The cheapest and fastest buses from Prague to Karlsruhe
Cheapest price
€58
Average price
€76
Fastest journey
8 h 10 m
Average duration
8 h 33 m
Buses per day
20
Distance
452 km
The best way to find a cheap bus ticket from Prague to Karlsruhe is to book your journey as far in advance as possible and to avoid traveling at rush hour.
The average ticket from Prague to Karlsruhe will cost around €76 if you buy it on the day, but the cheapest tickets can be found for only €58.
Of the 20 buses that leave Prague for Karlsruhe on Thu, Apr 02, 8 travel direct so it’s quite easy to avoid journeys where you’ll have to change along the way.
On Thu, Apr 02 the direct buses cover the 452 km distance in an average of 8 h 33 m but if you time it right, some buses will get you there in just 8 h 10 m .
On Thu, Apr 02 the slowest buses will take 8 h 45 m and usually involve a change or two along the way, but you might be able to save a few pennies if you’re on a budget.
FlixBus6:40 AM8h35Praha, ÚAN Florenc3:15 PMKarlsruhe Hbf€581One-way0 transfers
FlixBus3:10 PM8h40Praha, ÚAN Florenc11:50 PMKarlsruhe Hbf€581One-way0 transfers
FlixBus2:30 PM9h20Praha, Černý Most11:50 PMKarlsruhe Hbf€581One-way0 transfers
FlixBus · FlixBus10:55 AM10h25Praha, Na Knížecí9:20 PMKarlsruhe Hbf€621One-way1 transfer
FlixBus · FlixBus4:15 PM11h10Prague, Central Train Station3:25 AMKarlsruhe Hbf€631One-way1 transfer
FlixBus10:25 PM8h10Praha, M. Horákové (Hradčanská)6:35 AMKarlsruhe Hbf€871One-way0 transfers
FlixBus6:40 AM8h35Praha, ÚAN Florenc3:15 PMKarlsruhe Hbf€581One-way0 transfers
FlixBus10:00 PM8h35Praha, ÚAN Florenc6:35 AMKarlsruhe Hbf€871One-way0 transfers
FlixBus3:10 PM8h40Praha, ÚAN Florenc11:50 PMKarlsruhe Hbf€581One-way0 transfers
FlixBus · FlixBus9:50 PM8h45Praha, Na Knížecí6:35 AMKarlsruhe Hbf€841One-way1 transfer
Travel Information
Compare train and bus for Prague to Karlsruhe
Omio recommends booking the train as it is the most popular option from Prague to Karlsruhe among Omio's users. If you are prioritising price take the bus with prices starting from €28. For those with little time consider booking a bus which can get you there in 6h 40m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.1 - 0.4kg. The ticket price range depends on the travel mode: a bus costs an average of €28, and a train costs an average of €26.
Distance: 452 km
Compare bus with
| Bus | Most popular Train |
|---|---|
€41 Average price Cheapest | €66 Average price |
7h 10m Average total duration Fastest 6h 40m Onboard + 30m Additional time* | 9h 42m Average total duration 9h 12m Onboard + 30m Additional time* |
0.5 - 1.1kg CO2 emissions | 0.1 - 0.4kg CO2 emissions Lowest |
![]() Most popular bus company | ![]() Most popular train company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Live departures
Prague to Karlsruhe bus times
The table below shows live departures for Prague to Karlsruhe buses for today, Wednesday, April 1. You can also manually refresh the results below to see updated bus journeys.
| Provider | Departs | Duration | Arrives | Transfers | Tickets |
|---|---|---|---|---|---|
FlixBus · FlixBus | 5:25 PM Praha, Zličín | 11h10 | 4:35 AM Karlsruhe Hbf | 1 transfer | |
FlixBus · FlixBus | 6:20 PM Prague, Central Train Station | 10h15 | 4:35 AM Karlsruhe Hbf | 1 transfer | |
FlixBus · FlixBus | 7:50 PM Praha, Na Knížecí | 8h45 | 4:35 AM Karlsruhe Hbf | 1 transfer | |
FlixBus | 8:00 PM Praha, ÚAN Florenc | 8h35 | 4:35 AM Karlsruhe Hbf | 0 transfersDirect | |
FlixBus | 8:25 PM Praha, M. Horákové (Hradčanská) | 8h10 | 4:35 AM Karlsruhe Hbf | 0 transfersDirect | |
FlixBus · FlixBus | 12:30 AM Prague, Central Train Station | 11h25 | 11:55 AM Karlsruhe Hbf | 1 transfer | |
FlixBus · FlixBus | 1:50 AM Prague, Central Train Station | 11h25 | 1:15 PM Karlsruhe Hbf | 1 transfer | |
FlixBus · FlixBus | 2:10 AM Praha, Na Knížecí | 11h05 | 1:15 PM Karlsruhe Hbf | 1 transfer | |
FlixBus | 4:40 AM Praha, ÚAN Florenc | 8h35 | 1:15 PM Karlsruhe Hbf | 0 transfersDirect | |
FlixBus+ FlixTrain | 5:55 AM Praha, Na Knížecí | 11h32 | 5:27 PM Karlsruhe Hbf | 1 transfer | |
FlixBus · FlixBus | 7:00 AM Prague, Central Train Station | 10h35 | 5:35 PM Karlsruhe Hbf | 1 transfer | |
FlixBus · FlixBus | 7:40 AM Praha, Na Knížecí | 10h35 | 6:15 PM Karlsruhe Hbf | 1 transfer | |
FlixBus | 8:30 AM Praha, ÚAN Florenc | 10h50 | 7:20 PM Karlsruhe Hbf | 0 transfersDirect | |
FlixBus · FlixBus | 8:55 AM Praha, Na Knížecí | 10h25 | 7:20 PM Karlsruhe Hbf | 1 transfer | |
FlixBus | 10:50 AM Praha, ÚAN Florenc | 9h05 | 7:55 PM Karlsruhe Hbf | 0 transfersDirect | |
FlixBus · FlixBus | 10:55 AM Praha, Zličín | 10h55 | 9:50 PM Karlsruhe Hbf | 1 transfer | |
FlixBus | 11:05 AM Prague, Central Train Station | 8h50 | 7:55 PM Karlsruhe Hbf | 0 transfersDirect | |
FlixBus | 12:30 PM Praha, Černý Most | 9h20 | 9:50 PM Karlsruhe Hbf | 0 transfersDirect | |
FlixBus | 1:10 PM Praha, ÚAN Florenc | 8h40 | 9:50 PM Karlsruhe Hbf | 0 transfersDirect | |
FlixBus · FlixBus | 2:15 PM Prague, Central Train Station | 11h10 | 1:25 AM Karlsruhe Hbf | 1 transfer | |
Find all the dates and times for this journey
Compare prices and tickets Prague to Karlsruhe by train or bus
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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Why should you book Prague to Karlsruhe buses with Omio?
Why book with Omio vs FlixBus?
- Compare with other providers: On Omio, you can not only buy tickets for FlixBus, but also compare tickets for the likes of Infobus to find the best option for your trip from Prague to Karlsruhe.
- Designed for International Travelers: Omio is in your language including 24/7 customer service and offers multiple payment options, including PayPal, credit cards, and bank transfer, in your preferred currency.
- Compare all your options: Omio allows you to compare FlixBus with all available travel options, which are train and bus to ensure you get the best deal for traveling from Prague to Karlsruhe.
Why book with Omio over Wanderu, Trainline or Busbud?
- Multiple modes of transport: Omio allows you to compare travel options including train and bus to find the ideal travel option from Prague to Karlsruhe.
Journey information
Overview: Bus from Prague to Karlsruhe
Buses from Prague to Karlsruhe run on average 20 times per day, taking around 6h 40m. Cheap bus tickets for this journey start at €28 but you can travel from only €26 by train.
There are 8 buses per day. The earliest bus runs at 00:05, the last at 23:55. The fastest bus covers the 452 km distance in 8h 35m.
Distance 452 km |
Average bus duration 6h 40m |
Cheapest ticket price €28 |
Buses per day 20 |
Direct buses 8 |
Fastest bus 8h 35m |
First bus 12:05 AM |
Last bus 11:55 PM |
Bus providers: FlixBus, BlaBlaCar, Infobus from Prague to KarlsruheYou can travel by bus between Prague to Karlsruhe with FlixBus, BlaBlaCar, Infobus for as low as €26. When you search for schedules and tickets, Omio will show you the best journey
FlixBus
Infobus
BlaBlaCar
FAQs: Bus from Prague to Karlsruhe
Find answers to the most common questions about traveling from Prague to Karlsruhe by bus. From journey times and ticket prices to direct connections, first and last departures, and even whether the route is scenic, our FAQs cover everything you need to plan your trip. Whether you’re looking for the fastest bus, the cheapest option, or tips for making the most of your visit at Karlsruhe, this guide helps you travel smarter and with confidence.

- Infobus
- Assistance
- Priority seating
- Transport for wheelchairs and mobility aids.
- FlixBus
- Assistance
- Priority boarding
- Wheelchair-accessible buses.
- Infobus
- You can cancel your ticket up to 24 hours before departure for a partial refund. Cancellations within 24 hours may incur a fee.
- FlixBus
- You can cancel your ticket up to 15 minutes before departure and receive a voucher for future travel. Refund requests for delays over 120 minutes are possible.
- Infobus
- One carry-on bag up to 5kg (40x20x25) and one checked bag up to 20kg (50x30x80).
- FlixBus
- One carry-on bag up to 7kg (42x30x18 cm) and one checked bag up to 20kg (80x50x30 cm).
- Infobus
- 10€ per additional bag.
- FlixBus
- Additional luggage can be purchased for a fee.
- Infobus
- Small pets allowed in carriers
- larger pets may require a separate ticket.
- FlixBus
- Small pets in carriers allowed
- guide dogs travel for free.
popular bus stations
Popular bus stations from Prague to Karlsruhe
- 06:00-23:00
- Free Wi-Fi
- Cafeteria Florenc (in the station)
- Bistro Florenc (0.2 km)
- Restaurace U Rozvařilů (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 133, 135, 175, 207 Metro: B, C
- Free Wi-Fi
- Café Na Knížecí (in the station)
- Bistro Praha (0.2 km)
- Restaurace U Knížete (0.5 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 137, 176, 191 Metro: B
- 00:00-23:59
- Free Wi-Fi
- Czech Bistro (in the station)
- Fast Food Express (in the station)
- Bohemian Café (0.2 km).
- Available outside the main entrance.
- Elevators, ramps
- Available in the station.
- Bus: 135, 175, 207 Metro: C Train: All major s
Most popular bus connections from Prague
More options for your journey from Prague to Karlsruhe
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