The cheapest and fastest buses from Pisa to Brindisi
Cheapest price
€91
Average price
€113
Fastest journey
13 h
Average duration
13 h 35 m
Buses per day
8
Distance
710 km
The best way to find a cheap bus ticket from Pisa to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Brindisi will cost around €113 if you buy it on the day, but the cheapest tickets can be found for only €91.
Of the 8 buses that leave Pisa for Brindisi on Sun, Dec 21, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sun, Dec 21 the direct buses cover the 710 km distance in an average of 13 h 35 m but if you time it right, some buses will get you there in just 13 h .
On Sun, Dec 21 the slowest buses will take 13 h 50 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
104 · 108
207
FlixBus · FlixBus
FlixBus · FlixBus
FlixBus · FlixBus
104 · 108
FlixBus · FlixBus
FlixBus · FlixBus
207
FlixBus · FlixBusTravel Information
Compare train, bus, and flight for Pisa to Brindisi
Omio recommends booking the flight as it is the most popular option from Pisa to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from €47. For those with little time consider booking a flight which can get you there in 1h 27m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €47, and a flight costs an average of €28.
Distance: 710 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€69 Average price Cheapest | €154 Average price | €78 Average price |
14h 28m Average total duration 13h 58m Onboard + 30m Additional time* | 4h 27m Average total duration Fastest 1h 27m Onboard + 3h 0m Additional time* | 9h 30m Average total duration 9h 0m Onboard + 30m Additional time* |
0.7 - 1.8kg CO2 emissions | - CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Pisa to Brindisi bus times
The table below shows live departures for Pisa to Brindisi buses for today, Saturday, December 20. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 4:45 AM Pisa, Aeroporto Parcheggio Aurelia | 13h45 | 6:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 5:00 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h30 | 6:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 12:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 16h45 | 5:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 4:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h50 | 6:15 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
104 · 108 | 6:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h00 | 7:25 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 9:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 15h25 | 12:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 11:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 16h20 | 3:45 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Brindisi by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Dec 21
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Journey information
Overview: Bus from Pisa to Brindisi
Buses from Pisa to Brindisi run on average 6 times per day, taking around 13h 58m. Cheap bus tickets for this journey start at €47 but you can travel from only €28 by flight.
There are 1 buses per day. The earliest bus runs at 00:25, the last at 23:30. The fastest bus covers the 710 km distance in 13h 0m.
Distance 710 km |
Average bus duration 13h 58m |
Cheapest ticket price €47 |
Buses per day 6 |
Direct buses 1 |
Fastest bus 13h 0m |
First bus 00:25 |
Last bus 23:30 |
Bus providers: Marino Autolinee, FlixBus from Pisa to BrindisiYou can travel by bus between Pisa to Brindisi with Marino Autolinee, FlixBus for as low as €28. When you search for schedules and tickets, Omio will show you the best journey
Marino Autolinee
FlixBus
FAQs: Bus from Pisa to Brindisi
Find answers to the most common questions about traveling from Pisa to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

When departing from Pisa, you have various coach station options to start your trip from including Pisa, Aeroporto internazionale “Galileo Galilei” (P6), Pisa, Staz. FS and Pisa, Via delle Fiamme Gialle (Park Pietrasantina). When arriving in Brindisi, you can end your journey in coach stations like Brindisi, Aeroporto, Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) and Brindisi, Ospedale Antonio Perrino.
Passengers board the coach most frequently from Pisa, Aeroporto internazionale “Galileo Galilei” (P6), which is located around 1.2 miles (1.9 km) away from the city centre, and they get off the coach at Brindisi, Aeroporto, located 3.1 miles (5 km) away from the city centre.
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Popular bus stations from Pisa to Brindisi
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