The cheapest and fastest buses from Palermo to Brindisi
Cheapest price
€64
Average price
€85
Fastest journey
23 h 10 m
Average duration
23 h 15 m
Buses per day
2
Distance
482 km
The best way to find a cheap bus ticket from Palermo to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Brindisi will cost around €85 if you buy it on the day, but the cheapest tickets can be found for only €64.
Of the 2 buses that leave Palermo for Brindisi on Wed, Feb 04, 2 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Wed, Feb 04 the direct buses cover the 482 km distance in an average of 23 h 15 m but if you time it right, some buses will get you there in just 23 h 10 m .
On Wed, Feb 04 the slowest buses will take 23 h 20 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.




Travel Information
Compare bus, train, and flight for Palermo to Brindisi
Omio recommends booking the flight as it is the most popular option from Palermo to Brindisi among Omio's users. If you are prioritising price take the train with prices starting from €31. For those with little time consider booking a flight which can get you there in 1h 42m. The ticket price range depends on the travel mode: a train costs an average of €31, and a flight costs an average of €29.
Distance: 482 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€88 Average price | €140 Average price | €73 Average price Cheapest |
12h 13m Average total duration 11h 43m Onboard + 30m Additional time* | 4h 42m Average total duration Fastest 1h 42m Onboard + 3h 0m Additional time* | 14h 14m Average total duration 13h 44m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Live departures
Palermo to Brindisi bus times
The table below shows live departures for Palermo to Brindisi buses for today, Tuesday, February 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 4:15 PM Palermo | 11h45 | 4:00 AM Brindisi | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Palermo to Brindisi by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Feb 04
Feb 05
Feb 06
Feb 07
Feb 08
Feb 09
Feb 10
Journey information
Overview: Bus from Palermo to Brindisi
Buses from Palermo to Brindisi run on average 1 times per day, taking around 11h 43m. Cheap bus tickets for this journey start at €39 but you can travel from only €29 by flight.
There are 1 buses per day. The earliest bus runs at 04:21, the last at 23:30. The fastest bus covers the 482 km distance in 11h 45m.
Distance 482 km |
Average bus duration 11h 43m |
Cheapest ticket price €39 |
Buses per day 1 |
Direct buses 1 |
Fastest bus 11h 45m |
First bus 04:21 |
Last bus 23:30 |
Bus providers: FlixBus, Sais Autolinee, Infobus, BlaBlaCar, Autoservizi Salemi Srl from Palermo to BrindisiYou can travel by bus between Palermo to Brindisi with FlixBus, Sais Autolinee, Infobus, BlaBlaCar, Autoservizi Salemi Srl for as low as €29. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Sais Autolinee
Infobus
BlaBlaCar
Autoservizi Salemi Srl
FAQs: Bus from Palermo to Brindisi
Find answers to the most common questions about traveling from Palermo to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

- Sais Autolinee
- Assistance
- Priority boarding
- Accessible seating.
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Sais Autolinee
- You can cancel your ticket up to 24 hours before departure for a partial refund. No refunds for cancellations within 24 hours.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Sais Autolinee
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Sais Autolinee
- Additional luggage can be purchased for a fee.
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Sais Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Palermo to Brindisi
Most popular bus connections from Palermo
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