The cheapest and fastest buses from Brussels to Lyon
Cheapest price
€35
Average price
€57
Fastest journey
10 h 20 m
Average duration
10 h 29 m
Buses per day
24
Distance
569 km
The best way to find a cheap bus ticket from Brussels to Lyon is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Brussels to Lyon will cost around €57 if you buy it on the day, but the cheapest tickets can be found for only €35.
Of the 24 buses that leave Brussels for Lyon on Sat, Aug 15, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Aug 15 the direct buses cover the 569 km distance in an average of 10 h 29 m but if you time it right, some buses will get you there in just 10 h 20 m .
On Sat, Aug 15 the slowest buses will take 10 h 35 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
1680 · 507553:30 PM10h50Brussels, Brussels South (Gare du Midi)2:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€351One-way1 transfer
50332 · 47812:20 PM11h20Brussels, Brussels South (Gare du Midi)1:40 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€371One-way1 transfer
1646 · 501071:30 PM10h50Brussels, Brussels South (Gare du Midi)12:20 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€371One-way1 transfer
1408 · 58075:55 PM10h35Brussels, Brussels South (Gare du Midi)4:30 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€401One-way1 transfer
50310 · 9476312:05 PM11h45Brussels, Brussels South (Gare du Midi)11:50 PMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€401One-way1 transfer
50338 · 47877:05 PM10h20Brussels, Brussels South (Gare du Midi)5:25 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€451One-way1 transfer
50338 · 508837:05 PM10h20Brussels, Brussels South (Gare du Midi)5:25 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€451One-way1 transfer
FlixBus8:15 PM10h35Brussels, Brussels South (Gare du Midi)6:50 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€861One-way0 transfers
50336 · 506174:55 PM10h35Brussels, Brussels South (Gare du Midi)3:30 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€431One-way1 transfer
1408 · 58075:55 PM10h35Brussels, Brussels South (Gare du Midi)4:30 AMLyon, Avenue Tony Garnier (Gare routière de Lyon Gerland)€401One-way1 transfer
Travel Information
Compare train, bus, and flight for Brussels to Lyon
Omio recommends booking the train as it is the most popular option from Brussels to Lyon among Omio's users. If you are prioritising price take the bus with prices starting from €21. For those with little time consider booking a flight which can get you there in 2h 24m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.5kg. The ticket price range depends on the travel mode: a bus costs an average of €21, and a flight costs an average of €118.
Distance: 569 km
Compare bus with
| Bus | Most popular Train | Flight |
|---|---|---|
€43 Average price Cheapest | €148 Average price | €306 Average price |
10h 2m Average total duration 9h 32m Onboard + 30m Additional time* | 3h 47m Average total duration 3h 17m Onboard + 30m Additional time* | 5h 24m Average total duration Fastest 2h 24m Onboard + 3h 0m Additional time* |
0.6 - 1.4kg CO2 emissions | 0.2 - 0.5kg CO2 emissions Lowest | 1.7 - 3.4kg CO2 emissions |
![]() Most popular bus company | ![]() Most popular train company | ![]() Most popular airline |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Brussels to Lyon bus times
The table below shows live departures for Brussels to Lyon buses for today, Friday, August 14. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 4:15 AM Brussels, Brussels South (Gare du Midi) | 12h10 | 4:25 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
50320 · 5131 | 7:20 AM Brussels, Brussels South (Gare du Midi) | 11h30 | 6:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
1430 · 50471 | 8:05 AM Brussels, Brussels South (Gare du Midi) | 11h05 | 7:10 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
3275 · 51991 | 8:35 AM Brussels, Brussels South (Gare du Midi) | 13h05 | 9:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 10:05 AM Brussels, Gare Du Midi | 13h45 | 11:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 11:20 AM Brussels, Brussels South (Gare du Midi) | 12h30 | 11:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 11:35 AM Brussels, Brussels South (Gare du Midi) | 13h30 | 1:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 2 transfers | |
50310 · 94763 | 12:05 PM Brussels, Brussels South (Gare du Midi) | 11h45 | 11:50 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
1646 · 50107 | 1:30 PM Brussels, Brussels South (Gare du Midi) | 10h50 | 12:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
50332 · 3357 | 2:20 PM Brussels, Brussels South (Gare du Midi) | 10h30 | 12:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 3:10 PM Brussels, Brussels South (Gare du Midi) | 10h50 | 2:00 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
1680 · 50755 | 3:30 PM Brussels, Brussels South (Gare du Midi) | 10h50 | 2:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 3:40 PM Brussels, Brussels South (Gare du Midi) | 10h40 | 2:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
50429 · 83133 | 3:50 PM Brussels, Brussels South (Gare du Midi) | 12h15 | 4:05 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 4:40 PM Brussels, Brussels South (Gare du Midi) | 12h10 | 4:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
50336 · 50617 | 4:55 PM Brussels, Brussels South (Gare du Midi) | 10h35 | 3:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus · FlixBus | 5:40 PM Brussels, Brussels South (Gare du Midi) | 10h55 | 4:35 AM Lyon | 1 transfer | |
1408 · 5807 | 5:55 PM Brussels, Brussels South (Gare du Midi) | 10h35 | 4:30 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
51112 · 5133 | 6:20 PM Brussels, Brussels South (Gare du Midi) | 11h00 | 5:20 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
50338 · 50883 | 7:05 PM Brussels, Brussels South (Gare du Midi) | 10h20 | 5:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
50338 · 4787 | 7:05 PM Brussels, Brussels South (Gare du Midi) | 10h20 | 5:25 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
FlixBus | 8:15 PM Brussels, Brussels South (Gare du Midi) | 10h35 | 6:50 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
51094 | 10:15 PM Brussels, Brussels South (Gare du Midi) | 11h00 | 9:15 AM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 0 transfersDirect | |
| Saturday, August 15 | |||||
FlixBus · FlixBus | 1:30 AM Brussels, Brussels South (Gare du Midi) | 11h05 | 12:35 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
1698 · 58073 | 2:15 AM Brussels, Brussels South (Gare du Midi) | 11h25 | 1:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
1608 · 94765 | 3:11 AM Brussels, Brussels South (Gare du Midi) | 11h29 | 2:40 PM Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Brussels to Lyon by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Aug 14
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Sep 01
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Sep 03
Why should you book Brussels to Lyon buses with Omio?
Why book with Omio vs BlaBlaCar Bus?
- Compare with other providers: On Omio, you can not only buy tickets for BlaBlaCar Bus, but also compare tickets for the likes of FlixBus to find the best option for your trip from Brussels to Lyon.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare BlaBlaCar Bus with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Brussels to Lyon.
Why book with Omio over Checkmybus, Wanderu or Busbud?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Brussels to Lyon.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Brussels to Lyon.
Journey information
Overview: Bus from Brussels to Lyon
Buses from Brussels to Lyon run on average 15 times per day, taking around 9h 32m. Cheap bus tickets for this journey start at €21 if you book in advance.
There are 3 buses per day. The earliest bus runs at 00:10, the last at 23:55. The fastest bus covers the 569 km distance in 9h 50m.
Distance 569 km |
Average bus duration 9h 32m |
Cheapest ticket price €21 |
Buses per day 15 |
Direct buses 3 |
Fastest bus 9h 50m |
First bus 12:10 AM |
Last bus 11:55 PM |
Cheapest Month Sep |
Cheapest Day Sat |
High Season Apr - Jun |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Sun |
Best time to book 84 days |
Bus providers: BlaBlaCar Bus, FlixBus, BlaBlaCar from Brussels to LyonYou can travel by bus between Brussels to Lyon with BlaBlaCar Bus, FlixBus, BlaBlaCar for as low as €21. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
BlaBlaCar Bus
BlaBlaCar
FAQs: Bus from Brussels to Lyon
Find answers to the most common questions about traveling from Brussels to Lyon by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Lyon, this guide helps you travel smarter and with confidence.

- BlaBlaCar Bus
- Assistance
- Priority boarding
- Accessible seating options.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- BlaBlaCar Bus
- You can cancel your ticket up to 30 minutes before departure for a refund in the form of a voucher.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- BlaBlaCar Bus
- One carry-on bag up to 7kg and one checked bag up to 20kg.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- BlaBlaCar Bus
- Additional luggage can be purchased for a fee.
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Brussels to Lyon
Most Brussels to Lyon buses use the Brussels, Brussels South (Gare du Midi) to Lyon, Gare Routière de Perrache station pair, with some services arriving at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). Use this guide to compare Brussels and Lyon bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Which Brussels station do buses to Lyon leave from?
Getting to Brussels, Brussels South (Gare du Midi) from Brussels city centre
Brussels, Brussels South (Gare du Midi) is 2 km from Brussels city centre. Public transport options include:
Brussels, Brussels South (Gare du Midi) bus station facilities and services
Brussels, Brussels South (Gare du Midi) has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Midi (in the station), Belgian Bites (in the station), Fritland Express (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and throughout the station.
Tickets and information
Ticket office support is available at Brussels, Brussels South (Gare du Midi).
Parking, taxis and toilets
Available at Brussels, Brussels South (Gare du Midi): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussels, Brussels South (Gare du Midi): Elevators, ramps.
Getting to Brussels, Gare Du Midi from Brussels city centre
Brussels, Gare Du Midi is 1 km from Brussels city centre. Public transport options include:
Brussels, Gare Du Midi bus station facilities and services
Brussels, Gare Du Midi has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Food and drink
Food options include: Various dining options are nearby.
Wi-Fi and ATMs
Wi-Fi is available at Brussels, Gare Du Midi. ATMs are available at Brussels, Gare Du Midi.
Tickets and information
Ticket office support is available at Brussels, Gare Du Midi.
Parking, taxis and toilets
Available at Brussels, Gare Du Midi: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussels, Gare Du Midi: Station is accessible for individuals with disabilities.
Getting to Brussels-Noord from Brussels city centre
Brussels-Noord is 1 km from Brussels city centre. Public transport options include:
Brussels-Noord bus station facilities and services
Brussels-Noord has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Cafeteria Noord (in the station), Quick Brussels Noord (in the station), Le Pain Quotidien (0.5 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance and in the waiting area.
Tickets and information
Ticket office support is available at Brussels-Noord.
Parking, taxis and toilets
Available at Brussels-Noord: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Brussels-Noord: Elevators, ramps.
Which Lyon station do buses from Brussels arrive at?
Getting to Lyon, Gare Routière de Perrache from Lyon city centre
Lyon, Gare Routière de Perrache is 1 km from Lyon city centre. Public transport options include:
Lyon, Gare Routière de Perrache bus station facilities and services
Lyon, Gare Routière de Perrache has practical services for this route, including Wifi, Parking, Dining, ATM, Taxis, Accessibility, WC, and Ticket Office.
Food and drink
Food options include: Café de la Gare (in the station), Le Bistrot de Lyon (0.5 km), Brasserie Georges (0.6 km).
Wi-Fi and ATMs
Free Wi-Fi. ATMs are located near the main entrance.
Tickets and information
Ticket office support is available at Lyon, Gare Routière de Perrache.
Parking, taxis and toilets
Available at Lyon, Gare Routière de Perrache: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, Gare Routière de Perrache: Elevators, ramps.
Getting to Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) from Lyon city centre
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) is 2 km from Lyon city centre. Public transport options include:
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) bus station facilities and services
Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland) has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland). ATMs are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Tickets and information
Ticket office support is available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland).
Parking, taxis and toilets
Available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, Avenue Tony Garnier (Gare routière de Lyon Gerland): Station is accessible for passengers with reduced mobility.
Getting to Lyon, St Exupéry Aéroport from Lyon city centre
Lyon, St Exupéry Aéroport is 2 km from Lyon city centre. Public transport options include:
Lyon, St Exupéry Aéroport bus station facilities and services
Lyon, St Exupéry Aéroport has practical services for this route, including Wifi, Parking, ATM, Taxis, Accessibility, WC, Shower, and Ticket Office.
Wi-Fi and ATMs
Wi-Fi is available at Lyon, St Exupéry Aéroport. ATMs are available at Lyon, St Exupéry Aéroport.
Tickets and information
Ticket office support is available at Lyon, St Exupéry Aéroport.
Parking, taxis and toilets
Available at Lyon, St Exupéry Aéroport: Parking, Taxis, WC.
Accessibility
Accessibility facilities are available at Lyon, St Exupéry Aéroport: Access ramps and services available.
Most popular bus connections from Brussels
More options for your journey from Brussels to Lyon
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