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Compare train and bus for Karlsruhe to Frankfurt am Main
Omio recommends booking the train as it is the most popular option from Karlsruhe to Frankfurt am Main among Omio's users. If you are prioritising price take the bus with prices starting from €6. For those with little time consider booking a train which can get you there in 1h 42m. In case you are seeking to minimise your carbon footprint the train is your best bet as it emits only 0.0 - 0.1kg. The ticket price range depends on the travel mode: a bus costs an average of €6, and a train costs an average of €5.
Distance: 125 km
Compare train with
Most popular Train | Bus |
|---|---|
€18 Average price | €9 Average price Cheapest |
2h 12m Average total duration Fastest 1h 42m Onboard + 30m Additional time* | 2h 22m Average total duration 1h 52m Onboard + 30m Additional time* |
0.0 - 0.1kg CO2 emissions Lowest | 0.1 - 0.3kg CO2 emissions |
![]() Most popular train company | ![]() Most popular bus company |
Direct Options | Direct Options |
Additional time: Average total travel duration to departure point, security checks and transfers.
Travel optionsfrom Karlsruhe to Frankfurt am Main
How to get from Karlsruhe to Frankfurt am Main by train, bus or flight.
Our recommendation
The best way to travel from Karlsruhe to Frankfurt am Main is by taking a bus because it’s the best combination of price and speed.
FlixBus8:20 PM2h10Karlsruhe Hbf10:30 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)€111One-way0 transfers
Cheapest
FlixBus8:20 PM2h10Karlsruhe Hbf10:30 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)€111One-way0 transfers
Fastest
ICE 1026:59 PM1h02Karlsruhe Hbf8:01 PMFrankfurt Airport long-distance station€261One-way0 transfers
Other options
FlixTrain2:23 PM1h32Karlsruhe Hbf3:55 PMFrankfurt South station€111One-way0 transfers
TGV 95619:54 AM1h06Karlsruhe Hbf11:00 AMFrankfurt (Main) Hbf€131One-way0 transfers
ECE 88:37 AM1h04Karlsruhe Hbf9:41 AMFrankfurt (Main) Hbf€201One-way0 transfers
FlixBus6:05 PM2h10Karlsruhe Hbf8:15 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)€111One-way0 transfers
FlixBus3:40 PM2h25Karlsruhe Hbf6:05 PMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)€111One-way0 transfers
FlixBus5:55 AM2h15Karlsruhe Hbf8:10 AMFrankfurt, Stuttgarter Straße (Fermomnibusbahnhof)€111One-way0 transfers
Find all the dates and times for this journey by train, bus, flight, and ferry .
Compare prices and tickets Prices for trains, buses and flights
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FAQs: Travel from Karlsruhe to Frankfurt am Main
Travel to Frankfurt am Main easily. Whether you want fast, cheap or something entirely different, our travel experts have collected everything you need to know so you can find the best option from Karlsruhe to Frankfurt am Main.

This is compared to other travel options from Karlsruhe to Frankfurt am Main:
A bus is €9 less than a train for this route with tickets for a train from Karlsruhe to Frankfurt am Main costing on average €18.
Other travel options to Frankfurt am Main take longer:
Bus takes on average 1h 52m.
- Around 25 buses per day.
- Around 15 trains per day.
However, we recommend checking specific travel dates for your route between Karlsruhe and Frankfurt am Main as scheduled services by train and bus can vary by season or day of the week.
- Trains mostly depart from Karlsruhe Hbf and arrive in Frankfurt Airport long-distance station.
- Buses mostly depart from Karlsruhe Hbf and arrive in Frankfurt, Stuttgarter Straße (Fermomnibusbahnhof).
- Travel with Deutsche Bahn, TGV, FlixTrain, Süwex, Deutsche Bahn Intercity (DB IC), Deutsche Bahn Regio (DB Regional) to go to Frankfurt am Main by train.
- Travel with FlixBus, BlaBlaCar, BlaBlaCar Bus, Globtour Medjugorjie d.o.o. to go to Frankfurt am Main by bus.
- 8 direct trains per day with Deutsche Bahn, TGV, FlixTrain, Süwex, Deutsche Bahn Intercity (DB IC).
- 25 direct buses per day with FlixBus, BlaBlaCar, BlaBlaCar Bus.
Travelling from Karlsruhe to Frankfurt am Main: related information
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