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The cheapest and fastest buses from Palermo to Brindisi
Showing times and prices for Mar 21
Cheapest price
€78
Average price
€78
Fastest journey
23 h 30 m
Average duration
23 h 30 m
Buses per day
1
Distance
482 km
Cheap tickets
The best way to find a cheap bus ticket from Palermo to Brindisi is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Palermo to Brindisi will cost around €78 if you buy it on the day, but the cheapest tickets can be found for only €78.
Fast buses
It's difficult to get from Palermo to Brindisi without transferring at least once.
FlixBus · FlixBus05:10PM23h30
Palermo, Via Tommaso Fazello (Terminal Bus)04:40PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
€781One-way
1 transfer
FlixBus · FlixBus05:10PM23h30
Palermo, Via Tommaso Fazello (Terminal Bus)04:40PMBrindisi, Via Giuseppe Maria Galanti (Istituto Professionale)
€781One-way
1 transfer
Travel Information
Compare bus, train, and flight for Palermo to Brindisi
Omio recommends booking the flight as it is the most popular option from Palermo to Brindisi among Omio's users. If you are prioritising price take the train with prices starting from €26. For those with little time consider booking a flight which can get you there in 1h 39m. The ticket price range depends on the travel mode: a train costs an average of €26, and a flight costs an average of €109.
Distance: 482 km
Compare bus with
| Bus | Most popular Flight | Train |
|---|---|---|
€75 Average price | €186 Average price | €61 Average price Cheapest |
12h 57m Average total duration 12h 27m Onboard + 30m Additional time* | 4h 39m Average total duration Fastest 1h 39m Onboard + 3h 0m Additional time* | 14h 22m Average total duration 13h 52m Onboard + 30m Additional time* |
Most popular bus company |  Most popular airline |  Most popular train company |
Direct Options | Direct Options | Direct Options |
Live departures
Palermo to Brindisi bus times
The table below shows live departures for Palermo to Brindisi buses for today, Friday, March 20. You can also manually refresh the results below to see updated bus journeys.
Last updated at 8:16 AM
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
| FlixBus · FlixBus | 4:10 PM Palermo, Via Tommaso Fazello (Terminal Bus) | 23h30 | 3:40 PM Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale) | 1 transfer | |
This is the last bus of the day. | |||||
Find all the dates and times for this journey
Compare prices and tickets Palermo to Brindisi by bus, train, or flight
Compare bus, train, and flight prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Palermo to Brindisi buses with Omio?
FlixBus as well as Sais Autolinee, Infobus, Autoservizi Salemi Srl and more offer buses services from Palermo to Brindisi.
Omio is an official ticket reseller for all your travel options from Palermo to Brindisi.
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Sais Autolinee, Infobus or Autoservizi Salemi Srl to find the best option for your trip from Palermo to Brindisi.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus, train and flight to ensure you get the best deal for traveling from Palermo to Brindisi.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Sais Autolinee, Infobus or Autoservizi Salemi Srl to find the best option for your trip from Palermo to Brindisi.
- Multiple modes of transport: Omio allows you to compare travel options including bus, train and flight to find the ideal travel option from Palermo to Brindisi.
Journey information
Overview: Bus from Palermo to Brindisi
ItalyItaly
Buses from Palermo to Brindisi run on average 1 times per day, taking around 12h 27m. Cheap bus tickets for this journey start at €35 but you can travel from only €26 by train.
There are 1 buses per day. The earliest bus runs at 04:21, the last at 23:50. The fastest bus covers the 482 km distance in 23h 20m.
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €26
Distance 482 km |
Average bus duration 12h 27m |
Cheapest ticket price €35 |
Buses per day 1 |
Direct buses 1 |
Fastest bus 23h 20m |
First bus 04:21 |
Last bus 23:50 |
Fares are the lowest economy prices found on Omio. Early booking often means lower prices. Prices change daily and are subject to availability. Discount cards, coach trips, and booking fees are not included.
Price information
Cheapest alternative travel mode
Train from €26
Bus providers: FlixBus, Sais Autolinee, Infobus, Autoservizi Salemi Srl from Palermo to BrindisiYou can travel by bus between Palermo to Brindisi with FlixBus, Sais Autolinee, Infobus, Autoservizi Salemi Srl for as low as €26. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
About
FlixBus is one of Europe’s leading low-cost bus companies, founded in Germany and now offering long-distance services across Europe and the United States. In addition to its extensive daytime network, FlixBus also operates overnight buses on select European routes. Standard amenities include free Wi-Fi, power outlets to charge devices, extra legroom, luggage space, and onboard toilets, with snacks and drinks available for purchase. FlixBus offers a single Standard ticket type for all routes, which includes one carry-on bag and one checked bag per passenger. Additional fees apply for extra luggage and for reserving specific seats, such as Extra Seats, Table Seats, or Panorama Seats. This combination of affordability, comfort, and wide coverage makes FlixBus a popular choice for budget-conscious travelers.
Luggage & cancellation policy
Average Duration
23h 20m
Cheapest Price
€35
Luggage included
One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Wheelchair-accessible buses.
Bikes
Bikes are allowed for a fee; must be booked.
Pets
Small pets in carriers allowed; guide dogs travel for free.
Sais Autolinee
About
Sais Autolinee S.p.A. is an Italian bus company founded in Enna in 1926, providing urban, suburban, and intercity bus services primarily within Sicily and connecting to other destinations in Italy. With over 90 years of experience, Sais Autolinee is a prominent mobility provider in Sicily, offering more than 70 daily departures from major cities like Catania, Palermo, and Messina. The company focuses on comfort, safety, and technological innovation, aiming to provide enjoyable travel experiences with a modern and eco-friendly fleet. Popular routes include connections between Catania, Palermo, and Messina, as well as services to Catania Airport.
Luggage & cancellation policy
Average Duration
10h 45m
Cheapest Price
€42
Sais Autolinee frequency
1 a day
Luggage included
One carry-on bag up to 10kg and one checked bag up to 20kg.
Additional luggage
Additional luggage can be purchased for a fee.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. No refunds for cancellations within 24 hours.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority boarding; Accessible seating.
Bikes
Bikes are allowed; prior reservation is recommended.
Pets
Small pets allowed in carriers; larger pets must be leashed and muzzled.
Infobus
About
Infobus is an international IT company that operates as an online service for finding and purchasing bus, train, and plane tickets, rather than being a bus company itself. Established in 2002, Infobus acts as an intermediary between passengers and various transport carriers, particularly helping smaller bus companies offer online booking services. They utilize their own \BusSystem\" to manage routes and ticket sales globally. Infobus covers over 30 countries and 300 cities, offering a wide range of routes and daily departures. While amenities can vary by carrier, Infobus aims to provide affordable and convenient travel with features like online booking, 24/7 support, and prompt notifications."
Luggage & cancellation policy
Luggage included
One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
Additional luggage
10€ per additional bag.
Cancellation Policy
You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
Amenities on board the bus
Wifi
Food sold onboard
Seat reservation
Toilets
USB plugs
Accessibility
Assistance; Priority seating; Transport for wheelchairs and mobility aids.
Bikes
Bikes are allowed; may require prior reservation and an additional fee.
Pets
Small pets allowed in carriers; larger pets may require a separate ticket.
Autoservizi Salemi Srl
Luggage & cancellation policy
Average Duration
10h 45m
Cheapest Price
€40
Autoservizi Salemi Srl frequency
1 a day
FAQs: Bus from Palermo to Brindisi
Find answers to the most common questions about traveling from Palermo to Brindisi by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Brindisi, this guide helps you travel smarter and with confidence.
Cheap coach tickets from Palermo to Brindisi can start from as little as €35 when you book in advance. The average coach ticket price for Palermo to Brindisi is €75; however, prices vary depending on the time of day and class and they tend to be more expensive on the day.
The average journey time by coach from Palermo to Brindisi is 23h 20m to travel the 482 km long trip. Journey times can vary on weekends and holidays, so use our Journey Planner to search for a specific date.
The earliest coach from Palermo to Brindisi leaves at 4:21 AM. Plan your trip with the Journey Planner from Omio.
The latest coach from Palermo to Brindisi leaves at 11:50 PM.
Yes, there are 1 direct coaches a day from Palermo to Brindisi with . Schedules can vary on holidays or weekends with fewer direct coaches.
When taking a coach from Palermo to Brindisi, you can count on FlixBus, Sais Autolinee, Infobus, Autoservizi Salemi Srl for the best way to get you to Brindisi. You can also check all possible coach companies who offer a service between Palermo and Brindisi and compare the amenities they offer before buying a coach ticket.
Passengers board the coach most frequently from Palermo, Via Tommaso Fazello (Terminal Bus), which is located around 1 away from the city centre, and they get off the coach at Brindisi, Via Giuseppe Maria Galanti (Istituto Professionale), located 0 away from the city centre.
A trip to Brindisi from Palermo is worth doing but not as a day trip with a journey time of 23h 20m each way. Check with Omio app the best way to travel.
The cheapest month for a coach from Palermo to Brindisi is September.
It's helpful to compare your options as there are 3 ways to travel between Palermo and Brindisi including taking a bus, train, and flight.
Yes, the following accessibility options are available when taking the coach from Palermo to Brindisi:
- Sais Autolinee
- Assistance
- Priority boarding
- Accessible seating.
- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
Yes, there are bathrooms on board the coach from Palermo to Brindisi for coach company FlixBus, Sais Autolinee, Infobus.
Whether you can cancel your coach ticket from Palermo to Brindisi depends on the coach companies:
- Sais Autolinee
- You can cancel your ticket up to 24 hours before departure for a partial refund. No refunds for cancellations within 24 hours.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
Yes, bikes are allowed on board the coach with coach company FlixBus, Sais Autolinee, Infobus.
Tickets are often cheaper when booked early. Traveling during off-peak hours or on weekdays can help you save money. Sort results by price to quickly identify the most affordable options. Check for promotions or discounts available on our website and app.
No, there is no food available to purchase on board the coach from Palermo to Brindisi.
Yes, the following luggage options are included when booking a coach ticket from Palermo to Brindisi:
- Sais Autolinee
- One carry-on bag up to 10kg and one checked bag up to 20kg.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
Yes, the following additional luggage options are available when booking a coach ticket from Palermo to Brindisi:
- Sais Autolinee
- Additional luggage can be purchased for a fee.
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
Yes, you can bring your pet on the coach from Palermo to Brindisi. The following conditions apply:
- Sais Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
You can reserve your seat on the coach from Palermo to Brindisi with the following coach company: FlixBus, Sais Autolinee, Infobus
Yes, there are USB plugs on board the coach from Palermo to Brindisi with the following coach company: FlixBus, Sais Autolinee, Infobus.
Yes, there is Wifi on board the coach from Palermo to Brindisi with the following coach company: FlixBus, Sais Autolinee, Infobus.
popular bus stations
Popular bus stations from Palermo to Brindisi
Palermo
Brindisi
Most popular bus connections from Palermo
More options for your journey from Palermo to Brindisi
Here are some other resources that might have the information you need
Most popular buses to and from Brindisi and Palermo
Most popular bus connections to Brindisi
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