The cheapest and fastest buses from Palermo to Rome
Cheapest price
€61
Average price
€80
Fastest journey
12 h 15 m
Average duration
16 h 7 m
Buses per day
5
Distance
427 km
The best way to find a cheap bus ticket from Palermo to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Rome will cost around €80 if you buy it on the day, but the cheapest tickets can be found for only €61.
Of the 5 buses that leave Palermo for Rome on Sat, Apr 11, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Apr 11 the direct buses cover the 427 km distance in an average of 16 h 7 m but if you time it right, some buses will get you there in just 12 h 15 m .
On Sat, Apr 11 the slowest buses will take 20 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
S2026:00 PM12h15Palermo, Via Tommaso Fazello (Terminal Bus)6:15 AMRoma, Autostazione Tiburtina€611One-way0 transfers
FlixBus · FlixBus11:05 AM18h30Palermo, Via Tommaso Fazello (Terminal Bus)5:35 AMRoma, Autostazione Tiburtina€641One-way1 transfer
FlixBus9:10 PM14h20Palermo, Via Tommaso Fazello (Terminal Bus)11:30 AMRoma, Autostazione Tiburtina€641One-way0 transfers
FlixBus · FlixBus9:10 PM20h05Palermo, Via Tommaso Fazello (Terminal Bus)5:15 PMRoma, Autostazione (Metro Anagnina)€791One-way1 transfer
FlixBus · FlixBus3:25 PM15h25Palermo, Via Tommaso Fazello (Terminal Bus)6:50 AMRoma, Autostazione Tiburtina€1331One-way1 transfer
S2026:00 PM12h15Palermo, Via Tommaso Fazello (Terminal Bus)6:15 AMRoma, Autostazione Tiburtina€611One-way0 transfers
FlixBus9:10 PM14h20Palermo, Via Tommaso Fazello (Terminal Bus)11:30 AMRoma, Autostazione Tiburtina€641One-way0 transfers
FlixBus · FlixBus3:25 PM15h25Palermo, Via Tommaso Fazello (Terminal Bus)6:50 AMRoma, Autostazione Tiburtina€1331One-way1 transfer
FlixBus · FlixBus11:05 AM18h30Palermo, Via Tommaso Fazello (Terminal Bus)5:35 AMRoma, Autostazione Tiburtina€641One-way1 transfer
FlixBus · FlixBus9:10 PM20h05Palermo, Via Tommaso Fazello (Terminal Bus)5:15 PMRoma, Autostazione (Metro Anagnina)€791One-way1 transfer
Travel Information
Compare train, bus, flight, and ferry for Palermo to Rome
Omio recommends booking the flight as it is the most popular option from Palermo to Rome among Omio's users. If you are prioritising price take the ferry with prices starting from €50. For those with little time consider booking a flight which can get you there in 4h 33m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a ferry costs an average of €50, and a flight costs an average of €19.
Distance: 427 km
Compare bus with
| Bus | Most popular Flight | Train | Ferry |
|---|---|---|---|
€69 Average price | €115 Average price | €87 Average price | €56 Average price Cheapest |
11h 38m Average total duration 11h 8m Onboard + 30m Additional time* | 7h 33m Average total duration Fastest 4h 33m Onboard + 3h 0m Additional time* | 10h 45m Average total duration 10h 15m Onboard + 30m Additional time* | 14h 18m Average total duration 13h 18m Onboard + 1h 0m Additional time* |
0.4 - 1.1kg CO2 emissions | 1.3 - 2.6kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest | - CO2 emissions |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company | ![]() Most popular ferry company |
Direct Options | Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Palermo to Rome bus times
The table below shows live departures for Palermo to Rome buses for today, Friday, April 10. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 9:05 AM Palermo, Via Tommaso Fazello (Terminal Bus) | 18h30 | 3:35 AM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 1:25 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 15h25 | 4:50 AM Roma, Autostazione Tiburtina | 1 transfer | |
S202 | 4:00 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 12h15 | 4:15 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 7:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 14h20 | 9:30 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 7:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 20h05 | 3:15 PM Roma, Autostazione (Metro Anagnina) | 1 transfer |
Find all the dates and times for this journey
Compare prices and tickets Palermo to Rome by train, bus, flight, or ferry
Compare train, bus, flight, and ferry prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 10
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Why should you book Palermo to Rome buses with Omio?
Why book with Omio vs Autoservizi Salemi?
- Compare with other providers: On Omio, you can not only buy tickets for Autoservizi Salemi, but also compare tickets for the likes of Itabus, FlixBus or Infobus to find the best option for your trip from Palermo to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Autoservizi Salemi with all available travel options, which are train, bus, flight and ferry to ensure you get the best deal for traveling from Palermo to Rome.
Journey information
Overview: Bus from Palermo to Rome
Buses from Palermo to Rome run on average 3 times per day, taking around 11h 8m. Cheap bus tickets for this journey start at €29 but you can travel from only €19 by flight.
There are 1 buses per day. The earliest bus runs at 01:05, the last at 23:45. The fastest bus covers the 427 km distance in 13h 25m.
Distance 427 km |
Average bus duration 11h 8m |
Cheapest ticket price €29 |
Buses per day 3 |
Direct buses 1 |
Fastest bus 13h 25m |
First bus 1:05 AM |
Last bus 11:45 PM |
Bus providers: Autoservizi Salemi, Itabus, FlixBus, BlaBlaCar, Infobus from Palermo to RomeYou can travel by bus between Palermo to Rome with Autoservizi Salemi, Itabus, FlixBus, BlaBlaCar, Infobus for as low as €19. When you search for schedules and tickets, Omio will show you the best journey
Itabus
FlixBus
Infobus
Autoservizi Salemi
BlaBlaCar
FAQs: Bus from Palermo to Rome
Find answers to the most common questions about traveling from Palermo to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Itabus
- Assistance
- Dedicated seating areas
- Accessible restrooms.
- Autoservizi Salemi
- The cancellation policy can vary by ticket class, individual trips, or promotions, so it's best to check the terms during booking.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Itabus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Changes allowed for a fee.
- Autoservizi Salemi
- Two pieces of luggage: one large suitcase for the hold and one smaller backpack for on-board.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Itabus
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Itabus
- 5€ per additional bag.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Itabus
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
popular bus stations
Popular bus stations from Palermo to Rome
- 06:00-23:00
- Free Wi-Fi
- Ristorante Italiano (in the station)
- Fast Food Express (in the station)
- Caffè del Terminal (in the station).
- Available outside the arrivals terminal.
- Elevators, ramps
- Available in the station.
- Bus: 520, 720 Train: Leonardo Express
Most popular bus connections from Palermo
More options for your journey from Palermo to Rome
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