Travel Information
Compare train and bus for Karlsruhe to Frankfurt am Main
Omio recommends booking the train as it is the most popular option from Karlsruhe to Frankfurt am Main among Omio's users. If you are prioritising price, take the bus, with an average ticket price of €13 For those with little time, consider booking a train, which has an average total journey time of 1h 39m. If you are seeking to minimise your carbon footprint, the train is your best option, with estimated CO2 emissions of 0.0 - 0.1kg. Average ticket prices depend on the travel mode: a bus costs an average of €13, while a train costs an average of €33.
Distance: 125 km
Compare train with
Most popular Train | Bus | Driving |
|---|---|---|
€33 Average price | €13 Average price Cheapest | €21 Average price (fuel + tolls) |
1h 39m Average total duration Fastest 1h 9m Onboard + 30m Additional time* | 2h 54m Average total duration 2h 24m Onboard + 30m Additional time* | 1h 45m Average total duration (door-to-door) |
0.0 - 0.1kg CO2 emissions Lowest | 0.1 - 0.3kg CO2 emissions | - CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company | Your own car or car rental |
Direct Options | Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
This is compared to other travel options from Karlsruhe to Frankfurt am Main:
A bus is €20 less than a train for this route with tickets for a train from Karlsruhe to Frankfurt am Main costing on average €33.
Other travel options to Frankfurt am Main take longer:
Bus takes on average 2h 54m.
Travel optionsfrom Karlsruhe to Frankfurt am Main
How to get from Karlsruhe to Frankfurt am Main by train, bus or flight.
Our recommendation
The best way to travel from Karlsruhe to Frankfurt am Main is by taking a bus because it’s the best combination of price and speed.
FlixBus6:05 PM2h10Karlsruhe Hbf8:15 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)€101One-way0 transfers
Cheapest
FlixBus6:05 PM2h10Karlsruhe Hbf8:15 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)€101One-way0 transfers
Fastest
STR 3 · ECE 8 · ICE 10128:24 AM1h14Europaplatz/Post Galerie (Karlstraße)9:38 AMFrankfurt Airport long-distance station€251One-way2 transfers
Other options
FlixTrain2:23 PM1h32Karlsruhe Hbf3:55 PMFrankfurt South station€131One-way0 transfers
STR 3 · ICE 2765:44 PM1h25Europaplatz/Post Galerie (Karlstraße)7:09 PMFrankfurt (Main) Hbf€141One-way1 transfer
S1 · ICE 1008:43 PM1h25Europaplatz/Post Galerie (Karlstraße)10:08 PMFrankfurt Airport long-distance station€141One-way1 transfer
FlixBus11:15 AM2h15Karlsruhe Hbf1:30 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)€101One-way0 transfers
FlixBus3:50 AM2h10Karlsruhe Hbf6:00 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)€101One-way0 transfers
FlixBus9:50 PM2h25Karlsruhe Hbf12:15 AMFrankfurt am Main, Flughafen Frankfurt (Terminal 1 - Busparkplatz P36)€101One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
Compare train and bus prices over the next three weeks. See the best deals at a glance, find the lowest fares, and choose the option that fits your budget.
Oct 20
Oct 21
Oct 22
Oct 23
Oct 24
Oct 25
Oct 26
More than 1,000 travel companies trust us to sell their tickets all in one place.
FAQs: Travel from Karlsruhe to Frankfurt am Main
Travel to Frankfurt am Main easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Karlsruhe to Frankfurt am Main.

This is compared to other travel options from Karlsruhe to Frankfurt am Main:
A bus is €20 less than a train for this route with tickets for a train from Karlsruhe to Frankfurt am Main costing on average €33.
Other travel options to Frankfurt am Main take longer:
Bus takes on average 2h 54m.
- Around 27 buses per day.
- Around 16 trains per day.
However, we recommend checking specific travel dates for your route between Karlsruhe and Frankfurt am Main as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Karlsruhe Hbf and arrive in Frankfurt (Main) Hbf.
- Buses mostly depart from Karlsruhe Hbf and arrive in Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof).
- Travel with Deutsche Bahn, TGV, FlixTrain to go to Frankfurt am Main by train.
- Travel with FlixBus, BlaBlaCar Bus, Alsa to go to Frankfurt am Main by bus.
- 8 direct trains per day with Deutsche Bahn, TGV, FlixTrain.
- 27 direct buses per day with FlixBus, BlaBlaCar Bus, Alsa.
Travelling from Karlsruhe to Frankfurt am Main: related information
Here are some other resources that might have the information you need
