The cheapest and fastest buses from Palermo to Brindisi
- Cheapest price on Nov 02
- €53
- Average ticket price on Nov 02
- €53
- Fastest journey on Nov 02
- 20 h 24 m
- Average journey duration on Nov 02
- 20 h 24 m
- Buses on Nov 02
- 1
- Distance
- 482 km
The best way to find a cheap bus ticket from Palermo to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Brindisi will cost around €53 if you buy it on the day, but the cheapest tickets can be found for only €53.
It's difficult to get from Palermo to Brindisi without transferring at least once.
FlixBus · FlixBus9:10 PM 20h24 Palermo, Via Tommaso Fazello (Terminal Bus) 5:34 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) €53 1 One-way 1 transfer
FlixBus · FlixBus9:10 PM 20h24 Palermo, Via Tommaso Fazello (Terminal Bus) 5:34 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) €53 1 One-way 1 transfer
Journey information
Overview: Bus from Palermo to Brindisi
Buses from Palermo to Brindisi run on average 1 times per day, taking around 14h 51m. Cheap bus tickets for this journey start at €32 but you can travel from only €18 by flight.
There are 1 buses per day. The earliest bus runs at 04:21, the last at 23:50. The fastest bus covers the 482 km distance in 11h 45m.
Distance 482 km |
Average bus duration 14h 51m |
Cheapest ticket price €32 |
Buses per day 1 |
Direct buses 1 |
Fastest bus 11h 45m |
First bus 4:21 AM |
Last bus 11:50 PM |
Cheapest Month May |
Cheapest Day Tue |
High Season Jul - Sep |
Low Season Jan - Mar |
Busiest Day Wed |
Least Busy Day Sat |
Best time to book 14 days |
Frequently asked questions about your Palermo to Brindisi trip
Use these quick route answers to check fares, travel time, departure options, and direct services before booking from Palermo to Brindisi.
Live departures
Palermo to Brindisi bus times
The table below shows live departures for Palermo to Brindisi buses for today, Sunday, November 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 9:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 20h24 | 5:34 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Why should you book Palermo to Brindisi buses with Omio?
Why book with Omio vs FlixBus?
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Palermo to Brindisi.
Why book with Omio over Wanderu or Trainline?
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Palermo to Brindisi.
Bus providers: FlixBus from Palermo to BrindisiYou can travel by bus between Palermo to Brindisi with FlixBus for as low as €18. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Companies, tickets, and onboard amenities between Palermo and Brindisi
Review the details behind your booking, from operators and ticket rules to luggage, onboard amenities, accessibility, and route-specific travel policies.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- Additional luggage can be purchased for a fee.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
FAQs: Bus from Palermo to Brindisi
Find answers to the most common questions about traveling from Palermo to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.

popular bus stations
Popular bus stations from Palermo to Brindisi
Most Palermo to Brindisi buses use the to Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) station pair. Use this guide to compare Palermo and Brindisi bus stations on this route, check city-centre transport, alongside checking practicalities like bus station facilities and services.
Most popular bus connections from Palermo
More options for your journey from Palermo to Brindisi
Here are some other resources that might have the information you need
