The cheapest and fastest buses from Palermo to Brindisi
Cheapest price
€63
Average price
€74
Fastest journey
20 h 39 m
Average duration
22 h 30 m
Buses per day
3
Distance
482 km
The best way to find a cheap bus ticket from Palermo to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Brindisi will cost around €74 if you buy it on the day, but the cheapest tickets can be found for only €63.
Of the 3 buses that leave Palermo for Brindisi on Fri, Jun 19, 3 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Fri, Jun 19 the direct buses cover the 482 km distance in an average of 22 h 30 m but if you time it right, some buses will get you there in just 20 h 39 m .
On Fri, Jun 19 the slowest buses will take 23 h 30 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
7:10 PM20h39Palermo3:49 PMBrindisi€631One-way0 transfers
4:10 PM23h30Palermo3:40 PMBrindisi€721One-way0 transfers
4:20 PM23h20Palermo3:40 PMBrindisi€851One-way0 transfers
7:10 PM20h39Palermo3:49 PMBrindisi€631One-way0 transfers
4:20 PM23h20Palermo3:40 PMBrindisi€851One-way0 transfers
4:10 PM23h30Palermo3:40 PMBrindisi€721One-way0 transfers
Travel Information
Compare bus, train, and flight for Palermo to Brindisi
Omio recommends booking the flight as it is the most popular option from Palermo to Brindisi among Omio's users. If you are prioritising price take the bus with prices starting from €31. For those with little time consider booking a flight which can get you there in 1h 39m. The ticket price range depends on the travel mode: a bus costs an average of €31, and a flight costs an average of €109.
Distance: 482 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€61 Average price Cheapest | €150 Average price | €65 Average price |
12h 54m Average total duration 12h 24m Onboard + 30m Additional time* | 4h 39m Average total duration Fastest 1h 39m Onboard + 3h 0m Additional time* | 14h 22m Average total duration 13h 52m Onboard + 30m Additional time* |
![]() Most popular bus company | ![]() Most popular airline | ![]() Most popular train company |
Direct Options | Direct Options | Direct Options |
Live departures
Palermo to Brindisi bus times
The table below shows live departures for Palermo to Brindisi buses for today, Thursday, June 18. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
![]() | 7:10 PM Palermo | 20h39 | 3:49 PM Brindisi | 0 transfersDirect | |
| Friday, June 19 | |||||
![]() | 4:10 PM Palermo | 23h30 | 3:40 PM Brindisi | 0 transfersDirect | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Palermo to Brindisi by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Jun 18
Jun 19
Jun 20
Jun 21
Jun 22
Jun 23
Jun 24
Jun 25
Jun 26
Jun 27
Jun 28
Jun 29
Jun 30
Jul 01
Why should you book Palermo to Brindisi buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Sais Autolinee or Infobus to find the best option for your trip from Palermo to Brindisi.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Palermo to Brindisi.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Sais Autolinee or Infobus to find the best option for your trip from Palermo to Brindisi.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Palermo to Brindisi.
Journey information
Overview: Bus from Palermo to Brindisi
Buses from Palermo to Brindisi run on average 1 times per day, taking around 12h 24m. Cheap bus tickets for this journey start at €31 but you can travel from only €27 by train.
The earliest bus runs at 04:21, the last at 23:50. The fastest bus covers the 482 km distance in 20h 24m.
Distance 482 km |
Average bus duration 12h 24m |
Cheapest ticket price €31 |
Buses per day 1 |
Fastest bus 20h 24m |
First bus 4:21 AM |
Last bus 11:50 PM |
Cheapest Month Sep |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Mon |
Least Busy Day Wed |
Best time to book 21 days |
Bus providers: FlixBus, Sais Autolinee, Infobus from Palermo to BrindisiYou can travel by bus between Palermo to Brindisi with FlixBus, Sais Autolinee, Infobus for as low as €27. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Sais Autolinee
Infobus
FAQs: Bus from Palermo to Brindisi
Find answers to the most common questions about traveling from Palermo to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

- Sais Autolinee
- Assistance
- Priority boarding
- Accessible seating.
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Sais Autolinee
- You can cancel your ticket up to 24 hours before departure for a partial refund. No refunds for cancellations within 24 hours.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Sais Autolinee
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Sais Autolinee
- Additional luggage can be purchased for a fee.
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Sais Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Palermo to Brindisi
Most popular bus connections from Palermo
More options for your journey from Palermo to Brindisi
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