The cheapest and fastest buses from Pisa to Brindisi
Cheapest price
€61
Average price
€96
Fastest journey
13 h 5 m
Average duration
14 h 33 m
Buses per day
8
Distance
710 km
The best way to find a cheap bus ticket from Pisa to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Brindisi will cost around €96 if you buy it on the day, but the cheapest tickets can be found for only €61.
Of the 8 buses that leave Pisa for Brindisi on Fri, Jun 19, 1 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jun 19 the direct buses cover the 710 km distance in an average of 14 h 33 m but if you time it right, some buses will get you there in just 13 h 5 m .
On Fri, Jun 19 the slowest buses will take 16 h 5 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
131 · 1087:20 PM13h05Pisa, Via delle Fiamme Gialle (Park Pietrasantina)8:25 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€611One-way1 transfer
2078:20 AM13h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:10 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€681One-way0 transfers
FlixBus · FlixBus4:45 AM17h40Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:25 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€831One-way1 transfer
FlixBus · FlixBus12:25 AM16h05Pisa, Via delle Fiamme Gialle (Park Pietrasantina)4:30 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€921One-way1 transfer
FlixBus · FlixBus5:25 PM13h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)7:15 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€941One-way1 transfer
131 · 1087:20 PM13h05Pisa, Via delle Fiamme Gialle (Park Pietrasantina)8:25 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€611One-way1 transfer
FlixBus · FlixBus5:25 PM13h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)7:15 AMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€941One-way1 transfer
2078:20 AM13h50Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:10 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€681One-way0 transfers
FlixBus · FlixBus10:00 PM15h55Pisa, Via delle Fiamme Gialle (Park Pietrasantina)1:55 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€1271One-way1 transfer
FlixBus · FlixBus12:25 AM16h05Pisa, Via delle Fiamme Gialle (Park Pietrasantina)4:30 PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)€921One-way1 transfer
Travel Information
Compare train, bus, and flight for Pisa to Brindisi
Omio recommends booking the flight as it is the most popular option from Pisa to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from €28. For those with little time consider booking a flight which can get you there in 1h 28m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.2 - 0.6kg. The ticket price range depends on the travel mode: a bus costs an average of €28, and a flight costs an average of €17.
Distance: 710 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€53 Average price Cheapest | €101 Average price | €73 Average price |
14h 7m Average total duration 13h 37m Onboard + 30m Additional time* | 4h 28m Average total duration Fastest 1h 28m Onboard + 3h 0m Additional time* | 10h 3m Average total duration 9h 33m Onboard + 30m Additional time* |
0.7 - 1.8kg CO2 emissions | - CO2 emissions | 0.2 - 0.6kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Pisa to Brindisi bus times
The table below shows live departures for Pisa to Brindisi buses for today, Thursday, June 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 10:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 15h55 | 1:55 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
| Friday, June 19 | |||||
FlixBus · FlixBus | 12:25 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 16h05 | 4:30 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 4:45 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 17h40 | 10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus · FlixBus | 6:05 AM Pisa, Aeroporto Parcheggio Aurelia | 16h20 | 10:25 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 2 transfers | |
207 | 8:20 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h50 | 10:10 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 0 transfersDirect | |
FlixBus · FlixBus | 1:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 16h45 | 6:10 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
FlixBus · FlixBus | 5:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 13h50 | 7:15 AM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Pisa to Brindisi by train, bus, or flight
Compare train, bus, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jun 19
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Jul 09
Why should you book Pisa to Brindisi buses with Omio?
Why book with Omio vs Marino Autolinee?
- Compare with other providers: On Omio, you can not only buy tickets for Marino Autolinee, but also compare tickets for the likes of FlixBus to find the best option for your trip from Pisa to Brindisi.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare Marino Autolinee with all available travel options, which are train, bus and flight to ensure you get the best deal for traveling from Pisa to Brindisi.
Why book with Omio over Checkmybus, Wanderu or Trainline?
- Compare with other providers: On Omio, you can also compare tickets for the likes of FlixBus to find the best option for your trip from Pisa to Brindisi.
- Multiple modes of transport: Omio allows you to compare travel options including train, bus and flight to find the ideal travel option from Pisa to Brindisi.
Journey information
Overview: Bus from Pisa to Brindisi
Buses from Pisa to Brindisi run on average 6 times per day, taking around 13h 37m. Cheap bus tickets for this journey start at €28 but you can travel from only €17 by flight.
There are 1 buses per day. The earliest bus runs at 00:25, the last at 23:30. The fastest bus covers the 710 km distance in 13h 5m.
Distance 710 km |
Average bus duration 13h 37m |
Cheapest ticket price €28 |
Buses per day 6 |
Direct buses 1 |
Fastest bus 13h 5m |
First bus 12:25 AM |
Last bus 11:30 PM |
Cheapest Month Feb |
Cheapest Day Mon |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Tue |
Least Busy Day Sun |
Best time to book 1 day |
Bus providers: Marino Autolinee, FlixBus from Pisa to BrindisiYou can travel by bus between Pisa to Brindisi with Marino Autolinee, FlixBus for as low as €17. When you search for schedules and tickets, Omio will show you the best journey
Marino Autolinee
FlixBus
FAQs: Bus from Pisa to Brindisi
Find answers to the most common questions about traveling from Pisa to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Pisa to Brindisi
Most popular bus connections from Pisa
More options for your journey from Pisa to Brindisi
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