The cheapest and fastest buses from Milan to Lyon
Cheapest price
€17
Average price
€29
Fastest journey
5 h 10 m
Average duration
6 h 3 m
Buses per day
18
Distance
339 km
The best way to find a cheap bus ticket from Milan to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Milan to Lyon will cost around €29 if you buy it on the day, but the cheapest tickets can be found for only €17.
Of the 18 buses that leave Milan for Lyon on Wed, Nov 19, 13 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Nov 19 the direct buses cover the 339 km distance in an average of 6 h 3 m but if you time it right, some buses will get you there in just 5 h 10 m .
On Wed, Nov 19 the slowest buses will take 6 h 25 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
51065
FlixBus
FlixBus
FlixBus
3492
FlixBus
FlixBus
FlixBus
FlixBusTravel Information
Compare train, bus, and flight for Milan to Lyon
Omio recommends booking the bus as it is the most popular option from Milan to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €15. For those with little time consider booking a flight which can get you there in 2h 42m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.3kg. The ticket price range depends on the travel mode: a bus costs an average of €15, and a flight costs an average of €93.
Distance: 339 km
Compare bus with
Most popular Bus | Train | Flight |
|---|---|---|
€36 Average price Cheapest | €116 Average price | €222 Average price |
7h 12m Average total duration 6h 42m Onboard + 30m Additional time* | 6h 1m Average total duration 5h 31m Onboard + 30m Additional time* | 5h 42m Average total duration Fastest 2h 42m Onboard + 3h 0m Additional time* |
0.3 - 0.8kg CO2 emissions | 0.1 - 0.3kg CO2 emissions Lowest | 1.0 - 2.0kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Milan to Lyon bus times
The table below shows live departures for Milan to Lyon buses for today, Tuesday, November 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 4:45 AM Milano, Autostazione Lampugnano | 6h15 | 11:00 AM Lyon, Perrache Bus Station | 0 transfersDirect | |
2499 · 3492 | 5:00 AM Milano, Autostazione Lampugnano | 15h30 | 8:30 PM Lyon, Perrache Bus Station | 1 transfer | |
0 | 5:20 AM Milano | 6h35 | 11:55 AM Lyon, Gare Perrache | 0 transfersDirect | |
3898 | 5:20 AM Milano, Autostazione Lampugnano | 6h35 | 11:55 AM Lyon, Perrache Bus Station | 0 transfersDirect | |
2499 · 3492 | 5:50 AM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 14h40 | 8:30 PM Lyon, Perrache Bus Station | 1 transfer | |
FlixBus | 6:25 AM Milano, Autostazione Lampugnano | 6h50 | 1:15 PM Lyon, Perrache Bus Station | 0 transfersDirect | |
FlixBus | 7:30 AM Milano, Autostazione Lampugnano | 6h40 | 2:10 PM Lyon, Perrache Bus Station | 0 transfersDirect | |
FlixBus | 8:05 AM Milano, Autostazione Lampugnano | 7h10 | 3:15 PM Lyon, Perrache Bus Station | 0 transfersDirect | |
3492 | 1:55 PM Milano, Autostazione Lampugnano | 6h35 | 8:30 PM Lyon, Perrache Bus Station | 0 transfersDirect | |
0 | 1:55 PM Milano | 6h35 | 8:30 PM Lyon, Gare Perrache | 0 transfersDirect | |
FlixBus | 2:00 PM Milano, Autostazione Lampugnano | 6h15 | 8:15 PM Lyon, Perrache Bus Station | 0 transfersDirect | |
FlixBus | 5:00 PM Milano, Autostazione Lampugnano | 6h35 | 11:35 PM Lyon, Perrache Bus Station | 0 transfersDirect | |
2421 · 3898 | 8:35 PM Milano, San Donato - Settore B (Viale Giuseppe Impastato) | 15h20 | 11:55 AM Lyon, Perrache Bus Station | 1 transfer | |
FlixBus | 8:45 PM Milano, Autostazione Lampugnano | 6h10 | 2:55 AM Lyon, Perrache Bus Station | 0 transfersDirect | |
FlixBus | 9:50 PM Milano, Autostazione Lampugnano | 6h25 | 4:15 AM Lyon, Perrache Bus Station | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Milan to Lyon by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 18
Nov 19
Nov 20
Nov 21
Nov 22
Nov 23
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Nov 25
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Journey information
Overview: Bus from Milan to Lyon
Buses from Milan to Lyon run on average 20 times per day, taking around 6h 42m. Cheap bus tickets for this journey start at €15 if you book in advance.
There are 15 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 339 km distance in 6h 15m.
Distance 339 km |
Average bus duration 6h 42m |
Cheapest ticket price €15 |
Buses per day 20 |
Direct buses 15 |
Fastest bus 6h 15m |
First bus 00:05 |
Last bus 23:55 |
Bus providers: BlaBlaCar Bus, FlixBus, Ourbus, BlaBlaCar, Itabus from Milan to LyonYou can travel by bus between Milan to Lyon with BlaBlaCar Bus, FlixBus, Ourbus, BlaBlaCar, Itabus for as low as €15. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Itabus
BlaBlaCar Bus
Ourbus
BlaBlaCar
FAQs: Bus from Milan to Lyon
Find answers to the most common questions about traveling from Milan to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

When departing from Milan, you have various coach station options to start your trip from including Orio al Serio, Milan Bergamo Airport (Bus station), Milan, Lampugnano (M1) and Milano, Autostazione Lampugnano. When arriving in Lyon, you can end your journey in coach stations like Lyon, Perrache Bus Station and Lyon, Gare Perrache.
Passengers board the coach most frequently from Orio al Serio, Milan Bergamo Airport (Bus station), which is located around 28.2 miles (45.5 km) away from the city centre, and they get off the coach at Lyon, Perrache Bus Station, located 1.4 miles (2.3 km) away from the city centre.
To find the cheapest bus tickets for your trip from Milan to Lyon, follow these tips:
Start your search now and compare ticket prices to find the best deal!
popular bus stations
Popular bus stations from Milan to Lyon
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Milano (in the station)
- Trattoria San Donato (0.5 km)
- Burger House (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M3 Bus: 121, 132, 133
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Lampugnano (in the station)
- Trattoria Milano (0.5 km)
- Pizza Express (0.7 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Metro: M1 Bus: 68, 78, 80
- 06:00-22:00
- Free Wi-Fi
- Cafeteria Italiana (in the station)
- Fast Food Express (in the station)
- Trattoria Milano (0.5 km).
- Available outside the station.
- Elevators, ramps
- Available in the station.
- Bus: 121, 132 Metro: M3
- The place has an entrance that is wheelchair-accessible
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Bistro Lyonnais (0.2 km)
- Fast Food Express (0.3 km).
- Available outside the main entrance.
- Elevators, ramps
- Available on the concourse.
- Bus: C21, C22, S1 Metro: A Train: TER
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
Most popular bus connections from Milan
More options for your journey from Milan to Lyon
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