The cheapest and fastest buses from Pisa to Brindisi
Cheapest price
€67
Average price
€78
Fastest journey
13 h
Average duration
17 h 20 m
Buses per day
4
Distance
710 km
The best way to find a cheap bus ticket from Pisa to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Brindisi will cost around €78 if you buy it on the day, but the cheapest tickets can be found for only €67.
Of the 4 buses that leave Pisa for Brindisi on Wed, Nov 05, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Nov 05 the direct buses cover the 710 km distance in an average of 17 h 20 m but if you time it right, some buses will get you there in just 13 h .
On Wed, Nov 05 the slowest buses will take 1 d 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
207
104 · 108
FlixBus · FlixBus · FlixBus
FlixBus · FlixBus
104 · 108
207
FlixBus · FlixBus
FlixBus · FlixBus · FlixBusTravel Information
Compare train, bus, and flight for Pisa to Brindisi
Omio recommends booking the flight as it is the most popular option from Pisa to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from €47. For those with little time consider booking a flight which can get you there in 1h 27m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €47, and a flight costs an average of €28.
Distance: 710 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€69 Average price Cheapest | €154 Average price | €78 Average price |
14h 28m Average total duration 13h 58m Onboard + 30m Additional time* | 4h 27m Average total duration Fastest 1h 27m Onboard + 3h 0m Additional time* | 9h 30m Average total duration 9h 0m Onboard + 30m Additional time* |
0.7 - 1.8kg CO2 emissions | - CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Pisa to Brindisi bus times
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus · FlixBus | 6:10 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 24h05 | 6:15 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
207 | 7:20 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h50 | 9:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
FlixBus · FlixBus | 3:55 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 18h25 | 10:20 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
104 · 108 | 6:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h00 | 7:25 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Brindisi by train, bus, or flight
Nov 05
Nov 06
Nov 07
Nov 08
Nov 09
Nov 10
Nov 11
Nov 12
Nov 13
Nov 14
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Nov 17
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Nov 25
Journey information
Overview: Bus from Pisa to Brindisi
Distance 710 km |
Average bus duration 13h 58m |
Cheapest ticket price €47 |
Buses per day 6 |
Direct buses 1 |
Fastest bus 13h 0m |
First bus 00:25 |
Last bus 23:30 |
Bus providers: Marino Autolinee, FlixBus from Pisa to BrindisiYou can travel by bus between Pisa to Brindisi with Marino Autolinee, FlixBus for as low as €28. When you search for schedules and tickets, Omio will show you the best journey
Marino Autolinee
FlixBus
FAQs: Bus from Pisa to Brindisi

When departing from Pisa, you have various coach station options to start your trip from including Pisa, Aeroporto internazionale “Galileo Galilei” (P6), Pisa, Staz. FS and Pisa, Via delle Fiamme Gialle (Park Pietrasantina). When arriving in Brindisi, you can end your journey in coach stations like Brindisi, Aeroporto, Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) and Brindisi, Ospedale Antonio Perrino.
Passengers board the coach most frequently from Pisa, Aeroporto internazionale “Galileo Galilei” (P6), which is located around 1.2 miles (1.9 km) away from the city centre, and they get off the coach at Brindisi, Aeroporto, located 3.1 miles (5 km) away from the city centre.
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