The cheapest and fastest buses from Brussels to Lyon
Cheapest price
€41
Average price
€86
Fastest journey
7 h 30 m
Average duration
7 h 44 m
Buses per day
20
Distance
569 km
The best way to find a cheap bus ticket from Brussels to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brussels to Lyon will cost around €86 if you buy it on the day, but the cheapest tickets can be found for only €41.
Of the 20 buses that leave Brussels for Lyon on Sun, Feb 15, 7 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Feb 15 the direct buses cover the 569 km distance in an average of 7 h 44 m but if you time it right, some buses will get you there in just 7 h 30 m .
On Sun, Feb 15 the slowest buses will take 7 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.

50828
50320 · 5131
1646 · 50107




Travel Information
Compare train, bus, and flight for Brussels to Lyon
Omio recommends booking the train as it is the most popular option from Brussels to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €19. For those with little time consider booking a flight which can get you there in 2h 4m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of €19, and a flight costs an average of €112.
Distance: 569 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€40 Average price Cheapest | €125 Average price | €247 Average price |
10h 0m Average total duration 9h 30m Onboard + 30m Additional time* | 4h 14m Average total duration 3h 44m Onboard + 30m Additional time* | 5h 4m Average total duration Fastest 2h 4m Onboard + 3h 0m Additional time* |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.4kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Brussels to Lyon bus times
The table below shows live departures for Brussels to Lyon buses for today, Saturday, February 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
50324 · 94761 | 10:30 AM Brussels, Brussels South (Gare du Midi) | 12h20 | 10:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
FlixBus · FlixBus | 10:40 AM Brussels, Brussels South (Gare du Midi) | 12h10 | 10:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
1646 · 50107 | 12:30 PM Brussels, Brussels South (Gare du Midi) | 10h50 | 11:20 PM Lyon, Perrache Bus Station | 1 transfer | |
FlixBus · FlixBus | 1:15 PM Brussels, Brussels South (Gare du Midi) | 13h05 | 2:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
FlixBus · FlixBus | 3:40 PM Brussels, Brussels South (Gare du Midi) | 11h20 | 3:00 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
50336 · 5287 | 3:55 PM Brussels, Brussels South (Gare du Midi) | 10h30 | 2:25 AM Lyon, Perrache Bus Station | 1 transfer | |
1408 · 83133 | 4:55 PM Brussels, Brussels South (Gare du Midi) | 10h10 | 3:05 AM Lyon, Perrache Bus Station | 1 transfer | |
50338 · 5133 | 6:05 PM Brussels, Brussels South (Gare du Midi) | 10h15 | 4:20 AM Lyon, Perrache Bus Station | 1 transfer | |
FlixBus | 7:15 PM Brussels, Brussels South (Gare du Midi) | 10h35 | 5:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 0 transfersDirect | |
50828 | 11:15 PM Brussels, Brussels South (Gare du Midi) | 9h50 | 9:05 AM Lyon, Perrache Bus Station | 0 transfersDirect | |
1608 · 94765 | 2:11 AM Brussels, Brussels South (Gare du Midi) | 11h29 | 1:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
FlixBus · FlixBus | 3:15 AM Brussels, Brussels South (Gare du Midi) | 11h10 | 2:25 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
50320 · 5131 | 6:20 AM Brussels, Brussels South (Gare du Midi) | 11h30 | 5:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gherlan) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Brussels to Lyon by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 14
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Feb 18
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Feb 20
Feb 21
Feb 22
Feb 23
Feb 24
Feb 25
Feb 26
Feb 27
Feb 28
Mar 01
Mar 02
Mar 03
Mar 04
Mar 05
Mar 06
Journey information
Overview: Bus from Brussels to Lyon
Buses from Brussels to Lyon run on average 17 times per day, taking around 9h 30m. Cheap bus tickets for this journey start at €19 if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 569 km distance in 9h 50m.
Distance 569 km |
Average bus duration 9h 30m |
Cheapest ticket price €19 |
Buses per day 17 |
Direct buses 3 |
Fastest bus 9h 50m |
First bus 00:10 |
Last bus 23:55 |
Bus providers: BlaBlaCar Bus, FlixBus, BlaBlaCar from Brussels to LyonYou can travel by bus between Brussels to Lyon with BlaBlaCar Bus, FlixBus, BlaBlaCar for as low as €19. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
BlaBlaCar
FAQs: Bus from Brussels to Lyon
Find answers to the most common questions about traveling from Brussels to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Brussels to Lyon
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Midi (in the station)
- Belgian Bites (in the station)
- Fritland Express (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 27, 49, 50, 78 Metro: 2, 6 Train: IC, S, Thalys, Eurostar
- 06:00-23:59
- Free Wi-Fi
- Cafeteria Noord (in the station)
- Quick Brussels Noord (in the station)
- Le Pain Quotidien (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 14, 57, 58 Metro: 2, 6 Train: IC, S1, S2
- 06:00-23:00
- Free Wi-Fi
- Café de la Gare (in the station)
- Le Bistrot de Lyon (0.5 km)
- Brasserie Georges (0.6 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: C19, C20, 31, 46, 49, 55, 60, S1 Metro: A Tram: T1, T2
Most popular bus connections from Brussels
More options for your journey from Brussels to Lyon
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