Travel Information
Compare bus, train, and flight for Madrid to Brussels
Omio recommends booking the flight as it is the most popular option from Madrid to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €46. For those with little time consider booking a flight which can get you there in 4h 4m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.3 - 3.3kg. The ticket price range depends on the travel mode: a bus costs an average of €46, and a train costs an average of €406.
Distance: 1316 km
Compare flight with
Most popular Flight | Bus | Train |
|---|---|---|
€226 Average price | €84 Average price Cheapest | €411 Average price |
7h 4m Average total duration Fastest 4h 4m Onboard + 3h 0m Additional time* | 18h 8m Average total duration 17h 38m Onboard + 30m Additional time* | 21h 13m Average total duration 20h 43m Onboard + 30m Additional time* |
3.9 - 7.9kg CO2 emissions | 1.3 - 3.3kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular airline | ![]() Most popular bus company | |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Madrid to Brussels
How to get from Madrid to Brussels by train, bus or flight.
Our recommendation
The best way to travel from Madrid to Brussels is by taking a bus because it’s the best combination of price and speed.
FlixBus · FlixBus3:55 PM23h55Madrid, Estación Sur de Autobuses3:50 PMBrussels, Gare Du Midi€1101One-way1 transfer
Cheapest
FlixBus · FlixBus3:55 PM23h55Madrid, Estación Sur de Autobuses3:50 PMBrussels, Gare Du Midi€1101One-way1 transfer
Fastest
SN372212:40 PM2h15Madrid Barajas Airport2:55 PMBrussels Airport€3331One-way0 transfers
Other options
FlixBus · FlixBus · FlixBus3:55 PM25h20Madrid, Estación Sur de Autobuses5:15 PMBrussels, Brussels South (Gare du Midi)€1111One-way2 transfers
FlixBus · FlixBus · FlixBus · FlixBus3:55 PM30h15Madrid, Estación Sur de Autobuses10:10 PMBrussels, Avenue des Magnolias (King Baudouin)€1141One-way3 transfers
FlixBus · FlixBus · FlixBus3:55 PM23h40Madrid, Estación Sur de Autobuses3:35 PMBrussels, Brussels South (Gare du Midi)€1231One-way2 transfers
IB6038:10 PM2h20Madrid Barajas Airport10:30 PMBrussels Airport€1901One-way0 transfers
IB6014:35 PM2h25Madrid Barajas Airport7:00 PMBrussels Airport€1901One-way0 transfers
UX11733:15 PM2h25Madrid Barajas Airport5:40 PMBrussels Airport€2171One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jun 25
Jun 26
Jun 27
Jun 28
Jun 29
Jun 30
Jul 01
Jul 02
Jul 03
Jul 04
Jul 05
Jul 06
Jul 07
Jul 08
Jul 09
Jul 10
Jul 11
Jul 12
Jul 13
Jul 14
Jul 15
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Madrid to Brussels
Travel to Brussels easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Madrid to Brussels.

This is compared to other travel options from Madrid to Brussels:
A bus is €143 less than a flight for this route with tickets for a flight from Madrid to Brussels costing on average €226.
A bus is €327 less than a train for this route with tickets for a train from Madrid to Brussels costing on average €411.
Other travel options to Brussels take longer:
Bus takes on average 17h 38m.
Train takes on average 20h 43m.
- Around 40 flights per day.
- Around 10 buses per day.
- Around 2 trains per day.
However, we recommend checking specific travel dates for your route between Madrid and Brussels as scheduled services by bus, train, and flight can vary by season or day of the week.
- Flights mostly depart from Madrid Barajas Airport and arrive in Brussels Airport.
- Buses mostly depart from Madrid, Estación Sur de Autobuses and arrive in Brussels, Brussels South (Gare du Midi).
- Travel with Ryanair, Iberia, Brussels Airlines, Air Europa, Vueling, TAP Portugal, KLM, Lufthansa, Iberojet, Alba Star, Air Nostrum, Air Baltic, Pascan Aviation, ITA, British Airways, Lufthansa City Airlines to go to Brussels by flight.
- Travel with AVE, Renfe Viajeros to go to Brussels by train.
- Travel with BlaBlaCar Bus, FlixBus, Infobus, Alsa to go to Brussels by bus.
- 10 direct flights per day with Ryanair, Iberia, Brussels Airlines, Air Europa, Iberojet, Alba Star, Air Nostrum, Air Baltic.
Travelling from Madrid to Brussels: related information
Here are some other resources that might have the information you need


