The cheapest and fastest buses from Brussels to Lyon
Cheapest price on Sep 29
€20
Average ticket price on Sep 29
€26
Fastest journey on Sep 29
10 h 15 m
Average journey duration on Sep 29
11 h 32 m
Buses on Sep 29
6
Distance
569 km
The best way to find a cheap bus ticket from Brussels to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brussels to Lyon will cost around €26 if you buy it on the day, but the cheapest tickets can be found for only €20.
On Tue, Sep 29, we found 6 buses from Brussels to Lyon, including 1 direct services.
On Tue, Sep 29 the direct buses cover the 569 km distance in an average of 11 h 32 m but if you time it right, some buses will get you there in just 10 h 15 m .
On Tue, Sep 29 the slowest buses will take 13 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1408 · 58075:55 PM10h35Brussels, Brussels South (Gare du Midi)4:30 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€201One-way1 transfer
50338 · 51337:05 PM10h15Brussels, Brussels South (Gare du Midi)5:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€201One-way1 transfer
FlixBus · FlixBus10:05 AM13h45Brussels, Gare Du Midi11:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€271One-way1 transfer
FlixBus · FlixBus1:40 PM13h30Brussels, Brussels South (Gare du Midi)3:10 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€271One-way1 transfer
FlixBus · FlixBus11:05 AM12h45Brussels, Brussels South (Gare du Midi)11:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€271One-way1 transfer
50338 · 51337:05 PM10h15Brussels, Brussels South (Gare du Midi)5:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€201One-way1 transfer
1408 · 58075:55 PM10h35Brussels, Brussels South (Gare du Midi)4:30 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€201One-way1 transfer
FlixBus8:15 PM10h35Brussels, Brussels South (Gare du Midi)6:50 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€321One-way0 transfers
FlixBus · FlixBus11:05 AM12h45Brussels, Brussels South (Gare du Midi)11:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€271One-way1 transfer
FlixBus · FlixBus1:40 PM13h30Brussels, Brussels South (Gare du Midi)3:10 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€271One-way1 transfer
Live departures
Brussels to Lyon bus times
The table below shows live departures for Brussels to Lyon buses for today, Monday, September 28. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 11:05 AM Brussels, Brussels South (Gare du Midi) | 12h45 | 11:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
50324 · 50107 | 11:30 AM Brussels, Brussels South (Gare du Midi) | 12h50 | 12:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 1:40 PM Brussels, Brussels South (Gare du Midi) | 13h30 | 3:10 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 2:05 PM Brussels, Brussels South (Gare du Midi) | 14h45 | 4:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 2 transfers | |
FlixBus · FlixBus | 4:40 PM Brussels, Brussels South (Gare du Midi) | 12h40 | 5:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
1408 · 83133 | 5:55 PM Brussels, Brussels South (Gare du Midi) | 10h10 | 4:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
50338 · 5133 | 7:05 PM Brussels, Brussels South (Gare du Midi) | 10h15 | 5:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 8:15 PM Brussels, Brussels South (Gare du Midi) | 10h35 | 6:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Brussels to Lyon by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Brussels to Lyon buses with Omio?
Why book with Omio vs Infobus?
- Compare with other providers: On Omio, you can not only buy tickets for Infobus, but also compare tickets for the likes of BlaBlaCar Bus or FlixBus to find the best option for your trip from Brussels to Lyon.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Infobus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Brussels to Lyon.
Why book with Omio over Busbud or Checkmybus?
- Official reseller: Infobus tickets can only be bought on Omio or Infobus's website as Omio is the only official third party seller for Infobus tickets. Busbud or Checkmybus do not sell Infobus tickets as they are not official sellers.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Brussels to Lyon.
Journey information
Overview: Bus from Brussels to Lyon
Buses from Brussels to Lyon run on average 14 times per day, taking around 10h 1m. Cheap bus tickets for this journey start at €14 if you book in advance.
There are 1 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 569 km distance in 8h 30m.
Distance 569 km |
Average bus duration 10h 1m |
Cheapest ticket price €14 |
Buses per day 14 |
Direct buses 1 |
Fastest bus 8h 30m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Sep |
Cheapest Day Thu |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Thu |
Least Busy Day Sun |
Best time to book 77 days |
Bus providers: BlaBlaCar Bus, FlixBus, Infobus from Brussels to LyonYou can travel by bus between Brussels to Lyon with BlaBlaCar Bus, FlixBus, Infobus for as low as €14. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
BlaBlaCar Bus
FAQs: Bus from Brussels to Lyon
Find answers to the most common questions about traveling from Brussels to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- 10€ per additional bag.
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Brussels to Lyon
Most Brussels to Lyon buses use the Brussels, Brussels South (Gare du Midi) to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) station pair, with some services arriving at Lyon, Gare Routière de Perrache. Use this guide to compare Brussels and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Brussels station do buses to Lyon leave from?
Getting to Brussels, Brussels South (Gare du Midi) from Brussels city centre
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) bus station facilities and services
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Tickets and information
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Parking, taxis and toilets
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Getting to Brussels, Gare Du Midi from Brussels city centre
Brussels, Gare Du Midi is 1 km from Brussels city centre. Public transport options include:
Brussels, Gare Du Midi bus station facilities and services
Brussels, Gare Du Midi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Various dining options are nearby.
Wi-Fi and ATMs
Wi-Fi is available at Brussels, Gare Du Midi. ATMs are available at Brussels, Gare Du Midi.
Tickets and information
Ticket office support is available at Brussels, Gare Du Midi.
Parking, taxis and toilets
Available at Brussels, Gare Du Midi: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussels, Gare Du Midi: Station is accessible for individuals with disabilities.
Getting to Brussel, Avenue des Magnolias (Koning Boudewijn) from Brussels city centre
Brussel, Avenue des Magnolias (Koning Boudewijn) is 5 km from Brussels city centre. Public transport options include:
Brussel, Avenue des Magnolias (Koning Boudewijn) bus station facilities and services
Brussel, Avenue des Magnolias (Koning Boudewijn) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Brussel, Avenue des Magnolias (Koning Boudewijn). ATMs are available at Brussel, Avenue des Magnolias (Koning Boudewijn).
Tickets and information
Ticket office support is available at Brussel, Avenue des Magnolias (Koning Boudewijn).
Parking, taxis and toilets
Available at Brussel, Avenue des Magnolias (Koning Boudewijn): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussel, Avenue des Magnolias (Koning Boudewijn): Accessible for people with reduced mobility.
Which Lyon station do buses from Brussels arrive at?
Getting to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) from Lyon city centre
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) bus station facilities and services
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Tickets and information
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Parking, taxis and toilets
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Getting to Lyon, Gare Routière de Perrache from Lyon city centre
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache bus station facilities and services
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance.
Tickets and information
Ticket office support is available at Lyon, Gare Routière de Perrache.
Parking, taxis and toilets
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Getting to Lyon, St Exupéry Aéroport from Lyon city centre
Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:
Lyon, St Exupéry Aéroport bus station facilities and services
Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.
Tickets and information
Ticket office support is available at Lyon, St Exupéry Aéroport.
Parking, taxis and toilets
Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.
More options for your journey from Brussels to Lyon
Here are some other resources that might have the information you need
