The cheapest and fastest buses from Pisa to Rome
Cheapest price
€17
Average price
€28
Fastest journey
3 h 10 m
Average duration
3 h 44 m
Buses per day
15
Distance
265 km
The best way to find a cheap bus ticket from Pisa to Rome is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Pisa to Rome will cost around €28 if you buy it on the day, but the cheapest tickets can be found for only €17.
Of the 15 buses that leave Pisa for Rome on Sat, Apr 04, 11 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Sat, Apr 04 the direct buses cover the 265 km distance in an average of 3 h 44 m but if you time it right, some buses will get you there in just 3 h 10 m .
On Sat, Apr 04 the slowest buses will take 4 h 10 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus6:05 AM4h45Pisa, Aeroporto Parcheggio Aurelia10:50 AMRoma, Autostazione Tiburtina€171One-way0 transfers
FlixBus10:00 PM4h35Pisa, Via delle Fiamme Gialle (Park Pietrasantina)2:35 AMRoma, Autostazione Tiburtina€191One-way0 transfers
FlixBus5:25 PM5h10Pisa, Via delle Fiamme Gialle (Park Pietrasantina)10:35 PMRoma, Autostazione Tiburtina€221One-way0 transfers
10:00 AM4h10Pisa2:10 PMRome€251One-way0 transfers
11:00 AM4h00Pisa3:00 PMRome€251One-way0 transfers
10:30 AM3h10Pisa1:40 PMRome€271One-way0 transfers
11:30 AM3h30Pisa3:00 PMRome€271One-way0 transfers
8:00 AM3h50Pisa11:50 AMRome€291One-way0 transfers
11:00 AM4h00Pisa3:00 PMRome€251One-way0 transfers
10:00 AM4h10Pisa2:10 PMRome€251One-way0 transfers
Travel Information
Compare bus and train for Pisa to Rome
Omio recommends booking the train as it is the most popular option from Pisa to Rome among Omio's users. If you are prioritising price take the bus with prices starting from €12. For those with little time consider booking a train which can get you there in 3h 36m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.2kg. The ticket price range depends on the travel mode: a bus costs an average of €12, and a train costs an average of €20.
Distance: 265 km
Compare bus with
| Bus | Most popular Train |
|---|---|
€19 Average price Cheapest | €26 Average price |
5h 15m Average total duration 4h 45m Onboard + 30m Additional time* | 4h 6m Average total duration Fastest 3h 36m Onboard + 30m Additional time* |
0.3 - 0.7kg CO2 emissions | 0.1 - 0.2kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Pisa to Rome bus times
The table below shows live departures for Pisa to Rome buses for today, Friday, April 3. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus | 8:00 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 4h35 | 12:35 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 10:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 5h30 | 3:55 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
| Saturday, April 4 | |||||
FlixBus | 4:05 AM Pisa, Aeroporto Parcheggio Aurelia | 4h45 | 8:50 AM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 5:15 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 6h05 | 11:20 AM Roma, Autostazione Tiburtina | 1 transfer | |
207 | 6:20 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 6h00 | 12:20 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus · FlixBus | 7:40 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 6h25 | 2:05 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 10:00 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 5h25 | 3:25 PM Roma, Autostazione Tiburtina | 1 transfer | |
FlixBus · FlixBus | 10:00 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 6h05 | 4:05 PM Roma, Autostazione (Metro Anagnina) | 1 transfer | |
FlixBus | 11:25 AM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 5h10 | 4:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
FlixBus | 3:25 PM Pisa, Via delle Fiamme Gialle (Park Pietrasantina) | 5h10 | 8:35 PM Roma, Autostazione Tiburtina | 0 transfersDirect | |
Find all the dates and times for this journey
Compare prices and tickets Pisa to Rome by bus or train
Compare bus and train prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Apr 04
Apr 05
Apr 06
Apr 07
Apr 08
Apr 09
Apr 10
Apr 11
Apr 12
Apr 13
Apr 14
Apr 15
Apr 16
Apr 17
Apr 18
Apr 19
Apr 20
Apr 21
Apr 22
Apr 23
Apr 24
Why should you book Pisa to Rome buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Marino Autolinee, Busitalia or Itabus to find the best option for your trip from Pisa to Rome.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are bus and train to ensure you get the best deal for traveling from Pisa to Rome.
Why book with Omio over Wanderu, Trainline or Checkmybus?
- Compare with other providers: On Omio, you can also compare tickets for the likes of Marino Autolinee, Busitalia or Itabus to find the best option for your trip from Pisa to Rome.
- Multiple modes of transport: Omio allows you to compare travel options including bus and train to find the ideal travel option from Pisa to Rome.
Journey information
Overview: Bus from Pisa to Rome
Buses from Pisa to Rome run on average 11 times per day, taking around 4h 45m. Cheap bus tickets for this journey start at €12 if you book in advance.
There are 8 buses per day. The earliest bus runs at 00:01, the last at 23:54. The fastest bus covers the 265 km distance in 4h 14m.
Distance 265 km |
Average bus duration 4h 45m |
Cheapest ticket price €12 |
Buses per day 11 |
Direct buses 8 |
Fastest bus 4h 14m |
First bus 12:01 AM |
Last bus 11:54 PM |
Bus providers: FlixBus, Marino Autolinee, Busitalia, BlaBlaCar, Itabus from Pisa to RomeYou can travel by bus between Pisa to Rome with FlixBus, Marino Autolinee, Busitalia, BlaBlaCar, Itabus for as low as €12. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Marino Autolinee
Itabus
Busitalia
BlaBlaCar
FAQs: Bus from Pisa to Rome
Find answers to the most common questions about traveling from Pisa to Rome by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Rome, this guide helps you travel smarter and with confidence.

- Marino Autolinee
- Assistance
- Priority seating
- Accessible restrooms.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Busitalia
- People with disabilities or reduced mobility have the right to free transport of their folding wheelchair or mobility aids in the luggage compartment, and assistance dogs and companions travel free of charge if continuous assistance is required.
- Marino Autolinee
- You can cancel your ticket up to 24 hours before departure for a full refund. Cancellations within 24 hours incur a 50% fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Busitalia
- Vouchers are issued for cancellations made before departure, which can be used for future purchases within one year.
- Marino Autolinee
- One carry-on bag up to 10kg (55x40x20 cm) and one checked bag up to 20kg (80x50x30 cm).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Busitalia
- One piece of hand luggage (50x30x25 cm, max 10 kg) and one piece of hold luggage (80x50x30 cm, max 20 kg) are included free of charge.
- Marino Autolinee
- 10€ per additional bag up to 20 kg.
- FlixBus
- Additional luggage can be purchased for a fee.
- Busitalia
- An additional hold luggage item (80x50x30 cm, max 20 kg) or special baggage (total volume not exceeding 240 cm, max 30 kg) can be purchased.
- Marino Autolinee
- Small pets allowed in carriers
- larger pets must be leashed and muzzled.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
- Busitalia
- Small pets (cats or small dogs) are allowed free of charge if held and not disturbing other customers
- medium and large dogs require a ticket and must have a muzzle and leash.
popular bus stations
Popular bus stations from Pisa to Rome
- 06:00-23:00
- Free Wi-Fi
- Ristorante Italiano (in the station)
- Fast Food Express (in the station)
- Caffè del Terminal (in the station).
- Available outside the arrivals terminal.
- Elevators, ramps
- Available in the station.
- Bus: 520, 720 Train: Leonardo Express
Most popular bus connections from Pisa
More options for your journey from Pisa to Rome
Here are some other resources that might have the information you need


