4.9
4.6The cheapest and fastest buses from Lyon to Brussels
Cheapest price
€43
Average price
€50
Fastest journey
10 h 45 m
Average duration
11 h 17 m
Buses per day
8
Distance
569 km
The best way to find a cheap bus ticket from Lyon to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Lyon to Brussels will cost around €50 if you buy it on the day, but the cheapest tickets can be found for only €43.
Of the 8 buses that leave Lyon for Brussels on Sat, Nov 22, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Nov 22 the direct buses cover the 569 km distance in an average of 11 h 17 m but if you time it right, some buses will get you there in just 10 h 45 m .
On Sat, Nov 22 the slowest buses will take 11 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus
58074 · 50337FlixBus · FlixBusFlixBus · FlixBusFlixBus · FlixBusFlixBus5808 · 1657FlixBus · FlixBus58074 · 50337FlixBus · FlixBus
Travel Information
Compare train, bus, and flight for Lyon to Brussels
Omio recommends booking the train as it is the most popular option from Lyon to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €21. For those with little time consider booking a flight which can get you there in 1h 59m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of €21, and a flight costs an average of €158.
Distance: 569 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€56 Average price Cheapest | €130 Average price | €286 Average price |
9h 52m Average total duration 9h 22m Onboard + 30m Additional time* | 4h 21m Average total duration 3h 51m Onboard + 30m Additional time* | 4h 59m Average total duration Fastest 1h 59m Onboard + 3h 0m Additional time* |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.4kg CO2 emissions |
Most popular bus company |  Most popular train company |  Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Lyon to Brussels bus times
The table below shows live departures for Lyon to Brussels buses for today, Friday, November 21. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 12:45 AM Lyon, Perrache Bus Station | 11h55 | 12:40 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus | 12:45 AM Lyon, Perrache Bus Station | 14h05 | 2:50 PM Brussels, Gare Du Midi | 1 transfer | |
| FlixBus · FlixBus | 3:00 AM Lyon, Perrache Bus Station | 11h35 | 2:35 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus | 4:25 AM Lyon, Perrache Bus Station | 12h30 | 4:55 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus | 7:40 AM Lyon, Perrache Bus Station | 12h10 | 7:50 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus · FlixBus | 9:10 AM Lyon, Perrache Bus Station | 13h20 | 10:30 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| 58074 · 50337 | 11:00 AM Lyon, Perrache Bus Station | 11h35 | 10:35 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| FlixBus | 8:30 PM Lyon, Perrache Bus Station | 10h45 | 7:15 AM Brussels, Brussels South (Gare du Midi) | 0 transfersDirect | |
| FlixBus · FlixBus | 11:50 PM Lyon, Perrache Bus Station | 11h30 | 11:20 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
| Saturday, November 22 | |||||
| 5808 · 1657 | 12:00 AM Lyon, Perrache Bus Station | 11h00 | 11:00 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Lyon to Brussels by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 22
Nov 23
Nov 24
Nov 25
Nov 26
Nov 27
Nov 28
Nov 29
Nov 30
Dec 01
Dec 02
Dec 03
Dec 04
Dec 05
Dec 06
Dec 07
Dec 08
Dec 09
Dec 10
Dec 11
Dec 12
Journey information
Overview: Bus from Lyon to Brussels
France
Belgium
Buses from Lyon to Brussels run on average 18 times per day, taking around 9h 22m. Cheap bus tickets for this journey start at €21 if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 569 km distance in 9h 40m.
Distance 569 km |
Average bus duration 9h 22m |
Cheapest ticket price €21 |
Buses per day 18 |
Direct buses 3 |
Fastest bus 9h 40m |
First bus 00:05 |
Last bus 23:55 |
Bus providers: BlaBlaCar Bus, FlixBus, BlaBlaCar from Lyon to BrusselsYou can travel by bus between Lyon to Brussels with BlaBlaCar Bus, FlixBus, BlaBlaCar for as low as €21. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
BlaBlaCar
FAQs: Bus from Lyon to Brussels
Find answers to the most common questions about traveling from Lyon to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.
When departing from Lyon, you have various coach station options to start your route from including Lyon, Perrache Bus Station and Lyon, Gare Perrache. When arriving in Brussels, you can end your route in coach stations like Bruxelles, Gare du Nord and Brussels, Brussels South (Gare du Midi).
Passengers board the coach most frequently from Lyon, Perrache Bus Station, which is located around 1.4 miles (2.3 km) away from the city centre, and they get off the coach at Bruxelles, Gare du Nord, located 1.1 miles (1.7 km) away from the city centre.
To find the cheapest bus tickets for your trip from Lyon to Brussels, follow these tips:
Start your search now and compare ticket prices to find the best deal!
popular bus stations
Popular bus stations from Lyon to Brussels
WifiParkingDiningATMTaxisAccessibilityWCTicket Office
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Bistro Lyonnais (0.2 km)
- Fast Food Express (0.3 km).
- Available outside the main entrance.
- Elevators, ramps
- Available on the concourse.
- Bus: C21, C22, S1 Metro: A Train: TER
WifiParkingDiningATMTaxisAccessibilityWCTicket Office- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
WifiParkingDiningATMTaxisAccessibilityWCTicket Office- 06:00-23:59
- Free Wi-Fi
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
WifiParkingDiningATMTaxisAccessibilityWCTicket Office- 06:00-23:00
- Free Wi-Fi
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
WifiParkingATMTaxisAccessibilityWCTicket Office- 06:00-23:00
- Free Wi-Fi
- Available outside the main terminal.
- Elevators, ramps
- Available in the station.
- Bus: 272, 471 Train: IC, S2, S4
Most popular bus connections from Lyon
More options for your journey from Lyon to Brussels
Here are some other resources that might have the information you need
Most popular buses to and from Brussels and Lyon
Most popular bus connections to Brussels
The Omio App Makes Travel Planning Easy
We’ll get you where you want to go. From live train updates to mobile tickets, our innovative app is the ideal way to plan and keep track of your travel.
