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Compare train and bus for Karlovy Vary to Prague
Omio recommends booking the bus as it is the most popular option from Karlovy Vary to Prague among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €10 For those with little time, consider booking a bus, which has an average total journey time of 2h 32m. Average ticket prices depend on the travel mode: a bus costs an average of €10, while a train costs an average of €20.
Distance: 112 km
Compare bus with
Most popular Bus | Train | Driving |
|---|---|---|
€10 Average price Cheapest | €20 Average price | €31 Average price (fuel + tolls) |
2h 32m Average total duration Fastest 2h 2m Onboard + 30m Additional time* | 4h 2m Average total duration 3h 32m Onboard + 30m Additional time* | 1h 29m Average total duration (door-to-door) |
![]() Most popular bus company | ![]() Most popular train company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Compare ways to travel from Karlovy Vary to Prague
Compare the available ways to get from Karlovy Vary to Prague, with the key details around price, speed, convenience, and direct service.
This is compared to other travel options from Karlovy Vary to Prague:
A bus is €11 less than a train for this route with tickets for a train from Karlovy Vary to Prague costing on average €20.
Other travel options to Prague take longer:
Train takes on average 4h 2m.
Travel optionsfrom Karlovy Vary to Prague
How to get from Karlovy Vary to Prague by train, bus or flight.
Our recommendation
The best way to travel from Karlovy Vary to Prague is by taking a bus because it’s the best combination of price and speed.
FlixBus8:30 PM1h40Karlovy Vary, Dolní Nádraží10:10 PMPraha, M. Horákové (Hradčanská)€71One-way0 transfers
Cheapest
FlixBus8:30 PM1h40Karlovy Vary, Dolní Nádraží10:10 PMPraha, M. Horákové (Hradčanská)€71One-way0 transfers
Fastest
FlixBus6:30 PM1h35Karlovy Vary, Dolní Nádraží8:05 PMPraha, M. Horákové (Hradčanská)€101One-way0 transfers
Other options
R 61312:57 PM3h28Karlovy Vary, nádraží4:25 PMPrague hlavní nádraží€101One-way0 transfers
R 6152:57 PM3h29Karlovy Vary, nádraží6:26 PMPrague hlavní nádraží€101One-way0 transfers
R 6174:47 PM3h38Karlovy Vary, nádraží8:25 PMPrague hlavní nádraží€101One-way0 transfers
FlixBus1:30 PM1h40Karlovy Vary, Dolní Nádraží3:10 PMPraha, M. Horákové (Hradčanská)€71One-way0 transfers
FlixBus12:30 PM1h40Karlovy Vary, Dolní Nádraží2:10 PMPraha, M. Horákové (Hradčanská)€71One-way0 transfers
FlixBus2:30 PM1h40Karlovy Vary, Dolní Nádraží4:10 PMPraha, M. Horákové (Hradčanská)€71One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
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FAQs: Travel from Karlovy Vary to Prague
Travel to Prague easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Karlovy Vary to Prague.

This is compared to other travel options from Karlovy Vary to Prague:
A bus is €11 less than a train for this route with tickets for a train from Karlovy Vary to Prague costing on average €20.
Other travel options to Prague take longer:
Train takes on average 4h 2m.
- Around 25 buses per day.
- Around 6 trains per day.
However, we recommend checking specific travel dates for your route between Karlovy Vary and Prague as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Karlovy Vary, nádraží and arrive in Prague hlavní nádraží.
- Buses mostly depart from Karlovy Vary, Dolní Nádraží and arrive in Praha, ÚAN Florenc.
- Travel with FlixBus to go to Prague by bus.
- Travel with České dráhy, Deutsche Bahn to go to Prague by train.
- 25 direct buses per day with FlixBus.
- 3 direct trains per day with České dráhy, Deutsche Bahn.
Travelling from Karlovy Vary to Prague: related information
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