The cheapest and fastest buses from Brussels to Lyon
Cheapest price
€49
Average price
€78
Fastest journey
10 h 10 m
Average duration
10 h 26 m
Buses per day
15
Distance
569 km
The best way to find a cheap bus ticket from Brussels to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brussels to Lyon will cost around €78 if you buy it on the day, but the cheapest tickets can be found for only €49.
Of the 15 buses that leave Brussels for Lyon on Sun, Nov 16, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Nov 16 the direct buses cover the 569 km distance in an average of 10 h 26 m but if you time it right, some buses will get you there in just 10 h 10 m .
On Sun, Nov 16 the slowest buses will take 10 h 40 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
50320 · 5131
1608 · 94765
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus
50338 · 5133
50338 · 4787
FlixBus
1408 · 5807
FlixBus · FlixBusTravel Information
Compare train, bus, and flight for Brussels to Lyon
Omio recommends booking the train as it is the most popular option from Brussels to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €19. For those with little time consider booking a flight which can get you there in 1h 58m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of €19, and a flight costs an average of €134.
Distance: 569 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€43 Average price Cheapest | €126 Average price | €315 Average price |
10h 2m Average total duration 9h 32m Onboard + 30m Additional time* | 4h 13m Average total duration 3h 43m Onboard + 30m Additional time* | 4h 58m Average total duration Fastest 1h 58m Onboard + 3h 0m Additional time* |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.4kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Brussels to Lyon bus times
The table below shows live departures for Brussels to Lyon buses for today, Saturday, November 15. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 9:05 AM Brussels, Gare Du Midi | 13h15 | 10:20 PM Lyon, Perrache Bus Station | 1 transfer | |
FlixBus · FlixBus | 10:40 AM Brussels, Brussels South (Gare du Midi) | 11h40 | 10:20 PM Lyon, Perrache Bus Station | 1 transfer | |
1646 · 50107 | 12:30 PM Brussels, Brussels South (Gare du Midi) | 10h45 | 11:15 PM Lyon, Perrache Bus Station | 1 transfer | |
FlixBus · FlixBus | 1:15 PM Brussels, Brussels South (Gare du Midi) | 10h55 | 12:10 AM Lyon, Perrache Bus Station | 1 transfer | |
FlixBus · FlixBus | 2:10 PM Brussels, Brussels South (Gare du Midi) | 10h45 | 12:55 AM Lyon, Perrache Bus Station | 1 transfer | |
FlixBus · FlixBus | 3:40 PM Brussels, Brussels South (Gare du Midi) | 10h40 | 2:20 AM Lyon, Perrache Bus Station | 1 transfer | |
50336 · 83133 | 3:55 PM Brussels, Brussels South (Gare du Midi) | 11h05 | 3:00 AM Lyon, Perrache Bus Station | 1 transfer | |
1408 · 5807 | 4:55 PM Brussels, Brussels South (Gare du Midi) | 10h35 | 3:30 AM Lyon, Perrache Bus Station | 1 transfer | |
50338 · 5133 | 6:05 PM Brussels, Brussels South (Gare du Midi) | 10h10 | 4:15 AM Lyon, Perrache Bus Station | 1 transfer | |
FlixBus | 7:15 PM Brussels, Brussels South (Gare du Midi) | 10h30 | 5:45 AM Lyon, Perrache Bus Station | 0 transfersDirect | |
FlixBus · FlixBus | 12:30 AM Brussels, Brussels South (Gare du Midi) | 13h15 | 1:45 PM Lyon, Perrache Bus Station | 1 transfer | |
1608 · 94765 | 2:11 AM Brussels, Brussels South (Gare du Midi) | 11h24 | 1:35 PM Lyon, Perrache Bus Station | 1 transfer | |
FlixBus · FlixBus | 3:15 AM Brussels, Brussels South (Gare du Midi) | 11h05 | 2:20 PM Lyon, Perrache Bus Station | 1 transfer | |
50320 · 5131 | 6:20 AM Brussels, Brussels South (Gare du Midi) | 11h25 | 5:45 PM Lyon, Perrache Bus Station | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Brussels to Lyon by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Nov 15
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Nov 21
Nov 22
Nov 23
Nov 24
Nov 25
Nov 26
Nov 27
Nov 28
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Nov 30
Dec 01
Dec 02
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Dec 05
Journey information
Overview: Bus from Brussels to Lyon
Buses from Brussels to Lyon run on average 20 times per day, taking around 9h 32m. Cheap bus tickets for this journey start at €19 if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 569 km distance in 9h 40m.
Distance 569 km |
Average bus duration 9h 32m |
Cheapest ticket price €19 |
Buses per day 20 |
Direct buses 3 |
Fastest bus 9h 40m |
First bus 00:05 |
Last bus 23:55 |
Bus providers: BlaBlaCar Bus, FlixBus, BlaBlaCar from Brussels to LyonYou can travel by bus between Brussels to Lyon with BlaBlaCar Bus, FlixBus, BlaBlaCar for as low as €19. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
BlaBlaCar
FAQs: Bus from Brussels to Lyon
Find answers to the most common questions about traveling from Brussels to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

When departing from Brussels, you have various coach station options to start your trip from including Brussels, Brussels South (Gare du Midi), Bruxelles, Gare du Nord and Brussels, Boulevard Pachéco (Congrès). When arriving in Lyon, you can end your trip in coach stations like Lyon, Perrache Bus Station, Lyon, Gare Perrache and Lyon, Aéroport Saint Exupéry.
Passengers board the coach most frequently from Brussels, Brussels South (Gare du Midi), which is located around 2.7 miles (4.3 km) away from the city centre, and they get off the coach at Lyon, Perrache Bus Station, located 1.2 miles (1.9 km) away from the city centre.
popular bus stations
Popular bus stations from Brussels to Lyon
- 06:00-23:59
- Free Wi-Fi
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
- 06:00-23:00
- Free Wi-Fi
- Available outside the main terminal.
- Elevators, ramps
- Available in the station.
- Bus: 272, 471 Train: IC, S2, S4
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Bistro Lyonnais (0.2 km)
- Fast Food Express (0.3 km).
- Available outside the main entrance.
- Elevators, ramps
- Available on the concourse.
- Bus: C21, C22, S1 Metro: A Train: TER
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
Most popular bus connections from Brussels
More options for your journey from Brussels to Lyon
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