The cheapest and fastest buses from Madrid to Brussels
Cheapest price on Sep 23
€40
Average ticket price on Sep 23
€68
Fastest journey on Sep 23
20 h 30 m
Average journey duration on Sep 23
21 h 8 m
Buses on Sep 23
11
Distance
1316 km
The best way to find a cheap bus ticket from Madrid to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Madrid to Brussels will cost around €68 if you buy it on the day, but the cheapest tickets can be found for only €40.
It's difficult to get from Madrid to Brussels without transferring at least once.
3162 · 503216:35 PM20h40Madrid, Estación Sur de Autobuses3:15 PMBrussels, Brussels South (Gare du Midi)€401One-way1 transfer
3160 · 5010010:30 PM22h20Madrid, Estación Sur de Autobuses8:50 PMBrussels, Brussels South (Gare du Midi)€421One-way1 transfer
4004 · 16573:30 PM20h30Madrid, Estación Sur de Autobuses12:00 PMBrussels, Brussels South (Gare du Midi)€551One-way1 transfer
Normal · Normal3:30 PM22h40Madrid, Estación Sur de Autobuses2:10 PMBruxelles, Rue de France (Brussel-Zuid/Midi)€551One-way1 transfer
Normal · Normal3:30 PM22h40Madrid, Estación Sur de Autobuses2:10 PMBruxelles, Rue de France (Brussel-Zuid/Midi)€551One-way1 transfer
4004 · 16573:30 PM20h30Madrid, Estación Sur de Autobuses12:00 PMBrussels, Brussels South (Gare du Midi)€551One-way1 transfer
3162 · 503216:35 PM20h40Madrid, Estación Sur de Autobuses3:15 PMBrussels, Brussels South (Gare du Midi)€401One-way1 transfer
FlixBus · FlixBus8:50 PM21h05Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid)5:55 PMBrussels, Brussels South (Gare du Midi)€891One-way1 transfer
FlixBus · FlixBus8:25 PM21h30Madrid, Estación Sur de Autobuses5:55 PMBrussels, Brussels South (Gare du Midi)€891One-way1 transfer
FlixBus · FlixBus2:50 PM21h55Madrid, Estación Sur de Autobuses12:45 PMBrussels, Brussels South (Gare du Midi)€851One-way1 transfer
Travel Information
Compare bus, train, and flight for Madrid to Brussels
Omio recommends booking the flight as it is the most popular option from Madrid to Brussels among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €89 For those with little time, consider booking a flight, which has an average total journey time of 6h 38m. If you are seeking to minimise your carbon footprint, the bus is your best option, with estimated CO2 emissions of 1.3 - 3.3kg. Average ticket prices depend on the travel mode: a bus costs an average of €89, while a flight costs an average of €404.
Distance: 1316 km
Compare bus with
| Bus | Most popular Flight | Driving |
|---|---|---|
€89 Average price Cheapest | €404 Average price | €258 Average price (fuel + tolls) |
21h 42m Average total duration 21h 12m Onboard + 30m Additional time* | 6h 38m Average total duration Fastest 4h 38m Onboard + 2h 0m Additional time* | 16h 17m Average total duration (door-to-door) |
1.3 - 3.3kg CO2 emissions Lowest | 3.9 - 7.9kg CO2 emissions | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Madrid to Brussels:
A bus is €315 less than a flight for this route with tickets for a flight from Madrid to Brussels costing on average €404.
Other travel options to Brussels take longer:
Bus takes on average 21h 12m.
Live departures
Madrid to Brussels bus times
The table below shows live departures for Madrid to Brussels buses for today, Tuesday, September 22. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 2:50 PM Madrid, Estación Sur de Autobuses | 21h55 | 12:45 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
4004 · 1657 | 3:30 PM Madrid, Estación Sur de Autobuses | 20h30 | 12:00 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:55 PM Madrid, Estación Sur de Autobuses | 23h40 | 3:35 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus | 3:55 PM Madrid, Estación Sur de Autobuses | 23h55 | 3:50 PM Brussels, Gare Du Midi | 1 transfer | |
FlixBus · FlixBus · FlixBus | 3:55 PM Madrid, Estación Sur de Autobuses | 26h00 | 5:55 PM Brussels, Brussels South (Gare du Midi) | 2 transfers | |
FlixBus · FlixBus | 4:40 PM Madrid, Estación Sur de Autobuses | 23h10 | 3:50 PM Brussels, Gare Du Midi | 1 transfer | |
FlixBus · FlixBus | 4:40 PM Madrid, Estación Sur de Autobuses | 22h55 | 3:35 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
3162 · 1433 | 6:35 PM Madrid, Estación Sur de Autobuses | 22h55 | 5:30 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 8:25 PM Madrid, Estación Sur de Autobuses | 21h30 | 5:55 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 8:50 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 21h05 | 5:55 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
3160 · 50100 | 10:30 PM Madrid, Estación Sur de Autobuses | 22h20 | 8:50 PM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 10:35 PM Madrid, Estación Sur de Autobuses | 26h35 | 1:10 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
FlixBus · FlixBus | 10:55 PM Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) | 26h15 | 1:10 AM Brussels, Brussels South (Gare du Midi) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Madrid to Brussels by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Sep 22
Sep 23
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Sep 27
Sep 28
Sep 29
Sep 30
Oct 01
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Oct 12
Why should you book Madrid to Brussels buses with Omio?
Why book with Omio vs Alsa?
- Compare with other providers: On Omio, you can not only buy tickets for Alsa, but also compare tickets for the likes of Infobus, BlaBlaCar Bus, Internorte or FlixBus to find the best option for your trip from Madrid to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Alsa with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Madrid to Brussels.
Why book with Omio over Checkmybus, Rome2rio or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Infobus, BlaBlaCar Bus, Internorte or FlixBus to find the best option for your trip from Madrid to Brussels.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Madrid to Brussels.
Journey information
Overview: Bus from Madrid to Brussels
Buses from Madrid to Brussels run on average 11 times per day, taking around 21h 12m. Cheap bus tickets for this journey start at €14 if you book in advance.
The earliest bus runs at 00:40, the last at 23:55. The fastest bus covers the 1316 km distance in 18h 25m.
Distance 1316 km |
Average bus duration 21h 12m |
Cheapest ticket price €14 |
Buses per day 11 |
Fastest bus 18h 25m |
First bus 12:40 AM |
Last bus 11:55 PM |
Cheapest Month Feb |
Cheapest Day Sun |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Mon |
Best time to book 84 days |
Bus providers: FlixBus, BlaBlaCar Bus, Infobus, Alsa, Internorte from Madrid to BrusselsYou can travel by bus between Madrid to Brussels with FlixBus, BlaBlaCar Bus, Infobus, Alsa, Internorte for as low as €14. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
Alsa
BlaBlaCar Bus
Internorte
FAQs: Bus from Madrid to Brussels
Find answers to the most common questions about traveling from Madrid to Brussels by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

- Alsa
- Assistance
- Priority boarding
- Accessible seating.
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- Alsa
- You can cancel your ticket up to 48 hours before departure for a partial refund. Changes allowed for a fee.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- Alsa
- One carry-on bag up to 10kg and one checked bag up to 25kg.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- Alsa
- Additional luggage can be purchased for a fee.
- Infobus
- 10€ per additional bag.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- Alsa
- Small pets allowed in carriers
- larger pets must travel in the hold.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Madrid to Brussels
Most Madrid to Brussels buses use the Madrid, Estación Sur de Autobuses to Brussels, Brussels South (Gare du Midi) station pair, with some services arriving at Schaerbeek, Bd Roi Albert II (Bruxelles Gare Du Nord). Use this guide to compare Madrid and Brussels bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Madrid station do buses to Brussels leave from?
Getting to Madrid, Estación Sur de Autobuses from Madrid city centre
Madrid, Estación Sur de Autobuses is 3 km from Madrid city centre. Public transport options include:
Madrid, Estación Sur de Autobuses bus station facilities and services
Madrid, Estación Sur de Autobuses has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafetería de la estación (in the station), Restaurante El Brillante (0.5 km), La Taberna de Domínguez (0.7 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Tickets and information
Ticket office support is available at Madrid, Estación Sur de Autobuses.
Parking, taxis and toilets
Available at Madrid, Estación Sur de Autobuses: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Madrid, Estación Sur de Autobuses: Elevators, ramps.
Getting to Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) from Madrid city centre
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) is 12 km from Madrid city centre. Public transport options include:
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) bus station facilities and services
Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid) has practical services for this route, including Dining, ATM, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Rodilla, Mahoudrid
Wi-Fi and ATMs
ATMs are aTMs located throughout T4, major cards accepted .
Tickets and information
Ticket office support is available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid).
Parking, taxis and toilets
Available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): WC.
Accessibility
Accessibility facilities are available at Madrid, Terminal de autobuses T4 (Aeropuerto de Madrid): Step-free access, elevators, accessible toilets.
Getting to Madrid from Madrid city centre
Which Brussels station do buses from Madrid arrive at?
Getting to Brussels, Brussels South (Gare du Midi) from Brussels city centre
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) bus station facilities and services
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Tickets and information
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Parking, taxis and toilets
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Getting to Brussels, Gare Du Midi from Brussels city centre
Brussels, Gare Du Midi is 1 km from Brussels city centre. Public transport options include:
Brussels, Gare Du Midi bus station facilities and services
Brussels, Gare Du Midi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Various dining options are nearby.
Wi-Fi and ATMs
Wi-Fi is available at Brussels, Gare Du Midi. ATMs are available at Brussels, Gare Du Midi.
Tickets and information
Ticket office support is available at Brussels, Gare Du Midi.
Parking, taxis and toilets
Available at Brussels, Gare Du Midi: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussels, Gare Du Midi: Station is accessible for individuals with disabilities.
Getting to Brussel, Avenue des Magnolias (Koning Boudewijn) from Brussels city centre
Brussel, Avenue des Magnolias (Koning Boudewijn) is 5 km from Brussels city centre. Public transport options include:
Brussel, Avenue des Magnolias (Koning Boudewijn) bus station facilities and services
Brussel, Avenue des Magnolias (Koning Boudewijn) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Brussel, Avenue des Magnolias (Koning Boudewijn). ATMs are available at Brussel, Avenue des Magnolias (Koning Boudewijn).
Tickets and information
Ticket office support is available at Brussel, Avenue des Magnolias (Koning Boudewijn).
Parking, taxis and toilets
Available at Brussel, Avenue des Magnolias (Koning Boudewijn): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussel, Avenue des Magnolias (Koning Boudewijn): Accessible for people with reduced mobility.
More options for your journey from Madrid to Brussels
Here are some other resources that might have the information you need

