The cheapest and fastest trains from Madrid to Brussels
Cheapest price
€406
Average price
€411
Fastest journey
18 h 54 m
Average duration
20 h 17 m
Trains per day
2
Distance
1316 km
The best way to find a cheap train ticket from Madrid to Brussels is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Madrid to Brussels will cost around €411 if you buy it on the day, but the cheapest tickets can be found for only €406.
It's difficult to get from Madrid to Brussels without transferring at least 3 times.
12:50 PM18h54Madrid7:44 AMBrussels€4061One-way3 transfers
9:07 PM21h40Madrid6:47 PMBrussels€4161One-way3 transfers
12:50 PM18h54Madrid7:44 AMBrussels€4061One-way3 transfers
9:07 PM21h40Madrid6:47 PMBrussels€4161One-way3 transfers
Travel Information
Compare bus, train, and flight for Madrid to Brussels
Omio recommends booking the flight as it is the most popular option from Madrid to Brussels among Omio's users. If you are prioritising price take the bus with prices starting from €46. For those with little time consider booking a flight which can get you there in 4h 4m. In case you are seeking to minimise your carbon footprint the bus is your best bet as it emits only 1.3 - 3.3kg. The ticket price range depends on the travel mode: a bus costs an average of €46, and a train costs an average of €406.
Distance: 1316 km
Compare train with
| Train | Most popular Flight | Bus |
|---|---|---|
€411 Average price | €226 Average price | €84 Average price Cheapest |
21h 13m Average total duration 20h 43m Onboard + 30m Additional time* | 7h 4m Average total duration Fastest 4h 4m Onboard + 3h 0m Additional time* | 18h 8m Average total duration 17h 38m Onboard + 30m Additional time* |
- CO2 emissions | 3.9 - 7.9kg CO2 emissions | 1.3 - 3.3kg CO2 emissions Lowest |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Compare prices and tickets Madrid to Brussels by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Madrid to Brussels trains with Omio?
Why book with Omio vs AVE?
- Compare with other providers: On Omio, you can not only buy tickets for AVE, but also compare tickets for the likes of Renfe Viajeros to find the best option for your trip from Madrid to Brussels.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare AVE with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Madrid to Brussels.
Why book with Omio over Rome2rio, Raileurope or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Madrid to Brussels.
How far in advance should I book train tickets from Madrid to Brussels?
Journey information
Overview: Train from Madrid to Brussels
Trains from Madrid to Brussels run on average 2 times per day, taking around 20h 43m. Cheap train tickets for this journey start at €406 but you can travel from only €46 by bus.
The earliest train runs at 05:50, the last at 17:20. The fastest train covers the 1316 km distance in 18h 54m.
Distance 1316 km |
Average train duration 20h 43m |
Cheapest ticket price €406 |
Trains per day 2 |
Fastest train 18h 54m |
First train 5:50 AM |
Last train 5:20 PM |
High Season Oct - Dec |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 35 days |
Train companies: AVE, Renfe Viajeros from Madrid to Brussels trainsAVE, Renfe Viajeros trains will get you between Madrid and Brussels from €46. With over 1000 travel companies on Omio, you can find the best train times and tickets for your trip.
AVE
Renfe Viajeros
FAQs: Trains from Madrid to Brussels
Find answers to the most common questions about traveling from Madrid to Brussels by train. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest train, the cheapest option, or tips for making the most of your visit at Brussels, this guide helps you travel smarter and with confidence.

Most popular train connections from Madrid
More options for your journey from Madrid to Brussels
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