brussels.
Lyon, Gare Routière de Perrache
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
1 km
Car connection
Cours de VerdunWifi
- Free Wi-Fi
Dining
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Lyon, Gare Routière de Perrache
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
Lyon, St Exupéry Aéroport
information
Lyon, Gare Perrache
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
1 kmCar connection
Cours de Verdun RambaudWifi
- Free Wi-Fi
Dining
- Café de la Gare (in the station)
- Bistro Lyonnais (0.2 km)
- Fast Food Express (0.3 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available on the concourse.
Public transit options for Lyon, Gare Perrache
- Bus: C21, C22, S1 Metro: A Train: TER
The major bus station for arrivals in Brussels is Brussels, Brussels South (Gare du Midi). Find all the information you need to know about services, amenities and connections at Brussels, Brussels South (Gare du Midi) for your trip to Brussels from Lyon.
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:00
Distance to city center
2 kmCar connection
Avenue FonsnyWifi
- Free Wi-Fi
Dining
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Brussels, Brussels South (Gare du Midi)
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
Amenities at bus station
WifiParkingDiningATMTaxisAccessibilityWCTicket Officeinformation
Ticket Office Hours
- 06:00-23:59
Distance to city center
1 kmCar connection
Rue du ProgrèsWifi
- Free Wi-Fi
Dining
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
Taxis
- Available outside the main entrance.
Accessibility
- Elevators, ramps
WC
- Available in the station.
Public transit options for Brussels-Noord
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
Brussels, Gare Du Midi
information
Most popular bus connections from Lyon
More options for your journey from Lyon to Brussels
Here are some other resources that might have the information you need
Most popular buses to and from Brussels and Lyon
Most popular bus connections to Brussels
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